skysight-inc/HackerNews huggingface dataset:
This one's a classic. It was one of the most memorable papers that I read as a grad student, so now I cover it every year in my course. Really enlightening.
$1.3M is less than you'd pay Adobe for hosting innocuous site analytics on a high-volume site for a year.
Talk to other spies via bitcoin.
That was something we noticed (eventually) as well. The presence of a founder who was clearly keen on doing something about the problem would bias the respondent, so that things that they would normally shut out of their head (like getting a job) became easy to talk about. Once the founder goes away, they get shut out of their head again.

You can compensate for this somewhat by gauging emotional response - someone whose eyes shoot open while exclaiming "You can do that?!" and then tracking you down when you walk away is probably a much better prospect than someone who says "Oh, sure, I'd use that" in a level tone of voice. But for my latest venture, I've been using a combination of AdWords and going to meetups to validate the idea: each of them tells something that the other doesn't.
How to  Actually Be More Productive to Be an Entrepreneur Badass
I love that Mithril has been surfacing as a framework to watch now that the hype cycle around angular/react is bubbling down. It struck me as one to watch years ago, and were it not for the popularity of the aforementioned the case for it could have been quite convincing. I will definitely be looking for opportunities to trial it.
The bigger question is if Google Cloud Platform is cheaper than AWS?
BTW they're Quantcast's numbers - Gawker specifically refers you to them for their traffic numbers so I guess they're feeding them their traffic stats.
Don't Be a Snob about Career Advice
5 Personality Traits That Will Help You Discover Your Hidden Leadership Skills
He might be surprised, but his whole premise was being evidence-based and upending old ways of thinking with rigorous experimentation. If this new study holds up to scrutiny, I think to think he'd be glad to have better science.
Stand-Out Leaders Putter at These 7 Basics
looks like a hard package to fill.
I didn't get that at all from either the interview or the paper.

From the paper, the conclusions seem to be: Decision theory creates a logically grounded explanation as to why high predictive value experiments are being done less often. To resolve this, research needs to be done in measuring the effectiveness of drug discovery models.

Nowhere in the article do they call for more math - the final conclusion of the paper is a call for more experiments validating existing drug models.
Oracle replication usually requires Golden Gate to the best of my knowledge. Someone was telling me the other day they hacked their own system together with shell scripts (ship and restore log files using scp etc), but that's probably not something you'd want to build your business on.

So yes, Oracle replication is probably better if you use Golden Gate. But Golden Gate is pretty expensive (17k per CPU?).
Hustle before you hack
>And you'll have to explain Rexulti and Abilify to me. Abilify isn't an antidepressant, it's an antipsychotic.

I hadn't heard about Rexulti until today, but Abilify is heavily marketed as an adjunct therapy for treatment-resistant depression.
Maybe it was for a particular implementation? Funny story: the first toy impletementation of Quantum Key Distribution used a device with rotating photon polarizers. Quantum Key Distribution is completely secure so on paper the device was too. However, you could actually hear the polarizers rotating in a way you could intercept the whole secret key... as long as you were not deaf!
there is so much here it's hard to know where to get started.
Bind XML File for Conversion to PDF and Add Drawing with Transparent Color in PDF
I'd say it is even worse than that. The years of strict agency pricing trained people to not even bother looking at competing ebookstores, entrenching Amazon's dominance.
Oh, some Javascript thing. I thought this was about the Internet backbone.
In the early days, most drug discovery (while amazing for its time) covered comparatively simpler diseases with arguably less complex physiological and pharmacological models i.e. low hanging fruit. Many of these diseases (e.g. Type 2 Diabetes) are still improperly addressed to this day. But they are not as lucrative for today's pharmaceutical company as they used to be in simpler times.

Governments and insurers are too astute to pay excessively for incremental improvements in mass or lifestyle disease categories. It makes more business sense for Big Pharma to target complex, hard-to-cure diseases that affect a small population set. While the success rate for such molecules is much lower, it's also much harder for payers to apply their usual mass-oriented drug economics to them.

One of the better examples of this is the recent introduction of Hep C "curing" drugs. Sponsors are going uncontested in pricing their molecules up to $84,000 per patient year[1,2].

With 3 million patients in the US alone, that's a TAM of $252 billion per year. For one drug category.

References:

[1] http://hepatitiscresearchandnewsupdates.blogspot.com/2014/03...

[2] http://www.grassley.senate.gov/news/news-releases/senators-s...
On the Madness of Optimizing Compilers
ended up reading this, very cool but I thought a new laptop framework was being released!
While I agree that 'significant' has a misleading connotation, 'discernible' is also misleading. 'Statistically significant' just isn't any everyday concept, and trying to phrase it as one will encourage people to make mistakes. It's a complex concept: if we tried this experiment under a certain null hypothesis, then it'd be at least this improbable to see a result at least this extreme. The most I'd be willing to cut it down, after so much confusion in its actual use, is "subjunctively improbable", with the null hypothesis and the threshold left implicit. "Eating fat had no subjunctively improbable effect on weight gain." This sounds technical and fiddly, which I think is a feature: if you don't like it, don't base your reporting on a technical, fiddly concept.

"Eating fat had no discernible effect on weight gain" sounds like getting evidence against such an effect, but it's compatible with getting evidence in favor, that's just not as strong as some threshold. That evidence could be useful in a meta-analysis, or for a decision when waiting for more information isn't practical or economical, or if the potential gain from trying the nonsignificant treatment is high and the potential loss low. (I've seen "no significant X" abused this way. Nobody should try X -- it's unscientific!)
You think that allowing corporations to move their SQL server investment off of Windows and onto Linux as a precursor to moving off of SQL server, rather than forcing them to change DBMS and OS at the same time is bad? That's what choice means.
I guess Einstein wasn't doing science because he used thought experiments and philosophical arguments instead of _real_ experiments.
>Accounting is the language of business
#warrenbuffet
Speech Recognition in the Browser at SeattleJS
At what point here do people go to jail?
The FDA can and has done that for faking lab tests.[1][2]

[1] http://www.nytimes.com/1983/10/22/us/3-ex-officials-of-major...
[2] http://pubs.acs.org/subscribe/archive/tcaw/10/i11/html/11reg...
In Quebec a lot of our modern taboo words are religious themed. Unlike many other cultures however, it's not religion that made them taboo, but rather the fact that we had a heavier than most religious presence in our political and education systems up to the 1960s, and when we 'woke up' as it were, a lot of religious terms became swear words. Today the province is much less religious than say the US, on average, and most of our swear words remain that way.
Hello Zaid,
How many units are looking to build? Which semiconductor companies have looked at? What is your upper limit on the cash you want to spend? How big is your video database?
Sorry a lot of questions, but I've some experience in this field.
Any chance you can provide names or links to those projects? I've been expecting this, have even heard rumor IBM is building Paxos into DB2, but would love to see real projects.
You're not thinking like a businessman. That purchase from Sybase 23 years ago and this announcement today have no technical justification. They're business decisions. The technical aspect is just a cost of doing business.

Their bet evidently is they can make more money selling SQL Server without Windows than with it.
Look up Banqiao at Wikipedia. The failure was only peripherally a consequence of the dam and far more one of poor system planning, poor engineering, poor management, poor communication, a thousand-year storm (1,000+ mm rain in 24 hours), resulting comms failures, and the inevitable dam failure.

A relatively small proportion of the deaths were directly due to flooding. Most occurred from disease and starvation -- far more infrastructure and response failures than the catastrophe itself.

Even given massive flooding, access to a solidly-constructed building 2-3 stories tall would suffice to provide protection from immediate risks, as would comms, evacuation and response plans, emergency and relief supplies, etc.

China is a country which in the past century has seen tens of millions of deaths from starvation alone, most recently about 20 years before Banqiao. On the scale of Chinese tragedies, of which there've been many, this was relatively modest.

And, as noted, the region is more than fully recovered.

Contrast Chernobyl and Fukushima. 30 years after Chernobyl (the anniversary will be this April), primary containment still isn't achieved. Radiation risk was presented across an entire continen, including the 450 million inhabitants of Europe. Eating of wild foods in Germany is still restricted (particularly mushrooms and boar). Fukushima likewise still hasn't stabilised five years on, and remains uncontained.

Nuclear accidents have very long risk tails.

And all of the management, engineering, communications, and response failures of Banqiao apply equally to nuclear power.

The industry is quite fond of downplaying risks. Has done so since the first experiments. Wanting a thing doesn't make it so.
I think you're projecting, or have serious mental issues, to come up with a conclusion like that from what I wrote.
Here's food for thought: What would be required to make a nontrivial fraction of TLS traffic on the web post-quantum secure? How much would it cost?

What about other legacy systems?

Actual, physical quantum computing is still in its infancy, so sure, it's hard to conjure up the wherewithal to worry. But nonetheless we have a long way to go before we can say the world is ready for real quantum attacks.
I haven't had much trouble growing skirret. It sprouts well from seed with a little bottom heat. I haven't tasted the roots yet. I'm hoping they're as good as I've read about
> When Amazon has 90% of the market it's silly to call what Apple did price fixing.

Price fixing has nothing to do with market share. Thanks to Steve's emails this was a very clear cut case for the government to make but if at this point in time you still can't see it then nothing will make you.
> Thinking about it a bit further, however, I'd counter that piping up in every thread about government spending with, "But NAP!" would actually be the trollish behavior.

Well, yes it would be, and you're starting to get to the crux of why Internet libertarians can be so irritating :-)

But I'd argue that people who bring up NAP constantly at least have the "virtue" of ideological consistency. You can't really pick-and-choose with non-aggression, without quickly devolving into pragmatism i.e. "it's okay to force everyone to do X because it has outcomes most of us agree are desirable, but we shouldn't force everyone to do Y because not enough of us desire the purported result". If you're bringing up NAP (even as a devil's advocate) for one thing, but then conveniently not even showing up for other topics, or worse yet showing up but not defending NAP and instead arguing on consequentialist or pragmatic grounds, then really all you're doing is using the non-aggression principle as a tool to defend stuff you wanted to happen anyway. I guess maybe that isn't trolling per se, but it's certainly not arguing in good faith, either.
This is amazing! Super hyped to see people building things that solves problems. Way to go.
all of these features are available already in the programmable haptics of pavlok (http://buy.pavlok.com)
Test Driven Development of a Flask API
Strip Charts for Easy Network Traffic Analysis
Go language question about learning
How do I use Go language to distribute a simple averaging function on large file?
I'm trying to learn how to program Go using a following problem: I've a rather large file (25Gb) of data. I want to compute a simple arithmetic function on a sliding window over this file. I've installed Go on 3 different machines in our network and want to use them as my Go Cluster. Please help.
Ask HN: Who are these tech executives sitting with Obama?
Ask HN: Who are these tech executives sitting with Obama?

Seated at table (http://pasteboard.co/26orWkfn.jpg; clockwise, starting at Obama):

1. Obama

2. Steve Jobs :-)

3.

4.

5.

6.

7.

8.

9. Larry Ellison

10.

11.

12.

13.

14.

15. Mark Zuckerberg

Here is the list of confirmed attendees (12 of the 15 at table):

_Carol Bartz, president and CEO, Yahoo

_John Chambers, CEO and chairman, Cisco Systems

_Dick Costolo, CEO, Twitter

_John Doerr, partner, Kleiner Perkins Caufield & Byers

Larry Ellison, co-founder and CEO, Oracle

_Reed Hastings, CEO, Netflix

_John Hennessy, president, Stanford University

Steve Jobs, chairman and CEO, Apple

_Art Levinson, chairman and former CEO, Genentech

_Eric Schmidt, chairman and CEO, Google

_Steve Westly, managing partner and founder, The Westly Group

Mark Zuckerberg, founder, president, and CEO, Facebook

Source: 2010 Mercury News article (http://www.mercurynews.com/ci_17415024)
The Secret to a Long Life May Lie in Nagano Prefecture
I see, thanks for the resource. Tough disease. I somewhat assumed that if you were getting treatment you could more or less forget about the disease but that doesn't seem to be the case. After reading some serious articles that have been published in the last three years it seems that a cure could found in the next 15 to 25 years... optimistic of course but let's hope that's the case.
He is not dead:

https://en.wikipedia.org/wiki/Steve_Ballmer
I'm still unclear under what criteria Oracle comes out on top of MSSQL. Aside from the extreme high end, I can't think of a circumstance where I'd prefer using Oracle to MSSQL.
Bed-In-a-Box Startups Challenge Traditional Mattress Makers
`Please join me Satya Nadella, Joseph Sirosh and Judson Althoff at our Data Driven .....

Thanks,
Scott
`
This is why there is a comma in grammar. `me Satya Nadella, X and Y` is different from `me, Satya Nadella, X and Y`
How can you honestly think VMs are the most secure form of isolation?
Key takeaways from this new article, for people blocked by the WSJ paywall:

"That letter cited “deficient practices” in five categories. In one of them, hematology, the problems found by inspectors posed “immediate jeopardy to patient health and safety,” regulators said.

The test that inspectors found Theranos kept doing despite the erratic quality-control results was a hematology test that measures how long it takes blood to clot, the people familiar with the matter said.

The test is an important part of the treatment regimen for patients who are at risk of strokes or have blood disorders...

People who have seen the Theranos inspection report said it seems to indicate the company ignored quality-control results for the blood-clotting test that fell short of its own criteria.

The results produced in the quality-control checks repeatedly deviated from the lab’s typical result by more than two standard deviations, those people said...

At Theranos, there were seven quality-control failures in a single day, said a person familiar with the report...

Dr. Hamill said any doctors who received prothrombin time test results from the Theranos lab during the six-month period shouldn’t rely on them and should have their patients retested as soon as possible. “Those results are not worth anything,” he said...

The federal inspectors also concluded that the Theranos lab in California used expired reagents, or substances added to blood samples to elicit chemical reactions, for some prothrombin time tests, according to the people familiar with the inspection report.

Those people said the report also found that the lab’s director didn’t have responsibility for the lab’s quality-control program and the lab’s quality-control manager was unqualified..."

EDITED TO ADD: Actually, the really key sentence is this one: "Theranos spokeswoman Brooke Buchanan said: “The PT/INR issues identified by CMS related to tests run on conventional equipment using venipuncture samples.” A CMS spokeswoman declined to comment." Because that means that these quality control problems were not due to Theranos' "revolutionary" finger-prick tests, they were from regular old venipuncture tests running on a standard machine that were giving wildly incorrect results, expired reagents, no QC in the lab, etc. Bad data is worse than no data. If they couldn't get old-fashioned labs right, no wonder they were having trouble with the finger-prick stuff.
Meet the real ironman of spaceflight: Valery Polyakov
> 131b revenue in 2015. So, at 1.3m, a 0.001% fine, aka half a minute of revenue.

It's interesting to look at it in political terms. A modern presidential campaign costs about a billion, i.e. less than one day per election. That's $7.50 for each voter in the last election, or likely more than $750 for each "undecided" voter in a competitive state.

And then you learn that lesser politicians provide as much as 40x returns...

http://abcnews.go.com/Politics/story?id=1667009
Blockchains are a horrible solution for the problem domain. Oh, you need decentralized consensus? Let's limit throughput to n / w / 0.5n. Hence bitcoin's multi-hour resolution times which are increasing geometrically. Sorry, I don't see it.
i think its pretty true - although its not just about close minded-ness. a lot of people do associate california with kim kardashian types - which i assume to mean pretty, fake and lacking in skills beyond entertainment value.

i try not to think this way myself... my own experiences clash with this sort of thinking a lot, but its a very common perception and its evidence is to be found in a lot of places sadly... helping to reinforce those perceptions.
Kick-start your product development with 600+ IoT professionals in Shenzhen
Curious thing to me is at what point do you switch from saying this was a test to this is the real thing; meaning that you task the NSA to hack someone, then blame it on for example North Korea, China, etc.
Breaking news! RSA was cracked today by a quantum computer. Turns out {3, 5} were actually universal factors.
Indeed, although Buffet did bet on an ETF, which was the index fund SPY.
Not mature or well maintained, but lightweight: http://barecss.com
so where's part two?
But how do you detect it reliably?
Hey there,

You can check out https://slemma.com, We have codeless chart creation and allow you to filter your entire dashboards without editing by any dimension in your dataset.

Here's a small example dashboard that has the filtering at the top. https://slemma.com/share/838155f8e3f51bae90befdf5e0c3b8b8428...

Plans start at $29/month for a team of 3 users.

Hope that helps,
Tech Book Face Off: Practical Node.js vs. Node.js the Right Way
Google asked to remove 100,000 'pirate links' every hour
I still remember the snow leopard sequence shown in Planet Earth. I'm definitely looking forward to see this in the new Planet Earth.
I won't keep up this conversation if you're not going to put in the effort to understand what I'm writing. The code we've been talking about is the safe manufacturer's code that only the safe manufacturer has and that takes a day of effort for the safe manufacturer to use. The equivalent for Apple is the release build key, which has exactly the same properties.

You then made further mistakes. The signed build does not need to be limited to a single device, so it has no place in the analogy. The FBI allows Apple to keep the build themselves and delete it after use.

Please try to keep up, or you'll continue to tilt at windmills, and you won't learn anything.
Analyzing the Language of the Presidential Debates
The Vast Bay Leaf Conspiracy (2016)
Can you expand on that? As I understand it blockchains allow you to use a private key as your master identity, but don't inherently provide tools for connecting that key to a real-world identity.

Are you envisioning a system like Keybase, but completely distributed?
Edin Kadribašić passed away
Those are limited use, constrained, black box user agents. There are very capable MUAs as well as simplistic mail clients. Maybe you can enable user scripts in some Android browsers.
Frank Hecker : "Accepting this bug. My initial comments: The last time I dealt with the issue of
the DoD PKI it was essentially a DoD-internal PKI for the use of U.S. military
personnel (active or retired), DoD civilian employees, DoD contractors, and
(maybe) allied forces (e.g., NATO). It was not intended for the use of the
general public (whether U.S. citizens or not), and I'm not aware that members of
the general public would ever be in a situation where they would encounter
SSL-enabled web servers, S/MIME email, or signed code that used DoD-issued
certificates.

Based on that I would consider this an "intranet" CA (albeit for a very large
intranet) and based on my previous "meta-policy" comments I would recommend
not including this in Mozilla et.al. I'll leave this bug open for a period of
public comments, and then I'll close it with "WONTFIX" unless someone can
provide compelling reasons why I should do otherwise."

Seems reasonable to me.
In that case, I would recommend Rust because it's just harder to learn than the other options.
Exploratory Data Analysis of the Flint Michigan Water Crisis: Part 1
It sounds like you haven't used MSSQL in quite a while. The 2012-2016 editions have progressed significantly. 2000-2008 were pretty vanilla but then most databases of that era were.

Pricing can be expensive if you need the standard, BI, or Enterprise editions but otherwise it's not. It's no where near the cost of Oracle though.
I think grandparent poster is saying app devs should program directly to the built-in Apple syntax rather than using a third-party library which wraps it. Because if Apple comes out with extensions or changes, then anyone who uses Stevia will need to wait until the library incorporates them, losing their advantage to competitors in the process.

I sympathize somewhat with the grandparent poster's point, but it all depends on how likely Apple is to improve auto-layout vs. how many new developers need an easier layout system now. JQuery managed to become massively popular on the web, despite web browsers eventually adopting most of its innovations, because the browsers took years to incorporate its innovations (and sometimes never quite got the syntax right) while millions of people needed to make a webapp right now.
I guess Oracle owns CDDL license stewardship now. It would be really interesting if they released CDDL-2.0 that just lets you relicense things under the GPL. The might do that, after all, execs from their predecessor, Sun, liked the GPL. Also they put Berkely DB under the AGPL.
'I obviously don’t know what happened at the other company, but I do know that Michelle had no intention of breaking any laws and no idea that she’d broken any laws'

This. This is terrifying. We're already in the position, as a society, that everyone is guilty of something, and it's just whether someone feels like prosecuting you or not as to whether you'll be penalized.
Ahh man, I needed this laugh. Thank you.