skysight-inc/HackerNews huggingface dataset:
One of the features I always liked about Perl, which I felt set it apart from other languages, is the way regular expressions are part of the language syntax rather than an OOP library. In other languages, regular expressions seem very clumsy to use, while in Perl they're very natural. This is most evident when you're trying to use capturing parentheses; the differences between Perl and, say, C#, are huge.

Back in the day, I thought it would be a great addition to Perl if xml/html was also added to the language syntax. This was before html templating systems existed, and CGI.pm wasn't a good choice for my web application, so my code was full of print statements, quoted strings containing html, and having to use qq!...! for my quotes to avoid problems with " and ' characters in the output I wanted.

When I first saw JSX it seemed like a great thing, finally satisfying that old desire to have html markup as a native language syntax feature. I feel like it can be transformative, in the way you write your code, just like Perl's regex syntax or like having functions as first-class values can be in functional languages.

Having used React.js a bit, I'm not so sure. But I'm probably biased because I don't think React.js fits well with what I'm trying to do: ASP.NET MVC web applications that are mostly traditional full-page-refresh style apps, with some SPA-like AJAX-based interaction on some pages. I wanted to use React.js for those SPA-like pages, but it doesn't integrate well (or at all) with Razor-based server-side rendering, and in my testing it had a significant 1000ms+ startup time when the page loaded even for pretty trivial components, with caching of the React and Babel javascript files.
The proportion of HDR (ie HindIII reads only) without the template. What percent of cells will randomly mutate to get HindIII recognition sites?

Also, seeing what happens using template only would be good. We would expect low baseline levels of HDR to occur right? I it is plausible few out of 10^5 or 10^6 cells will require repair at that locus even without any Cas9.
> Very few of us actually give a shit about doing something novel.

Most novelty presents outside of business in general, including startups. Startups generally are applying the novelty (that is no longer novel) that is perceived as potentially valuable to see if it actually is.

Ideally, startups should be focused on doing something _well_, rather than doing something _novel_. To the extent that novelty occurs, it should be a side effect of that objective.
Got it, it's a good point and worth looking at. Doctors taking lot's of notes while in with a patent could also lead to worse outcomes as they are distracted.

However, ~50% increase in healthcare costs would need to have a huge impact on patent outcomes or drastic fraud reduction to be worth it.
They don't mention Doggerland, a huge piece of land between the UK and Europe that sank into the sea some 8000 years ago. https://en.wikipedia.org/wiki/Doggerland
ArpON 'ARP handler inspection' 3.0 next generation
Yeah, that's a valid concern for sure. I'm very worried about how much insurance companies make and how much control they have over prices. Seems like a conflict of interest to be the insurance company and the boss of the person you are paying through that insurance.
Window size has been noticeably reduced because of rollover safety requirements, and better aerodynamics.

I have a 2011 Crown Victoria - which compared to a 2011 Charger is night and day difference.
Not EXACTLY the same thing, but there's a really neat Jason Scott talk from Defcon 18 that goes into some of the history of crack screens from early software. [0]

[0] https://www.youtube.com/watch?v=a5AceLYWE1Q
It's one thing to needlessly criticize a new business (start up), or an espoused goal (hyperloop) but a completely different situation when bringing in some run-of-the-mill skepticism. I think skepticism is healthy - it's one of those interesting emotional/intellectual mechanisms. In the most effective circumstances, skepticism seems to blend past experience + current facts + future hypothesis, all of which fit into the context of the referenced article.

Generally I don't bring much of any philosophy into the skepticism approach. Every once and a while though, it does play a role. I'm not really proud of it, but I'll publicly admit that I was so utterly repulsed by the Aurous concept that I did a little happy dance when market forces (i.e. the RIAA) took on Aurous, shut it down fast, and moved on from the dead carcass. Am I happier for its demise? Yep.
The "visiting assistant professor" treadmill is definitely in the same badness league as adjuncting. Another trap is the "tenure track positions" where no one actually gets tenure, and they end up being re-advertised every three years.
"End notes work… if the software can return back to where I came from. The Kindle can't."

The kindle can, if the links exist. If they don't, it's the publisher's fault.
I hardlink them instead. Then I can prune them from the torrents folder without affecting the organized file.
> Mercurial also ran on Windows far, far earlier than Git did. A few projects (notably Mozilla) selected Mercurial for that reason, because they had developers on Windows.

Ouch, yet another way in which running on Windows can lead to poor technical decisions.

In my own case, I really preferred hg's command congruence to SVN; git's deceptive similarity took a long time to get over.

> I originally saw the index as an obstacle to the commit model I'd gotten used to from subversion. Today, I find it a critical part of git's culture of making small commits with one logical change each.

Same here, on both counts. I'd never go back, now, but it did take time to understand the benefits.
Sure, though clearly I need to explain that it's not symmetric. I don't expect a filter to output a beautiful image. It is possible for some filters to be neutral while others spit out "ugly" results. And, of course, ugly is strictly my biased personal opinion, not an objective result.

What makes filters more ugly to me is filters that aren't very functional as a building block or a node in the middle of an image processing graph. When I said aesthetically unpleasant, I was thinking about design too, not just the aesthetics. Filters that include any aesthetics at all, frankly, are not very useful, and that is the main problem with many of G'MICs (and ImageMagick's) filters. Photoshop has some too.

I'm using https://gmicol.greyc.fr/ as the reference for filter names.

G'MIC Filters that are useful as a building block (filters you're likely to find used by professionals), and are not aesthetically unpleasant:

Basics, Colors|Channel Processing, Contours|Difference of Gaussians, Degradations|Blur, Details|Sharpen, Repair|Upscale

A small sampling of G'MIC Filters that are aesthetically unpleasant to me, primarily because they are poor building blocks (less likely to be used in professional work), secondarily because they add an aesthetic that I personally don't like, and try to do too much:

Arrays|Puzzle, Artistic|Ellipsionism, Deformations|Rain drops, Frames|Tunnel, Lights & Shadows|Shadow Patch, Patterns|Hearts, Rendering|Cupid, Sequences|Lava Lamp

Note that many of these could be re-created easily using proper image processing building blocks, like an over operator for compositing, or an expression node for image warping.
The idea is that the cable would be one long crystal, not sections. You'd have to continuously extrude the crystal from orbit to the ground or something. You can't bolt in new pieces. Whatever the solution will be, cheap is not one of the answers. Just the maintenance on it would be a world-wide effort. And for what? Cheap orbital travel? The real hard part is to find a reason to leave Earth that the oceans and Antarctica don't already fulfill. The only one I can think of is orbital foundries or other processes that need 0g. Living space we have a lot of, though cold, Antarctica has air, something Mars and Venus do not.
Wait, what?

How do you statistically compensate for a sample size of one, or zero?

The issue here isn't contaminants in the sample, it's the markers (i.e., what is being tested for) in the sample. If marker isn't uniformly distributed, then these small samples might not even find it in them.
>"No pre-existing cells have the mutation at the site you're trying to engineer. It just doesn't happen."

Not in any paper on CRISPR I have read, in fact just the opposite: there are always low levels of mutants found in the controls (eg Schumann et al 2015 linked below). Please link to the papers that have lead you to make this claim.
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Uh... Isn't the fix to just stop taking more patients than you can handle comfortably and enjoyably? Maybe that, paired with encouraging more of the younger generation to become doctors (to cover for the patients you feel like you might be abandoning?)?

Doctors are extremely valuable workers/members of society, I'm surprised that they don't feel more in-control of the situation (if you want shorter notes, push for it?)...

Also, this assumption that constant note taking makes someone feel like they're not being treated as human isn't completely convincing either... If my doctor takes notes while I speak to him/her (and it was made clear at least once that I have their attention), that impresses on me that they're doing their job, which is far more important to me than the feeling of being treated like a human for an hour.

Also, why not just take micro breaks during billable time to do notes? bill for the 45 minutes, notes for 15 mins, take notes right in front of the person, and let them know what is happening?

Maybe this just seems easy to fix to me because I'm an outsider
Uh, I don't know: IM chatting is anything but "instant". It's pretty slow, actually. I don't really feel it while in conversation, but if I look at times each message was posted afterwards — it's easy to notice that conversation of the same volume would be done much quicker verbally. Waiting for everyone to respond on the top of it would be so slow it would kill the conversation.

I don't speak sign language, but I observed others doing that and it seems to be almost as fluent as talking verbally. While both parts are involved in conversation most of the time — it's something we do as we speak verbally as well: making facial expressions, nodding, saying "uh-huh" and inserting little jokes.

I never actually noticed that deaf people really tell stories at the same time: one of them usually seems like listening. So, I'd actually want some reference that would prove that deaf people really do "speak simultaneously".
Interesting - if I understand correctly, you're saying that you didn't notice for a month that no color balance was happening. Then perhaps an even simpler experiment preliminary experiment could be done to just see how well subjects are able to guess if a screen has been color balanced at night. If most people can't tell most of the time, then that simplifies doing an efficacy experiment.
Amex Marketing Executive Tops Twitter CMO List
Wish I could find an adult intro to auto mechanics class around here. That would be massively useful for everyone to learn but it seems like all anyone who already knows basic auto repair says is "YOU DON'T KNOW HOW TO DO THAT?!" with a sarcastic condescending tone, and I guess that attitude filters down to lack of education since it is obvious or whatever.

But on the positive note there is a 101 to gun safety class every two city blocks so I have that going for me...
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former Zappos engineering manager here. still with the company, just not a manager any more.

this latest round of news stories all stem from the offer that was given in may being extended to a select group who were deemed critical to finishing the "supercloud" migration. that extension ended in january, so another "exodus" occurred as a new round of people took the offer. since the project was a tech project, this new round was almost 100% from tech.

the ones who accepted this latest round were heavily tilted toward managers. mostly product or project managers with a healthy smattering of engineering managers. out of all the engineering managers (~15), there are only 2-3 of us left. we are the ones who took on active roles in writing software and making an impact by doing rather than commanding (https://medium.com/zappos-engineering/elastic-beanstalk-vs-a...).

fwiw, from my perspective, the story is far from over. i feel like it is only now that we can really progress the hard work of self-organization. the extended offer was holding us back. it's tough to move forward with distributed authority when you know that a good portion of your peers are not interested in that distributed authority.

i guess the message i'm trying to get across now is that for those of us here and moving forward, it's far from a "finished" project. it's certainly not a "failed" experiment yet. it feels like it's just starting.

and we are starting to see some of the benefits of people self-organizing. one example is that for the last couple of years we've tried to contribute to open source. i'm not entirely sure why we weren't able to do so except to point at bureaucracy and traditional management putting up roadblocks. if your manager doesn't see how you working on open source is going to help them out, then you have much less incentive to contribute to open source.

in a self-organized system, with the directive being "figure out what the best use of your time is for the purpose of the company," when an individual senses that contributing to open source benefits the company, then they can do it. since the tearing down of the traditional management hierarchy, we've had an open source project released and are deep into releasing a second.

it's hard to say this never would have been possible under the traditional hierarchy, but it is accurate to say that it didn't happen after two years of trying and then happened within months with self-organization.
hg could be 20% better than git. For the sake of the arugment, let's say it is.

git's network effects mean hg needs to be 1000% better than git to replace it (much like git replaced svn, svn replaced cvs, and cvs replaced rcs).
Stubhub.
This lib is so small and self-contained that it was straightforward to port it to Windows (Visual Studio):
https://github.com/jetpacapp/DeepBeliefSDK/pull/62

I had trouble getting Caffe and Torch to run natively (i.e. MS toolchain), anyone knows of a good Windows port for these that one can link to?
The Malibu name is already over 50 years old, actually. It would have been amusing to redo this test with two Malibus.
This is one of the albums that are nicer to have on cd instead of vinyl. I mean who wants to interrupt a good dopesmoker session by having to get up from the couch every 20 minutes to flip the lp?
Yep, you're right. From the about section: "A weekly dose of breaking-smart ideas for individuals and organizations based on ongoing research. In tweetstorm form."
Is WordPress Code Really a Mess?
Someone in Brooklyn Built an Igloo in the Blizzard, Then Listed It on Airbnb
I think some of this stuff will retain its coolness with future generations even though they didn't experience it first hand. Kind of like the way I distributed copies of the Hacker Manifesto when I was in high school even though I was an infant when Mentor wrote it.
I assume that's why, at 6'5", I can't see out the damn windshield anymore. I'm looking straight into the visor,and rear view mirrors keep getting lower. It's all really frustrating.
Yes. Also, it will build faster and the configuration will probably be simpler. That's been my experience having used Browserify with Gulp and Grunt for 2 years and then switching.
:D nice trolling.
I'm a bit surprised they decided on a CAFFE-like declarative language for specifying neural net architectures[1], instead of offering high-level software components that enable easy composition right from within a scripting language, e.g., like Python in TensorFlow's case.[2]

Is there anyone from the Microsoft team here that can explain this decision?

--

[1] See examples on https://github.com/Microsoft/CNTK/wiki/CNTK-usage-overview

[2] See examples on https://www.tensorflow.org/versions/0.6.0/get_started/index....
Having someone's personal identity nummer (personnummer) is in itself enough to do a lot of damage.

Many Swedish online shops will happily send you goods along with an invoice that you pay later. The invoice option is often only available if you provide your personnummer - which as I mentioned is public information, a phone call away - and have the goods sent to the address tied to that number. If you live in a house with a mailbox outdoors, a thief could order stuff to your address and empty the mailbox before you. "Stuff" could also be things like mobile phone subscriptions and whatnot.

Or, having your personnummer, someone could send a form to the tax agency to have your official address changed! I believe they do send a letter to the old address saying the address has been changed to <new address>. But there's time to do bad stuff in between the time of the change and your discovery of it. (If, indeed, you do discover it. You might be traveling somewhere, a fact that might've been gleaned from your social media activity.)

And, as breakingcups points out above, even if it were the case that sound security procedures were implemented in Sweden, that wouldn't matter much for the numerous non-Swedish services most Swedes use every day.

Anyway -- people being able to do stuff in your name is just one thing. I don't want the whole world to know my address, or marital status, or date of birth, etc - period. It's about privacy.
Mods regularly ban accounts which post comments they disagree with, they'll state it breaks guidelines but the truth is they just don't accept certain speech here.
same with my puerto rican wife's family. could be a hispanic thing.

slightly tangential, but on the loudness part of it, funny theory I have is that, and I noticed this when I've visited her family in their hometown, since they live outside of any big city, nature itself is so loud, they have to talk louder and louder to hear each other! ;-) especially at night, there are so many noises coming from nature itself. here in mainland US, in so many places I've been to, from Maine down to the south, from El Paso to San Fran, night time is so much more quiet! anyway, that's my theory until proven otherwise haha :)
OpenResty is wonderful.

My employer sells an authorization and access control engine that can be queried by simple REST calls. We produced a small lua module that makes it simple to use from an `_by_lua_` directive.

Our customers (and internal teams) love it -- for the most part they use it to provide basic access control to simple web services, but some have done really sophisticated things things, such as deciding what privileges an HTTP request requires based on the body, query parameters, method, and headers.

HTTP clients can simply provide an authentication token issued by our services in a header, and everything works like magic.

At some point we were considering writing our own nginx module, and while we have the engineering talent to pull this off, OpenResty is just so much simpler, so it won the day hands down.
> with email and plaintext password

It's totally reasonable to transmit a password in clear if it's being transmitted inside of an SSL tunnel (which it is in this case).

Most if not all techniques that would allow for not transmitting the password in a server-decryptable fashion would require the password or a password equivalent to be stored in clear on the server.

In case of a breach, that would be devastating.
Reminds me of the classic Chevrolet Corvairs which were equipped with a single-piece steering column that could impale the driver in a head-on collision.
Amazon should simply treat users with active 2FA accounts as high security accounts. High security accounts must go through a much more rigorous validation when speaking with support.
Keep in mind, Theranos had a pretty good PR ride. I think you'd have a hard time making the case that anything that has been constant about the company is a cause of the negative sentiment.

Far more likely is that their is a growing belief that they are not "fake it 'til you make it", but rather just "fake it", and a fear that if left unaddressed, this will harm the ecosystem as a whole.
Looking at the data, it is not that people are reacting in 7ms, but that people sometimes start talking before their partner has finished, and the mean ends up at 7ms. It seems that the Japanese are more prone to interrupting others:
http://www.pnas.org/content/106/26/10587/F2.expansion.html
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Wouldn't be surprised. My family is Finnish but this is basically how we talk in a lot of situations. It's fun watching chatterboxes adapt to the long periods of quiet between phrases.
Thanks, I hope you are able to find people who are more understanding. My personal opinion is that people who haven't experienced depression, abuse, or poverty can't understand it. This might just be based on my own experience since I was raised in a family who judges and minimizes those things and I doubt they'll ever change.
Don't forget IBM released SystemML
HTML5 Responsive Frameworks for Web Developers
White House’s Shannon: “The Threats Are Bigger Than They’ve Ever Been”
Midsize family sedans have absurdly small interiors these days. Maybe it's the horribly large dash boards, but they just have no room. I hate them.
The Boom in Cybersecurity Investing
I wish that that someone did some tests between old and new software, I bet uptime of old software/hardware would be higher than our current tech stack.
I doubt what they are doing is causing more harm than opportunity cost. The things they mentioned help in the short term. While internet addiction is still in contention there already are empirically tested treatments that can do a lot better than what they talked about in the article.
I agree that's a bad use case for openresty. But by the same token, you can move logic that doesn't belong in a particular application to a simple lua script, perhaps with delegation to another service. So in general, I think, openresty helps improve separation of concerns rather than hurting it.
You can tell the difference between people who look at your page for 10 seconds after opening it 10 minutes ago, and people who actually look at your page for 10 minutes.

If you aren't fooled into thinking that particular people like your page when they don't, you can better know which demographics your pages appeal to, and which pages attract long stays generally.

You can make more informed decisions about who to advertise to and who isn't interested, which pages to invest time and money in making better, and which are fine already.