skysight-inc/HackerNews huggingface dataset:
Iron overdose is pretty dangerous, especially for children.

http://www.who.int/selection_medicines/committees/expert/18/...

Here's what WHO say:

> Several chelating agents are effective in lead excretion, but the chelator of choice depends on the blood lead concentration, the patient’s symptoms and the environmental lead burden. Symptomatic patients should be hospitalized and chelation therapy with Edetate Calcium Disodium (CaNa2EDTA). CaNa2EDTA is an intravenous formulation that has been shown to be effective with British AntiLewisite (BAL, Dimercaprol) for removal of lead in patients with encephalopathy. Edetate calcium disodium, used alone, may aggravate symptoms in patients with very high blood lead levels. When clinical symptoms consistent with lead poisoning or when blood lead levels are greater than 70 micrograms/deciliter, it is recommended that edetate calcium disodium be used in conjunction with dimercaprol.24 British-Anti-Lewisite (BAL) or dimercaprol is a small molecule drug which will cross into cells and may prevent the worsening of clinical and biochemical status on the first day of EDTA therapy.25 Oral chelating agents are available for treatment of lead poisoned patients who have elevated blood lead concentrations and asymptomatic. In the Unites States, 2,3 Dimercaptosuccinic Acid (DMSA, Succimer) is the drug most commonly used. Other oral agents that may be used are DMPS (Unithiol) and penicillamine.

Here's what CDC say about the pharmacology of chelating agents:

http://www.cdc.gov/nceh/lead/publications/books/plpyc/chapte...
You can't boil lead out of water, in the same way that you can't boil salt out of water. Metal extraction is a pretty hard problem.

It seems that you can reduce the levels of the aforementioned trihalomethane compounds by boiling though.

http://dx.doi.org/10.1155/2013/959480
@shabda Hydrogen heavy water means acidic water with high amounts of dissolved H+.
Rebecca ronald cause i love you
> more a case of social media bringing deeper problems to the surface than social media being the actual cause

I think its a combination of both. You draw a parallel between social networks and budweiser. Alcohol worsens depression and I believe social networks do as well. Whether or not they CAUSE depression is a totally different matter of course.

> depression... distorts your worldview

I think this should be up for debate as well. Even though I've echoed this sentiment myself, as someone with depression I'm starting to suspect that my own is brought on due to a very accurate understanding of the world. I've been painfully aware of my own and my family's place in the world (lower-middle-class) since I was a kid. My own and my family's mortality is another thing that makes me extremely depressed if I allow myself to think too deeply about it. Wars, world injustices, the ultimate meaninglessness of life... I've been thinking about all of this since I was around 5 years old. That's not a distorted worldview, its reality.

I think a lot of my own depression stems from the inability to block out all of the negative things in my life. Once I started meditating, stopped following the news so closely, got rid of my repressive religion, stopped letting lack of funds ruin my day (partially by blocking out all advertising), deleted my social networks and got into an excellent sleep routine I've been able to manage my depression and I feel a lot better.
Unix command-line tools
They sell you hardware cheaper and then make money selling games.
hg and svn support versioning directories. I assumed that git also did. If it does not, I stand corrected.
we have a word for that - its called the market.
What led to this particular situation was apparently rate hikes in the Detroit water system, which caused Flint to switch to using the Flint river as their water source last year. Beyond that, water systems all over the country are in bad shape. Because water rates are subject to public control, they are far too low and there is a huge under-investment in water systems:http://www.infrastructurereportcard.org/a/#p/drinking-water/...
Bash is incredibly useful, and I think more people should use it as a cross-platform default scripting language. That said, for the most compatible shell scripting, learn Bourne shell scripting. https://en.wikipedia.org/wiki/Bourne_shell
(map
(defn f [c]
{:overlap-amount (circle-overlap-distance circle c)
:mid-point (mid-point circle c)})
circle-list)

Is there a reason this uses defn instead of fn? This is the first time I've seen defn used like this.

Since this expands to something like (def f (fn [c] ... and f is never used anywhere, I'd change it to fn. If f is used, I'd consider letfn instead.

The revised code replaces it with #(...) which is shorthand for (fn [...] ...), but am curious if there was a reason for using defn or if it was just an oversight.
Is that bad? I mean how many people are willing to spring for 32GB of memory, but won't spring for a more expensive processor?

I think the 32GB in a laptop is a power user type group, and that kind of market segmentation makes sense.
France’s Antitrust Watchdog Fines 20 Courier Companies $738.7M
Actually, this is exactly the sort of guide I've been meaning to read, since I'm inclined to take the opposite view.

Too often, I think, my task is probably sufficiently simple that it could be a nice portable obviously-a-script Bash script rather than Python/whatever.
How Well Do You Know Religion?
Pebble Seizure Detect
> Jaywalking is a crime for a reason

... in some parts of the world.
As someone that commutes to work via foot (for 20 years, 4 miles round trip), living across from SF, what you describe is by far the exception. The rule? Rude and dangerous drivers not yielding to legally crossing pedestrians.

I would put the ratio of bad pedestrians to bad drivers at 1:1000.
To make money directly from your audience, your audience has to have money. The one parallel I saw in all of the article's examples is that they're all catering to young kids.

I bet someone could make a tidy fortune coming up with a monetization strategy for these artists. My guess is that targeting parents would do the trick.
This isn't an article, it's a book review; those tend to be shorter. The New Yorker also publishes a number of shorter online pieces (roughly this length). Actual articles, which appear in the weekly magazine and online, are much, much longer and in depth, such as this from the current issue[1] or another currently on the HN front page[2].

If you're interested in more, I suppose you could read the book(s). I intend on doing so.

1:http://www.newyorker.com/magazine/2015/12/14/a-house-divided

2: http://www.newyorker.com/magazine/2015/11/30/inflamed
I can't tell you the exact reasons, but I would suspect it all comes down to money. I grew up just outside of Flint, went to school in the city, and worked there for a few years. There were winters where the city couldn't afford to plow the roads. They had to lay off most of the firefighters 5 or so years ago, along with much of their police force. It is a struggling area, maybe not quite as much as Detroit, but close to it.
Off-topic, but what's the point of the "this is not medical advice" disclaimer? Your post is, patently obviously, medical advice.
More Responsive Tapping on iOS
Tool-Up Time: The 54+ Very Best Front End Web Developer Tools
The toxicity of lead is actually a longstanding political argument in the US. Lobbying against lead regulation was one of the original motivations for the development of modern american libertarianism. Even fairly recently libertarian organisations like the Cato Institute have been fighting against regulation of lead and against compensation for those poisoned.

When the topic of lead comes up on HN you often get comments arguing that it isn't really as toxic as claimed.
IMO, this is more a case of social media bringing deeper problems to the surface than social media being the actual cause.

Absolutely not. Facebook is engineered to be addictive, and happiness is based to a very large extent on perceived relative position in a social hierarchy.

Facebook is more like a horribly insidious version of advertising than food or alcohol.
Resubmitted, thanks HN mods.

Let me know if I missed any clients, I'm happy to update the post!
Simply, that is not how compassionate, caring people respond to such stories in a polite, civilized society.

In this particular instance, a doctor chose to prescribe a drug based upon a person's complete set of symptoms and medical history. And, the person, knowing his or her own set of symptoms and history, chose to follow through and begin taking an anti-depressant. This was the result of a consultation between a victim and a medical professional. Another doctor would not criticize the prescription without doing a full work up. Who are you to criticize without doing the same?

Moreover, this is a mental illness and people who suffer from a mental illness deserve nothing but support. One of the 'joys' of depression is that while you are under the cloud, you are a master at criticizing yourself.

When you add in the stigma still attached to mental illness, simply telling a personal story requires huge amounts of bravery. If you criticize or second guess the story, you provide a strong reason to stay bottled up. This is the exact opposite of what our world needs right now.

In essence, carefully criticize the system not the victim.
Blood+Brothers+2+v3.3.3+Hile+Mod+Apk+İndir-Ferhat+Özal
Yes, car drivers need to learn to drive, and that means they need to learn to slow the fuck down when there are pedestrians around.

When a car driver says "careless pedestrian" I hear "inattentive, selfish, driver".

This is probably a cultural thing, because jaywalking isn't a crime here.
Transcript of Craig Federighi and John Gruber
Why we suck at new year's resolutions and how to fix it
Warning to others: this will play audio automatically.
what's the point in this link?
You're right, they really could benefit from such training. I don't think these people know that it's a thing that businesses will pay them to consult, let alone which businesses those are or how to contact them.

I certainly don't know who I would reach out to, or how, if I had 100k instagram fans and wanted to do some consulting. How does one acquire this knowledge?
Curious about the rationalization behind creating yet another photo filters app. There are quite a few of them on iOS, its very competitive and they are all quite polished.
I was interested until I saw the price as well. I'll install Xen on something myself and save half, thanks.
I used to do that but the long versions are more understandable by other people who will look at the script.
Show HN: CodeceptJS – end to end testing framework for Node with synchronous API
I don't understand how the simulated annealing is helping.

I quote the explanation of step 4:

If the candidate tour is worse than the existing tour, still maybe accept it, according to some probability.
The probability of accepting an inferior tour is a function of how much longer the candidate is compared to the current tour, and the temperature of the annealing process.
A higher temperature makes you more likely to accept an inferior tour

Why would you need a simulated annealing for a seemingly so simple function?
More Details About the Steam Controller Assembly Process
Ah, gotcha. I struggled with PEG and left recursion for a while before finding GLL. Do you have any resources on how to combine PEG and Pratt?
It's a reminder to double-check with your doctor before taking the advice of a stranger on the internet.
The same can happen with many things on the internet. Reddit, Youtube etc. It's not specific to facebook.
Show HN: Tile Risers – multiplayer 2048
It's due to absorbing C02 from the air whilst in gaseous form, which is then subsequently absorbed into the blood stream after consumption.
You have the same problem on consoles I suppose, but also if companies don't invest in OpenGL or alternative frameworks, then that's another factor. I'm sure there's plenty of other warts to be fixed in Linux as far as gaming is concerned though.
There's no such thing as "US drinking water".

I live on a farm where my water source is a well. I live next to a subdivision where all the residents are on a single shared well. That subdivision is next to a city which draws its water from a local lake. That city borders another city which has a system of wells to draw from the local aquifer. In our local region is another city which draws from a large river. About 2 hours away is the city of Chicago which draws from Lake Michigan.

Each of those water systems operates independently. Each local body is responsible for determining the quality of their source and ameliorates it as needed. You can imagine that as you progress up the chain from my house to Chicago, this same process gets more and more sophisticated, but the basic process is the same.

A city the size of Flint, even with their recent financial trouble, certainly has a water department which knows what the quality of the water it's putting out is. As for culpability, whatever else you may have heard about the US, we do hold people accountable when they knowingly put the public health at risk. In fact, the article even mentions that Flint's previous mayor was ousted over this very issue.
Great list to wade through in holiday downtime. Thx for sharing.
This was a 48 hour game jam entry made with Three.js and Node. Source here: https://github.com/etodd/ld34
The way art used to work, back when it was actually good, was that artists found rich patrons to sponsor their work.

This seems like a good system to me.
No particular reason, actually, that was unnecessary. I could also just have done #(hash-map :overlap-amount ... :mid-point ...)

I believe it was an independent function initially that I just plunked in there right before setting the gist live, since I wasn't using it anywhere else, but that was back in January.
The Advanced Bash-Scripting Guide is a good resource as well: http://www.tldp.org/LDP/abs/html/abs-guide.html
Elliptics – Distributed storage for large objects with streaming support
The author + the reader?
That's Origin's weakness as well, they don't have much as far as third parties is concerned, hopefully they change that eventually, but they still make (EA) enough games to where you get a great selection. In my particular case I enjoy BioWare so I at least get their collection there, and sometimes for free, whenever they give out a game.
I guess it's worth mentioning Parkinson's law of triviality here, given it's relevant: https://en.wikipedia.org/wiki/Parkinson's_law_of_triviality
I thought this was a bizarre choice as well. The starving artist characterization is so common it's a trope at this point. But it really shows ignorance on the author's part to then select Van Gogh, who was particularly devoted to only his art and had a hardscrabble life even amongst the starving artist set.
NLP in Star Wars: The Difference Between Keywords, Topics, and Categories
This development process seems to exemplify Apple and the old-school third party ecosystem Mac ecosystem (that in part transitioned to iOS).

Where is the constant iteration to find exactly what users want?

That said, if the aim is to become a sustainable small business, rather than a billion-dollar VC funded company with no profits, maybe you don't have to get it right, maybe you can afford to be a way off the mark and still do ok?

I'm not saying that Filtron is way off the mark, but what are the chances they made exactly what users want, straight off?
Inflammation will probably turn out to be some combination of a fad and a real phenomenon that is simply a symptomatic mask for a host of different underlying issues. For example an allergy to dairy and a GI infection are different conditions but both present with inflammation.

And by the way, we don't really know why allergies develop at all. The best treatments simply tire them out, or suppress the symptoms. The immune system in general is poorly understood, so perhaps it's not surprising that people have trouble thinking past "inflammation" in general.

The idea that the human body has some pervasive fault or malfunction that can be addressed by adherence to an ascetic diet is not really new. One can find similar accounts going back hundreds of years in Western medicine, and even farther back in religions. For some reason, our minds seem to incline that way.

And it's true to some extent: obesity makes almost any disease worse, and obesity can be avoided or reduced by an ascetic diet. That is true for almost every human being, which is the highest standard that medical advice can meet.

Unfortunately, most diet advice does not meet that standard. By which I mean, it's easy to find counterexamples to most diet advice. A diet might tell you to avoid dairy, but there are millions of people who consume dairy and yet are perfectly healthy. A diet might tell you to take fish oil, but there are millions of people who never do, yet are perfectly healthy. A diet might tell you to avoid gluten, yet there are millions of perfectly healthy people who eat gluten every day. And again--I'm not talking about real allergies here, I'm talking about general diet advice.

The future seems pretty clear to me. We know that each person's genetic code is unique. We know that each person's genetic code is expressed in unique ways due to epigenetics and other factors. We know that each person has a unique collection of gut bacteria, skin bacteria, and other hangers-on.

Ultimately, if we want to create more perfect health, we will need to learn how to collect each person's unique information, tie it reliably to health outcomes, and then introduce highly personalized therapies based on that information.

The demand on information technology will be enormous. This will be a growth industry for humanity for at least the next century, I bet.
> I'll admit when fb first came out it was fun, before relatives and employers and ads came onto it. It was a way to get invited to college parties and wake up the next morning and laugh with your roomies as you scroll through pics and remember what happened the night before. It was NOT about relationship pain, being forced to announce to the whole world when something happens to you or you break up, hating other people and ways to engage in infidelity, or bragging about how many tens <snip>

Yep, this paragraph nails it. It all became serious business.
Every monetized product is designed to be addictive.
Considering how poorly current roads are maintained I don't hold out hope for anything that requires more maintenance. Many roads I drive on are not properly marked for human drivers as it is.
>> Problem is the pipes, not the river per se. When they switched water, they didn't add an anti corrosive agent

Which means there is now corrosion in a lot of old lead pipes, which means the lead will continue to get into the water for a while. IIRC at least a few months after they switched back and possibly longer.
Startup builds anti-ISIS algorithm to detect radicalisation
> Of course we all remember the days when it was hard for an artist to get attention, or even make money independently, or even get a job at all.

Wait what? This has always been the case and always will be. Art has never been profitable. The starving artist is a trope at this point.
The second Death Star was clearly a somewhat hollow sphere though.
Particularly the question of having a drink and getting your self driving car to take you home afterwards...
The Silicon Valley RDF has severely warped your brain.
Dmitry Odintsov Appointed as Chief Business Development Officer of TrueConf
The one thing I don't see is the lead levels of the water supply. Doesn't the EPA have limits on that and isn't it an easy thing to test?

It is true that different water supplies will have different levels of contaminants (lead, arsenic, etc) but can all be within EPA limits. Switching to a water supply with a higher level of contamination will increase exposure. The medical study seems to look at the percentage of children below 5g/dL before and after the switch. It goes from 2% to 4%. So with the old water supply, a certain percentage of children were already being exposed to elevated levels of lead. Switching to a water source with higher lead levels will push more children who are being exposed to lead through other sources to above the 5g/dL mark. However, this would seem to indicate that the primary source of lead for these children above 5g/dL is something other than the water.
"Because water rates are subject to public control, they are far too low and there is a huge under-investment in water." One does not necessarily follow from the other as water infrastructure can be subsidized through public investment that doesn't come strictly from billing for water.
I'm pretty sure "highway shakedowns" as you put it only happen when you are grossly disobeyed clearly posted speed limits, rolling through stop signs, or trying to squeeze through that yellow light so you can get to work two minutes sooner.
While this is true, a surprising number of games (using DirectX) run nicely under wine. It's not like 5+ years ago when many titles didn't work and those that did often had problems. Wine now runs a lot of games very nicely.

(Overwatch, unfortunately, seems to be one of the few that doesn't work at all under wine)
Simulated annealing is simple. It's just the acceptance criterion of simulated annealing that you are using.

You take the previous solution, and the current one, the difference of the cost (up or down) and plug it into the formula.

Simulated annealing allows some jumps up and jumps down, hill climbing goes only up.
Subtly attempts to frame the issue as public controlled water.

A counterpoint might be that the companies with a vested interest in privitising water supplies have lobbied to choke out the public systems of funding.

Perhaps instead of cutting deplorable tax breaks for big business, it would be more prudent to augment the public funds to prevent your citizens from getting lead poisoning?

http://www.theguardian.com/global-development/2015/jan/30/wa...
How can network errors affect the performance of your services?
I am very sorry that that happened to you and I completely understand how sometimes church counsellors can cause more problems. I was raised Catholic so believe me when I say that I understand your words about being on a destructive path of self denial.

For what it's worth, as an adult, I had to make a conscious decision not to let the assholes of my youth ruin my life.

It's bullshit that people treated you like that. I'm very sorry that that happened.
Yep, you get full dev kit hardware and SDK access for the XB1. My company is in the program.
Thats just Siemens being Siemens. Driverless trains are in no way trivial, but it has been done successfully.
What's your effective tax rate?

I'm being somewhat facetious, but there are several ways to fund local governments, including but not limited to:

A. Tax the people directly based on $ASSET (usually income, or property, or a combination of the two).
B. Lower direct taxes as well as state and federal grants, and fines from enforcement.

As someone who doesn't necessarily mind sending a few dimes on the dollar to the government, and doesn't speed often enough or at such egregious speeds that I'm subject to hyperbolic "highway shakedowns," I kind of prefer B to A because it results in a lower effective tax rate for me.
(sorry, 5ug/dL, the study listed it as 5g/dL in a few places)
I like the theory they are trying to recoup the costs of purchasing the franchise off the first movie.

Then things may calm down.
Isn't it that only Windows implementation of Kerberos is broken, not the whole
protocol?
Brilliant!

Also great response tweet: https://twitter.com/ScottWlaschin/status/676773732413808640
16 shotz
That is by far the biggest attraction for me (to use fossil). Part of me doesn't like having all those pieces combined into one tool, but after the Google Code shutdown, I've realized you can't rely on external hosting to keep your code.
Awk and perl.

I use a lot of bash though.