skysight-inc/HackerNews huggingface dataset:
Uhh... I don't believe that these concerns are valid at this point in time because the technical complexity required to actually "use CRISPR on yourself" (which isn't even a coherent idea in the first place) is extremely daunting. We're talking intermittent failure with a fully kitted lab, trained people, good protocols, and a concrete goal. CRISPR being scientifically "easy" to implement relative to the other solutions on the market doesn't mean you can just slop together some new genes and go wild. Geneticists should probably know that, but whatever.

The point is, you can't just "take CRISPR" and "chop up some cool new genes" then "use it on yourself". I mean, I shouldn't have to say this at all, but only with a childlike understanding is such a sequence of events remotely conceivable. Each of those items within quotation marks entail a deeply complicated series of planning actions and laboratory manipulations within different scientific paradigms, executed without mishap.

Even if it WAS that simple, who cares? People unambiguously have the right to experiment on themselves and alter their bodies however they wish without unwanted external interference.
EasyEngine – Managing High Traffic Sites Made Easy
VIPRE Internet Security 2016 Crack Lifetime Activator Download
Yeah, this gets really tedious though because you have to do special configuration for every vhost you want SSL on, nginx doesn't appear to offer a way to do global location directives.

Maybe I'll just write a firewall rule to redirect traffic from letsencrypt IPs over to the standalone client.
>As a test of Visual Basic skills

I would assume it's VBA. I would love to see that code.
For what it's worth, the latter does not imply the former. But your broader point stands.
I had this thought recently that inheritance was a bad solution to languages not supporting containers natively. And or a lame attempt at code reuse. (A root class is an API/Service with no versioning)
cool. thank you.
Duplicate here: https://news.ycombinator.com/item?id=10671356
They re-release it every time some company gets a crazy valuation based on a small investment.
I have Windows 7 Home Premium on my Mac via Parallels, and just I just typed in "ftp" into cmd and it came straight up.

The only packages I have installed are "Media Features" ".Net Framework 3.5.1" "Print and Document Services" "Windows Gadget Platform" "Windows Search" and XPS Services/Viewer. All of which are default features.

Which package are you even suggesting contains the ftp.exe client? Because I don't even see one. Also why would anyone go to the trouble of putting a 47 Kb binary inside of a feature package? It makes absolutely no sense at all.
What can be done with m̶a̶g̶i̶c̶ CRISPR, can be undone with CRISPR. I don't see anything really permanent here.
Thanks for the info :).
You create your own private key (or rather, the client does that for you, if you use the official one) and send them a Certificate Signing Request (CSR) which only includes your public key. The private key stays on your server.
GOTCHA gotcha.
It is not the case with letsencrypt
I listened to this one with a PhD in genetics. We both thought it was really well done and produced be he thought it was really overblown. His reasoning was that CRISPR requires a lot of tries to get right and isn't the magical gene editing tool the podcast suggests.
The more I read such stories, the more I feel Uber will rule.
Depending on your use case, you can also use ES6 features on AWS Lambda by embedding another node version in your zip package. You then use the lambda supported version of node to launch/bootstrap your chosen version when the lambda function is activated. Of course, Webpack still supports more ES6 features than node at the moment, but the gap is rapidly shrinking.
The JavaScript screen & window variables have been removed.

https://www.adblockanalytics.com/analyze.js

var abaA; if(!document.getElementById('abaA')){ abaA='N'; } else{ abaA='Y'; }
var r=new XMLHttpRequest(); r.open("POST","https://www.adblockanalytics.com/analyze/"); r.setRequestHeader("Content-type","application/x-www-form-urlencoded"); r.send("abaI="+abaI+"&abaA="+abaA);
No, and individual humans have no responsibility to the entire gene pool much as individual computer users aren't responsible for keeping the entire internet safe
I the example you link, it looks like the top half is all comments, starting with """ on a line, and ending with """ on a line. What's confusing is that code examples in the comments are surrounded by ```, and they are long enough to look like actual code.

Also, in this markup, the top comments are blue only.

Then, the actual code begins, and it is syntax-colored. In code, comments seem to be preceded by pound.

After a big chunk of code, there is another set of comments in """, and then some more code, ending with `end`.

The ``` code samples in the comments might be part of some automated comment documentation extraction standard or some markup convention. The comments near them seem very formal, defining or explaining the code.

That's the best I can do not knowing the language.
Yeah it's a nice and more importantly a safe language. I am just worried about breaking changes.
Christian Talks Online Privacy, Security and why it is important
Would that count as Prior Art come patent day ?
RSUs are actual stock. so if you get granted $100k in stock, and the stock only drops by a $1 over the course of a year, you still get $99k in stock.

less upside and less downside.
it isn't just "suck" anymore?? what did i miss?
How we talk about ambition
Second the above. The team at MS have done incredible work around the pragmatics of being able to trust the findings of the online experiment and possible areas of confounds. Anything Kohavi touches is worth paying attention to.
Yikes.

PHP's architecture is highly discussed in their mailing lists. If you have such a problem with the language, why don't you just jump in and show everyone the light?

I can't believe that you're still talking about things from 2007 or the horribly outdated fractal of bad design article. It's nearly 2016, do things not change in tech over the course of 4 years?
I thought that not being round was a error too. Now--I don't think it would have mattered. Once I saw it disassembled, and read the reviews, I couldn't see the point in buying it.

I understand they need a smart watch. Like another person pointed out, the last thing Appke wants is "Will this (any brand smart watch) work with my iPhone."

So they need a smart watch? When they figure out all the problems it might be a easier sell? Until they get to that point, I think they should work on making it waterproof.

A waterproof watch is not an easy engineering feat. Most watches, even high end watches, are not waterproof. Yes, they say they are, but unless you are vigilant on servicing a high-end watch; it will leak. I have had so many water resistant/proof watches cloud up while river rafting, or even sea kayaking.

I think Apple should focus on a truly waterproof watch. I think it would be a great selling point. It seems like it would be an easy engineering feat, but it's hard. They could do away with the crown. That would be one less gasket to worry about. And then you still need to access the internals for repair? You want customers thinking they will have this watch for life?

I think what Apple forgot about when designing the Iwatch is this; When people decide to buy a high-end watch, a little part of them is thinking, I'll have this watch for life? If it needs repair/servicing--I can easily it repaired. (If it's out of warranty it's very difficult/expensive to repair these high end watches.) "Hell, if I get tired of it, I'll sell it?" "I love those 60 year old Bubble-backs--they must be bullet proof?" "If I buy this watch, I give it to my kid eventually?"

When I look at the Iwatch, none of these thoughts come to mind. Actually, maybe Apple should have never tried to play up the luxury branding of the Iwatch. Forget about the 18k gold, and all that. Lower the pricing point. Make it truely water resistant. Maybe even waterproof?

But then again, what do I know? I do collect/repair old watches. I really wanted to like the Iwatch. Maybe the next model?
It's hard to argue, because you could pick up literally any textbook on Buddhism to see this is a fringe theory.

If you are actually curious about this topic, I would suggest you look up the importance of lineage in the Tibetan, Chinese, Vietnamese, Korean, Mongolian, and Japanese traditions. Warm hand to warm hand, as it is called, is extremely important. Lineage is legitimacy, and it's always the first line of defense against charlatans. That means that the most important thing in those actual traditions is where a practice comes from and who the teacher is (and their teacher, and theirs, etc.). It's even fair to say that the de-emphasis of lineage and tradition exists only in "Western" or "Mainstream" Buddhism.

If you're curious, Buddhist Geeks has long been far from the academic mainstream and has more recently gone much, much farther out.
> at say 1/10th atm Nitrogen would seem to work

But then you have to have a case strong enough not to bend under the pressure difference.

At 1 atm, of course, helium has much lower density (and therefore lower viscosity). Nitrogen weighs 28 g/mol; helium just 4 g/mol.
Like I said, I am only speaking for myself. I didn't claim that everyone who fits the description you just described now uses Uber.
Why React Native Is a Huge Deal
I open sourced my patent to make open WiFi more secure
It's because they've replaced Facebook as the go-to company for describing your new startup. So, instead of saying 'I'm doing Facebook for gerbils' you have 'Its like Uber for buying marmalade' and so forth...
Situation:

I install Python locally (w/o the OS-level package manager which doesn't have Python 3.5 yet) and would like to install the SciPy stack which depends on a bunch of C libraries only supplied by the Linux distro I am using.

What I'd Like:

Something like npm's package.json or pip's requirements.txt where I can declare the semantically versioned C/C++ dependencies of a project; doing conan install should fetch and install those dependencies so that pip can (as a future feature) invoke this before installing the SciPy stack and not pause a dozen times complaining about a missing dev dependency.

Does conan solve this problem ? If no, what alternatives do I have ?

Depending on OS-supplied libraries is a royal pain because they are almost always outdated.

I'm all for one idiomatic package manager per language/platform (as it is today for a lot of recent ones) which simplifies dependency management significantly.
Machine learning works spectacularly well, but mathematicians aren’t sure why
Exactly. There is a market for people who want cabs and cant get them. Uber serves that market very well in some places AND steals market share from people who would normally take a cab.
Well, there're obviously a lot of things you could improve to lower the chances of a DDoS. (E.g. introducing a TTL / maximum number of hops for a message or forwarding some messages only to some peers, thereby influencing the exact way messages are routed through the network.) But I agree it doesn't look like the most viable idea for a medium for mass communication, not even if it's just for high-latency messages. Yet, people are working on it.
Author links the Excel file in this reddit thread: https://www.reddit.com/r/Xcom/comments/3umiec/i_made_an_xcom...
I think the point he's making is that they achieved this in a much shorter time frame and they basically used cell phones to accomplish it. The companies you listed have been around for decades.
John Fogerty wasn't sued for sounding like himself, he was sued for plagiarizing a song he didn't own. Although Fogerty won and apparently eventually got his legal costs back.

"In the bizarre self-plagiarism case, Fantasy and its boss Saul Zaentz claimed that Fogerty's 1985 song Old Man Down the Road was merely his old Creedence song, Run Through the Jungle, with a new title. The label wouldn't have been able to bring the suit if Fogerty hadn't sold them the rights to his old material, something any aspiring pop star would be strenuously advised not to do in these more artist friendly days. Fogerty won the case, but then had to jump through further legal hoops to win back $1.35m dollars in costs." (http://www.theguardian.com/culture/2000/jul/11/artsfeatures3)

Let me use this to point out: I hate it when even these little fudges happen. "Unsuccessfully sued for self-plagiarism" becomes "sued for self-plagiarism" becomes "sued for sounding like himself" -- which actually means something quite different. And then that winds up the headline, people remember it and form opinions based on it. And now we've got some dumb new falsehood floating around whenever people talk about record companies and music publishing. "You can literally be sued for sounding like yourself! Media companies are monsters that want to destroy human life on earth!"

Gotta get those clicks, though. Click click click.
Swift: Highlight some of the hotness
What Do High Performing Organizations Have in Common? From MIT’s Dr. Steve Spear
> Git was not designed for security

Can you elaborate on this? While it's true that SHA-1 is now broken, my understanding is that git's reason for using SHA-1 was to ensure the integrity of the entire history.
Apple's Swift is now open source
This Country Is Going on 25 Years Without a Recession
If you're referring to their offspring, correct. That's an ethical question.

If you're using it on unwilling/unknowing participants alive today, that's criminal assault (up to murder, depending how reckless you are).
Apache2 is compatible with GNU GPLv3, though.
Once you go past the 45 drive JBOD (which costs $2000 give or take) the price per slot starts to go up quickly ... the last quote we had for the supermicro 90 drive JBOD was $9000.

So if you are optimizing for rackspace, it might make sense, but if you're keeping costs down, the 45 drive chassis is the best bet.
Yeah, and memes are tiring, but lots of people clearly enjoy them.

I really enjoy Github as a technology platform. As a social network, not so much.
I just figured that's the way it has to go if you don't want to die. I'm surprised to see other people (like my father-in-law) that eat and drink like if they were not sick.

And I like food. A lot. I'm mexican and I can eat tortillas and candies all day long. Just last year, it was not rare for me to eat ~1/2kg of corn tortillas with every meal.
"Guaranteed" is too strong a word, but I'm sure that engineering a seal that would hold reliably for years and could be mass-produced was a nontrivial problem. This is why everyone isn't already using helium.
You guys need to stop being such cynicists.
front page: https://news.ycombinator.com/item?id=10669891
>but to pass your untested experimentation along to children is a totally different ethical question.

They pass it on to the fetus, which does not have the same rights as a human even if it may eventually become such. This touches on a number of issues, include eugenics. For example, if it is wrong to pass on unknown quality genes to your children, what about passing on known bad genes? Look into the rare cases of the genetically deaf ensuring their children have the same condition, which is legal even though it would be illegal to permanently deafen a child.

Also, if a person's right to do what they want with their own body can be limited due to the rights of possible future children (who may never even happen), what does this say of issues such as abortion or birth control (especially permanent methods). We should be very careful before assigning any duties people have to persons who don't yet exist.
Didn't see the title claim in the article. They're talking about led bulbs, line-of-sight transmission and the difference between light bandwidth and radio (10K to 1).
This. I ran my first 5k race last september and I plan to run a 10k early next year.
I love everything you said, but the last sentence gave me pause.

There are a few cases were experiments on themselves using CRISPR may be at best morally "wrong". Changing your genes that may introduce defects to your offspring, for example. Another (probably less likely but more interesting to me) example is altering yourself in a way that invites a communicable disease to take hold, optionally mutate, and begin infecting others.
And now the internet and mobile apps has changed all that. Now consumers can pick the best service and simply download a different app, and the services themselves can weed out bad drivers by looking at their ratings.
But men gained only a few percent improvement with instructions...
>The number is typically calculated by annualizing a recent week, month, or quarter of the company's gross revenue, which means actual annual revenue may differ substantially.

Maybe I am reading this the wrong way but in broader context of this article it reads as they are trying to say that the actual revenue may be much lower. They should explicitly say that for a growth company like Uber, the actual revenue # would be much larger.
Wow, congratulations, that's really cool! Speaking of errors, I remember receiving the "Expression was too complex to be solved in reasonable time" error when I was first implementing Catmull-Rom splines for calculating flight paths in a game that I developed. I translated that to, "The math is making the room spin up in here." Definitely the "coolest" error I've hit working with Swift.
Agreed on everything up to the last sentence, but I would also be one to say that we should mandate vaccines and not allow bullshit objections to override public health for all.

I am not a geneticist, and I imagine the state of the art of CRISPR wouldnt even be close to something like this now, but couldnt conceptually someone create an environment in their body that causes problems with unengineered people? (and then call into question whether bioengineering yourself is actually something we should protect)

For instance, comparing what is effectively "natural engineering" of people's immune systems living in cities and close proximity decimating native populations by bringing their diseases to the new world. Their resistance allowed them to breed a whole new set of horrible things.
Apparently this is a donation that has happened unlike Mark's donations. (sorry if I state the obvious but hopefully he doesn't divorce before those donations happen (knock on wood))
The Free Tibet movement in the West has always had more to do with counterculture than the US government.

I suspect most Tibetans were rather worse off during the Cultural Revolution than in the quasi-feudal system that existed before. I'm not entirely convinced they're necessarily worse off today, but the Tibetan refugees risking their lives walking across the Himalayas into an exile where they get to "meet the Lama" couldn't really be any less focused on geopolitics...

I'm not aware of any parallel Cherokee diaspora.

I don't think the Uighurs' preferences for their own cultural practices is anything to do with them paying any attention to the US either.
PHP 7.0.0 released
HighwayJS – Fast, Lightweight Routing for JavaScript
45 drives @ 4TB, but we create 15 drive raidz3 vdevs, so we lose 3 drives per vdev ... so (45-9)*4 = 144TB.
Docker Based Nodester, Public Beta: December 10th, 2015
Cool Clojure functions (2014)
Nothing personal but your entire post reads like a conspiracy theory. How about you break down your thesis into simpler, smaller, and coherent bites?

As I'm bi, trans, and a mutualist I still don't see there being some massive underground of evil liberal (or conservative) subversives trying to kill off anyone. Even when I look at people like Ben Carson or Ted Cruz for the nonsense they spew I don't see a larger movement or moral panic going on towards LGBT people in the same respect. All I see is an over connected society seeing phantoms of old threats that are very much unlikely to reemerge in the present day or even the near future. Unpopular opinions, crappy games and other media, and the like are secure for the time being. No one of actual economic or political note are going out of their way to upset the apple cart of American society.
Why be flippant? I've simply cited resources which may be relevant to your interests. Do you have a problem with the works, or any evidence to the contrary which I may examine?
Besides from Excel and Maps which have been mentioned: Facebook because of how it used javascript. Most message boards at the time had page reloads/redirects/wait screens after posting.
This is my first encounter with it as well, but I think its a wonderful label because it accurately describes an attitude towards biotech that I find many people have in a succinct elegant way. I always found calling that group simply "anti-gmo" sort of clunky. What do you find offensive about it?

EDIT: s/strange and nonsensical/clunky/
The "severity" is often not accurate. OpenSSL recently marked an issue as lowly severe, but in fact its severity was high.

Don't trust them. OpenSSL is bad, use LibreSSL instead. OpenSSL == NSA. For sure they know weaknesses and actively exploit them if required.

EDIT: I'm talking about this advisory: https://www.openssl.org/news/secadv/20150108.txt
Positively, CocoaPods was filling a gap that should have been done at system level. So we've updated our FAQ about it, https://guides.cocoapods.org/using/faq.html
A lot of the outrage cottage industry runs on people not reading past the headline or first paragraph. If it's too outrageous to be true, it probably is.
This is no different than trusting the processor for running the emmited assembly according to the model you have for what assembly is supposed to do.

Here, the compiler emits (a subset of) javascript which are assumed to have a semantics, and we trust the browser engine to execute it according to the semantic.

Of course we don't assume the semantic of javascript to be sane, we just assume it follows the spec (and we emit accordingly).
>No. When money is earned, that money is taxed. Society has gotten its share.

So income tax is the only just form of taxation? What about consumption tax? Property tax?

> Zuckerberg is talking about donating assets that represent money in lieu of keeping it himself, which are above and beyond whatever income taxes he's already paid.

Are you saying he's donating after tax income? Or are you saying that it's like he never had income in the first place because he donated it before it became income?

>even if we accept that he should owe those taxes to society, then we have to reconcile that notion with the idea that society has chosen those charities to be considered tax exempt, and has effectively rubber stamped charitable donations as a societal good.

That's true and I'm OK with that. I was arguing against the OP's example of taxation as theft, not against the possibility of charitable giving tax deductions.
Just re-stating the obvious, but it's also interesting how GitHub has become the default go-to of repos for everyone, like Google is for - well - googling. Kudos to both GiHub and git, you are simply awesome.
The issue with something like CRISPR is that it is inheritable.

Not "inheritable and may eventually die out" inheritable, but "inheritable and all future generations from that point on would have it" inheritable. Usually, a genetic change in one organism takes a long time to spread through a population. But in this case, we have what is called a 'gene drive', where the trait can rapidly spread after a number of generations.

http://www.genetics.org/content/201/2/425.full

Any mistake will persist in the population even against selection pressure.