skysight-inc/HackerNews huggingface dataset:
> Amazingly that is untrue. Doctors have to know that it's the best drug and they often don't. Doctors are often creatures of habit. If I gave my last patient Crestor and it lowered their cholesterol, why not try the same with the next patient?

What you need is a clinical pharmacist not an advertisement. I am perhaps biased as my wife is a clinical pharmacist and one of her biggest things is to make the doctors use evidenced based practice rather than "this worked before" or "I saw this on TV".

The amazing part is despite actual studies (all readily available on pubmed etc) she gets ignored and the doctor does what he/she wants anyways. Some older male doctors (who perhaps lack some respect) will literally throw the printed out studies my wife brings to them in the trash.
My point was that the collect it all mentality is driven by the number of extremists on the list. It takes something like 20 agents to follow someone around the clock.

That means the DGSI would need 230,000 staff to follow all of the extremists all of the time
It does support some DSL modems, though.
Social housing would end the madness. In Hong Kong they merely had to announce that they were building 50,000 new units and prices plunged overnight.

New York and SF could do that tomorrow.

Raising property taxes would also help drag down the prices to saner levels and ensure that this rich source of rent ends up distributed fairly rather than coagulating in the pockets of the 0.01%.
Vox has a much more nuanced analysis of the finding:

http://www.vox.com/2015/4/1/8320937/this-26-year-old-grad-st...
Show HN: A Visual Demo of Ant Colony Optimisation in JavaScript
> In my clinic, I do not accept visits or items from drug reps (including glossy marketing materials, pens, etc); the only thing they can leave me is a copy of a peer-reviewed article.

Thank you. This is the only rational approach.
My motivation rises when people piss me off. I have something to prove, the best way I can say "fuck off" is by working hard and proving you wrong.

Telling me the truth might hurt my feeling but that is not disrespectful or rude. If I fuck up, tell me so. If you work with me, I'm not going to take your feelings into consideration when making comment's about your work. I'm going to take your experience tho. If you are new, I'll be gentle. But if you have doing this for a long time and should know better or/and like to act like you know it all, you have it coming!
Yes, both Geocode, Coherence, Ignite and Hazelcast are quit similar.Grid computation.
They don't even have to be high-end brands. Don't think I've ever bought Levi's shirts or jeans in the UK....
Technically to get HIV reproduction you need to wake up the virus, but if you are seeing more reproduction while the patient is on very effective HAART then it is not a good sign. What you want to see is a reduction in the integrated HIV (i.e. HIV DNA). Unfortunately, even with much stronger drugs this was not seen even after 8 weeks (see my main post above for the references).
What a high price!

Goes back to using Watchdog instead...
Well, the original Puritans were the Progressives of their time. Comparison across ages is always error prone.

Prohibition was both Progressive and Puritan. They're not disjoint.
Math.random() is not intended be a _good_ source of random -- it's essentially expected to be on par with C's rand(), although IIRC most implementations are better.

There are APIs for cryptographically secure random numbers, but Math.random() is not it.
Have you seen NYC? 20 stories is a small walk-up these days.

I've lived in and around NYC my entire life, and I always thought that the shape of the skyline was governed mostly by the underlying granite: lots of support for huge buildings downtown and midtown, not so much everywhere else. But in the past five years or so very tall buildings have been popping up all over. I think it won't be long until you'll have trouble finding the Empire State Building lost amongst it's bigger neighbors.
Yes of course. I would prefer if Linus made the distinction you're making by actually saying something like "respect as a programmer" But he didn't do that.

When you program something correctly, it's expected to be correct to the keystroke. Here I think we should be able to expect correct to the point of distinct idea which is not what's coming across. It's almost to the point where Linus appears as an old man from pre civil rights days about things.
A Comparison of Two Distributed Systems: Amoeba and Sprite (1991) [pdf]
Indeed. I'm not really sure why the author went with "the complexity of the web" is the real culprit. It was google, and specifically this guy's team, that was at fault. They put auto-playing sound on one of the most popular webpages in the world, and as he noted, this page never made sound before.

The rest of the article was an interesting read, but not fully taking the blame seems wrong to me.
> information about medicines

TV ads are not "information about medicines", that's just ridiculous. They are mind-games the advertisers play with potential customers in hope of squeezing more cash out of them.

You want true information? Read peer-review studies.

> Under the current model a doctor could say "You should take <x>" and I would have little to no exposure to alternatives

Right, 'cause doctors are evil like that. I just saw an ad revealing what doctors don't want me to know, I am totally going to believe it!
This is what we have in Australia. Vague ads talking about various diseases and advising you to talk to your doctor about your health problems.
>> It has also funded activist groups that oppose medication

>That's not outrageous. Medication often fucking sucks, and there's not much evidence that it works effectively. It's often better to give people techniques to live with their illness, and keep people engaged with MH services, than to just give them a depot injection every six weeks.

I know two people who absolutely cannot live without their meds and both are currently off them. One is homeless and the other is about to be homeless. Your knee-jerk reaction to the statement to which you are replying seems to indicate to me you've made up your mind about this, regardless of how much it helps or hurts.

You know how shit works in the US. Lobbyists can oppose the most sane things for completely stupid reasons. People that "oppose medication" seems to me, based on my experience, like completely stupidity. That's an extreme position. The other side (always medicate) is also extreme.
How Edward Snowden Changed Everything
I have heard this from a couple of people but I have never seen any studies to support this folk-medicine remedy for clinical depression. Do you have any literature pointers?
Lots of assertions and anger, not much substance. About the only thing I get from your comment is you have great antipathy for the people on top.
Previous discussion:

https://news.ycombinator.com/item?id=9263107
Building on this, if you do support BS3/4 be sure that the boostrap stuff is either an separate dedicated file/folder or an add-on file. Anyone who cares about those extra files should be using gulp/grunt/webpack anyways.
Mexico plans to legalized all drugs in 10 years, that definitely will put the drug war to an end.
> I am far from being a Go expert but you can see this has been written by Java developers.

The same was true of their Ruby libraries. Thanks to the auto-generation, super annoying to debug when things went sideways :)
The Rise of Alibaba Technology
Normally very smart people have an huge ego and hate politics. It's always a pity to see so much potential wasted.
Ads have always been propaganda.
Ah, yes, the "it will hurt the free markets" red herring.
This trader lost a lot of money by shorting KaloBios Pharmaceuticals Inc, which went up on the news that Martin Shkreli had taken an ownership stake in them.

You may remember Martin Shkreli having been in the news recently for a different reason: he's the hedge fund manager who bought the exclusive right to manufacture Daraprim, and raised its price from $13.50/tablet to $750/tablet, to much outrage. (Daraprim is not subject to patent, but only one manufacturer is allowed to sell it in the United States due to the combination of a small market and regulatory dysfunction at the FDA.)
Anyone with a solid understanding of investment fundamentals can distinguish an IPO which will flop versus one which will stay at or above market price on the first day.

The SEC filings from every company before their IPO contains more than enough data to evaluate their standings as a business, and are publicly viewable. There's a reason people know things, it's not all magic.
That's how it works in Oz. The drug companies tend to use their product packaging colors heavily in the ad to link the brand.
Take a look at PubSub + Google Cloud Dataflow combo.
Some ideas that will disrupt the healthcare industry
Most US domestic airlines don't use satellite links, since they're always above ground. They tend to use ground based microwave technology instead, which offers better latency.

Source: I used to do some consultancy for a provider of in-flight entertainment / wifi systems.
Must be a Rocksteady investmebt
Obviously this doesn't occur until much higher dosages are taken (unless a genetic anomaly is present, or the batch of EGCG being used is low-quality). That said, you can always take L-Tryptophan rather than 5-HTP.

Also, St. John's Wort and 5-HTP have both been clinically proven to be as effective as SSRIs in alleviating/eliminating depression. This makes them the superior choice, as their side effects are much fewer and milder.

http://examine.com/supplements/Green+Tea+Catechins/#summary1...
Open Source Mac Windows Linux Supported Local Saving Note Taking App
I don't care about the distinction between classes.

I care more about stress, how many months to go before I go broke, if I can get a job or not, or if I can keep a job, or what is my working condition, how many vacation days I get off, and so on.

How lazy are the 1%ers don't concern me.
it is most certainly regulated for usage. Widespread restrictions exist on consumption (usage) of alcohol in public places as well as within motor vehicles. It is illegal to purchase alcohol in the US if you are under 21 years of age, as it is to purchase alcohol on behalf of someone under 21 years of age; drinking is outright illegal for people under 21. Many counties around the country are "dry" counties where selling alcohol itself is entirely illegal. Regulations exist on bars as to when they can sell alcohol and when they can't, under what circumstances. Restaurants need special licenses in order to sell alcohol. All of these regulations are again in the interest of public health and the public good.

To claim that alcohol isn't regulated on usage or that most alcohol regulations are for taxation purposes only is pretty far off the mark.

The primary rationale for the taxation of alcohol itself is to counterbalance the public health issues that alcohol causes. Public health issues cost money to remediate.
Can you say more about your experience with AWS support? My experience has been consistently quite bad. I've had to resort to AWS technical support perhaps a dozen times over the last few years. They're always slow to respond (even if you have an SLA promising otherwise), and it always takes half a dozen go-rounds to get to a resolution. They will stick with you until the issue is resolved, but they don't add much value along the way. It's a slow process of "did you do obvious thing X" (even if you've already provided facts indicating that couldn't be the problem), "please provide six different pieces of information" (that don't seem to bear on the actual question), and "I've never seen this before, let me go research it".
That's why those schools all require a copy of your parents' paystubs as part of their applications.
In the days when I traveled a lot, I used IBM ThinkPad X laptops with expanded (9-cell) interchangeable batteries. You just take a spare charged battery and swap them over.

I once did London -> Chicago -> Seattle and still had about an hour of battery life for the bus from seatac. That wasn't continuous use, but as much use as I needed.
There's a difference between cryptographic security and quality. Cryptographically secure generators typically have (empirically verified) high quality from a statistical perspective, but they're not a general solution for all purposes. They're relatively slow, you can't seed them, and they don't typically have rigorous mathematical proofs of certain characteristics like equidistribution and cycle length.

The article doesn't suggest Math.random() should be cryptographically secure (although that is an option). Rather, it's a critique of the algorithm that's being used. There are better algorithms with no drawbacks that produce sequences you can safely assume have a statistically random distribution (even if the sequence is predictable and is therefore not cryptographically secure).
The Content ID juggernaut was devised by Google to placate the copyright holders and content creators whose backs YouTube had been built on. As it stands, 90%+ of all music played on YouTube is produced by the oligopoly of the three major music labels, so it is in YouTube's existential interest for the labels to be catered to. That means giving them a portion of the <10% revenue generated by the works of independent creators, and sometimes shutting down videos and channels.

YouTube is popular because it is cheap, user-friendly, and popular. And it is that way thanks to rampant copyright infringement, redeemed by Content ID and the associate policies.
An important thing to note is that of those 50,000 units being built in San Francisco, the vast majority are market rate, which are out of the price range of most people who want to live in the city. Developers are strong-armed into building a certain percentage of "affordable" units, but that's defined in relation to area median income for the city of San Francisco, which is unusually high.

Take the massive development in Hunters Point. 35% of the 12,500 units being built are affordable, but affordable is defined as less than 150% of area median income -- that's AMI for the entire city, not the impoverished Bayview neighborhood the development is being built in.

150% of AMI in San Francisco is $107,050 for one person, or $152,850 for a family of four. A new unit that's priced for someone making six figures a year doesn't really meet the common sense definition of affordable.

And with market rate housing, a lot of it is bought up as an investment property or vacation property for the ultra-wealthy, which means each new unit of housing is underutilized compared to a truly affordable unit bought by someone who lives and works in the city. If a developer builds 5,000 market rate units, that has less of a supply and demand effect than 5,000 truly affordable units, since they aren't even really the same kind of asset. Demand for market rate housing in major cities is largely driven by a need to shelter money, where truly affordable housing is driven by a need to shelter people.

This means that the statistics for San Francisco are even worse than they look, since the 50,000 units being built will be unaffordable and underutilized.
Laws never cover everything. They can't. There isn't enough storage in the world. That's why we have lawyers, judges, case law, and trials run by humans and not machinery.

That's also why hospitals and other large organizations keep legal representation on retainer: It's convenient to have someone you can ask the thorny questions without getting an IANAL disclaimer prefixed to everything.
What do you mean by "terse and verbose"?
Great detective work.

Before people go off reducing tcp_rmem too low, I thought I'd explain its actual purpose.

A TCP sender will only send data of the receiver has buffer space available. With 100msec of latency, at 1Gbit/sec there can be 12MBytes of data "on the wire". If a retransmit is necessary, you can multiply that by a number of round trips (say 2 or 3?) to get the needed amount of receive buffer to keep the sender sending. Otherwise per-connection throughput is reduced linearly with the tcp_rmem size.

I mention this because objects in a CDN are usually pretty small, and lower values of tcp_rmem may be ok for them.

And really I mention this hoping it motivates someone to fix the bug.
Adsorcery aims to circumvent ad blockers
My personal observation is that there is a lot of close, personal interaction at top tier schools. So, while this isn't entirely wrong, its missing a useful observation. Academics working in a curated environment encounter the best ideas and encounter less 'noise' from bad ideas. This isn't a problem that's easy to solve, although technology is slowly chipping away at it. Currently there's not substitute though, for being in the same room with Picketty and other smart people, which probably happened when Picketty visited MIT after the publication of Capital in the 20th Century.
The IPO Market Fails to Die
I really doubt Washington Posts' sympathies lie with poor ISIS because they lost some social media accounts. If they were condemning anyone (which they weren't), it was Pavel Durov himself, not Telegram.

This piece was about Durov's sudden 180 degree turn from "I will not censor anyone under any circumstance" to "I will have to censor some people under some circumstances, but not when it counts." It also recalls similar events at VKontakte, where he refused to give up data until he was forced to leave the country (presumably leaving VKontakte vulnerable to the government).

(Edited to clarify that I meant it was Pavel Durov as opposed to his company.)
TechCrunch Tokyo Startup Battlefield: SmartHR Takes the Top Prize
Join extreme-ish outdoor activity group.

Nothing bonds people faster and stronger than helping each other to survive in a wilderness.
About a decade ago I was thinking about spider-man swinging down a NY Avenue, his web going from building on one side to a building on the other (you know the scenes I'm talking about), and I realized it just couldn't be. Pretty quickly he'd touch the ground. Gave a good explanation to my friends and half of them didn't get it, the other half thought I was wrong/stupid because of course you can swing down an avenue like spiderman. Now I got the itch to call these same friends and tell them about these bridges. Thanks!
Insights and feedback on an Idea
Would you buy a robot that plows snow for you when it snows? Is there a market or customer for such a product? People buy the ones which vacuum and mow your lawn.

https://www.youtube.com/watch?v=S-YuFxN5nQw
This reminds me of an unfortunate part of history.

When Roosevelt signed the G.I. Bill in 1944, a lot of soldiers who returned from the war were able to claim benefits in the form of tuition assistance, low-cost mortgages and low-interest loans. Soldiers coming home from overseas had the choice of pursuing higher education, purchasing a home, or starting a business. Another result of the G.I. Bill were Levittowns, newly sprouting suburban neighborhoods offering low-cost housing to these returned soldiers ($8,000 in 1950, approximately $80,000 in 2015). With the help of the expanding auto industry and the joining of highways, people began to move out into the suburbs and build new communities.

The unfortunate bit is that while the G.I. Bill didn't advocate discrimination, it was interpreted differently for people according to their race. For example; of the 67,000 mortgages insured by the G.I. Bill, fewer than 100 were taken out by non-whites.

Now, the heavily-inflated value (example; houses in Levittown, NY are selling for approximately $350,000) of these post-WWII homes are passed down and borrowed against or leveraged to send the grandchildren of those veterans to private schools and expensive universities, while many black families struggle financially in urban sectors. The racial discrimination of WWII veterans has been cited as a reason for the increased economic inequality and racial tensions being experienced today in the United States.
Pardon my ignorance, but wouldn't higher property taxes further increase rents and housing prices? I would instinctively assume the increased costs would be passed on to buyers and tenants.
How is it a red herring with respect to political feasibility? (Which you'll note is my point; I'm not arguing anything here about the merit of the idea itself on this basis, except insofar as one counts feasibility as in-scope for merit.)
Keep your ex-lovers from your new life with Facebook’s new digital break-up-tool
MyBlockchain
My favorite lines:

The soldiers continue to battle Godzilla and the drivers motor across the bridge to safety, all oblivious to the physics errors that spared their lives.

and the parenthetical:

(I must note that the bridge featured in the movie’s climax is a cantilever bridge and therefore outside the scope of this article.)
It seems deeply unlikely to me that children of the 0.1% make up more than 5% of MIT.
To be fair, they require proof of income for financial aid, and your ability to pay for college is certainly a big factor. Most colleges (particularly the elite colleges) wouldn't want to enroll students who don't graduate.
Build effective automated testing solutions with MS Excel and Selenium
Would I buy one, if it was cheap enough.

I think it would be better to offer it as a service. I can see your customers being apartments, schools, etc. In fact, if you start calling them right now you might be able to find early adopters.
You can now blur screen shot images on Worksnaps
I think you're an unusual case. There are a ton of flights with WiFi these days.

I don't get the complaints about cost, either. They're connecting you to the world from six miles in the air. It's a pretty impressive technical feat, and $10 is a pretty reasonable cost for that. When you really need it, it's very cheap, considering. When you don't really need it, well, your cat GIFs can wait until you land.
Generally speaking, ad-hominem is best served as a side-dish. Or not at all.
Can anyone comment on Geode's non-Java support?

I'm asking because a lot of Java "big data" stuff tend to prioritize Java clients (ZooKeeper, Kafka, Hadoop HDFS, Storm, VoltDB and HBase come to mind), and while there are sometimes clients in other languages, they tend to be second-class citizens that take years to reach feature/performance parity with the Java stuff.

For example, last I checked there still wasn't a mature, feature-complete Kafka client (consumer and producer with built in offset management) for Go.
By the way, the SNES controller also uses a shift register, not a microcontroller.
>normally I block outbound RFC 1918 addresses

I'm assuming LAN traffic still works in this case.

>That is a potential problem should some rogue program on my network attempt to exploit a modem vulnerability. Maybe I'll just block all those addresses and only enable them in the firewall when I want to check the modem status.

I've been looking at scraping my modem interface for info and then blocking all but one PC from accessing the admin interface
Best time to startup in Mexico?
A billionaire targeting contrarian, underappreciated causes
Can you do this with LEDs? I thought the point was broad spectrum output more typical of incandescence.
Are there studies that there is a realistically reachable level of toxicity just by drinking tea, green or fermented? The latter study doesn't seem to say, and the former link just gives me "Forbidden".
It looks like the replacement you're talking about is actually not true. The numbers that are immigrating is declining across the board.

http://www.pewhispanic.org/2015/09/15/the-impact-of-slowing-...