skysight-inc/HackerNews huggingface dataset:
A long comment on MetaFilter by someone doing their Ph.D. research on phage biology.

http://metatalk.metafilter.com/21925/Interesting-Profiles#10...

Excerpt:

> Over the last fifteen years or so, with the breakup of the Soviet Union and the exponentially growing crisis of antibiotic resistance, phage therapy is looking very exciting again. Unlike the ‘30s, we now have a decent understanding of phage biology as well as the infrastructure to keep phages cold until use, effective diagnostic tools, and most importantly, regulatory structures that shut out hucksters. The need is also dire, for example multi-drug resistant Staph infections kill more people in the United States than AIDS does.

> Basic phage biology has also been undergoing a resurgence as we discover just how important phages are to the global ecosystem, they are indeed the dominant organism on Earth outnumbering anything else by two orders of magnitude. Indeed, despite being just ~125 nm tall (check this out for scale), if one were to stack the 1031 phages on the planet end to end you would get a tower that would stand 200 million lightyears tall. Our oceans are remarkably free of cellular life and the reason is phages, as well as the other the viruses of microbes. For example the growth and death of algae blooms are centrally mediated by viral dynamics. Meta-genomics studies of the oceans pull out more predicted phage proteins than anything else without some fancy filtering, and even then they get a bunch. Phages are also teaching us a lot about the primordial origins of life, they are after all proto-cellular organisms.

> These days are exciting times to be interested in phages.
Sure, you can write iterators in C, but nobody wants to drag all that complexity just for a reverse loop. In a language like Python of course, iterators are native and idiomatic.
Profiting unfairly from female entrepreneurs
> Another paradox is why the media always seems to portray meta studies (correlation) as fact (causation).

correlation vs. causation is a completely different axis of differentiation from meta-study vs. (direct) study, which is a completely different axis of variation from (something that isn't fact) to fact.

So, you've conflated at least three different distinctions there.
If it were as unhealthy as eating donuts (which you would need to prove), it would most likely be unhealthy by a different mechanism. So it would make sense to distinguish this if you want to find out what causes illnesses.

I also don't understand what you mean by "low quality muscle mass".
This is so stupid do they really think that terrorists care about their own privacy when they know that they are not going to come out of the attack alive.

And if they believe that they are going to catch the activity before the attack happens they are smoking crack.

They signal to noise ratio is just too high.

Plus they can always just use cash.
Gamers would disagree.
I don't know if it'd be clearer. It'd be a better representation of what actually happens but would read very strangely. `!= -1` would make a reader think "shouldn't go below 0" and only on closer inspection would you wonder what actually happens, `!= SIZE_MAX` would probably make any reader stop and scratch their head.

Whether that's a good thing is up for debate.
What you describe is how the power grid where I live is handled. That's one solution I would be more interested in than these monopolies that only seem to create horrible customer service, high fees, and poor product.

But in the end, I'm not sure what's the best way to handle it. I just know that many would agree that the current methods are not optimum, and possibly detrimental.
Show HN: PearlDB = LMDB and H2O. REST key-value database server in C
I imagine that's much of the motivation for the actual politicians, though the public wouldn't stomach this without a healthy does of FUD.
Even before Alpha, something like a VAXStation (think of the 3100 line) would have made an amazing alternative to PC.
Eh, I expected a discussion of the statistical/machine-learning concept of "cluster".
Can't one launder money by buying and running bitcoin mining? There is the question of getting it into a usefull currency again but it makes who sent money to whom untraceable.
Square jumps in market debut
You first! Seriously though, how do you chose who has to die, so that others may live?
I had Comcast when I lived in Chicago. They basically run that city. You can't get any decent internet anywhere else. All the other providers for some reason in the city, didn't cover any neighborhood I was in.

The biggest thing I liked, moving back to Iowa was decent internet provider.
How so? Does not python add some checks to see if an operation will overflow or not? Or something like that?
Each person should pay for a client SSL certificate that they use to authenticate themselves on the web.
The goal here isn't to stop what people think, but what they can do.

Extremists are not a problem, as long as none of them slip through our monitoring and control of them?

Of course the goal is to stop what people think - or would you like to make the same claim regarding racism?
This is as easy and usable by normal people as would be "web login by signing a string with your PGP key". No way.

The solution for this kind of thing is still something like OpenID, however simpler, so everyone can implement everywhere they want, even using custom SSH-OpenID servers, and normal people can use with their Google emails.
Red Hat loves containers in RHEL 7.2
This is cool! Any open source proxy that can direct HTTP traffic to one port and SSH to another?
OpenVPN supports this with the port-share option [0]

[0]: https://community.openvpn.net/openvpn/wiki/Openvpn23ManPage
I don't think it's about money laundering, which isn't even mentioned in the article. With Bitcoin, governments can't order anyone to freeze the accounts like they can with a bank. That makes it harder to prevent terrorists from accessing funds.
Listen to the presentation around the 37 minute mark. They have an IOS compatibility layer.

They claimed elsewhere in the video that Candy Crush for IOS was moved to their platform with "minimal code changes", whatever that means.
Sounds like a good idea for an open source project!
This is an instance where capitalism (and I am a capitalist) has gone awry - someone somewhere ran a PowerPoint slideshow showing they could make 'x' more dollars if they pre-emptively dosed livestock with antibiotics, and the PHB's said 'make it so'.
I don't know Telegram, but if they know that terrorists are using them, it's probably not that secure.
I'm sorry you haven't had any positive life experiences with people of religion.
Yep, that's my angle. Utilitarianism is king in epidemiology. We can pretend otherwise, but frequently our hand will be forced anyway.

I don't know if we're going to need to "sacrifice" people who have poly-drug resistant bacteria, but I'm guessing it won't be in our control anyway, if the option is between doing nothing and the patients dying versus doing everything we can and still having the patient die. Damage control is critical, and sentimentality can't get in the way.

FWIW, I wrote an in depth report on controlling poly drug resistant tuberculosis in poor countries when I was in college... the conclusion was that quarantine was not only necessary, it was the only effective course of action for people with full spectrum drug resistant TB. Of course, TB is far more infectious and lethal than garden variety "bacteria".
Perhaps provide a _Rebuttal N:_ in the relevant post as you provided this edit.
I can agree with this, but I think the hardware tokens compared to regular client certificates have the same issue: better average case (if it works it much easier to use it on multiple machines) but worse worst-case (a missing driver will completely shut you out).
The common counting down problem he's referring to is where an unsigned iterator can never be <0, so it introduces an infinite loop. Setting a found boolean does nothing to alleviate that situation.
Never underestimate the money laundering "bandwidth" of a shipping container full of cash crossing the oceans[1]

[1]http://people.exeter.ac.uk/watupman/undergrad/ron/methods%20...
Would you mind explaining "low quality muscle mass"? That doesn't seem like a real thing. Do you know how steroids typically work? They allow you to work out more and recover quicker. You're putting on "real" muscle, just faster than you could un-aided.
Might be a stupid idea, but could you use Let's Encrypt Certs as client certificates? And the browser would generate a cert on it's own?
AI Week in Review – From Tensorflow to Wit.ai and Facebook M
It could also be an endemic culture problem, where lots of people skimp on lots of tiny things to the point that the final performance goes down the drain. No one to blame, but everyone to blame.
Psychopaths are notorious for their apparent charm and charisma.

It isn't usually a good idea to hire one. They will destroy any team they work in, and if given enough power will kill any company they're employed by.
I feel like this problem is sitting on some big important concept, kind of like how topology expanded into a rich area of mathematics.
Silk and import.io: extract data from web pages into your own visualizations
Damn. We've seen a lot of new editors that mimic sublime text and then fail to do some of the most baseline, important features that make it good. Atom didn't have pane resizing for over a year (and frankly, it's just too damn slow for a smooth editor experience).

I don't hate sublime. The plugin ecosystem is mature, and you're just writing python when you do write it. Is it necessarily the easiest api or easiest to test? Naw. But sublime gets most of the basics very right, and the rest is reasonable enough.
The key sentence is here: "Management doesn't want to enforce a process because it slows everything down."

Sounds like you answered your own question, resign move on then watch that ship burn, there is a limit to how much change a person could influence.

Sorry I know it is negative to think of it this way but its really hard to find a team that follows a process you enjoy. If you love testing and think that its the right way find a team that does that, don't waste time trying to convince people with a different mind set.
I've been noticing an issue when getting bandwidth limit notifications. The same injection technique is also being used. When I attempted to filter out these messages, Comcast promptly reduced my internet speed to 1Mb. It took 3 calls over two days to realize that they were doing this as a reaction to my inability to receive the notices.
A 1997 documentary by a TV channel that didn't launch until 2002, no less!
> In the tender grades, the schools are a baby-sitting service during a period of collapse of the old-type family and during a time of extreme urbanization and urban mobility. In the junior and senior high-school grades, they are an arm of the police, providing cops and concentration camps paid for in the budget under the heading 'Board of Education'. The educational role is, by and large, to provide -- at public and parents' expense -- apprentice-training for corporations, government and the teaching profession itself, and also to train the young, as New York's Commissioner of Education has said (in the Morley case), 'to handle constructively their problems of adjustment to authority'.

> These are a few speculations of one mind. My purpose is to get people at least to begin to think in another direction, to look for an organization of education less wasteful of human resources and social wealth than what we have. In reconstructing the present system, the right principles seem to me to be the following: To make it easier for youngsters to gravitate to what suits them, and to provide many points of quitting and return. To cut down the loss of student hours in parroting and forgetting, and the loss of teacher hours in talking to the deaf. To engage more directly in the work of society, and to have useful products to show instead of stacks of examination papers. To begin to decide what should be automated and what must not be automated, and to educate for a decent society in the foreseeable future.
My understanding is that it would be use as an immunization ahead of time.
I know the book "Snow Crash" gets mentioned a lot here, but this article reminded me of Hiro and Y.T.'s stories about their different delivery jobs.
I've read plenty of gender feminist garbage like this. It is (and you are) wrong on so many points it makes my head spin. Hacker News is not the forum and there'd be no point in my expanding on it even if it were. I just wish you'd used the term "microagression" in your first post so we could all know to just safely ignore.
Gamers are a tiny fraction of consumers.
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To give you an idea, my internet options are in my area:

-Comcast (up to 100MB/s)

-Century Link DSL (up to 10MB/s)

-3G/4G modem (up to like 3MB/s)

Then 10 minutes south of where I live, that county has deals with a local ISP who behaves exactly like Comcast, but with terrible pricing and lower caps. Also no realistic alternatives.

While I could stomach the speeds of DSL (with some effort), I can't stomach the price. I'd end up paying just as much as comcast for much lower speeds. I really don't have a choice.

edit MB, not mb
By letting the government build and own the infrastructure, then lease the exploitation of it to private companies, and have other companies do the maintenance. This has its own challenges too, but at least the monopoly is in the hands of people who can be voted out.

This model was used regularly for rail and power networks in Europe, but these have all been privatised in the past few decades citing "cost reductions". The net result is that our infrastructure is deteriorating, consumer prices are rising way faster than inflation, and critical infrastructure is now in the hands of a few international power brokers (e.g. the Dutch national telephone grid is owned by Carlos Slim).
From what I've read obesity does cause heart disease but a much stronger factor in the correlation is that lack of exercise causes both obesity and heart disease.
There was no difference between the control experiment and fish exposed to parts made with FDM.

Read the article to see how FDM could become toxic/harmful, turns out it didn't.
I think you could use Keybase as reference too.
The Politician's syllogism:

https://en.wikipedia.org/wiki/Politician's_syllogism
Cash was already on its way to being banned in France: http://www.french-property.com/news/money_france/cash_paymen...
«Similarly, whatever happened to progressive enhancement?»

In one word: Frameworks.

In more words: Building HTML in two different places is typically not very DRY (Don't Repeat Yourself) and if you are assuming a lot of very dynamic content that want to update on the fly from the JS side of things all the way down to micromanaging the HTML generation at run time, well then all of your HTML building moves into JS to keep things DRY.

The hope for the future is so-called "Universal" JS (which is interesting in that its kind of circling back to the origins of JS (LiveScript Server) and ASP Classic): now that we have a somewhat standardized JS platform on the server side (NodeJS) we can use the same JS to build HTML on the server or in the client...
Bitcoin is not anonymous. Something must be done to disabuse journalists of this notion!

It's misinformation and particularly dangerous for people who need actually anonymous payments like dissidents living under oppressive regimes.
I've been thinking about this essay and reading all those comments for a few days now. I am looking for a company where people are not arrogant, and where self-confidence and outspokenness is not a proof of someone's talent, and where everyone gets a fair chance of recognition, without having to brag and show off. Those traits are not in my own personality. I am smart though. It looks like YC can be a good place for that. Unfortunately, and as I was being told personally, this kind of place is very hard to find. So all those comments makes me a bit sad, because it's basically an exception in this world. While it's good that someone speaks about JL's talents, there's actually a lot of places where someone absolutely has to show other abilities in order to be recognized.
But also a good deal easier to smuggle across borders, just saying.
Very nice. I love the "beginner hints" idea, and explicit enumeration of which cases are missing in incomplete pattern matches. Overall, the "compilers as assistants" idea seems great.
These are Telegram channels, which is a private individual broadcasting messages to others publicly (as opposed to 1-1 private messaging, which is encrypted end-to-end).

It seems perfectly reasonable that they can and will moderate channels, but not conversations.
I speak about Wahhabism, the official religious view in the whole Saudi Arabia, promoted abroad with their immense capital, so instead limiting the arguments to just "ISIS" is a major misdirection. Like that ISIS are the only one dangerous. They aren't.
At some point in Finland we got smodem. This was huge improvement. You could upload, download and chat at the same time.
https://en.m.wikipedia.org/wiki/SMODEM
The complexity is already there, iterators just help you manage it better. Even "just a reverse loop" is more complex than you might think, as evidenced by the article above.
Yeah, that's my backup plan! Thanks man
AIUI trapping on overflow is usually supported at the hardware level, so it's no overhead unless an overflow actually happens. (This is outside my area of expertise though - it's possible I'm wrong and they have to explicitly check the carry flag or some such, at least on some platforms)
As mentioned in my other comment below: channels are for broadcasting. You can create public channels. Of course a public channel will be public.

Why do you comment if you have zero information?
Yes. I orginally tried the page in a vanilla browser. What I then observed was a black page, which the game logo would then appear and then fade out. Sometimes I get a splash screen with a tip centered at the bottom of the page. Then the page would go black again. This cycle has a period of 3-5 seconds. I had never seen this behavior from a website before, so I opened up the dev tools to try to figure out what was going on. That is when I discovered the page was reloading itself. Without the dev tools, the address bar does not indicate that the page is reloading. There is no clue for a regular user what is going on other than this weird looping that does not let the user interact with anything.

I would be happy to collect more information for you, because this bug feels interesting. A dependence on google analytics scripts is something that I have never encountered before. If you are doing some kind of strange hack to get extra bandwidth out of google or getting google to do some sort of computation for you using their tracking scripts a la AWS Lambda then that might be a more interesting article for HN. PM me if there is any specific tests or information you need.

I use NoScript, and when I signed up I enabled the empireofcode.com domain for scripts. I will never enable the domain google-analytics.com to serve JavaScript.
Why would she not plead her case behind her locked door? Pass her ID under the door first, explain the situation, and THEN come out?

It seems a lot of the situation could have been avoided. I don't think they were going to shoot her through the door for a burglary.

The events after were pretty disappointing: officers not giving their names, the rude neighbor, etc. But race really seems to play a minimal role in this story and it's frustrating that she's trying to spin it as some sort of racial/police militarization issue rather than what it is: an ignorant (and potentially racist) neighbor who got her in a mess.
I wouldn't call it perfectly good. It assumes that weight should increase as the square of height when really you should be using something like the 2.6th power. That means that taller people will have a systematically higher BMI than they ought to which can be misleading when populations get taller due to better nutrition, say.
How to build an app using DCOS, Kubernetes, Kafka and more
At least when I was in Berlin this September the U-Bahn worked perfectly.
That there are people like The Rock, Hafþór Björnsson who have a high BMI but are otherwise healthy* does not take anything away from the fact that a high BMI is a pretty good indicator that you're overweight or obese. It's an imperfect measure but realistically if you're at those Obese or above levels you're either overweight and you know it, or an outlier and you know it.

* = I suspect that a good number of guys like this are taking substances that would damage them in other ways that could lead you to describe them as unhealthy, but as another commenter said that's maybe not for BMI to measure.
Nobody is going to steal your idea. If there is actual risk of this then use patents and copyright to the best of your ability.

Your startup is likely to fail if you are not shouting it from the rooftops. Only established brands are able to pull off stealth effectively.
Privacy protection hole of 29-year-old law is hard to measure
You've grossly mischaracterized my argument. I'm not sure you understood my argument. Normally I'd not reply or reply rather dryly, but given that you've taken to implying that I'm "sticking my head into the ground" and avoiding the "more important and harder to defend" question, decision, and so I'll take a moment here to answer your points individually.

I argued that they are not mutually exclusive and therefore must be balanced, which requires a decision, which is very much not sticking one's head in the ground. It is explicitly taking responsibility for any actions or decisions made from having weighed the, at times conflicting, issues / interests involved.

"Ethics as generally portrayed costs lives and increases misery in part by preventing useful studies from being done, but also though overhead from review boards."

This is an overly general statement (I'm not sure by what evidence you feel comfortable or on what basis you claim the authority to make such a claim on how ethics is generally portrayed) and not sure how you've calculate the overhead costs versus the overhead benefits (in situations where review boards prevent misery).

As to your reply, it makes a poor attempt at a "straw man" strategy, but even then lacks any evidence to support your counter-argument. You then proceed to the strategy of an "ad hominem argument", nakedly, and come across petty doing so, given the weight of the issue and the lack of seriousness with which you've treated the discussion up to that point. Finally, you've basically clumsily reworded a portion of the argument I put forth, betraying the fact that you either didn't understand my argument or are purposely trying to misconstrue my argument, while not engaging with the rest of what I put forth.

The chimpanzees are living creatures. Humans are living creature. This is an important and sober issue for many, many people. Please don't interject petty personal attacks into the conversation.
For an easy podcast production tool that can record interviews with WebRTC, check out Epishow:

https://www.epishow.com
I don't understand what exactly is a "knowledge sharing tool for teams"? Why not use Trello for that?
By definition the channels that they are blocking are public.

They offer end to end encryption, which should be as secure as reasonably possible in any communication medium.

Hopefully they will make their server code public soon so it can be reviewed. There are promises to do so, but they want to implement a federation protocol before doing so.