skysight-inc/HackerNews huggingface dataset:
mitochondrial dysfunction or dysfunction of genes related to energy metabolism

It's time to make tests for these mainstream. They're basically hidden and so many people with potentially fatal diseases like MELAS are just being thrown around medical facilities, their money being sucked out of them, and eventually either being spit out or an angel of reasoning comes in to help them out.

There's plenty of research showing varying mental illnesses having a "too much oxidative stress" or "not enough ATP" pattern to them.
Seeing how the same author has been trying to sound the alarm on political correctness at least since the beginning of this year, it seems unlikely that we'll start taking political correctness seriously any time soon.

Questioning political correctness is the realm of right-wing kooks anyway.
When iPhones reach 90%+ market share this will indeed turn into a problem. I believe they are in the 10-15% range right now.
Why Retailers Need to Pay Attention for Mobile Personalization
Why Did the ‘Twitter Revolutions’ Fail?
It's been this way just about forever in many places. I remember getting cable internet like this in college in the early 2000s, and it was pretty common knowledge that you always checked to see if the package with basic cable was cheaper rather than insisting on an internet-only subscription.
My friend who fled East Germany feels we are less free now than they were.

Propaganda is a hell of a thing.
Convertible note might be a good way to avoid Tax-liabitlies. But check with your accountant/lawyer.
Read to the end for this gem: "Under Representative McHenry’s bill, purchases would be restricted to investors who earn more than $200,000 a year or have a net worth of $1 million."

Plus, I don't think founders will really like this as it will probably find a different valuation than they thought they had, see snapchat.
Did they manage to implement folders for bookmarks in iOS version ? The Android is lacking it, which makes the bookmarks useless if you have some kind of folder management in place.
This paper was recommended to me yesterday evening, when I expressed difficulty in fully understanding section 6.9 in the PureScript book:

https://leanpub.com/purescript/read#leanpub-auto-nullary-typ...

It's certainly opening my eyes to a deeper understanding of the nature and role of the type system.
Let's not lose sight of the fact that DNSSEC purports to make client connections more secure.

Does it?

- If the server in question doesn't have DNSSEC set up: No.

- If there is a problem with one of the pieces of DNS infrastructure between the server and client: No.

- If the DNS resolver server the client is using doesn't support DNSSEC: No.

- If the client's stub resolver isn't a validating one: No.

- The user is never notified if DNSSEC is working for them or not. They can only determine this by making queries with a command-line tool, or when they get a 'could not resolve domain' error on an invalidly-configured domain.

---

Compare this to HTTPS, where the only thing the client needs to verify a secure connection is:

- The server delivering its certificate and certificate chain to the client

- The client validates the certificates

- If it isn't validated the user knows immediately.

You can go ahead and implement DNSSEC for your server, but when it comes to HTTPS connections, this does not improve user security over what we have now.
Why are we talking about this as a conspiracy to incite distrust in governments?

It's just what it says it is; "techniques for dilution, misdirection and control of an internet forum". It doesn't matter where it came from or who actually uses the techniques described.

Shouldn't the discussion be more about the effectiveness of these strategies and their repercussions?

Anyway I agree that the spelling is poor and an anonymous pastebin isn't a very authoritative source but there's still content there.

Also reading the point of view of 'paranoids' (for lack of better term) can be intriguing, see: http://stealthiswiki.tk/wiki.stealthiswiki.org/wiki/Main_Pag...

Edit: the discussion changed while I was writing this, disregard the first thing I said :P
Not only is nazi a shortening of National Socialism but it is also easy to understand when you look at how much focus there was on common effort compared to individual freedoms.

IMO calling nazis right wing is just a very effectibe play to frame liberals and conservatives as closer to Nazis.
Looked at both. ffjson is a library that generates the marshaling/unmarshaling Go code for your structs, so it doesn't support my use case at all. megajson is abandonware ("This tool is unmaintained. Please use ffjson instead").

go-codec [1] is very good, and can do things like interning string keys to reduce allocation overhead, but it's not faster than encoding/json when working on plain maps.

[1] https://github.com/ugorji/go
So excited to finally share the MATRIX with the world! We want to hear from you :)
I can see that the author put some considerable time into testing and writing the article, but nobody in the business of deploying production Posgresql should ever have been using the various models of desktop SSD that were tested. This is because the subject of which SSD are reliable has come up repeatedly on the PG mailing lists. Several heavy PG users and developers have already done testing and the universally accepted advice in that forum, for years, has been to never ever use a drive that lacks power fail protection.

Disclosure: we run Postgresql in production on Intel and Samsung "data center grade" SSDs, and I participated in the aforementioned PG mailing list discussions.

Updated: from http://www.postgresql.org/docs/9.4/static/wal-reliability.ht...

"Many solid-state drives (SSD) also have volatile write-back caches."

and this thread:
http://www.postgresql.org/message-id/533F405F.2050106@benjam...

and
https://news.ycombinator.com/item?id=6973179
The browser is not the question. The problem is the cloud sync feature.

What this has got to do with iOS? I guess people will want to use this to cloud sync their desktop Firefox?
A Steam Machine is a PC running Linux. You can do whatever you want. We're not going to do anything to get in your way or lock it down. A lot of people are going to buy it and plug it in and only run Steam. That's cool. We also think, given history, there's a pretty good chance that users are going to find something new that we have not anticipated that's going to be super awesome, that's going to make a bunch of other customers really happy. To the extent that we can add value and make that more likely to happen, that's what we're going to do.

I shed a tear of joy. A company that isn't run by soulless MBAs, about to curb-stomp a bunch of companies that are.
So, you don't trust the JS served by Mozilla but you would trust their browser? That doesn't make much sense. Firefox could be sending all of your personal data straight to Mozilla, we just tend to trust that they don't (and can verify that they don't since the source is available).
> "However, while solid-state devices are much faster they have a much shorter lifespan than hard disks before becoming unreliable, and are much more expensive"

They're still more expensive, but not by as much as they used to, and the difference is shrinking rapidly. $300 for a decent 1TB SSD vs $60-$100 for a 1TB HDD. And lifespan? Unless you're writing petabytes to them, you're going to be fine. [0] I'm far more concerned about the lifespan of my remaining HDDs.

http://techreport.com/review/27909/the-ssd-endurance-experim...

> "At the moment our simulations show data flowing at around 100mph (160kph). This sounds pretty fast, but we’d like it to be ten times faster."

What now? No, 100mph does not sound fast when talking about the speed of data.

Is there an Internet term for news articles that contain the word "could", similar to those that end in a question mark? Seems like most of them could easily add ", but most likely will not" to the end.
You answered your own question. Microsoft abused their monopoly; since neither Apple nor Google have a monopoly on mobile that set of rules does not apply.

It would require a new set of laws to have anti-trust apply to ecosystems rather than only industrial/sector/field monopolies. At the moment Apple is free to do as they please.
I would say human race lost to itself by preferring consumerism to space romantics and progress. I cannot remember a great quote from some sci-fi classic writer about it.
As significant as Apple is in the mobile market, it doesn't have anything like the control MS had of the desktop market at that time.

Using something else if is a viable option for most people that currently use Apple products, where it wasn't for many in the case of Windows back then.
No, it is a problem before that. When it becomes a problem bad enough to warrant government intervention is another question.
considering how polluted urban areas are, and how good are apples in retaining pollution in them (no sources at hand now, sorry), I would not touch those unless situation got serious.
Firefox for Android added one in the last version. I don't see why that's better than a separate QR code app, but it's there if you want it.
Couldn't this criticism be said of the grandparent as well, who lumped all of China (and other countries) together in one statement?
This reasoning just doesn't apply at all to open source software like Firefox.

I think the reason OP points this out is because the old Sync system that Firefox had was much more secure (but unusable by the general public). We know this because we could see how it worked!
Nobody uses profit when determining the appropriate fines for an individual. A court doesn't look at an offender making $100,000/year and say, well, they're only saving $5/month, so we'll only fine them $60.

If we're talking about the discrepancy between punishments for individuals and punishments for companies, then we should absolutely be looking at revenues, not profits. Or alternately, punishments for individuals should look at savings, not income.
Google Keep finally on iOS
Srs.,

Finally Google Keep on iOS a very good alternative to Evernote, it's so good that I have in fact switched all my notes do Keep. Recomend it!

http://www.techtimes.com/articles/88237/20150926/google-keep-finally-comes-to-ios-is-it-better-than-apple-notes.htm

App Store: https://www.google.com.br/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=0CB4QFjAAahUKEwjIguW7nYvJAhWCf5AKHbmZCQQ&url=https%3A%2F%2Fitunes.apple.com%2Fus%2Fapp%2Fgoogle-keep-your-thoughts%2Fid1029207872%3Fmt%3D8&usg=AFQjCNEAFWH7h6XX7eYvc9_K-_RtZCizEg&sig2=6JAJ8oIlw8FpCPe05MoWxQ&bvm=bv.107406026,d.Y2I
The wikipedia article on her is also pretty informative:

https://en.wikipedia.org/wiki/Delia_Derbyshire
> For that matter, something can taste fragrant (eg rose lemonade).

Or any whisky younger than 12 years whose name starts with "Glen".
I don't think zeveb was saying the browser was insecure, just the "Firefox account" system which may be used to synchronize/store passwords and other IID.
How to Get Any Job You Want (even If You’re Unqualified)
I'm not the kind of person who gets easily offended. Like a lot of people, I enjoy environments where people are free to hurl creative, over-the-line and asinine insults at each other so long as everybody has consented to getting their chops busted.

Having said that, there's a time and place for everything. When talking publically, it's not only considerate to refrain from mocking accents, it's wise.
I don't know about the iOS version, but in Firefox for Android a QR code reader can be accessed by tapping on the URL bar and then on the little box icon to the right.
Do You Have a Backup?
Of course, "just splice again". Why not. We can always take one of the original eggs, undo the modification, and put it back in the womb of the now 70-year old mother. And kill the 30-year old defective daughter, while you're at it.

I do hope that is not what you meant with your comment though. I prefer not to think of fellow human beings as living petri dishes, so I don't consider field-patching an acceptable solution when discussing genetic manipulation.
He presided over the sale of MySQL to sun. We, non VPs, got screwed there. 5 figures for the top developers, 7 for the vps, 8 for the CEO, and 9 for the founders!
I get KHTML (WebKit ancestor from KDE browser), but what does "like Gecko" mean? Do they add some compatibility layer to render like Gecko does?
The real solution is high assurance systems: those designed in a rigorous way with an argument that they'll remain secure against any known classes of attack. That's every layer of the stack and sideways as my proprietary framework [1] used to show. Here's an example [2] of what that's like applied to Tor. Ottela's Tinfoil Chat is only one I know that applies high assurance at the design level to eliminate risk of High Strength Attackers. He took a lot of feedback from us on Schneier's blog and applied it well.

Client-side encryption using C libraries on Linux or whatever is just asking to be hacked. Best will be secure hardware, drivers, kernel, and trusted components. See CHERI processor [4], EROS documentation [5] (esp "Principle-driven...") and Mikro-SINA VPN [6] for examples of The Right Thing in security-critical development. Need more like that.

[1] http://pastebin.com/y3PufJ0V

[2] https://www.schneier.com/blog/archives/2014/09/identifying_d...

[3] https://github.com/maqp/tfc-otp

[4] https://www.cl.cam.ac.uk/research/security/ctsrd/cheri/

[5] http://eros-os.org/eros.html

[6] http://genode-labs.com/publications/mikro-sina-2005.pdf
Comcast has a lower tier internet service that most of their sales people will not even mention.
Why Quality Content Means Everything
Very interesting! But I don't quite see why you need to bother with tracking pieces and swapping them. Can't you just go by the convention that pawn 0 is the first pawn you find when scanning across from a1 to h8, pawn 1 is the second pawn, etc.? Similarly for the knights, bishops, and rooks? (obviously still using the fallback when necessary)

That would eliminate the need for computing swaps while still producing the same move code for a given move in a given position.
Yelp's open sources its PaaSTA platform, powered by Mesos and Marathon
Why we need to create careers for research software engineers
If the government gets to carried away with this, then jury nullification https://en.wikipedia.org/wiki/Jury_nullification will come into play.
Stack Overflow – Serving Programmers Even Better
I'm stationed on Oahu and was extremely surprised to find Oceanic Time Warner's Internet-only packages were one of the few affordable things on the island. Not looking forward to moving back to the mainland and dealing with another cable company.
The JS that Mozilla serves (and the server that gets the reply) is potentially under control of the US government.

Trust of Mozilla has got nothing to do with it. It shouldn't even be a requirement.
As others noted, this applies to all "Cloud" accounts, so:

"Of note, your Dropbox, Google, Microsoft, Yahoo accounts are not secure, because JavaScript"
Where should I host my single page app?
From evolutionary biologist and MacArthur Fellow David Hillis[1]:

Species are exactly as real, and as unreal, as rivers, for many of the same reasons. It is true that every river (species) is different, and it is hard to describe their boundaries, and their beginning and ending points are often unclear. Also, there are some arbitrary aspects about rivers, like when we call them a river or a stream, or how we divide and name segments of a river.

When two rivers merge into one (or one species splits into two), it is very hard to determine exactly when that happens. Yet, it does happen, and it is pretty easy to see after the fact (but not in the close details of water molecules or individual genes at the point of merger). But the concept of a river is very useful, and I have floated down many rivers that seemed pretty real to me. I also regularly encounter and interact with a lot of species that seem quite real to me. All of these difficult attributes I mentioned are true of all historical lineages: species, countries, corporations, rivers, families, or almost anything to which we assign a proper name (or could).

Yet, why are biologists perplexed about species? Clearly, life is not distributed continuously, but into lineages of historically related individuals that share a common reproductive (or sometimes, ecological) boundary. I just can't see how one can make any sense out of life without understanding and accepting the reality of species. It would be like trying to understand the economy while denying the reality of corporations, or global politics while denying the reality of countries.

[1] https://en.wikipedia.org/wiki/David_Hillis
I imagine you're probably still subsidising the sports watchers though.

All of these companies use sports as a major buying motivator, like in the UK Sky basically went mad on buying every sport they could. I would assume the extra subscription alone doesn't cover the high licensing prices they pay, so they spread out the cost to all the other consumers too but just charge a bit extra to the sports fans.
What would be the point? There are a great many QR apps out there that can call your configured preferred browser when appropriate (assuming Apple allows you to set a preferred browser that isn't their's - I don't have nay iDevices so can't test this personally). QR codes can contain data other than URLs for browsers to follow (though you would be forgiven for thinking otherwise given that in the vast majority of cases this is what they are used to transmit) so it makes more sense to have a QR app that deals with QR codes generally and defers to a browser when a relevant URI is detected.
Of course I meant, the next generation need not be split into two types of human. The next generation can change again. The point of genetic modification is, that the next generation doesn't have to exactly resemble the one before. So the straw-man of 'what if they can't interbreed' is moot.
Are you sure? This dates to a year ago: https://whispersystems.org/blog/whatsapp/
The thing is Apple doesn't have a monopoly on the mobile market, specially when the worldwide market share is taken into account.

Until then, Apple is free to control 100% what comes into their platform.

The same way any other vendor is free to do (e.g. games consoles), when not covered by monopoly laws.

When they reach a size that falls into what the law considers a monopoly, then the game changes, as they have increased responsibilities towards the market.
I really thought this was going to be some obscure implementation of Quicksort.
> Additionally only Apple's JavaScript engine is allowed to use a JIT compiler.

Can you elaborate? I was under the impression that as of iOS 8, if a developer implements WKWebView in place of UIWebView they would have access to Nitro.
Show HN: HireGun for finding marketing consultants/agencies
No, it's more that Denver sucked. A57 is just faster.
That planner was superior and prior Prolog.
Custom pattern-matching and advanced macrology
Sure, the parents will have influence. And they will get their information from the culture -- lamarckian evolution, if you want.

(Edit: One thing everyone do seem to agree on -- humans are hard wired genetically to get most of our behaviour from culture.)

In vivo means "In the living body". The 2nd and 3rd paragraphs were about what could be done if it was hard to modify existing bodies. (Sorry if I was unclear.)

About modifying the genome safely at all -- see the Iceland project.
Oh my mistake. Thanks for clarifying.

So in that case, how would you securely sync your data using Firefox?
DNSSEC and DNSCurve are completely different matters.

As far as I understand (I may be wrong!):

1. DNSCurve establishes an encrypted and, optionally, authenticated channel between you and upstream nameserver. It doesn't do anything about the data that is served over that channel.

2. DNSSEC protects the integrity of the data that is served by authoritative nameserver (and redistributed further) from some rogue adversaries (except for registries).

About DNSCurve - you should ask your upstream nameserver provider (usually, an ISP) to support it. Although everyone running a nameserver should do so. But it's purpose is completely different from DNSSEC is about - even though the latter's concept is flawed.
Great rant, but I always thought it was pretty ironic because I'm not aware of a development environment that requires you to track more shit in your head than Node.js and JavaScript.

Maintaining other people's JavaScript is easily the most frustrating and inefficient development that I ever have to trudge through due to the ceaselessly shifting landscape of Node packages and best practices (Grunt, Gulp, Webpack, Backbone, Angular, React, callbacks, promises, await, etc...) and the utter incapability of development tooling to assist due to JavaScript's dynamic typing.
All good choices. I'm glad they tried at least. I'm not sure about France but in U.S. universities are expected to give people the job skills they need. Pascal might be easy to learn with and Scheme might be more ideal. Yet, most jobs were using Java or C++ so many schools switched to using those. People start from day 1 thinking that's how programming and design are supposed to work. Kind of sad.

I'm not arguing universities should be impractical. I just encourage them to teach both what's beneficial to the mind and quality of our industry plus the practical tech. Increases odds good things will spill-over from one to the other.
Because QR is dead and nobody wants to pretend it isn't.
The "Eskimos have hundreds of words for snow" is actually bad linguistics--for pointers, see Mark Liberman's post on Language Log (http://itre.cis.upenn.edu/~myl/languagelog/archives/003286.h...).
Look up direction and traffic duration via command prompt (Nodejs)
> rather than classifying it as "all in the mind" as the PACE trail was seemingly intended.

It's intensely frustrating that ME sufferers dismiss psychiatric illness as "all in the mind". It's hateful, ignorant, stigmatising, and stupid.

Obsessive Compulsive Disorder is "all in the mind", yet it's listed by world health organisation as one of the ten most debilitating illnesses.

By pushing this "it's not in my head" bullshit ME sufferers make it harder for people to get evidence based treatment.

You're wrong about PACE too. http://www.ncbi.nlm.nih.gov/pubmed/26521770
> On what basis have you arrived to those conclusions? The normal diet in China and Indonesia is plant based. Yes, they eat a lot of rice, but that rice is much more healthy than the vitamin-fortified substance made out of bleached, white flower that we call bread nowadays.

Likewise, I'd ask you what data you used to arrive at your conclusion that rice is healthier for you than bread? A quick googling of white rice vs white bread told me the exact opposite, or at best, that they were relatively equal. Other colors compared similarly, assuming I kept them similar. The terms "rice" and "bread" are way too generic to compare, really.
Did you ever like mozilla, or were these reasons more recent in nature?

I personally liked Mozilla up to the SJW/Eich situation. Since then, every move they've made has been counter to the tenets of free software that JWZ and team instilled. Now, I merely use it because everything else is less-free.

I'm hoping Servo will end up being to Firefox what Phoenix/Firebird/Firefox was to Netscape.
But are you considering opening this up?
My wife and I watch Netflix when we do watch anything (we have twin two year olds, so this is a rare luxury). For some reason or other we turned on 'regular' tv the other day and there was an NFL game on. We could not believe how many commercials there were! Also, just how insultingly unintelligent they were. I mean, who actually would want to watch these commercials!?
Why not allow competition in software?
This is true, but what pjmpl was saying is that Mozilla couldn’t port their JITted JS engine to iOS and expect it to get through the app store review – they have to use Apple’s.