skysight-inc/HackerNews huggingface dataset:
I, too, have thought about conducting a pseudo-double-blind experiment on myself. I think I could pull it off, but I'd also be willing to pay a third party to help me. For example, DoubleBlinded could partner with a respect supplement maker, and offer personal experiments in any supplement made by their partner. The consumer wouldn't have to worry about setting up the experiment correctly, and they would get their own results immediately upon completion. Aggregate studies can wait until enough customers have self-experimented on the same supplement, and DoubleBlinded can afford to wait that long, because the partnership model keeps their costs low.
tlsinterposer[0] helps in cases like this. (tldr: LD_PRELOAD middleware to upgrade an application's OpenSSL support without modifying the application.)

[0] https://github.com/Netfuture/tlsinterposer
But that would be bad English. I wouldn't expect the Nature editors to let such bad English slip through in an important title, but I admit it is frustratingly common to see people not caring too much about that sort of thing.

I had the same concern as GP. I don't understand the title; the controls seem not to have fungi in their brain, which had always been my assumption about, for example, my brain.
I trust Seymour Hersh on this.

If my only choices are either believing what the government says, or believing what a decorated investigative journalist says, I'm going with the investigative journalist. The government simply has too much of an incentive to lie about something like this.
Goldman, JPMorgan Said to Fire 30 Analysts for Cheating on Tests
> You can't write Java enterprise software in Go, and I really appreciate that.

You can, and I've seen it, unfortunately.
Unminified via http://unminify.com/

http://pastebin.com/Y7Q5H0AL
Why would you expect all of your money back? On top of the wasted kit, there's shipping, handling etc. You are of course allowed to withdraw from your decision, but it's unreasonable to expect the other party to fully cover the cost of you changing your mind.
Interestingly, ALGOL failed because it was too complicated to implement.. And Djikstra played a huge role in the formulation of that language.

Why aren't you using ALGOL?
"Running arbs" is fine and definitely creates value. The problem with vampire squids is their parasitic relationship with govt, i.e. the people with the guns.
Assembling Haskell programs from network fragments
AFAICT, there isn't a control group. You have 4 weeks of pills and each week it could be real or fake. So you are comparing against yourself.
Schizophrenia is an interesting one showing a very high correlation with antibodies for a retrovirus called HERV-W which became part of the DNA of our pre-human ancestors about 60 million years ago and which has been passed down ever since.

http://discovermagazine.com/2010/jun/03-the-insanity-virus
I don't think you quite understanding how institutionalized statecraft works. Think of it in this way "Pakistan knew where OBL was and told the US - for what gain?"
The link between Al Qaeda and 9/11 is an actual link, not a 'link' nor was it made solely or even primarily on the basis of the passport. If the passport hadn't been found, we'd still know who was responsible for the attack.
I tried this for a while in MLB but came to the conclusion that rake + irreducible variance made it pretty unattractive. Not sure about other sports. Apparently the real key was knowing all the other players lineups in MTT formats, according to recent stories.
CuriOS: Improving Reliability Through Operating System Structure (2008) [pdf]
This would never happen because nukes. Pakistan has 100+ nuclear warheads - the day they fall into the hands of terrorists is the day we're all toast. No one is ever going to embargo Pakistan completely even if their leaders are openly sponsoring terror - what's going to happen at worst is forced regime change.
On the one hand, it makes sense to have registries of vehicles passing through public spaces, for the sake of contract law and liability; on the other hand, is there any human activity that the US government will not want to monitor, control, rule, or otherwise restrict?
I agree. _this_should_be_underlined_
I don't have much to add, other than I went to the talk this past Wednesday (Python meetup in SF) and really enjoyed it. You did a great job. I agree with the currently-most upvoted comment here that I really value these kinds of war stories. Making technology choices is a huge part of what I have to do on a week to week basis and it was great to hear your experience.
Data Visualization: The Most Successful Labels in Hip-Hop
Never start by saying "So".
At the minimum they'd have to change their name and probably do a huge down round if they need to raise more money.. Also, is the CEO really going to want to run a traditional lab that has little competitive advantage over their competitors? Doesn't really fit into her ideal of making the world a better place. Are any of the board members going to want to stay on and take responsibility for this train wreck? People like Kissinger, Schultz, etc have everything to lose and little to gain from being on the boards of controversial companies. They are mostly concerned about their brand and legacy above all else. I don't think it looks good for them
Congratulations!

Also thanks for the way you managed the project. Ansible was the first big, well known Open Source project that I contributed to, and it was in great part due to the effort you put in welcoming everybody in the IRC channel and mailing list.

Well done!
I miss the time when you bragged about increasing performance without resulting in having to switch frameworks or languages.
I'm not sure I know how to feel about the fact that the author had to explain what a Light Pen was. Why am I so old?!
Continuing your thought experiment, why stop at people with a high paying job offer? What would be wrong with allowing anyone to move anywhere and stay as long as they please, provided that they pay their taxes and don't break any laws.

To put it in perspective, I've never heard anyone complain about people from other states moving to California and taking jobs from people who were born here, so why should we be so concerned about people moving from other countries?
New Research on a Good Night’s Sleep
I haven't had much crypto-in-practice background (outside of thought experiments), but I have some math background so I'm quite curious. Shouldn't people also be worried about non brute force attacks based on finding mathematical solutions? I mean, "The Uneasy Relationship Between Mathematics and Cryptography"[0]?

[0] http://www.ams.org/notices/200708/tx070800972p.pdf
Non-paywall link:

https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=newss...
Since there were jokes further up, this reminded me of another one:

A delegation of Japanese visits the GDR and of course is shown many important companies and places. At the end, they are asked "What did you enjoy the most?"

"The three great museums: Pergamon, Pentacon and Robotron"
>Surely I can't be the only one that finds this experience cumbersome?

No, not just you. I consider myself a newbie on the board and often have to look at the "time" the comment was posted to see it is new.

FWIW, Here is what is on my Wishlist/what I hope the future holds for HN.. Eh, the audacity of me but here we go;

1) Just like how a new person is shown in a "green color", maybe new comments can be given a color also so once a user reads it under their profile it can change to the regular color. That way, it is easier to know what is new on a thread.

2)Every user based on rank should be assigned a color. To change a color in addition to karma points. This particular idea of rank I got from myfico forum as I contribute over there and it makes things very competitive although it is a different kind of board. Their version of "karma" is kudos. Here is an example of people with different titles and colors - http://ficoforums.myfico.com/t5/Credit-Cards/bd-p/creditcard FWIW, I am user Yes-Its-Me on that board.
Some thoughts:

Why did you pick a modp group instead of an EC group?

Why doesn't Bob send y? Y is derivable from what Bob sends. (Your zero knowledge claim is at least a bit wrong, since Bob is sending correlated numbers and, in fact, y can be derived from them.)

Bob's sent values can be rewritten as y2^b, y2^c, and y^-1 * f_1 * f_2, which makes me wonder why f_3 is sent.

Why does Bob prove knowledge of x+b+c? Can you clarify the spoofing attack?

What prevents double spending if the tracker is malicious?
Most of what he's writing about, and much more, is made substantially easier with systemd timers.

E.g. want errors to cause e-mails, but everything else to just go to logs? Use a timer to activate a service, and make systemd activate another service on failure.

Want to avoid double execution? That's the default (timers are usually used to activate another unit, as long as that unit doesn't start something that doubleforks, it won't get activated twice).

(Some) protection against thundering herd is built in: You specify the level of accuracy (default 1m), and each machine on boot will randomly select a number of seconds to offset all timers on that host with. You can set this per timer or for the entire host.

And if you're using fleet, you can use fleet to automatically re-schedule cluster-wide jobs if a machine fails.

And the journal will capture all the output and timestamp it.

systemctl list-timers will show you which timers are scheduled, when they're scheduled to run next, how long is left until then, when they ran last, how long that is ago:

$ systemctl list-timers
NEXT LEFT LAST PASSED UNIT
Sat 2015-10-17 01:30:15 UTC 51s left Sat 2015-10-17 01:29:15 UTC 8s ago motdgen.timer
Sat 2015-10-17 12:00:34 UTC 10h left Sat 2015-10-17 00:00:33 UTC 1h 28min ago rkt-gc.timer
Sun 2015-10-18 00:00:00 UTC 22h left Sat 2015-10-17 00:00:00 UTC 1h 29min ago logrotate.timer
Sun 2015-10-18 00:15:26 UTC 22h left Sat 2015-10-17 00:15:26 UTC 1h 13min ago systemd-tmpfiles-clean.timer

And the timer specification itself is extremely flexible. E.g. you can schedule a timer to run x seconds after a specific unit was activated, or x seconds after boot, or x seconds after the timer itself fired, or x seconds after another unit was deactivated. Or combinations.
I agree, he did go through a slump, but I recently listened to The Peripheral as an audio book, and it was excellent!

His early books really set high standards for distopian scifi.
Yes, all of them: https://news.ycombinator.com/item?id=10403039
It sounds like you're the intolerant one.
Dupe: https://news.ycombinator.com/item?id=10397149
So do I! Eventually you 'top-out' in a language/framework though... and then its all tears.
The downside is you have to renew it every year. Costly if the lawyer does it and too much waste of time.

With E2, you get it for 5 years and no more paperwork every year. Then you renew it for another 5 years.
You think what's reckless? The guy who wrote the article has a degree in Electrical Engineering and the article's great.

EMF is not a force and it's not the only thing the word electricity refers to. I've just checked a physics and an electrical engineering textbook and neither refer to electricity or EMF the way you are. I honestly don't know where you're getting these ideas.

In physics there is a fundamental force sosmetimes called The Electromagnetic Force, and in a sense it does describe all of electricity, but it's not the same thing as The Electromotive Force.
> The notion that women are more dangerous is a commonly spread mysoginist lie. It's designed to get upvoted by other anti-feminist, anti-woman "men".

[citation needed] on that wild and extremely inflammatory claim... You like sources, don't you?
The top comment in this thread is pretty accurate. Most founders (YC and other) I know came on a visa waiver originally, and moved to an O1 visa to stay long term.
This is patently absurd. It's mind boggling that people still hop on here and declare how something is "amazing" or "horrible" for a particular problem-set as fact.

You want my anecdote? Go is brilliant for web services. We've decreased server costs significantly while decreasing response times by orders of magnitude for write-heavy APIs. Concurrency primitives that do bleed into parallelism have made a mockery of interpreted dynamic languages.

But don't believe me. Ask Cloudflare, or Google, or Dropbox, or any other number of companies how horrible Go has been.

But just for shits and grins, I'll bet it'd take me moments to find people in situations where Go didn't meet their needs or domain requirements.

Please stop with the absolutes. They're absolutely ridiculous.
>clamouring of families trying to get their hands on anti-fungal drugs in the future in the hope that it helps their loved ones but we simply won't know if this will help until there's more data.

It may not be so hard to get data - try anti-fungals and see if the patients get better. There are plenty of patients and the drugs could be tried in countries other than the US. It could be possible to get data in a few weeks rather than years of trials.

There seem to be about a dozen anti-fungals at the moment which could be tried. Presumably the best choice would depend on which fungi was involved. http://www.ncbi.nlm.nih.gov/pubmed/17381184
yes id guess the no computer and tv helps with the stress levels, rather than being "because of looking at the screen" by itself.
I bet if they double stain with anti-amyloid-Beta they will see the staining overlap. They just say they used "antibody raised against proteins obtained from C. glabrata, C. famata, C. albicans, P. betae and S. racemosum", so they don't even know (or want to say) what these antibodies react with...

Amyloids have generic secondary structure (can be created from any amino acid sequence under the right conditions) and yeast produce amyloids. They quite possibly raised antibodies towards yeast amyloids and then stained human amyloids. It is strange they do not report staining these brains for amyloid-Beta, it is an obvious thing to do.
Under federal regulations, the lab that does the sequencing is apparently required to keep their results for 2 years.

[42 CFR § 493.1105]: https://www.law.cornell.edu/cfr/text/42/493.1105
Yep, the U880 was made at the VEB Mikroelektronik „Karl Marx“ in Erfurt. After the reunification parts of the VEB were converted to a company that still runs a semiconductor fab there (X-Fab).
Were they so far behind in VLSI design that decapping and reverse engineering was a better option than re-implementing the processor from a published spec?
How does this handle files that are gigs in size? It looks to me like you load the entire file into memory and pass it along, shuffled.
That's a fun (and scary) thought. Thankfully we're not there yet. When we do get there I hope we'll have the same privacy concerns as we do today for these online databases.

It doesn't invalidate the current concerns, though.
Following links on the RMS article here, I find he's made a suggestion for online content sharing payment quite similar to one I'd independently arrived at. Also Paul Hunt's (Pirate Party UK) broadband tax proposal.

Seems a good idea whose time may well come.

https://www.reddit.com/r/dredmorbius/comments/3p0bp6/richard...
After reflecting I am wondering if this is a result of the natural tendency of scientists to avoid any hint of overstating their work. Were the fungal infections all in the same region or by the same fungus it'd be absolutely shocking. It'd be a "cold fusion" level revolution for the field - and a "cold fusion" level embarrassment for them if they are wrong. So they are extremely keen to put up front that the picture is not nearly so clear as that.

There is also a tendency when scientists are extremely confident they have found something incredibly important to understate it. I always think of the Watson and Crick "It has not escaped our notice ..." statement in this context.

This is all based on guesswork though, so that's why I'm curious about what people in the field think.
I meet Andre the Giant when I was 9 years old. He actually talked with me and my dad for a few minutes and shook my hand. Was really nice with the biggest hands I ever saw.

P.S. I like Pro Wrestling for like 3 months and than hated it. I met him right when I was liking it. :)
Fair, but surely Twitter itself bears some responsibility for having decided to go public in the first place? (Or, if you believe the rumors, for having taken on enough investors to have been forced to go public.)

We should keep in mind that the bankers got their mitts in the oven because Twitter opened the oven door.
So, after reading all of the comments and some of the links and not being a lawyer, nor YC founder and residing outside of the US and just been there once on B1...

The plan:

* get to the US first on B1, quite easy to get and relatively applicable for YC

* while there, set up a US company and open a branch in your own country and make it to employ you officially

* continue to investigate your options and if young file for J1 (internship) or if older file for O1 (achievements) with references from other founders/VCs

* don't mess with H1B

* worst case scenario if you didn't apply for other kinds of VISA - leave the US and come back periodically on B1 if need be and continue to be employed in your home country by a branch of your company in the US. after a year or so apply for L1 (inter-company transfer) which is almost automatic to get and allows the spouse to work too.
You should quit.
OK, poorly worded. He started in politics early. However, did have a long career in business as the CEO of Searle. It shouldn't be surprising that he was on the board of directors of another biotech.
It's kind of amusing that so many in Silicon Valley rail against Wall Street and "financial engineering" when the biggest "winners" of this tech boom are products of Wall Street and "financial engineering."
That incurs a lot of R&D costs and costs of installation, and people might not be okay with such a thing happening because it affects everyone. On the other hand, querying a DNA database doesn’t face much resistance because it only affects a small number of people.
im not sure if they rely on it i think its just part of the money that comes in. Totally weird but sometimes I wonder if enforcing by law that you can't get more than x% profit margins else you redistribute to the govt would actually fix the whole capitalism/corporate issue.

Of course this means the govt has to be controlled better - but thats an easier target than "all corporations"
Blood, Simpler (2014)
RMS typically calls out an leading exemplar of a specific problem. In the case of eBooks, that would be Amazon.

And yes, he does offer specific technical alternatives.

Amazon's been large enough to exert its will on publishers before.

http://www.antipope.org/charlie/blog-static/2014/05/amazon-m...
Methylene Blue has shown promise as an alzheimer's treatment. It's a potent antifungal. It easily diffuses through the blood brain barrier. It also happens to be cheap and unpatentable.
Equaldex: a collaborative LGBT knowledge base
Ask HN: What are soft skills?
> I wouldn't consider Bin Laden to be a Muslim

He wasn't a Scotsman, either.
New reality show
I assume you've seen this. http://micro.magnet.fsu.edu/creatures/pages/russians.html
If you have an unknown input size and a finite number of requested output lines, you can still do it in O(n) and no additional memory, by having a steadily-decreasing chance of replacing one of the outputs with the next line.
Haven't we studied the effects of Alzheimers enough not to need the control group? I worked in clinical trials and one study still haunts me knowing what happened to the control group.
With ads
ALGOL-60 saw fine use in its day; Dijkstra criticized ALGOL-68, which indeed failed because it was too complicated to implement.
There are a number of rough spots to the UX here. I tend to assume that pg didn't care enough to add it and the current staff either don't have the time or the inclination.

Although being able to sort a thread by latest comments shouldn't be impossible in an application written in the Language of the Gods, but it might be more difficult than anyone working on the site thinks it's worth. I understand their reticence towards new features but not all added complexity is a sign of feature creep. They are (at some point) adding at least a mobile friendly layout and thread folding so maybe resorting or indicating new comments might be in the pipeline too. If not, just adding proper timestamps to the comments somewhere (even just as data attributes) would make it easier for people to do it themselves through scripting.

Also, since the staff doesn't particularly like meta discussion this thread is probably going to be sunk by the moderators pretty quickly.
https://www.google.com/search?q=soft+skills&oq=soft+skills&a...
SmileBASIC 3 is out; first impressions
New editor is fantastic! Search and replace, highlighting, copy & paste, in-editor help, and auto-edit on your line in-error. This is actually a viable way to edit something in portable fashion.
Crucial note: This piece is written by Mike Mortiz of Sequoia. It appears to be in tandem with his recent appearance on Bloomberg News (http://www.bloomberg.com/news/articles/2015-10-17/sequoia-s-...)
I use SaltStack masterless extensively. It works very well. It's not an after thought and numerous salt contributors use salt in a masterless setup.
Learn about it at http://smilebasic.com/
I'm using it on the New 3DS.
I have to note this, because I think it deserves quite a bit more attention.

SSL is extremely expensive, on RAM (perhaps the implementations have optimized for throughput over RAM). I have yet to benchmark any SSL implementation in any language, with any binding, that can use less than 20kb per SSL connection. I mentioned in my talk here that SSL is very expensive, here's my benchmark suite that others may add to:
https://github.com/bbangert/ssl-ram-testing/

I have implementations in several languages, so far both Go and Python 3.4 can get as low as the 20kb cited. If you can get your per-connection state below 20kb, then merely adding SSL means doubling or worse your RAM requirements, which is huge.

I appreciate that everyone loves obsessing on the language wars, but the SSL RAM overhead affects us regardless of language. I covered that in one of the slides near the end, it'd be great to see some movement on reducing the RAM footprint here.
What does it mean to be anti-feminist without being anti-women? What sort of beliefs would you have?
So, turns out there's many types of fungus that affect behavior, and there are even a few that create entirely new behaviors. One such example is ants, when infected by a type of fungus, will climb high and latch onto a branch by biting hard into it. This is so that the ant will get eaten by birds, which then complete the life cycle of that fungus.

There's not many well understood systems (the other well-studied one is toxoplasmosis and cats), but one researcher on Experiment, Charissa de Bekker, just released a new paper with findings from her project.

The results gave a first clue about the many genes that are involved in this manipulated biting behavior. For instance, that the fungus is likely producing LSD-like compounds and is secreting proteins that could affect serotonin and dopamine levels in the brain, as well as the ant’s ability to communicate through chemosignals with their nest mates. As well, in the paper, they release the entire transcriptome taken from the brains of these ants, giving other scientists a chance to use this as a model system and to begin to target which genes go on to influence behavior.

I was just talking to her about it this week, and so this news is very timely and a bit eerie. But very cool.

http://www.biomedcentral.com/content/pdf/s12864-015-1812-x.p...