skysight-inc/HackerNews huggingface dataset:
Perhaps you are basing this on the incorrect premise that Alzheimer's is understood at all. It isn't, and worse essentially no progress has been understanding it for many years. For example, the purpose of APP (amyloid precursor protein) remains mysterious. The same speculations are thrown around now as by the guy who discovered it in the 1980s.

At some point you need to start considering that something is seriously wrong with the research methods or theories. This fungal idea is good to explore, but the evidence provided here is not convincing at all.
No but it's been an income market allowing you to provide for your family.

I have nothing against progress, lets just not claim that it's somehow better for the drivers.

For us as consumers sure, but not for the drivers.
Being a Ruby to Go to Elixir convert myself, I can only second this. Elixir is a really great language.
I was not familiar with Chafee prior to the debate and I liked some of the things he said, but he really did blow the Glass-Steagall question very badly. You don't get to be President by making excuses. He should simply have said "It was a mistake. I did not educate myself properly on the issue before voting, and I regret it." I think everyone would have been fine with that.
Crazy or Brilliant? Commuting from Las Vegas to San Francisco to Save Rent
Chevrolet Volt Review: It's Incredibly Improved
> I'm going to talk about some stuff which struck me while learning Haskell. This post is meant for people who write code in languages that are not Haskell, but would like to learn more about the experience of learning it. Like many of my posts, it's for past versions of myself.

It's baffling to me that people find the first two weeks of language experience so interesting. Every language, even incredibly productive ones, have idiosyncrasies that get you in the beginning.

Lets instead talk about how A compares to B after 6-9 months with similar sized teams. Lets talk about on-boarding new hires once the organization has built a skilled team in that environment.
Hi There, I built this app to help me with a major travel project I'm working on to convert a used school bus into an RV and drive it around the US and into Central America. But it occurred to me that it would have saved me some headache on previous trips. So it made sense to offer it to others who may also need it.
1. You're confusing the author's position with my own. I don't claim (and frankly don't care) whether or not taxi drivers get a better deal than Uber drivers. The reason I don't care is that taxi service is terrible, and I consider each taxi ride I've taken to be just shy of theft ... and this in NYC, Philly, Paris, Rome, Lyon, Atlanta, Le Mans, Berlin, Moscow, Abu Dhabi, Bejing and literally every place in the world where I've had the misfortune of hailing a cab.

2. You're categorically insane if you think taxi drivers will survive the arrival of driverless cars. Until that happens, the author's points may well hold.
It is widely believed that antioxidant supplements interfere with chemotherapy treatments, but it seems to be controversial subject. A relative of mine just started chemotherapy treatments and the doctors recommended avoiding antioxidants.
For years I've wondered why North America doesn't have more diesels like the majority of the rest of the world.

Then articles like this come along, and it's hard for me not to think there is a coordinated smear campaign against diesel.

I have to imagine big money is involved, though I don't know. Does anyone else feel the same way or have any input?
This is fantastic:

The major weakness of the ammonia blood test is that by the time the results are received by a treating physician, it is hour-old information that may not represent the true ammonia levels of a patient. The breath analyzer enables super-fast, repeatable testing so ammonia levels can be verified and treatment can begin immediately.

And:

Spearrin didn’t realize how hard this project was supposed to be until he called a respected expert on hyperammonemia for advice. Before Spearrin could ask his questions, the expert said, “You’ve chosen a horribly challenging project because ammonia is the most difficult molecule to measure and newborns are the most difficult patient population to work with.”

Spearrin replied, “But we’ve already built a working proto­type and we’ve tested it on two patients.”

And:

In just a year, the team had gone from a rough idea on paper to a working prototype, patient-tested. This is warp speed in the medical device world.
First of all, Google does take your content and make a product out of it by selling ad space on search result pages. Those pages would have no value for advertisers if it weren't for the content producers Google scraped to fill those pages up with.

Second, you linked to an api page that clearly says it was deprecated 5 years ago, come on. No one should ever feel bad about scraping Google, considering Google is the world's largest scraper themselves.
I like Tox, I've used it plenty to keep in touch with friends, the big issue that it faces is convincing people to use it rather than Skype. The privacy conscious seem to be more likely to switch over, though.
Another example of a touted inelegance which I consider to actually be incredibly helpful in practice is the positional arguments part of the post where the author says:

> For example, the Haskell function elem returns whether an element exists in a list. Do you call it with the list first or thing to search? There's no way to know.

Well, the type of `elem` is

(Eq a, Foldable t) => a -> t a -> Bool

So, it is - with practice - clear to see that the singular item comes first, and the item in the foldable container comes second. Perhaps this sort of Type-Driven Development, which is more of a practical mindset than language feature, isn't emphasized in the (excellent) books from which the author was learning...but it becomes an invaluable tool in Haskellers' toolboxes while trawling through package documentation later on. Many times, between the name of the function and type of arguments, one can figure out exactly what they need to pass in to achieve the desired output.
Any equity compensation depends on future liquidity which unicorns have much more of.
8 embargoed Xen Security Advisory to be released on 2015-10-29
> I often wonder if the whole idea of "typing" is the wrong decision in language design, if we shouldn't come up with something better.

Not sure what you mean by "better". A "type" is a proposition about the program. You can't get more general than that. Any static checking system will have an interpretation in terms of types, so it's hard to see what could possibly be better than a type system. There are just different type systems with different properties.
Ultimately neither are ideal for the environment, it's just diesel by products are worse for humans than gasoline and contribute more to smog.
Disagree entirely. 'Bigger' languages (think C++) are more difficult to learn. Haskell is a great functional language to start with - the language core is small, it's easy to use, and the 'purity' of the language means you don't start off cheating by using things like loops.
Here's Linode's notice: http://status.linode.com/incidents/ltchxw3jmx0s

They're rebooting Xen instances October 19 - October 27.
Depends on the major. I would say in many majors it's work experience that matters. I agree that the first job is easier to get when you're from Stanford, but that's it.
Google acquires 360-degree photography startup Digisfera to beef up Street View
The Euro 6 standard allows 0.08 g/km of NOx emissions for passenger diesel; the EPA allows a fleet average of 0.04.

The U.S. certainly is ahead of Europe on the regulation of toxic emissions, and European cities are much more likely than American ones to have dangerous levels of pollution:

http://www.nytimes.com/2014/12/31/upshot/pollution-around-th...
A more extreme form of whitespace sensitivity in C are the two following statements, which are identical and differ only in their whitespace.

x = y++ + z;
x = y + ++z;
Ok, but don't we have a body of knowledge on Alzheimer's that having another control group is redundant? Why do we keep needing new control groups for things that are going to kill people and we know are going to kill people? I cannot get by the ethical problem of knowing we're kill 50% of the people in the study to provide data we already have.
The Story of the Ermahgerd Girl
There's lots, if you search, e.g.:

https://news.usc.edu/63669/fasting-triggers-stem-cell-regene...

https://news.usc.edu/29428/fasting-weakens-cancer-in-mice/

https://news.usc.edu/78953/fasting-and-less-toxic-cancer-dru...
The History of American Surveillance
To me it feels like a microcosm of the difference between academic vs pragmatic thinking. The reason to use a quicksort is not because it's elegant and consise, it's because it is fast and memory efficient. When your implementation of an algorithm is actually an algorithm with asymptotically worse memory characteristics, it's not suitable for any real world production code, and this difference is _not_ pedantic.

This is what gets me: Haskell articles tend not to stop at presenting this is as a neat and elegant definition of a sort (which it is!) but emphasize that you're a just being picky if you're not willing to brush aside memory usage and reasoning about such in production code.
Just curious, are you a vi/emacs user by any chance?

Just because a UI is powerful does not mean it has to be unintuitive. Unity is a very powerful game engine and it has a very intuitive UI...

Let's not confuse the power of a software package with a powerful UI. Blender is the emacs/vi of 3D software - its UI is very unintuitive for beginners but extremely fast (and intuitive) to power users. Personally, I found that with Blender it's hard to master the basics but easy to learn the advanced stuff, once you have your basics down. With other packages I've used (3d max, Maya, Softimage) it may be easy to do a simple scene, but advanced stuff is very unintuitive to the point that you need a tutorial to do anything you haven't done before in that particular package.
It seems that this isn't an issue for Theranos's FDA-approved HSV-1 assay. See Table 16 and Figure 1: http://www.accessdata.fda.gov/cdrh_docs/reviews/K143236.pdf

However, the skill level of whoever performed the fingerpricks for that data may be significantly higher than the average technician at Theranos's wellness centers. And of course we have no idea about the hundreds of other tests. There seems to be some other correlation data on Theranos's site (https://www.theranos.com/our-lab - scroll down to 'Representative Clinical Correlations'), but there's no captions or text to provide context.
What I can conclude for sure is that the upvoting/downvoting system is very imprecise, but engaging at the same time.
Perhaps you should then say thats why you are in favor and not in plural. Especially since you are claiming that I am confusing your opinion with the authors.
Even the late stage investors probably made money. The only employees who didnt make money are the handful hired at the very end when the common valuation finally meets up with preferred.
I'm not sure the local whale population would be too happy with setting off something underwater to generate that much light. Would be interesting, though.
If you want a good education then an elite school isn't necessary.
If you want access to people and an unparalleled network, then your best option is an elite school.
Sorry, I'm having trouble finding that second link: shadio. Can you confirm that's their address? Interested in checking them out
Perhaps you should be less of a passive-agressive pedant. You're literally nitpicking over tense.

Consider it the royal "we", if it makes you feel better.
Every time I'm in Europe I'm amazed at how bad the air quality is. Do Europeans just not know that it doesn't have to be that way?

With compact cities and an acceptance of small cars, going electric seems natural for Europe.
So encourage your kids to be interesting people, don't create an artifical construction of interestingness.
I notice you are careful to say "potentially" because it never actually happens.
Nah, I think sustainability is a non-sequitur when talking about recorded material, whether physical, digital, or streaming revenue. Would I like for it to be different? Sure! But going back to the Bards who had to go from town to town, singing their songs for food and shelter, it's unreasonable to expect the synthetic protection of copyright to put more than peanuts on the table.

It's either make something, embrace the income potential, and keep creating, or whine with whisky an die in the gutter, figuratively speaking.
And what does your own condescending remarks add exactly? This was the page that was linked and frankly it wasn't good enough for HN nor did it reflect particularly good on front-end developers. Maybe something you yourself should think about when posting comments with a claimed employer in your profile.
Not a homework question. I am developing a new metric for reproducibility in scholarly publishing and trying to understand previous examples of successful models.
One thing you should know about Stuxnet that I can talk about publicly (I used to work for Siemens) is that it was an attack vector on part of the SCADA RTU drivers that ran on a very old and unpatched version of WindowsNT. People running an nuke plant on something that old (which is typical of Iran, considering how their politics have isolated them over the last 30 years) are kinda asking to get hacked like this.

Of course I'm not saying that this means the problem you're talking about isn't real: security is a real concern, especially with SCADA systems running energy plants. Just putting in some perspective.
Obama Admin Wants US Christians Monitored by New Homeland Security Program
1) I am not confusing anything. You said "we're" unless you talk about yourself in plural. I have had my fare share of cabs around the world too. To claim normal taxi in any normal city is terrible is absurd and just an attempt to pump up your position as being more rational than it is.

I don't care who gets a better deal either I just know that both solutions of upsides and downsides thats it. Coming out in defence for one or the other based on what O'reily does is where it goes wrong.

2) Why the strawman? Where did I ever claim such a thing?
As a society we have to either learn to handle not everyone needing to work, or we need to outlaw any progress which puts someone out of a job.

Personally I'd far rather see the dream of automation meaning people are no longer obliged to work. I believe we'd see massive improvements to quiality of life in so many ways, from the person who no longer has to break their back emptying bins to put food on the table, to the improved service in numerous industries where the people working are doing so out of choice. I also believe we could see massive leaps in art and science as people who previously spent their time working jobs they didn't want can dedicate it to something they're passionate about. How many great novels have been sacrificed in order to put food on the table?

No doubt some people in this world will choose to spend the time they would have been working drinking beer and watching TV. That's fine by me, supporting them is a price id I'd be willing to pay for people having the opportunity to do what they really love.
Perhaps you should not claim that I am confusing things when you are yourself unclear in your formulation.
The fact that high antioxidant levels could interrupt the ROS-p53 axis and prevent apoptosis (i.e. prevent cancer cells from dying) has been known for awhile.

https://en.wikipedia.org/wiki/Acetylcysteine#Adverse_effects

Edit: forgot to mention one of the relevant studies is from 2005.
The goal of startups is to enrich the founders, not be a net benefit for society.

If you have to destroy the world and crush employees to increase your net worth, that's just how the game is played.
But how can Americans socially signal their sophistication and enlightenment without talking about how much better things are in Europe?
If your truck gets better fuel economy than an equivalent unleaded engine, you are producing less CO2. The "40x" pollution number for the VW engines refers to nitrogen oxides only, which are bad for people but not the climate problem that CO2 is. Throwing that 40x number around while ignoring the CO2 and fuel economy seems very misleading.

Unless you've set up your truck to belch pillars of soot and smoke, I wouldn't worry about your purchase decision vs. gasoline.
Oh, he'll just call the cops to do his dirty work, don'cha know! The modern man doesn't believe in the 9+ minute response time of the 'average' police department, and would never deign to live in an area where the PD response is measured in hours (hello, Detroit!). The modern man will peaceably talk his intruder into a hearty early breakfast (or late night dinner) while waiting for the fuzz to arrive.

/s, in case anyone was curious.

The 'modern man' feels self reliance is antiquated and passé.
What The Voice can teach you about Venture Capital
Oh, well, pagerank is based off ranking published papers anyway: https://en.wikipedia.org/wiki/Citation_analysis
> while empires are created by war, they are very good at bringing peace and prosperity for long periods of time.

For the people /within that empire/. As the NSA and general US foreign policy have made abundantly clear, the US does not consider anyone outside of their national borders "part of the empire".

Your last paragraph sums it up nicely. Is "enjoying security treaties with the US" really a prerequisite for a prosperous life? Since no treaty with the US is purely military in nature, that sounds a lot like racketeering.
50+ mpg? What non-hybrid is that fuel efficient? I've seen almost none that beat even 40 combined city/highway
When did you use it last?

Did you watch any video tutorials?

What 3d apps do you like?

When I started about 15 years ago, Blender was much less intuitive and there was little tutorials and help. It helped that I used 3ds r4, 3ds Max, Auto Cad, and VIM... It still took many hours over a couple years to become comfortable with Blender.

They've since made everything MUCH more discoverable and organized. I've seen and helped young kids get started with it. I've also used/still have to use 3ds Max, Lightwave, Maya and others ...but Blender is my creative swiss army knife.

It's not perfect, but for ~95% of what I need it is... and it's still improving. Ton Roosendaal and others involved with this are awesome. I donated some to see it open sourced, and some since. My best investment ever.
Some comments here mention "AI driving the car" being the end game. I can't help but wonder what happens when a self driving car gets hacked, doors locked (unlocking disabled) and driven off a cliff.

Self driving cars will be magical and transformative but we don't really know what will happen. It may end up requiring a human co-driver to take over in case the algorithm misbehaves. So I do hope that self driving cars will come with regulation that mandates the presence of a licensed driver with ability to take over the manual controls.

Update:
Here is a small sample of articles about "non-hackable" systems getting hacked...

[1] Nuclear power plants: http://www.dailydot.com/politics/industrial-ethernet-switche....
[2] air-gapped computers: http://www.wired.com/2015/07/researchers-hack-air-gapped-com....
[3] autopilots: http://www.computerworld.com/article/2475081/cybercrime-hack....
reply
They're commonly used as such in several programming languages (https://en.wikipedia.org/wiki/Grave_accent#Use_in_programmin...), though, including Bash, D, Go, Ruby, MySQL, Markdown, etc.
Leaked Pinterest Documents Show Revenue, Growth Forecasts
> at least some of which--specifically information concerning intelligence operations the NSA conducted against Huawei--we know for a fact he shared with them.

Where is the evidence of this alleged fact?
Until driverless cars exist, it is better for the drivers correct?

And, driverless cars, if they do happen, will happen whether uber or lyft were around or not.

So in the mean time, having them around is better for drivers.
>You have not yet clarified regarding "sharing classified information with Chinese or Russians", either.

You keep drawing some distinction without a difference between "the leaks" and Snowden "directly handing over" the documents; either way, he is the author of their release and ultimately responsible for the consequences, and Americans are right to be angry with him for it.

> That said, though I am not of U.S. nationality neither by jus soli nor jus sanguinis, I do reside in the United States at present. Stay classy with your throwaway account.

You're a guest in this country; perhaps you could try acting like one?
I'm really glad to hear that, thank you.
the idea is here: https://thewinnower.com/papers/the-r-factor-a-measure-of-sci...
I agree.

What I am critiquing is the defence of Uber as if its somehow making it easier for drivers to make money. It's instituting competition between the drivers which is great for consumers.

But it's doing so to pay for getting rid of same drivers. Not just sometimes in the future, but actively right now.

No love for traditional taxis but as little love for companies who only take the best from hiring people as freelancers and the best from treating them as employees.
This is true. In fact I'd put the causality the other way -- Europeans are going slowly extinct precisely because of the unavailiability to the regular family of things they take for granted in America: big cars and big houses.

It's hard to have a second kid when you live in an apartment and drive a Fiesta, and it's really hard to justify a third. A fourth? Forget it.
Yep. The same as Texas.
Snowden didn't break the law. He uncovered other people breaking the law. If it is illegal to do something (like the NSA surveillance techniques) and that something is done then the rest of the laws surrounding state secrets automatically become devoid. That is the only way a sane working democratic society can function. If it is illegal to uncovered illegality then it sets a precedent that every witness to a crime will have to be tried as a defendant. The Snowden situation is absurd and anyone who says he broke the law is revealing themselves as the enemy of the people and of the country.
You've mixed and matched some of the stuff, leave wave-matter duality aside.
You can treat it as any other wave in that regards best analogy will be acoustic waves because they are very simple.
http://farside.ph.utexas.edu/teaching/em/lectures/node102.ht...
> He claims (with no way to verify) that he did not give them any classified information.

Innocent until proven guilty.

> If he had stayed in the United States, he would have had a trial.

Very debatable.
Yes, if I remember correctly his passport was revoked during the flight. There are not so many flights from Asia to South America, and many that do transit in Los Angeles, or other countries with extradition treaties.

Do you have any concrete info?
No it's not better for the drivers. It's better for the consumers.

The drivers are hired as freelancers but treated like employers.

How is that better for the drivers?