skysight-inc/HackerNews huggingface dataset:
So, by induction, I can take any currently approved molecule and apply a new formulation to it (time-release, liquid vs tablet vs aerosol, etc) and get exclusivity this way?

I thought the point was to take old drugs with no clinical data and get them back into the mainstream - this exclusivity was the carrot on the stick. But this seems more like a twist on that idea.
Using ES6 with Asset Pipeline on Ruby on Rails
>>Having said all that, why would one obsess about joining the elites. I am perfectly fine being (upper) middle class.

Indeed, and Notch pretty much confirms what I already believe it to be like way up at the top:

http://recode.net/2015/08/29/minecraft-billionaire-markus-pe...

I found it really insightful, especially the part where he tried to take care of people but they all ended up hating him regardless. Makes me wonder if a lot of rich people actually did care at one point but were typecast as villians no matter what they did and they eventually just give up.
Consumer is king.
Farms, maybe. Not without problems, though:

> In North Carolina, the heaviest logging is occurring in flood plains and wetlands that are among the region’s most productive natural habits. In Georgia, where most of the trees for wood pellets are grown on pine plantations, natural forests are rapidly disappearing as landowners see new opportunities to make money, said Ben Larson, forestry and bio-energy program manager for the National Wildlife Federation.

> The landscapes most at risk, Larson said, are traditional Southern savannas with a canopy of tall pines and an understory of grass and shrubs that provide food and shelter for wildlife. With more land converted to pines to make wood pellets, the vital understory is disappearing, replaced by stands of fast-growing pines that are raised as a cash drop.

https://www.washingtonpost.com/national/health-science/how-e...
>which makes it easy to design and evaluate language features in isolation.

Where can I see a demonstration of this? For example, what does it mean to evaluate something like decorators in Python and how will one go about doing that with lambda calculus?
Gives new meaning to Netflix & Chill.
From what I've heard Netflix has a great culture surrounding it.
It's refreshingly that we are losing our appeal for pure moneymaking. I'm not sure the attempted t was to portray him as a rogue so much as a jerk. And the article doesn't refute that.
If he really is that sharp, he deserves an Oscar for best actor, ever. Fooled so many people, for so long...

Listen, smart people don't go to Latin America and wonder if people there speak Latin. And smart people do NOT make so many terrible decisions.
Open source is generally quite kind to newbies, provided you provide that important context. Try to explain not just what you're doing, but also be very clear about why. Explain the problem as well as you can, and then discuss what solutions you've considered thus far.

It sounds like you have a good understanding of the problem. If anything, I'd look into why the route cache was removed; perhaps there was a good reason for this? If nothing else, you can ask and learn something.
“Am I Excited for a Market Crash?” an Article
I've never heard of this. What is the advantage over just using https via a VPN verified to do no logging?
Very interesting, and can be stated even more strongly. Even if the purpose of learning a language isn't business, the GDP per capita of the target language matters. Countries that are better off have more people with leisure time who you are likely to meet/interact with, and also tend to produce more interesting culture.
The point of ADT syntax is to allow deriving many functions on different data structures automatically. For example, lists and some functions can be defined as:

cons = (x list cons nil -> (cons x (list cons nil)))
nil = (cons nil -> (id nil))
map = (f list cons -> (list (comp cons f)))
head = (list -> (list (a b -> a) nil))
tail = (list cons nil -> (list (h t g -> (g h (t cons))) (const nil) (h t -> t)))
zip_with = (f a b -> ((left a) (right f b)))
left = (foldr (x xs cont -> (cont x xs)) (const []))
right = (f -> (foldr (y ys x cont -> (cons (f x y) (cont ys))) (const (const []))))
length = (flip comp const)

The very same definitions could be written more tersely as just:

List = #{Cons Type * | Nil}
cons = (Ctor 0 List)
nil = (Ctor 1 List)
head = (Getter 0 0 List)
tail = (Getter 0 1 List)
zip_with = (ZipWith List)
length = (Size List)

Where Ctor/Getter/ZipWith/Size are proper derivers. It is possible because all the information you need is there, but it is very hard to come up with those derivers and I currently only have some very bloated derivers for Scott encoded structures, and none for Church encoded structures yet.
I agree, I didn't realize Netflix did side projects like this, it definitely makes the company feel personable.
Google, please come to Myanmar.
Maybe Orwell's vision wasn't accurate. The title suggests Huxley got it right.
Maybe. Doesn't that strike you as the sort of thing the government would tell everyone, whether or not it's true?
Node in Production (slides)
> two of the three dudes in the video have beards

An irony that seems lost on too many here. I wondered if it was possibly a parody -- it has a Monty Python-esque quality to it; but, they are far too sincere for that. Perhaps they should say that once they reach their funding goal and/or feel confident enough with a prototype then they'll demonstrate by shaving with it. It begs questions, anyway.
Bankers, lawyers, and politicians have always been corrupt and/or incompetent. People still used to have kids.
This looks very interesting...
As far as I know, that's "regular gisp (rm $(command -v gisp); go get -u github.com/jcla1/gisp), and the full hello.go it produces is:

cat hello.gsp
(ns main
"/fmt"
"/net/http")

(def hello (fn [w r]
(fmt/fprintf w "hello")
()))

(def main (fn []
(http/handle-func "/" hello)
(http/listen-and-serve ":8080" nil)))

gisp hello.gsp

package main

import (
"/fmt"
"/net/http"
)

func hello(w, r core.Any) core.Any {
fmt.Fprintf(w, "hello")
return nil
}
func main() {
http.HandleFunc("/", hello)
http.ListenAndServe(":8080", nil)
}

(Which go won't compile due to errors with imports, missing core.Any
etc).

I realize hn isn't the best place to discuss issues, but if anyone have
played with gisp, and could shed some light (eg: maybe gisp is go 1.4
only?) that'd be great.

Incidentlially gsp/gspc seems to work as intended. Maybe I'm
misunderstanding the purpose of gisp?
Neat idea, disappointing execution. I actually just worked on a site with a similar concept. I think it delivers more palatable results, but I'd love to hear what others think: http://usofenergy.com
This is a good comment, but oddly leaves out the fact that, for many decades, it has been quite infamous that there is no universal agreement -- indeed it has been quite controversial -- as to whether the the different Chinese languages/dialects are in fact languages or dialects.

The by-now ancient joke is that a "language is a dialect with an army and navy".

Less jokingly, the different Chinese "dialects" share a written language, as above, but the other spoken "dialects" are largely unintelligible to those who have been exposed to only one of those spoken "dialects".
Specter: overcoming your fear of nested Clojure data
sigh That's what I get for making assumptions and not reading in depth enough. You're absolutely right, they're going to be leasing existing fiber.
If you like Star Wars, telnet towel.blinkenlights.nl
telnet towel.blinkenlights.nl
I have deep appreciation for pharmaceutical research, but it's folly to imagine any of it's ultimately driven by anything but profits.

I disagree with you. I remain convinced that research is driven by the curious geeks with a passion for solving the problem at hand.

Research is, unfortunately, funded by profiteering assholes.
Blood Moon and Lunar Eclipse
Could the U.S. Ever Adopt a Six-Hour Workday?
POWER OF GRAVITY – THE SOLAR TRACKER WITH WATER PURIFICATION
Is it really just a fun project? Or is Netflix trying to use this as the nose of the camel to get into the house automation business?

I've always thought house automation was cool, but a lot of trouble and likely to wind up a waste of my time and effort once I stop using it in three years because whatever standard I was using became obsolete. But if Netflix can start automating my house one bit at a time and slowly sneak up on me...
tl;dr = Google at first approved of the tactic these guys used then suddenly without warning changed their search algorithm and penalized these guys. Lesson, don't rely solely on Google to build traffic or you might lose a lot of money. They lost $400k in business from it.
As you can probably guess, I strongly disagree with this decision. TempleOS articles have been appearing regularly on HN because the dude behind it has realized it's a safe haven for his nonsense. There is nothing to be learned from it, it's the ravings of someone with mental illness. Indulging him and giving him this "safe haven" where he gets the impression that professional programmers are treating his garbage seriously is doing no one any favors. Nor is the minority of developers on HN who actually do take it seriously doing anyone any favors.

It certainly isn't helping the quality of content on HN, if that's all you care about.
Perhaps not specifically for support jobs, but for opportunities to join startups in whatever positions they can.
>> So while two people speaking different dialects may not be able to speak to each other because the tones and pronunciations of words are different, they most certainly can communicate by writing with each other because each dialect is just a different vocal representation of the same underlying language.

That's actually not true. Modern written Chinese is pretty much Mandarin Chinese. You can pronounce written Chinese with a non-Mandarin dialect but most of the times that is not how the dialect is spoken, and if you write the spoken form of a non-Mandarin dialect, there is a good chance that a lot of pieces of it won't make sense to someone who doesn't speak that dialect, on top of the fact that most dialects don't have a standardized written form in Chinese Characters. Most people speaking two different dialects can communicate via characters because they have learned written Mandarin.
It is interesting that after Numenta's flop we have Google Brain and the academic neural net community deploying amazing successes.
The fact that it's garbage which is totally unusable makes it not worth talking about. Someone investing a lot of effort in something doesn't make it good or worthy of discussion. There's lots and lots of stuff out there that mentally ill people have spent an incredible amount of effort on. This just happens to be one that keeps getting submitted to HN and that the HN admins have stupidly chosen to indulge.
No, he wasn't the brightest bulb in the box. Perhaps not the caricature the liberal media made him out to be, but still - we have enough of his gaffes on record (people in Latin America speaking Latin, etc.)
There are lots of problems here:

(1) Medicine has a very inelastic demand function. If you need substance X to stay alive, you'll pay anything to get it.

(2) Costs are hidden from consumers. If insurance / Medicare is paying for it, it literally makes no difference to the end user if it's $5, $50, or $50,000.

(3) Free-market forces are distorted by patent monopolies and lack of diversity in the supply chain. With a patent, you can crank up the price as high as you want. Ditto if you're the only supplier and it'll take some time for competitors to bring production online, or you can deny them access to samples for the equivalence testing your competitors need to prove to regulators that their drug is the same as your drug.

(4) Broken incentives for developing new drugs. A patient's going to be taking a drug to treat their diabetes / ED / high blood pressure for the rest of their life, whereas something like an antibiotic is only taken for a couple weeks. Guess which one is more profitable, hence attracts more R&D money?

What's the solution? I don't know. Maybe market reforms to align the incentives; perhaps even bounding pharmaceutical companies' profit margin to some multiple of their costs (but of course you'd have to be careful about the wording of the regulation and auditing for compliance, to make sure it can't be gamed by e.g. deliberately inflating the costs). Or perhaps even some kind of socialism where the government tells people what to produce or how much to sell it for (agricultural subsidies might be regarded similarly -- the government is deliberately manipulating the market to push down the price and push up the supply of goods necessary to sustain life, so shocks don't result in lethal shortages).

Bernie Sanders at one point talked about replacing patents for new drugs with prizes, but I think he may have given up on that.
"Red Yeast has not been banned, you just can't sell it as a treatment for high cholesterol."

Wikipedia disagrees with you. It says, if a product has a measurable amount of monacolin K, i.e., lovastatin in it the FDA will stop it's sale even if there aren't any claims of cholesterol reduction.

https://en.wikipedia.org/wiki/Red_yeast_rice#Regulatory_rest...
This is utter nonsense. Please explain the following:

1) Where are you getting the land use rights to set up "solar panels" on ~5-10% of all of the human-usable land on the planet? (if you had said solar thermal, that would have "only" (lol) been about half as much land)

2) What are these magic batteries that can store several days of base-load power? Given what goes into most battery technologies, this would probably be an even larger ecological disaster.

3) What do you think solar panels are made of? PV cells are very energy-expensive to manufacture, and they don't last forever.

4) Why are you pushing a technology that kills more people per kWh than nuclear?

You might want to research who is backing the push for solar/wind. Hint: their primary business would be hurt if nuclar started to become popular.
> but as far as I know it's pretty interesting technically

No, it isn't. It's garbage code written by someone who doesn't know what they are doing. It's no more interesting than a 1,000 page document written by a mentally ill person about lizard people.

> either discuss the actual stuff at hand, or if you think it doesn't belong here then flag it and move on

Unfortunately flagging it and moving on doesn't work because:

A) the dude uses sockpuppets.

B) The HN admins have chosen to indulge this crap.

It's been reappearing on here with some regularity and I'm tired of it. It's idiotic of this community to indulge this guy.
Show HN: Chrome extension to show comments with links
https://chrome.google.com/webstore/detail/hacker-news-show-links/phckhodapplnokiepnaneoglleghgpfi

Adds an item to the hackernews menu called "LinksOnly" which shows you how many links are found in the comment section for an entry and when clicked, toggles hiding comments that don't have links embedded in them.

Other things it does:
)changes default sorting for search to "ByDate"
) makes all links in comments and links to articles on the front page open in a new tab.
*) highlites links in yellow and visited links in pink

source: https://github.com/boomeasy/hnlinks
I'll just remind- remember everyone's skepticism of Wheeler. Judge each by their actions, there is time to tear them to shreds.
If they make it to a museum, then the information on the tablets becomes public and therefore very safe. Discovering and preserving the story is more important than the physical tablets.
This is fun, I like stuff like this; Not too serious and brings that sense of 'doing it yourself' feeling to it.
Douglas Crockford's JavaScript Encyclopedia
Townhall Q&A with PM Modi and Mark Zuckerberg at Facebook HQ
I don't remember the exact numbers, but they got something like 300K or, so, he got 2.5 billion. They didn't think it was fair as they put a lot of work into it ( perfectly legal, though, he owned it)
I honestly can't attribute any profiteering here. This is pure geek fun. Reminds me of the days of the Netflix Prize. http://www.netflixprize.com/
Everyone has gotten distracted by the infinite expansion and has missed the point of my question. Let me try again, with no infinite expansion.

The constructivist position is to refuse to accept the statement "every real number is either rational or irrational" because they're not in possession of proofs, for each possible real-valued expression, that its value is rational or, alternatively, a proof that its value is irrational. And yet, according to the quoted paragraph, they accept the statement "every integer is either even or odd", quote, "because we have an effective means of determining which alternative holds for any integer". My argument is that they should reject this statement on the same grounds: I named an integer whose value is not known, and therefore it is not known whether it is even or odd. There is not, in fact, an effective procedure for determining the evenness or oddness of the value of an arbitrary integer-valued expression. It's only after one actually knows the value that answering the question becomes easy.
Most likely the initial prototype was done during an hacktaton... I remember many years back someone that came up with a small TV on a toaster so we could say you can watch Netflix on your toaster, later on that toaster made it into a T-Shirt for the next hackaton!
Indeed, this is a cool project. Netflix seems to have a great work culture. The button design is neat, it can be used for different projects. A button can do many things :)
The hardest path to ultimate laziness, this looks like a fun project!
He was being sarcastic.
I recently discovered DTLS and QUIC, of which DTLS appear to be most interesting as a "general use" thing. We do of course not actually have a shortage of protocols, but it'd be nice to have something that was a little more suited for the "new" Internet. Full authentication/encryption, something lighter than TCP for multimedia -- and something that actually has a hope of crossing cheap DSL routers.

QUIC looks interesting, but a) is very concentrated on being a transport for http/2, b) is in flux, and c) Google apparently haven't donated any code that makes sense for production (excepting client-side in Chromium).

DTLS is closely connected with WebRTC, has several implementations (though, apparently no support in Erlang/Elixir yet?) and given the current push behind WebRTC appears to be here to stay.

Honestly, I don't know how interesting "hardware phones" are anymore. As long as one can get something to work over wlan with android, things "should" be real-world deployable. And I don't have 100s of SIP devices, so I don't need to care ;-).

It may turn out that wlan+android+WebRTC+DTLS never achieves the kind of latency needed for good live video/audio... I haven't experimented that much, but hopefully it's "good enough".

At any rate, appears that SIP really is the only interop that currently works. At first glance it does seem a little complex for the use-case of text messages, inconvenient in terms of addressing -- but maybe a core focused on WebRTC/IPv6 with gateways for SIP the way to go.

Either way, I guess as long as no big players want interop, it doesn't really matter. One'll just have to make a solution that works for inter-org/inter-friends communication, with the option to federate with those interesting in joining/building a new network. Doesn't look like it'll be easy to take a bite out of FB Messenger/Google Hangouts/WhatsApp etc.

https://webrtcglossary.com/dtls-srtp/
It was Dalrymple's site. His work was open source and collaborated with OpenWorm researchers. Looks like Dalrymple gave up to go work for Twitter. I guess he found a way to leverage his expertise in studying very small brains. Sigh. Greatest minds of our generation, yadda yadda.

https://en.m.wikipedia.org/wiki/David_Dalrymple_(computer_sc...
Yep. For the most part the elite will find a way to remain the elite, generation after generation after generation, unless there's a revolution. That won't change until human nature changes. Consequently, the rest of us with three choices.

(1) Start planning a real revolution, with all that entails. Good luck with that.

(2) Compete to be one of the very few who get invited to join the elite. Marrying in's the most reliable method, but that option's only available to half the population (approximately). Other than that, settle in for a brutal fight.

(3) Settle for being one of the nouveau riche. You might even be as rich as the elite in dollar terms, but you still won't really be part of the club and neither will your children. More likely you'll be in the economic tier just below the elite, which is a perfectly wonderful place to be.

Note that "change the game through legislation" and "whine about it" aren't on the list. Sorry. This is about the real world, and I'm trying to give practical advice.
Me and my siblings have a genetic mutation that requires us to take Colchicine 3 times/day for the rest of our lives so needless to say I am glad to see the drug industry being exposed.
Sequined Strapless Sweetheart Quince Gown
IANAM, but I think the difference comes down to the fact that we know the integer you are producing is one we possess a proof for. We do not know that for reals.
It's so far from a scalable product, I would guess it's not even a good test for market fit. Only a small subset of hackers/makers will tackle this. And, there's nothing to even buy from Netflix here...it's all stuff from other vendors.

I'm not saying it isn't on their radar, but this particular project is clearly for fun.
This is great and I love it but If the Raspberry Pi had a netflix client this would be amazing.
Predicting power consumptions with Hierarchical Temporal Memory
We're making good progress on multi-lingual support based on the Universal Dependencies scheme. We strongly value not rolling out features until they're ready for production use.

In most NLP libraries, you have to decode two things: what exists, and what you can actually build against. Often the first is well documented, but for the second you might be left with no comment at all, even if the model does not produce output usefully better than chance. You just have to try it out and see for yourself.

Multi-lingual support is not there yet. But when it is it'll be good.

Multi-lingual support is an important issue, and a key reasons I decided to relocate from Sydney and base the business in Berlin. My new co-founder, Henning Peters, is a native speaker of German.
Pixie – A Lightweight Lisp with 'Magical' Powers
Statins in general are relevant for a different reason - see "The Men Who Made Us Spend" episode 2, around 19:30 onwards (http://www.dailymotion.com/video/x23048w_the-men-who-made-us...).

Apparently some doctors consider statins to be overprescribed and Pfizer has worked hard to drive that - in 2012, Lipitor (Atorvastatin) became the best selling drug ever.
The market does not allow people like Roy Vagelos, Sigurd Varian or Bill Packard to thrive today, all we get instead is locusts like Valeant and Shkreli. That's the reality. The incentives are completely messed up, and there is no path to improvement.
FYI for the DIYers, there is a little project that I contribute to on the side for fun. I also use it to do things just like the title suggests:

https://home-assistant.io/
Decent read, but not a fan of the clickbait headline. Don't usually see this from TC.
The JavaScript Ecosystem Demystified
Girl suspended from school for wearing wrong shade of green
Is this best practices, manifesto, or both?
Yeah, it's cool, but it's not really a "major announcement."

Still, science marches forward.
This seems like something of a selection bias issue. By the same token, I don't know that I've run into anyone lately who's checked their phones while talking with me. Not to say that it doesn't happen, of course, but you might need to find new people.
And they expire after a year.