skysight-inc/HackerNews huggingface dataset:
From the article:

> A fosfoetanolamina, atualmente, possui dados experimentais concluídas de fase I, II e III.

The problem with the press coverage is that it has too few information. In this case it sounds too good to be true. Usually the drug is useful against some kind of cancers, but not against others. (For example, useful against fast growing cancers, but not useful against slow growing cancers.) I want a link to the a fase III study to see the relevant information.

Most press coverage have a few success stories, for example someone that had a 20% reduction of the cancer in the last months. (Usually it's a measurement problem, they take two images with slightly different methods, and the second image look smaller.) It's extremely suspicious that this article doesn't even have one of this anecdotes.
My Portuguese is terrible, but enough to parse that. The drug appears to be "fosfoetanolamina sintética" or synthetic Phosphorylethanolamine, which its Wikipedia page seems to say that it has anti cancer uses. As I have no bio chem or medical background I can't evaluate that claim.

The article says that it is formed by combining mono -ethanolamine with phosforic acid.
Harmitrage
Could you compare model-checkers like Spin and TLA+ with type-based approaches like F* and Coq, especially in terms of ease of use? The latter group doesn't seem to be getting much real-world usage, and I have the sense they are much harder to use.
This is awesome! building wine in pkgsrc is broken for me at the moment (clang problems), so having a working/up to date wine build on OS X is great!
Offline GnuPG Master Key and Subkeys on YubiKey NEO Smartcard
8 Agile startups – failure and success
If you like something like DOSbox but with better performance (near native, perhaps ?) you should have try DOSEmu.

Really, the difference of speed and performance is abysmal.

https://en.wikipedia.org/wiki/DOSEMU
Unity is coming to Apple TV
On the Android app there is. Choose the "View Contact" or "View Group" menu option from the top right and then change that contact or group's notification settings.
Attackers sever fiber-optic cables in San Francisco area, latest in a string
They could adopt a consistent EU response to economic migrants, and simply not let them leave.
Carlin talking about the Illuminati
Not only it is an inevitable fact of life, it (and death) is the single most important attribute of life. Especially in the case of humans aging and death limit the amount of damage one single person can do.

I'm not saying it's absolutely impossible to change. Just that it shouldn't.
Well, I suppose that vinyl could bring back the idea of paying for music.
Is there any interesting lecture that got you this far or did you study source code?
How is it protected from Sybil attacks on consensus algo? The algo description is definitely needed.
If you take a simple task and scale it by six or seven orders of magnitude, the result is anything but simple.
Some of the things listed in this article are more of a manager's role instead of a lead developer's role. With that being said, every company defines the lead developer role a bit differently.

For anyone that is interested in a lead developer role, you need to understand that there will be less coding. The amount of less coding is dependent on the company. Some companies expect 60% coding out of you and some companies expect a maximum of 10% coding out of you. If part of your tasks include delegating work to your coworkers… be prepared to give up the fun stuff. I often find myself doing the boring stuff so that the people that work for me can enjoy what they do. I personally enjoy the team lead role, but if you are interested in moving in to a team lead role, you should really understand what the company’s expectations are… because every company has different expectations for that role.
In some European countries (probably not Poland) the unemployment you get for about 2 years if you lose your job is sufficient to cover a mortgage. The philosophy is that it is cheaper for the state to help people stay in their existing home than to have them lose it and potentially have to house them and them never go back to being a net contributor.
This might be me being exceedingly charitable to the OP, but I see his point differently:

There's a ton of work involved in making a platform like WhatsApp a polished user experience. There's then a ton more work involved in making it _solid_. In choosing Erlang, they chose a platform that trivialises a large part (though not all) of the latter, allowing them to focus on the former.
For anyone else not up to spec on the lingo:

Definition of M0, M1, M2, M3, M4 [1]

>Different measures of money supply. Not all of them are widely used and the exact classifications depend on the country. M0 and M1, also called narrow money, normally include coins and notes in circulation and other money equivalents that are easily convertible into cash. M2 includes M1 plus short-term time deposits in banks and 24-hour money market funds. M3 includes M2 plus longer-term time deposits and money market funds with more than 24-hour maturity. The exact definitions of the three measures depend on the country. M4 includes M3 plus other deposits. The term broad money is used to describe M2, M3 or M4, depending on the local practice.

[1]: http://lexicon.ft.com/Term?term=m0,-m1,-m2,-m3,-m4
I know such environments exist, but programs in them aren't really "first-class citizens" of the platform; I'm not saying that people don't like it, but after all there's no mistaking that it's more like playing in a sandbox you can't get out of. "Why do I need this app just to run what I wrote? Why can't I make it do $something_native_apps_can?"

...although perhaps it would be a great time to talk about how things used to be different, when such questions come up.
If you are looking for crowd-sourced localized frequency information, check out http://www.radioreference.com
I really enjoyed The Eye of the World. I can't wait to start book 2. I have heard the series slows down considerably later on.But so far I love it.
I would assume they are in a very defensive mode and are thinking about liabilities and risks as they continue to hemorrhage employees and potential revenue. This makes it much more likely that they would try to protect themselves through any legal means possible. No company would plan on laying off 20k+ people without thinking about minimizing their liabilities and protecting their sources of business.
The UK and Ireland were given a waiver mainly because of their geographical situation (and there is a similar agreement beween them, the Common Travel Area)
Why do they have to call it a human tsunami? It's very disrespectful to the people fleeing from war zones.
> Qwerkywriter is a celebration of those who have chosen the path least traveled, the underdogs, the ones with the impractical college major.

This sentence makes me want to go crush the life of something beautiful. So goddamn pretentious and hipster.
Hey Luke, Just some points that may help your UX process. I don't want to share on twitter before I know what it is. What if I find out your product is terrible (obviously I'm hoping it's not or I wouldn't have bothered signing up for an invite)? If you're going to get people to request an invite put it as the text on the signup button rather than leading on with false advertising. Chances are I won't checkout your product now that you've made me wait. I'l get an email but it will be one of tens or even hundreds and I'll skip over it as I'm in my inbox to do something else and it will soon be forgotten. Rory
Student arrested after bringing homemade clock to school
Those that know don't have a tounge with which to tell the story.
Beyond the individual roles it would be nice to know about their organization.
> The single people strongly resented that because they felt they were being forced to work harder for the same pay since they made different life choices.

That's funny, because your life choices always determine how hard you have to work for the same pay in every other context, so why not this one? For instance, try making the same income after committing some crimes.
$300 isn't out of the ordinary, particularly when you throw in a custom metal base and effectively one-off production costs on top of your $200 starting figure.

The Ergodox will cost you nearly as much in materials, more pre-assembled.
Evernote, the first dead unicorn
It's sad when a kid builds something fun with Arduino and his own teachers are not smart enough to understand their smart student that is trying to learn on his own.
Machine Learning Books – reddit
I really enjoy playing vinyl from time to time; but I'm not going to pretend that they sound better. They don't. Vinyl is all about the touch and the feel, like driving a stick or making bread from scratch.
It's at the very least worrying that email is being controlled like this
Thanks!

I've been pondering about that too (mostly something with having a service worker drawing each char on a canvas, uploading that to a server), but keeping track of OS/Browser/vendor/font-setup/... (let alone getting it all out of the browser) makes it pretty hairy to get right.
> Many Europeans look enviously at Britain and Ireland, which were granted opt-outs when the treaty was signed, and still retain full border inspections — with some notable success in stopping terrorists and catching illegal immigrants.

I don't see the "notable success" as being substantiated.
What does this refer to?
The Cybersecurity Bill, Why All the Commotion?
What about this as a new side project idea:

A platform that allows you to find other random people at a similar stage in their side project and become 'buddies' and have to have a weekly catchup about your progress. Then you're both sort of accountable to your buddy, or at least have to report to them what you've done!
In my own experiments compressing pixel art, I found that gzipped .bmp files were smaller than the output of pngcrush just as often as they were larger. On average the pngs were slightly smaller, but you can tar together a whole bunch of similar bmps and gzip the lot, and then gzip really blows png out of the water. For a compressed file format specialised for images, I found png's performance very disappointing and decided not to use it.
If years after the Snowden revelation, no one has gotten a court to rule that blatant widespread constitutional violations took place at the NSA, you might want to reconsider your claim that there were blatant violations.
Lead here: My own experience with various companies has been that they expect 100% with the additional management work on top (like a cherry). You end up delegating a lot of things and get tired quickly. I'm currently working on re adjusting this issue and it's going much better. Still is a lot of work with little benefit. Except for the ability to help others grow into better devs. I love that part.
That'd be OpenSearch (http://www.opensearch.org/) in action.
>He's one of 4 remaining from the "blue days" (time with Digital); I think they'd be able to pull it off if they did go this route. They're all pretty awesome.

From personal experience, I want to add some long-term expectations about commanding premium consulting rates -- especially as it relates to vendor-proprietary knowledge.

I used to work for an enterprise software firm and was on their "crisis firefighting team". I'd travel to customer sites at less than 24 hours notice and fix their worst problems. These were the problems that were escalated to the CEO.

When I left the company and struck out on my own as a freelance "subject matter expert", I was able to command $300k a year for a few years. My background and rate was easy to sell: I was trained directly by the people who wrote the software.

The thing is that I always knew I was living on borrowed time because that high income was based on my previous association of being in the "inner circle" of how the software works. I had to diversify my skills away from that software because with each year that passed by, I became more of an "outsider" just like everyone else.

To relate to your dad's situation ... yes he's very good at what he does, but some of that value may also be his inside feed of information from HP. After he's separated from HP, as each new generation of server & printer hardware is released, his "aura" of HP knowledge can become outdated and less relevant value for customers. In other words, he needs to charge whatever premium rate he can, save as much as he can, all with an eye towards diversifying his income. Diversity could mean new tech skills such as learning AWS architecture or buying real estate to get income from rental properties.
The vinyl is a niche market. Very few people buy vinyls or even have a turntable at home. There used to be a market for djs but now it's gone, and the market for non professional is really tiny, it's not a viable option for independent artists , no matter what that article says. No they have a better shot at releasing their music for free on youtube, get some fame then get well paid gigs. Because the recording industry itself is dead.
Vinyl is a fun format. I've been picking up records for listening recently. One fun thing I noticed is most records have some hand-written notes along the inside edge of the record. Usually some album ID code, maybe a date, or some other markings I can't identify.

When I first noticed these, I thought, wow, it's crazy that someone had to mark up all these individual records as they were pressed. I can't believe how long that must have taken. Then I realized, obviously, that the master record had the original markings, and that entire record was stamped into the production run, including those hand-written markings. So some record engineer's handwriting survived onto thousands or millions of duplicated records, decades into the future, into my living room, where I noticed them. Neat! I wonder who that guy was...
Google Offices Around the World [Photos]
Beyond Good and Evil by Friedrich Nietzsche has been the most influential single text I’ve read in my life. Over the years, with each reread, it’s changed the way I look at the world. Before I read this book, I took the definitions for the words good and evil as givens and for granted.

It’s a book that I read, or read about, every time that I’m not convinced with my current beliefs. Out of every book Nietzsche wrote, this is the text that best sums up what I think he thought about in his spare time throughout his entire life in a physically detached but still coherent manner.
Buffon's needle
Support is planned!
I was interested in a startup in the cassette industry - No major research or anything, just a weekend idea I had once upon a time. Where does one find and market to the cassette fanbase?
This depends on one's jurisdiction, in the U.S. at least. For example, in Illinois, non-competes are generally enforceable.[0] In California, they are generally not.[1]

[0] http://www.isba.org/ibj/2012/01/lawpulse/employmentcovenants...

[1] http://www.cnet.com/news/calif-supreme-court-finds-noncompet...
Now that is awesome thank you! The more I have been looking into this the more I see how Racket could be the best tool for data munging.
A pretty nifty (if I do say so myself) project I implemented with OpenSeadragon.

http://beehivecollective.org/posterViewer/?poster=mr

I am NOT responsible for the art or narrative, just for putting it online with an OpenSeadragon-based implementation.

Source: https://github.com/jrochkind/beehive_poster_viewer

The Mesoamerica Resiste poster is an incredibly large high-res image, and OpenSeadragon works well for allowing very high-res zoom-in, with quick initial load. I had to fight with OSD a bit to get the UI I wanted, but once I spelunked through the source a bit I could usually figure out how to hook in to do what I needed. (And Javascript is not my most fluent language, which perhaps shows in my source). I'm pretty happy with OSD. Still a couple things that aren't quite right in my implementation, it gets confusing to figure out what's going on with high-res images and maintaining proper resolution (also not in my wheelhouse), and the version of OSD I was using didn't neccesarily always do the right thing with high-res "retina" displays (there were some improvements to this in master, not sure if they've been released yet). But overall, OSD is pretty amazingly high quality software, for free.

http://beehivecollective.org/posterViewer/?poster=mr#s=An%20...
> around 60% of your previous salary for a year

Two years actually, provided you have the right contract termination.
Maybe France really changed a lot. But be not mistaken: It is still the most bureaucratic country on earth. Anecdote: I'm doing a PhD in France. Each year, one has to do a re-inscription. In Germany, that means sending money to the university. In France, that means sending in – let me count, I have them on my desk – 17 documents, and to pay as well of course (preferred way: with a check. Like it is 50 years ago). The documents ask for tons of information they have already, like where I'm born. Included are things like "this document and do two copies" - it is still all analog. Absolutely disrespectful of my time.

And this is not a single occurrence, I got told that at school they are asking for documents for the kids as well each year, the same thing with information they already have.

On the other hand, doing the taxes was not at all complicated and I got proper help. This probably changed in the last years. It might be that this is a sign of a changing system, but there is still a lot of crust.
Plenty of prior art if you mean "round old-typewriter-style keycaps on a computer keyboard":

http://steampunkworkshop.com/keyboard-shtml/

A company also sells these (although they're much more expensive than the one in the article):

http://www.datamancer.net/keyboards/keyboards.htm
Our company is solving a similar large-scale problem with very few engineers. And our answer, too, is Erlang! (And also, a few very smart, highly experienced, people with Math graduate degrees.)
I agree. I'm just getting into it and building out a home stereo system, but I'm almost embarrassed to admit that I enjoy playing vinyl. It's because of junk like, "The reasons cited [for playing vinyl] are usually a fuller, warmer sound from vinyl’s analog grooves." No, no, no, don't associate me with that stupid audiophile nonsense.
See also http://media.ccc.de/browse/conferences/camp2015/camp2015-665...
Agreed. What might have been more informative would be to have instead sent them each other's profiles (or all the same profile) and see if they rated them as accurately when applied to themselves.
'Working together to beat the bad guys..' there really is no other way to deal with these growing threats
Google’s Demis Hassabis – misuse of artificial intelligence 'could do harm'
There is a huge difference between seeing an informed documentary and seeing an out of context video. For example, it's quite possible these people were rejecting food and water because they were tired of being beaten and hold up by the Hungarian police/military, as seen in lots of other videos. One should see these videos with an open mind and not with a preconceived idea because that's how it got us to be surprised by a young child drown in the beach when hundreds of others already had had the same fate or when we start saying they should stay on the neighbouring countries when, in fact, they already are, millions of them.

Obviously these people will behave like any other people would: in a possibly desperate and irrational way. Some would do some things they shouldn't and might end up in jail for it, some will not. It's up to each individual to fight in their own way.

Regarding your first point, you should really read about the United Nations World Food Programme which is the organism in charge of paying for all the food in these camps. From their own page[1]: "The World Food Programme (WFP) is struggling to meet the urgent food needs of close to six million displaced people in Syria and in neighbouring countries. Food operations are severely underfunded, meaning that WFP has been forced to reduce the level of assistance it provides to refugees across the region." More[2]: "1.7m Syrian refugees face food crisis as UN funds dry up". I have never been hungry in my life but it mustn't be what I would call being "good enough". I agree they are not dead though, just hungry.

[1] http://www.wfp.org/emergencies/syria
[2] http://www.theguardian.com/world/2014/dec/01/syrian-refugees...
Understanding Brute Force (2005) [pdf]
Vegans who run
Perhaps do it reddit-style - always show voting arrows, highlight current vote if there's one and allow re-voting? Cap the re-vote count if need be, but allow for at least one.
The Mathematical Hacker
Whose Side Is Twitter On?
Berlin meetup – tonight at Hops and Barley
I'm visiting Berlin as part of a year of travelling. I'm a serial web entrepreneur based in Silicon Valley.

If anyone would like to meetup over a beer tonight to talk startups, tech, VR, etc, let me know.
Very interesting, and quite impressive. I've used iipsrv in the past https://github.com/ruven/iipsrv http://iipimage.sourceforge.net/
I think the problem with medium is that it really markets to the self-congratulatory generation. I've read some really good articles on it, but so much of it is a product of a generation who expected the world and were upset when their expectations weren't met.
It's not exclusive. I know many startups who have one foot in the states, one foot in China (when some hardware is needed), and the head in France.
On a completely unrelated note, I just moved to São Carlos, and am looking to connect with the tech community here. Could you contact me via the email in my profile, and we could talk further?
Blazing fast app development with formular database
Ask HN: Mobile, social, geo all saturated – what's next?
Even American conspicuous consumerism seems to be on the wane. So what does an investor do?
Hi guys! I want to share with you what we've done during last several months.

Would love to hear your feedback!
Eh. I had a girlfriend like that. We're no longer friends because we'd end up with exchanges like this:

Me: Man, I miss camping. I once went to...

Her: I love camping! We should go sometime! There's this place...

Couple months later

Me: Hey, it's getting into fall and the weather's great. We've both got a couple long weekends coming up. Want to go camping on one of them?

Her: I hate camping.

Me: ...

(this is just a sample, the same thing happened on several, far more serious, issues that couples face)

Seriously, insincerity and dishonesty, even if you have yourself convinced of your lies in that moment, really fucking sucks.
another interesting read about the German vinyl industry:

http://www.welt.de/print/die_welt/hamburg/article126865000/D...

https://translate.google.com/translate?sl=auto&tl=en&js=y&pr...
How long have you been using whatsapp? Because only one spam message sounds like it's not a huge problem...
Obviously you're supposed to use an app for that. Using the browser on a mobile device? Don't be silly.
Systema Software leaks millions of health insurance records
It was a SpriteKit game, which has very similar APIs on both platforms, the differences are mostly on the inputs side...
We do have an initial hour meeting with candidates just to get to know them and propose the trial if they seem like a possibility.

Wouldn't most people take a day off to interview somewhere? I know I wouldn't be comfortable ducking out for a few hours to interview — it would feel tense and uncomfortable.

Facebook, and I'm sure many other places, do full-day interviews. It's certainly not unusual.