Search query: dr hoon hur

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abstract: Microorganisms facilitate the formation of a wide range of minerals that have unique physical and chemical properties as well as morphologies that are not produced by abiotic processes. Here, we report the production of an extensive extracellular network of filamentous, arsenic sulfide (As S) nanotubes (20 100 nm in diameter by 30 mm in length) by the dissimilatory metal reducing bacterium Shewanella sp. HN 41. The As S nanotubes, formed via the reduction of As(V) and S2O32 were initially amorphous As2S3 but evolved with increasing incubation time toward polycrystalline phases of the chalcogenide minerals realgar (AsS) and duranusite (As4S) Upon maturation, the As S nanotubes behaved as metals and semiconductors in terms of their electrical and photoconductive properties, respectively. The As S nanotubes produced by Shewanella may provide useful materials for novel nano and opto electronic devices.
author_names: Ji-Hoon Lee

Min-Gyu Kim

Bongyoung Yoo

Nosang Vincent Myung

Jongsun Maeng

Takhee Lee

Alice C Dohnalkova

James K Fredrickson

Michael Jay Sadowsky

Hor-Gil Hur
title: Biogenic formation of photoactive arsenic sulfide nanotubes by Shewanella sp. strain HN 41
venue: Proceedings of the National Academy of Sciences
year: 2007

abstract: We conducted an RNA sequencing study to identify novel gene fusions in 80 discovery dataset tumors collected from young patients with diffuse gastric cancer (DGC) Twenty five in frame fusions are associated with DGC, three of which (CLDN18 ARHGAP26, CTNND1 ARHGAP26, and ANXA2 MYO9A) are recurrent in 384 DGCs based on RT PCR. All three fusions contain a RhoGAP domain in their 3' partner genes. Patients with one of these three fusions have a significantly worse prognosis than those without. Ectopic expression of CLDN18 ARHGAP26 promotes the migration and invasion capacities of DGC cells. Parallel targeted RNA sequencing analysis additionally identifies TACC2 PPAPDC1A as a recurrent and poor prognostic in frame fusion. Overall, PPAPDC1A fusions and in frame fusions containing a RhoGAP domain clearly define the aggressive subset (7.5% of DGCs, and their prognostic impact is greater than, and independent of, chromosomal instability and CDH1 mutations. Our study may provide novel genomic insights guiding future strategies for managing DGCs.Diffuse Gastric Cancer (DGC) is increasingly being considered separate to intestinal type gastric cancer; several fusions events have been reported as drivers of the disease but few of those have been subsequently validated. Here the authors perform RNA seq on early onset DGC patients who had not been treated with chemotherapy or radiation and identify a previously unknown fusion.
author_names: Hanna Yang

Dongwan Hong

Soo Young Cho

Young Soo Park

Woo Ri Ko

Ju Hee Kim

Hoon Hur

Jongkeun Lee

Su-jin Kim

Sun Young Kwon

Jaehyuk Lee

Do Youn Park

Kyu Sang Song

Heekyung Chang

Min-Hee Ryu

Kye Soo Cho

Jeong Won Kang

Myeong-Cherl Kook

Nina Thiessen

Ann He

Andrew J Mungall

Sang-Uk Han

Hark Kyun Kim
title: RhoGAP domain containing fusions and PPAPDC1A fusions are recurrent and prognostic in diffuse gastric cancer
venue: Nature Communications
year: 2018

abstract: To evaluate whether the extracellular volume fraction (ECV) measured using cardiac magnetic resonance (CMR) imaging can detect myocardial tissue changes in dilated cardiomyopathy (DCM) without late gadolinium enhancement (LGE) Forty one DCM patients and 10 healthy volunteers underwent pre and post T1 mapping using a modified Look Locker Inversion recovery sequence, LGE, and cine MRI on a 3 T CMR system. LGE MR findings were used to divide DCM patients into two groups: Group A had no apparent LGE, and Group B had LGE apparent in at least one segment. The ECV of the left ventricle (LV) myocardium (16 segments) was calculated in the short axis view as follows: ECV (DR1 of myocardium/DR1 of LV blood pool) x (1 hematocrit) where R1 1/T1, DR1 post contrast R1 pre contrast R1. The LV ejection fraction (LVEF) was obtained from cine MRI images. The mean myocardial ECV in LGE segments in Group A B was compared to that of controls. The mean myocardial ECV in Group A was compared to that of LGE segments in Group B. The correlation between LV systolic function and the mean myocardial ECV of the whole myocardium was evaluated in all groups. Among the 41 DCM patients, 22 were in Group A, and 19 were in Group B. The mean ECV of DCM patents (n 41, 568 segments, 30.7 5.9) was significantly higher (P 0.001) than that of the control group (n 10, 157 segments, 25.6 3.2) The ECV was inversely related to LVEF in Group A (r 0.551, P 0.008) Group B (r 0.525, P 0.021) and Group A B (r 0.550, P 0.001) The ECV measured by MRI could be a useful parameter in evaluating diffuse myocardial changes in DCM patients.
author_names: Yoo Jin Hong

Chul Hwan Park

Young Jin Kim

Jin Hur

Hye Jeong Lee

Sae Rom Hong

Young Joo Suh

Andreas Greiser

Mun Young Paek

Byoung Wook Choi

Tae Hoon Kim
title: Extracellular volume fraction in dilated cardiomyopathy patients without obvious late gadolinium enhancement: comparison with healthy control subjects
venue: The International Journal of Cardiovascular Imaging
year: 2015

abstract: The complex structure and magnetism of Pr$_{2 x}$Bi$_x$Ru$_2$O$_7$ was investigated by neutron scattering and EXAFS. Pr has an approximate doublet ground state and the first excited state is a singlet. This overall crystal field level scheme is similar to metallic Pr$_2$Ir$_2$O$_7$ which is also reported here. While the B site (Ru) is well ordered throughout, this is not the case for the A site (Pr/Bi) A distribution of the Pr O2 bond length indicates the Pr environment is not uniform even for $x=0$ The Bi environment is highly disordered ostensibly due to the 6s lone pairs on Bi${3+ Correspondingly we find the non Kramers doublet ground state degeneracy otherwise anticipated for Pr in the pyrochlore structure is lifted so as to produce a quadrupolar singlet ground state with a spatially varying energy gap. For $x=0$ below T$_N$ the Ru sublattice orders antiferromagnetically, with propagation vector \textbf{k} (0,0,0) as for Y$_2$Ru$_2$O$_7$ No ordering associated with the Pr sublattice is observed down to 100 mK. The low energy magnetic response of Pr$_{2 x}$Bi$_x$Ru$_2$O$_7$ features a broad spectrum of magnetic excitations associated with inhomogeneous splitting of the Pr quasi doublet ground state. For $x=0$ $x=0.97$ the spectrum is temperature dependent (independent) It appears disorder associated with Bi alloying enhances the inhomogeneous Pr crystal field level splitting so that inter site interactions become irrelevant for $x=0.97$ The structural complexity for the A site may be reflected in the hysteretic uniform magnetization of B site ruthenium in the N\{e}el phase.
author_names: Joost van Duijn

K H P Kim

Nam Hwi Hur

D T Adroja

Frank G Bridges

Aziz Daoud-Aladine

Felix Fernandez-Alonso

Rocio Ruiz-Bustos

Jun Wen

V Kearney

Q Z Huang

Sang-Wook Cheong

Satoru Nakatsuji

Collin L Broholm

T G Perring
title: Induced quadrupolar singlet ground state of praseodymium in a modulated pyrochlore
year: 2017

abstract: Abstract We have studied the contact resistance (RC) between Au and a solution processed film of carbon nanotubes (CNTs) The test element group of the contact chain is modeled as a simple periodic series of resistors, the RC represents the resistor of the Au CNT contact. The contact resistivity (rC) was evaluated from RC by multiplying the contact area. When the sheet resistance (Rsh) of the CNT layer is 200 O/sq, the rC is 27 mO cm2, which is ~30 times of that of the Au IZO contact at the same Rsh. This is mainly due to the three dimensional shape of the CNT surface, resulting in a smaller contact area on the flat surface of the Au.
author_names: Seung Hoon Han

Sun Hee Lee

Ji Ho Hur

Jin Jang

Young-Bae Park

Glen C Irvin

Paul S Drzaic
title: Contact resistance between Au and solution processed CNT
year: 2010

abstract: Abstract Emission from two different peroxyoxalate chemiluminescence (PO CL) reaction pathways (i.e. 1,1' oxalyldiimidazole (ODI) and bis(2,4,6 trichlorophenyl)oxalate (TCPO) CL reactions) is significantly reduced in the presence of increasing Cu 2+ concentrations. The CL intensity decrease in the ODI CL reaction results from deactivation of the high energy intermediate(s) by Cu 2+ whereas the apparent quenching in the TCPO CL reaction results from both this effect and formation of Cu 2+ imidazole (ImH) complexes [Cu(ImH) n =1 4 2+ Because the reaction between Cu 2+ and ImH occurs competitively with the formation of a high energy intermediate (X) in TCPO CL reactions, accurately determining Cu 2+ concentrations with a TCPO CL based system is more difficult versus an ODI CL based system. Using ODI CL, the detection limit of Cu 2+ dissolved in water was determined to be 5.0 x 10 8 M (signal:noise 3) in a 1 cm fluorescence flow micro cell. ODI CL based systems are expected to be useful for the rapid quantification of many quenchers in environmental and biological samples because the interactions between the high energy intermediate(s) and quencher are very rapid relative to other competitive reactions.
author_names: Ji Hoon Lee

Jong Tae Je

Andrew Tartaglia

Jin Hur

Mark A Schlautman

Elizabeth R Carraway
title: Quantification of Cu2+ using 1,1' oxalyldiimidazole chemiluminescence
year: 2006

abstract: The effects of the active and passive protection mechanisms of powder beds on the sintering of Si 3 N 4 were investigated. Shrinkage, density, and coloring behavior of sintered samples were analyzed using different compositions and packing conditions of powder beds based on BN and Si 3 N 4 with different additives. Y 2 O 3 additive in the powder bed influences the weight change and phase formation behavior of the samples, although it has a very low vapor pressure at the sintering temperature. When MgO/Y 2 O 3 was used as sintering additives, the packing density and thickness of the powder bed had a much stronger effect than in the case of Al 2 O 3 /Y 2 O 3 For the optimization of the powder bed conditions, the vapor pressure and chemical stability of sintering additives at the sintering temperature has to be considered.
author_names: Sea Hoon Lee

Georg Rixecker

Fritz Dr Aldinger

Sung-Churl Choi

Keun Ho Auh
title: Effects of powder bed conditions on the liquid phase sintering of Si3N4
year: 2002

abstract: Today, network systems require higher bandwidth for applications such as fiber to the home communications. Gigabit passive optical network (GPON) links using a Fabry Perot laser are attractive solutions for this high speed network. However, due to the mode partition noise and fiber dispersion, GPON systems suffer from inter symbol interference (ISI) In this paper, we present an electronic dispersion compensator (EDC) that will improve a 1.25 Gb/s experimental GPON link. The experimental GPON link is simulated and measured with impairment assessment. An analog eye opening monitor, which captures the quality of the EDC output signal using the tunable delay and the integrator is proposed. The proposed EDC successfully compensates ISI for a given link with a 1.25 Gb/s signal. All circuits are fabricated using a 0.18mum CMOS process.
author_names: Kim Hyoungsoo

J de Ginestous

F Bien

Lee Kil-Hoon

Soumya Chandramouli

Hur Youngsik

C Scholz

Edward Gebara

Joy Laskar
title: An Electronic Dispersion Compensator (EDC) With an Analog Eye Opening Monitor (EOM) for 1.25 Gb/s Gigabit Passive Optical Network (GPON) Upstream Links
venue: IEEE Transactions on Microwave Theory and Techniques
year: 2007

abstract: Abstract Si 3 N 4 using Y 2 O 3 as a sintering additive provides good mechanical properties and high temperature oxidation resistance, but can suffer from crack formation when oxidized at 1000 degC. In order to minimize this problem, a SiO 2 layer was deposited onto Si 3 N 4 by the spray coating method. The dispersion of the SiO 2 slurry for the spray coating process was optimized, and dense silicate layers were formed by the spray coating and heat treatment in nitrogen atmosphere. Penetration of the coating layer into the sample was observed when the heat treatment temperature was higher than 1400 degC. The crystallization behavior of silicate coatings is similar to that of native oxide layers, but the formation of cristobalite is suppressed. The SiO 2 coating inhibits the rapid oxidation of Si 3 N 4 at 1000 degC effectively.
author_names: Sea Hoon Lee

Georg Rixecker

Fritz Dr Aldinger

Sung-Churl Choi

Keun Ho Auh
title: Effect of spray coated SiO2 layers on the low temperature oxidation of Si3N4
year: 2003

abstract: Becker's nevus, a cutaneous hamartoma, usually occurs as a large, unilateral, hyperpigmented and hypertrichotic patch on the shoulder or upper trunk, which can be present in childhood or adolescence. Becker's nevus can be treated with traditional laser therapy using various types of lasers including a 532nm potassium titanyl phosphate (KTP) laser, 694nm ruby laser and 755nm alexandrite laser. However, this may cause harmful side effects such as scarring, mottled hypopigmentation, post inflammatory hyperpigmentation (PIH) purpurae, and crusts. As a result, no standard for the treatment of Becker's nevus using lasers has been established. Therefore, this study was implemented to investigate the safety and efficacy of treating Becker's nevus using Dr. Hoon Hur's Golden Parameter Therapy (GPT) followed by Dr. Hoon Hur's Optimal Melanocytic Suicide 1 Parameter Therapy (OMS 1 PT) which uses a high fluence 1064nm Q switched Nd: YAG laser (QSNL) Forty two Koreans suffering from Becker's nevus participated in the study and received treatment on a weekly basis for 75 100 sessions using the QSNL according to Dr. Hoon Hur's GPT then followed by Dr. Hoon Hur's OMS 1 PT. The parameters for this study were a spot size of 7 mm, a fluence of 2.2 J/cm2 and a pulse rate of 10 Hz using a sliding stacking technique for a single pass over the Becker's nevus, followed by Dr. Hoon Hur's OMS 1 PT using a sliding technique for 5 passes with the QSNL over the Becker's nevus. Upon completion of the last treatment, all 42 patients with Becker's nevus were cured, having no side effects, and entirely removing the pigmented lesions. None of the 42 patients reported any recurrences after their follow ups 6 15 months after the final treatment. As a result of this study, we propose therapy to safely and effectively treat Becker's nevus using a fusion of Dr. Hoon Hur's GPT and Dr. Hoon Hur's OMS 1 PT with a high fluence 1064nm QSNL to avoid any recurrences or harmful side effects.
author_names: Hoon Hur

Ji Hoon Kim

Duck Taik Shim

Suk Jin Choi

Pyoung Su Kim

Yu Ri Kim
title: The Treatment of Becker's Nevus by Combination Therapy: Dr. Hoon Hur's Golden Parameter Therapy and Dr. HOON Hur's Optimal Melanocytic Suicide 1 Parameter Therapy
year: 2021