Search query: transferred via contacts

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abstract: Two dimensional semiconductors have a number of valuable properties that could be used to create novel electronic devices. However, creating 2D devices with good contacts and stable performance has proved challenging. Here we show that transferred via contacts, made from metal embedded in insulating hexagonal boron nitride and dry transferred onto 2D semiconductors, can be used to create high quality 2D transistors. The approach prevents damage induced by direct metallization and allows full glovebox processing, providing a clean, stable and damage free platform for 2D device fabrication. Using the approach, we create field effect transistors (FETs) from bilayer p type tungsten diselenide (WSe2) that exhibit high hole mobility and low contact resistance. The fabricated devices also exhibit high current and stability for over two months of measurements. Furthermore, the low contact resistance and clean channel allow us to create a nearly ideal top gated p FET with a subthreshold swing of 64 mV per decade at 290 K.Bilayer WSe2 field effect transistors with near ideal device characteristics can be created using transferred via contacts made from metal embedded hexagonal boron nitride.
author_names: Younghun Jung

Min Sup Choi

Ankur Nipane

Abhinandan Borah

Bumho Kim

Amirali Zangiabadi

Takashi Taniguchi

Kenji Watanabe

Won Jong Yoo

James C Hone

James T Teherani
title: Transferred via contacts as a platform for ideal two dimensional transistors
venue: Nature Electronics
year: 2019

abstract: The purpose of this study was to determine whether information of the homeopathic remedy "Cerebrum Compositum" transferred via a "biophoton therapy device" exerts an effect on isolated rat cortical neurons when tested versus untreated control. 60 x 103 neurons were used per group according to treatment in each of 4 experiments. Viability after 10 days was defined by a) synaptic size, b) the number of synaptic contacts and c) by longevity. Synaptic size in the test group was 63% greater (i.e. equal to 163% of) as compared to control W0 (100% (p<0.01) The number of synaptic contacts in the test group was 49% greater (i.e. equal to 149% of) than W0 (p<0.01) These trends could also be observed in the 4 sub experiments separately. There was no difference between the groups respecting longevity. Data are in line with previous findings on information transfer via the biophoton therapy device.
author_names: Dietrich Vastenburg

Sjoerd Pet
title: A follow up study on the morphology of isolated rat cortical neurons and information transferred via a "biophoton device"
year: 2012

abstract: Helices represent the most abundant secondary structure motif in proteins and are often involved in various functional roles. They are stabilized by a network of hydrogen bonds between main chain carbonyl and amide groups. Several surveys scrutinized these hydrogen bonds, mostly based on the geometry of the interaction. Alternatively, the topological analysis of the electron density provides a powerful technique to investigate hydrogen bonds. For the first time, transferred experimental charge density parameters (ELMAM database) were used to carry out a topological analysis of the electron density in protein helices. New parameters for the description of the hydrogen bond geometry are proposed. Bonding contacts between the amide N and carbonyl O atoms (N**O) of helices, poorly addressed in the literature so far, were characterized from topological, geometrical, and local energetic analyses. Particularly, a geometrical criterion allowing for the discrimination between hydrogen bonds and N**O contacts is proposed.
author_names: Dorothee Liebschner

Christian Jelsch

Enrique Espinosa

Claude Lecomte

Eric Chabriere

Benoit Guillot
title: Topological analysis of hydrogen bonds and weak interactions in protein helices via transferred experimental charge density parameters.
venue: The journal of physical chemistry. A
year: 2011

abstract: Thermodynamic limit of magnetization corresponding to the intact proton bath usually cannot be transferred in a single cross polarization contact. This is mainly due to the finite ratio between the number densities of the high and low gamma nuclei, quantum mechanical bounds on spin dynamics, and Hartmann Hahn mismatches due to rf field inhomogeneity. Moreover, for fully hydrated membrane proteins refolded in magnetically oriented bicelles, short spin lock relaxation times (T1r) and rf heating can further decrease cross polarization efficiency. Here we show that multiple equilibrations re equilibrations of the high and low spin reservoirs during the preparation period yield an over twofold gain in the magnetization transfer as compared to a single contact cross polarization (CP) and up to 45% enhancement as compared to the mismatch optimized CP MOIST scheme for bicelle reconstituted membrane proteins. This enhancement is achieved by employing the differences between the spin lattice relaxation times for the high and low gamma spins. The new technique is applicable to systems with short T1r's, and speeds up acquisition of the multidimensional solid state NMR spectra of oriented membrane proteins for their subsequent structural and dynamic studies.
author_names: Wenxing Tang

Alexander A Nevzorov
title: Repetitive cross polarization contacts via equilibration re equilibration of the proton bath: Sensitivity enhancement for NMR of membrane proteins reconstituted in magnetically aligned bicelles.
venue: Journal of magnetic resonance
year: 2011

abstract: Slow domains in oxygen doped n type GaAs with photoexcited conductivities ranging from 10 8 to 10 4 Omega CM) 1 have been investigated in the temperature range 100 to 200 K. It is proposed that the origin of these domains is the transferred electron effect with enhanced trapping from the (100) valley. The low threshold voltages are attributed to high resistance layers near the alloyed contacts of width about 10 mu m in low resistivity samples and about 100 mu m in high resistivity samples. A theoretical model is proposed for the domain incubation which invokes a sub nl product behaviour of the cathode layer and compared with experimental results of incubation time against applied field and the variation of threshold field with sample length. The trap modified drift velocity against field curve has been calculated from the results of Fawcett et al (1970) for the transferred electron effect in pure GaAs at 300K. The ratio of the capture time in the (000) valley to that in the '100) valley is estimated to be about thirty from the measured extra domain drift velocity, which was 4*105cm s 1 at temperatures around 150 K.
author_names: B K Ridley

Jacob Crisp

F Shishiyanu
title: Slow domains and negative resistance via the enhanced capture of transferred electrons in n type GaAs
year: 1972

abstract: The present study is dedicated to an experimental microkinetic approach of the catalyst oxidation of the diesel soot using a filter coated with ceria. To mimic the situation encountered in this process, mechanical ceria/soot mixtures have been prepared according to the tight and loose contact concepts described in the literature with ceria/soot ratio R 1. Diesel soots prepared on an engine test bench and commercial soot have been used. The evolution of the ceria/soot contacts (via the amount of oxygen transferred from ceria to soot) with the progressive oxidation of the soot is followed using temperature programmed experiments (denoted as TPEs) that provide the rate of CO2 and CO productions [denoted as RCO2(T) and RCO(T) during the increase in the temperature in helium in the range of 300 1100 K. During the first TPE, different surface processes implying pure soot and ceria contribute to RCO2(T) and RCO(T) making the evaluation of the oxygen transfer difficult. It is shown that these difficulties are.
author_names: Badr Bassou

Nolven Guilhaume

Karine Lombaert

Claude Mirodatos

Daniel Bianchi
title: Experimental Microkinetic Approach of the Catalytic Oxidation of Diesel Soot by Ceria Using Temperature Programmed Experiments. Part 1: Impact and Evolution of the Ceria/Soot Contacts during Soot Oxidation
year: 2010

abstract: Type I interferon (IFN I) is critical for antiviral defense, and plasmacytoid dendritic cells (pDCs) are a predominant source of IFN I during virus infection. pDC mediated antiviral responses are stimulated upon physical contact with infected cells, during which immunostimulatory viral RNA is transferred to pDCs, leading to IFN production via the nucleic acid sensor TLR7. Using dengue, hepatitis C, and Zika viruses, we demonstrate that the contact site of pDCs with infected cells is a specialized platform we term the interferogenic synapse, which enables viral RNA transfer and antiviral responses. This synapse is formed via aLb2 integrin ICAM 1 adhesion complexes and the recruitment of the actin network and endocytic machinery. TLR7 signaling in pDCs promotes interferogenic synapse establishment and provides feed forward regulation, sustaining pDC contacts with infected cells. This interferogenic synapse may allow pDCs to scan infected cells and locally secrete IFN I, thereby confining a potentially deleterious response.
author_names: Sonia Assil

Severin Coleon

Congcong Dong

Elodie Decembre

Lee Sherry

Omran Allatif

Brian Webster

Marlene Dreux
title: Plasmacytoid Dendritic Cells and Infected Cells Form an Interferogenic Synapse Required for Antiviral Responses.
venue: Cell host microbe
year: 2019

abstract: Abstract Background Respiratory viruses on fomites can be transferred to sites susceptible to infection via contact by hands or other fomites. Methods Care for hospitalized patients with viral respiratory infections was observed in the patient room for 3 hour periods at an acute care academic medical center for over a 2 year period. One trained observer recorded the healthcare activities performed, contacts with fomites, and self contacts made by healthcare workers (HCWs) while another observer recorded fomite contacts of patients during the encounter using predefined checklists. Results The surface contacted by HCWs during the majority of visits was the patient (90% Environmental surfaces contacted by HCWs frequently during healthcare activities included the tray table (48% bed surface (41% bed rail (41% computer station (37% and intravenous pole (32% HCWs touched their own torso and mask in 32% and 29% of the visits, respectively. HCWs' self contacts differed significantly among HCW job roles, with providers and respiratory therapists contacting themselves significantly more times than nurses and nurse technicians (P .05) When HCWs performed only 1 care activity, there were significant differences in the number of patient contacts and self contacts that HCWs made during performance of multiple care activities (P .05) Conclusions HCWs regularly contact environmental surfaces, patients, and themselves while providing care to patients with infectious diseases, varying among care activities and HCW job roles. These contacts may facilitate the transmission of infection to HCWs and susceptible patients.
author_names: Linh T Phan

Dayana Maita

Donna C Mortiz

Susan C Bleasdale

Rachael M Jones
title: Environmental Contact and Self contact Patterns of Healthcare Workers: Implications for Infection Prevention and Control
venue: Clinical infectious diseases an official publication of the Infectious Diseases Society of America
year: 2019

abstract: During the evaluation of forensic DNA evidence in court proceedings, the emphasis previously placed on the source of the DNA is progressively shifting to the consideration of the activities resulting in its deposition. While direct contact and deposition may be a likely explanation, alternative scenarios involving DNA transfer through a secondary person or medium are important to consider. Here we assessed whether non self DNA, indirectly transferred via a handshake, could be detected on surfaces contacted by the opposing hand shaker after 15min, and considered the variables affecting its persistence in subsequent contacts. In general, the depositor of the handprint was the major contributor to DNA profiles collected from handprints placed on glass plates. Minor contributions from the opposing hand shaker (as a known contributor) were detected at a lower rate, decreasing as the number of contacted items increased post handshake. Delays in deposition also affected the detection of the opposing hand shaker, with a 15min delay between handshaking and contact resulting in the reduced presence, and corresponding LRs, of the known contributor. The handprint depositor was excluded from their own handprint on several occasions, including instances where the opposing hand shaker was not excluded from the same profile. Several factors appeared to strongly influence the detection of both the depositor and contributing individual involved in the handshake. The relative shedding ability of the pair had the largest effect, where good shedders (whether depositor or contributor) could swamp poor to moderate shedders, while the pairing of two moderate or two poor shedders could result in the detection of both individuals. When the deposition of a handprint was delayed, the activities performed by the individual had a substantial effect on the resultant detection of the contributing profile multiple contacts with the same items increased the likelihood that the known contributor's DNA would be retained and subsequently detected, through the parking and re transfer of DNA on used items.
author_names: Bianca Szkuta

Kaye N Ballantyne

Roland A H van Oorschot
title: Transfer and persistence of DNA on the hands and the influence of activities performed.
venue: Forensic science international. Genetics
year: 2017

abstract: The past decade has seen striking progress in our understanding of communication between organelles via close appositions of their membranes, known as contact sites. Recent systematic studies highlight that the cellular contact site landscape is much more intricate than previously anticipated and that most, if not all, organelles are capable of establishing such contacts with one another. Hence, the big challenge for this research field is to now step outside the comfort zone of the few highly studied examples of contact sites and a handful of molecules that are transferred at these sites, and to investigate the diversity of organelle contacts and the plethora of their cellular roles.Cellular organelles extensively communicate with each other by close interactions, known as membrane contact sites. Schuldiner and Bohnert comment on the progress of this rapidly developing field, highlighting that the complexity of interactions at membrane contact sites is only now starting to emerge.
author_names: Maria Bohnert

Maya Schuldiner
title: Stepping outside the comfort zone of membrane contact site research
venue: Nature Reviews Molecular Cell Biology
year: 2018