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abstract: It is widely thought that the water oxidation reaction limits the maximum work function to about 5.25 eV for hole doped semiconductors exposed to the ambient, constrained by the oxidation potential of air saturated water. Here, we show that polymer organic semiconductors, when hole doped, can show work functions up to 5.9 eV, and yet remain stable in the ambient. We further show that de doping of the polymer is not determined by the oxidation of bulk water, as previously thought, due to its general absence, but by the counter balancing anion and its ubiquitously hydrated complexes. The effective donor levels of these species, representing the edge of the 'chemical' density of states, can be depressed to about 6.0 eV below vacuum level. This can be achieved by raising the oxidation potential for hydronium generation, using large super acid anions that are themselves also stable against oxidation. In this way, we demonstrate that poly(fluorene alt triarylamine) derivatives with tethered perfluoroalkyl sulfonylimidosulfonyl anions can provide ambient solution processability directly in the ultrahigh workfunction hole doped state to give films with good thermal stability. These results lay the path for design of soft materials for battery, bio electronic and thermoelectric applications.
author_names: Qi-Mian Koh

Cindy Guanyu Tang

Mervin Chun-Yi Ang

Kim-Kian Choo

Qiu-Jing Seah

Rui-Qi Png

Lay-Lay Chua

Peter K H Ho
title: Overcoming the water oxidative limit for ultra high workfunction hole doped polymers
venue: Nature communications
year: 2021

abstract: Perovskite light emitting diodes (PeLEDs) based on three dimensional (3D) polycrystalline perovskites suffer from ion migration, which causes overshoot of luminance over time during operation and reduces its operational lifetime. Here, we demonstrate 3D/2D hybrid PeLEDs with extremely reduced luminance overshoot and 21 times longer operational lifetime than 3D PeLEDs. The luminance overshoot ratio of 3D/2D hybrid PeLED is only 7.4% which is greatly lower than that of 3D PeLED (150.4% The 3D/2D hybrid perovskite is obtained by adding a small amount of neutral benzylamine to methylammonium lead bromide, which induces a proton transfer from methylammonium to benzylamine and enables crystallization of 2D perovskite without destroying the 3D phase. Benzylammonium in the perovskite lattice suppresses formation of deep trap states and ion migration, thereby enhances both operating stability and luminous efficiency based on its retardation effect in reorientation. Ion migration can induce overshoot of luminance in normal 3D perovskite light emitting diode devices and results in reduced lifetime. Here Kim et al. show that the ion migration and overshoot can be suppressed in 3D/2D hybrid perovskites, leading to 21 times longer operational lifetime.
author_names: Hobeom Kim

Joo Sung Kim

Jungwoo Heo

Mingyuan Pei

In-Hyeok Park

Zhun Liu

Hyung Joong Yun

Min-Ho park

Su-Hun Jeong

Young-Hoon Kim

Jin-Woo Park

Emad Oveisi

Satyawan Nagane

Aditya Sadhanala

Lijun Zhang

Jin Jung Kweon

Sung Keun Lee

Hoichang Yang

Hyun Myung Jang

Richard H Friend

Kian Ping Loh

Mohammad Khaja Nazeeruddin

Nam-Gyu Park

Tae-Woo Lee
title: Proton transfer induced 3D/2D hybrid perovskites suppress ion migration and reduce luminance overshoot
venue: Nature Communications
year: 2020

abstract: Atopic dermatitis (AD) is a multifactorial, heterogeneous disease associated with epidermal barrier disruption and intense systemic inflammation. Previously, we showed that exosomes derived from human adipose tissue derived mesenchymal stem cells (ASC exosomes) attenuate AD like symptoms by reducing multiple inflammatory cytokine levels. Here, we investigated ASC exosomes' effects on skin barrier restoration by analyzing protein and lipid contents. We found that subcutaneous injection of ASC exosomes in an oxazolone induced dermatitis model remarkably reduced trans epidermal water loss, while enhancing stratum corneum (SC) hydration and markedly decreasing the levels of inflammatory cytokines such as IL 4, IL 5, IL 13, TNF a, IFN g, IL 17, and TSLP, all in a dose dependent manner. Interestingly, ASC exosomes induced the production of ceramides and dihydroceramides. Electron microscopic analysis revealed enhanced epidermal lamellar bodies and formation of lamellar layer at the interface of the SC and stratum granulosum with ASC exosomes treatment. Deep RNA sequencing analysis of skin lesions demonstrated that ASC exosomes restores the expression of genes involved in skin barrier, lipid metabolism, cell cycle, and inflammatory response in the diseased area. Collectively, our results suggest that ASC exosomes effectively restore epidermal barrier functions in AD by facilitating the de novo synthesis of ceramides, resulting in a promising cell free therapeutic option for treating AD.
author_names: Dae Hyun Ha

Debra Crumrine

Joan S Wakefield

Bogyeong Kim

Sungeun Kim

Hyun-keun Kim

Joon Lee

Jun Ho Lee

Peter M Elias
title: Exosomes from Human Adipose Tissue Derived Mesenchymal Stem Cells Promote Epidermal Barrier Repair by Inducing de Novo Synthesis of Ceramides in Atopic Dermatitis
venue: Cells
year: 2020

abstract: Despite increasing efforts to decarbonize the power sector, the utilization of natural gas fired power plants is anticipated to continue. This study models existing solventbased carbon capture technologies on natural gas fired power plants, using site specific emissions and regionally defined cost parameters to calculate the cost of CO2 avoided for two scenarios: delivery to and injection within reliable sequestration sites, and delivery and injection for the purpose of CO2 enhanced oil recovery (EOR) Despite the application of credits from the existing federal tax code 45Q, a minimum incentive gap of roughly $38/ tCO2 remains for the geologic sequestration of CO2 and $56/tCO2 for CO2 EOR (before consideration of revenue generated from delivered CO2 contracts) At full escalation of 45Q, delivered CO2 costs from this sector for geologic sequestration could reach as low as $22/tCO2. However, given the capital investment required in the near term, it would be beneficial if the credit provided the greatest economic benefit early on and decreasing over time as deployment continues to ramp up. Additionally, due to the high qualifying limit of 45Q for the power sector, e.g. 500 ktCO2/yr, the tax credit incentivizes the capture of roughly 397 MtCO2/yr at a 90% capture efficiency or 75% of the emissions in this sector, with missed opportunities equating to roughly 118 MtCO2. Advancing the scale of carbon capture and sequestration (CCS) will require both technological advances in the capture technology, cost reductions through the leveraging of existing infrastructure, and increased policy incentives in terms of cost along with the reduction of qualifying limits. INTRODUCTION Roughly 1500 million tonnes of CO2 were generated from the combustion of natural gas in the United States in 2018, representing 33% of fossil based emissions. The technology exists today to avoid roughly half of these emissions through the direct installation of carbon capture and sequestration (CCS) at large (i.e. >100 000 tonnes CO2/yr or 100 ktCO2/ yr) point sources consisting mostly of the industrial and electric power sectors (Figure 1) As demonstrated in Figure 2, of all natural gas fired power plants in the United States, roughly 37% qualify for the federal tax credit 45Q, provided they capture greater than 500 ktCO2/yr. This represents 397 MtCO2/yr or 26% of total emissions associated with natural gas and 75% of emissions of natural gas used for the power sector. Facilities that capture carbon and sequester it geologically or use it for CO2 enhanced oil recovery (EOR) are eligible for 45Q. In the case of CO2 used for EOR, the federal tax credit was $15.29/tCO2 in 2018 and grows linearly in value to $35/tCO2 by 2026. For geologic sequestration of CO2, the credit was $25.70 per ton in 2018 and similarly will grow to $50/tCO2 by 2026. In fact, in many cases, emissions are much higher than 500 ktCO2/yr. For example, in the Southeastern region of the United States, there are 28 natural gas plants that produce over 2 MtCO2 annually, with the largest plant producing more than 7 MtCO2/yr alone. Although the U.S. dependence on coal is still strong, representing 65% of U.S. electricity related emissions in 2018, it has exhibited a decline in primary energy consumption of 8.0% from 2017 to 2018 and roughly 27% over the past 5 years. Meanwhile, following an increase in production, the primary consumption of natural gas grew 6% from 2017 to 2018 and roughly 12% over the past 5 years. Renewable energy such as solar and wind represents lowcarbon opportunities that could replace some of these fossilsourced emissions. Today, wind and solar comprise approximately 8.4% of the electric power sector (Figure 1) which is double that of 2008. In 2018, 6.6 GW (wind) and 4.9 GW (solar) capacities were added in the U.S. while 12.9 GW of coal generating capacity was retired. Some municipalities have passed legislation encouraging a phase out of coal power plants in favor of renewables. For example, in response to the Clean Air Clean Jobs Act (CACJA) which mandates the decommissioning of coal generating power in Colorado, Xcel, the Public Service Company of Colorado closed two coal fired units in Pueblo county in 2018. Combined, the 2 plants Received: October 11, 2019 Revised: April 24, 2020 Accepted: April 24, 2020 Published: April 24, 2020 Article pubs.acs.org/est (c) 2020 American Chemical Society 6272 https:/dx.doi.org/10.1021/acs.est.9b06147 Environ. Sci. Technol. 2020, 54, 6272 6280 D ow nl oa de d vi a W O R C E ST E R P O L Y T E C H N IC I N ST o n Ju ne 5 2 02 0 at 1 1: 25 :1 1 (U T C Se e ht tp s: /p ub s. ac s. or g/ sh ar in gg ui de lin es f or o pt io ns o n ho w to le gi tim at el y sh ar e pu bl is he d ar tic le s.
author_names: Peter C Psarras

Jiajun He

Helene Pilorge

Noah McQueen

Alexander Jensen-Fellows

Kourosh Kian

Jennifer Wilcox
title: Cost Analysis of Carbon Capture and Sequestration from U.S. Natural Gas Fired Power Plants
year: 2020

abstract: BACKGROUND A high percentage of small cell lung cancer (SCLC) cases harbor cell cycle related gene mutations and RICTOR amplification. Based on underlying somatic mutations, the authors have conducted a phase 2 biomarker driven, multiarm umbrella study. METHODS The SCLC Umbrella Korea StudiES (SUKSES) is an adaptive platform trial that undergoes continual modification according to the observed outcomes. This study included 286 patients with SCLC who failed platinum therapy and who had known genomic profiles based on a predesigned screening trial. Patients with MYC amplification or CDKN2A and TP53 co alterations were allocated to adavosertib (SUKSES protocol C [SUKSES C] 7 patients) and those with RICTOR amplification were allocated to vistusertib (SUKSES D; 4 patients) Alternatively, patients who were without any predefined biomarkers were assigned to a non biomarker selected arm: adavosertib (SUKSES N1; 21 patients) or AZD2811NP (SUKSES N3; 15 patients) RESULTS Patients in the SUKSES C and SUKSES N1 arms demonstrated no objective response. Three patients presented with stable disease (SD) in SUKSES C and 6 patients in SUKSES N1. The median progression free survival (PFS) was 1.3 months (95% confidence interval, 0.9 months to not available) for SUKSES C and 1.2 months (95% CI, 1.1 1.4 months) for SUKSES N1. Patients in the SUKSES D arm demonstrated no objective response and no SD, with a PFS of 1.2 months (95% CI, 1.0 months to not available) The SUKSES N3 arm had 5 patients with SD and a PFS of 1.6 months (95% CI, 0.9 1.7 months) without an objective response. Grade>=3 adverse events (graded according to National Cancer Institute Common Terminology Criteria for Adverse Events [version 4.03] were observed as follows: 3.2% in the SUKSES C and SUKSES N1 arms and 50.0% in the SUKSES D arm. Target related neutropenia (grade>=3) was observed in approximately 60.0% of patients in the AZD2811NP arm using the current dosing schedule. CONCLUSIONS To the best of the authors' knowledge, the current study is the first biomarker driven umbrella study conducted in patients with recurrent SCLC. Although the current study demonstrated the limited clinical efficacy of monotherapy, novel biomarker approaches using other cell cycle inhibitor(s) or combinations warrant further investigation.
author_names: Sehhoon Park

Joon Ho Shim

Peter Mortimer

Simon Smith

Robert Godin

Simon J Hollingsworth

Hee-Jung Kim

Hyun Ae Jung

Jong-Mu Sun

Woong-Yang Park

Jin Seok Ahn

Myung-Ju Ahn

Se-Hoon Lee

Keunchil Park
title: Biomarker driven phase 2 umbrella trial study for patients with recurrent small cell lung cancer failing platinum based chemotherapy.
venue: Cancer
year: 2020

abstract: Identifying molecular cancer drivers is critical for precision oncology. Multiple advanced algorithms to identify drivers now exist, but systematic attempts to combine and optimize them on large datasets are few. We report a PanCancer and PanSoftware analysis spanning 9,423 tumor exomes (comprising all 33 of The Cancer Genome Atlas projects) and using 26 computational tools to catalog driver genes and mutations. We identify 299 driver genes with implications regarding their anatomical sites and cancer/cell types. Sequence and structure based analyses identified >3,400 putative missense driver mutations supported by multiple lines of evidence. Experimental validation confirmed 60% 85% of predicted mutations as likely drivers. We found that >300 MSI tumors are associated with high PD 1/PD L1, and 57% of tumors analyzed harbor putative clinically actionable events. Our study represents the most comprehensive discovery of cancer genes and mutations to date and will serve as a blueprint for future biological and clinical endeavors.
author_names: Matthew H Bailey

Collin J Tokheim

Eduard Porta-Pardo

Sohini Sengupta

Denis Bertrand

Amila Weerasinghe

Antonio Colaprico

Michael C Wendl

Jaegil Kim

Brendan Reardon

Patrick Kwok Shing Ng

Kang Jin Jeong

Song Cao

Zixing Wang

Qingsong Gao

Eric Minwei Liu

Loris Mularoni

Carlota Rubio-Perez

Niranjan Nagarajan

Isidro Cortes-Ciriano

Daniel Cui Zhou

Wen-Wei Liang

Julian M Hess

Venkata Yellapantula

David Tamborero

Abel Gonzalez-Perez

Chayaporn Suphavilai

Jia Yu Ko

Ekta Khurana

Peter J Park

Eliezer M Van Allen

Han Liang

Michael S Lawrence

Adam Godzik

Nuria Lopez-Bigas

Josh Stuart

David A Wheeler

Gad Getz

Alexander J Lazar

Gordon B Mills

Rachel Karchin

Li Ding

Samantha J Caesar-Johnson

John A Demchok

Ina Felau

Melpomeni Kasapi

Martin L Ferguson

Carolyn Hutter

Heidi J Sofia

Roy W Tarnuzzer

Zhining Wang

Liming Yang

Jean Claude Zenklusen

Jiashan (Julia) Zhang

Sudha Chudamani

Jia Liu

Laxmi Lolla

Rashi Naresh

Todd Pihl

Qiang Sun

Yunhu Wan

Ye Wu

Juok Cho

Timothy DeFreitas

Scott R Frazer

Nils Gehlenborg

David I Heiman

Pei Lin

Sam Meier

Michael S Noble

Gordon Saksena

Douglas Voet

Hailei Zhang

Brady Bernard

Nyasha Chambwe

Varsha Dhankani

Theo A Knijnenburg

Roger Kramer

Kalle Leinonen

Yuexin Liu

Michael Miller

Sheila M Reynolds

Ilya Shmulevich

Vesteinn Thorsson

Rehan Akbani

Bradley M Broom

Apurva M Hegde

Zhenlin Ju

Rupa S Kanchi

Anil Korkut

Shiyun Ling

Wenbin Liu

Kwok-Shing Ng

Arvind U K Rao

Michael Ryan

John N Weinstein

Jiexin Zhang

Adam A Abeshouse

Joshua Armenia

Debyani Chakravarty

Walid K Chatila

Ino de Bruijn

Benjamin E Gross

Zachary J Heins

Ritika Kundra

Konnor C La

Marc Ladanyi

Augustin Luna

Moriah G Nissan

Angelica Ochoa

Sarah M Phillips

Ed Reznik

Francisco Sanchez-Vega

Chris Sander

Nikolaus Schultz

Robert L Sheridan

Selcuk Onur Sumer

Yichao Sun

Barry S Taylor

Jioajiao Wang

Hongxing Zhang

Pavana Anur

Myron Peto

Paul T Spellman

Christopher C Benz

Joshua M Stuart

Christopher K Wong

Christina Yau

David Neil Hayes

Joel S Parker

Matthew D Wilkerson

Adrian Ally

Miruna Balasundaram

Reanne Bowlby

Denise Brooks

Rebecca Carlsen

Eric Chuah

Noreen Dhalla

Robert W Holt

Steven J M Jones

Katayoon Kasaian

Darlene Lee

Yussanne Ma

Marco A Marra

Michael Mayo

Richard A Moore

Andrew J Mungall

Karen L Mungall

A Gordon Robertson

Sara Sadeghi

Jacqueline E Schein

Payal Sipahimalani

Angela Tam

Nina Thiessen

Kane Tse

Tina Wong

Ashton C Berger

Rameen Beroukhim

Andrew D Cherniack

Carrie L Cibulskis

S Gabriel

Galen F Gao

Gavin Ha

Matthew L Meyerson

Steven E Schumacher

Juliann Shih

Melanie Kucherlapati

Raju Kucherlapati

Stephen Baylin

Leslie M Cope

Ludmila V Danilova

Moiz S Bootwalla

Phillip H Lai

Dennis T Maglinte

David J Van Den Berg

Daniel J Weisenberger

James T Auman

Saianand Balu

Tom Bodenheimer

Cheng Fan

Katherine A Hoadley

Alan Hoyle

Stuart R Jefferys

Corbin D Jones

Shao-Wu Meng

Piotr A Mieczkowski

Lisle E Mose

Amy H Perou

Charles M Perou

Jeffrey M Roach

Yan Shi

Janae V Simons

Tara J Skelly

Matthew G Soloway

Donghui Tan

Umadevi Veluvolu

Huihui Fan

Toshinori Hinoue

Peter W Laird

Hui Shen

Wanding Zhou

Michelle Bellair

Kyle Chang

Kyle R Covington

Chad J Creighton

Huyen Dinh

Harshavardhan Doddapaneni

Lawrence A Donehower

J Drummond

Richard A Gibbs

Robert Glenn

Walker Hale

Yi Han

Viktoriya Korchina

Sandra Lee

Lora L Lewis

Xiuping Liu

Margaret B Morgan

Donna Morton

Donna M Muzny

Jireh Santibanez

Margi Sheth

Eve Shinbrot

Liu Xi

Fengmei Zhao

Elizabeth L Appelbaum

Matthew G Cordes

Catrina C Fronick

Lucinda A Fulton

Robert S Fulton

Cyriac Kandoth

Elaine R Mardis

Michael D McLellan

Christopher A Miller

Heather K Schmidt

Richard K Wilson

Daniel Crain

Erin E Curley

Johanna Gardner

Kevin R Lau

David W Mallery

Scott Morris

Joseph D Paulauskis

Robert J Penny

Candace Shelton

Troy Shelton

Mark E Sherman

Eric M Thompson

Peggy Yena

Jay Bowen

Julie M Gastier-Foster

Mark J Gerken

Kristen M Leraas

Tara M Lichtenberg

Nilsa C Ramirez

Lisa Wise

E J Zmuda

Niall M Corcoran

Tony Costello

Christopher M Hovens

Andre Lopes Carvalho

Ana C de Carvalho

Jose H Fregnani

Adhemar Longatto-Filho

Rui Manuel Reis

Cristovam Scapulatempo-Neto

Henrique Cesar Santejo Silveira

Daniel Onofre Vidal

Andrew Burnette

Jennifer Eschbacher

Beth Hermes

Ardene Noss

Rosy Singh

Matthew L Anderson

Patricia D Castro

Michael M Ittmann

David G Huntsman

Bernard Kohl

Xuan Van Le

Richard A Thorp

Chris Andry

Elizabeth R Duffy

Vladimir K Lyadov

Oxana V Paklina

Galiya R Setdikova

Alexey Shabunin

M M Tavobilov

Christopher M McPherson

Ronald Warnick

Ross S Berkowitz

Daniel Cramer

Colleen M Feltmate

Neil Horowitz

Adam S Kibel

Michael G Muto

Chandrajit P Raut

Andrei G Malykh

Jill S Barnholtz-Sloan

Wendi Barrett

Karen Dragon Devine

Jordonna Fulop

Quinn T Ostrom

Kristen Shimmel

Yingli Wolinsky

Andrew E Sloan

Agostino Maria De Rose

Felice Giuliante

Marc T Goodman

Beth Y Karlan

Curt H Hagedorn

John Eckman

Jodi Harr

Jerome B Myers

Kelinda Tucker

Leigh Anne Zach

Brenda Deyarmin

Hai Hu

Leonid Kvecher

Caroline Larson

Richard J Mural

S B Somiari

Ales Vicha

Tomas Zelinka

Joseph Bennett

Mary V Iacocca

Brenda Rabeno

Patricia Swanson

Mathieu Latour

Louis Lacombe

Bernard Tetu

Alain Bergeron

Mary McGraw

Susan M Staugaitis

John A Chabot

Hanina Hibshoosh

Antonia Sepulveda

Tao Su

Timothy Wang

Olga Potapova

Olga Voronina

Laurence Desjardins

Odette Mariani

Sergio Roman-Roman

Xavier Sastre

Marc-Henri Stern

Feixiong Cheng

Sabina Signoretti

Andrew Berchuck

Darell Bigner

Eric S Lipp

Jeffrey R Marks

Shannon J McCall

Roger R McLendon

Angeles Alvarez Secord

Alexis Sharp

Madhusmita Behera

Daniel J Brat

Amy Y Chen

Keith A Delman

Seth Daniel Force

Fadlo R Khuri

Kelly R Magliocca

Shishir K Maithel

Jeffrey J Olson

Taofeek Kunle Owonikoko

Alan Pickens

Suresh R Ramalingam

Gabriel L Sica

Hong-zhen Zhang

Wil Eijckenboom

Ad Gillis

Esther Korpershoek

Leendert H J Looijenga

Wolter J Oosterhuis

Hans Stoop

Kim E M van Kessel

Ellen C Zwarthoff

Chiara Calatozzolo

Lucia Cuppini

Stefania Cuzzubbo

Francesco DiMeco

Gaetano Finocchiaro

Luca Mattei

Alessandro Perin

Bianca Pollo

Chu Chen

John R Houck

Pawadee Lohavanichbutr

Arndt Hartmann

Christine G Stoehr

Robert Stoehr

Helge Taubert

Sven Wach

Bernd Wullich

Witold Kycler

Dawid Murawa

Maciej Wiznerowicz

K J Kwon Chung

William Jeffery Edenfield

Julie M Martin

Eric Baudin

Glenn J Bubley

Raphael Bueno

Assunta De Rienzo

William G Richards

Steven N Kalkanis

Tom Mikkelsen

Houtan Noushmehr

Lisa Scarpace

Nicolas Girard

Marta Aymerich

Elias Campo

Eva Gine

Armando Lopez Guillermo

Nguyen Van Bang

Phan Thi Hong Hanh

Bui Duc Phu

Yufang Tang

Howard Colman

Kimberley J Evason

Peter R Dottino

John A Martignetti

Hani Gabra

Hartmut Juhl

Teniola Akeredolu

Serghei Stepa

Dave S B Hoon

Keun-Young Ahn

Koo Jeong Kang

Felix Beuschlein

Anne C Breggia

Michael J Birrer

Deborah Bell

Mitesh J Borad

Alan H Bryce

Erik Castle

Vishal Chandan

John Cheville

John A Copland

Michael B Farnell

Thomas Flotte

Nasra H Giama

Thai H Ho

Michael J Kendrick

Jean-Pierre A Kocher

Karla J Kopp

Catherine D Moser

David M Nagorney

Daniel R O'Brien

Brian P O'neill

Tushar Patel

Gloria M Petersen

Florencia G Que

Michael Rivera

Lewis R Roberts

Robert Christian Smallridge

Thomas C Smyrk

Melissa L Stanton

R Houston Thompson

Michael S Torbenson

Ju Dong Yang

Lizhi Zhang

Fadi Brimo

Jaffer A Ajani

Ana Maria Angulo Gonzalez

Carmen Behrens

Jolanta E Bondaruk

Russell Broaddus

Bogdan A Czerniak

Bita Esmaeli

Junya Fujimoto

Jeffrey E Gershenwald

Charles Chuanhai Guo

Christopher L Logothetis

Funda Meric-Bernstam

Cesar A Moran

Lois M Ramondetta

David Rice

Anil K Sood

Pheroze Tamboli

Timothy Thompson

Patricia Troncoso

Anne S Tsao

Ignacio I Wistuba

Candace D Carter

Lauren E Haydu

Peter Hersey

Valerie Jakrot

Hojabr Kakavand

Richard F Kefford

Kenneth Lee

Georgina V Long

Graham Mann

Michael Cj Quinn

Robyn P M Saw

Richard A Scolyer

Kerwin F Shannon

Andrew J Spillane

Jonathan Stretch

Maria Synott

John Ryan Thompson

James S Wilmott

Hikmat A Al-Ahmadie

Timothy A Chan

Ronald A Ghossein

Anuradha Gopalan

Douglas A Levine

Victor Reuter

Samuel Singer

Bhuvanesh Singh

Nguyen Viet Tien

Thomas B Broudy

Cyrus Mirsaidi

Praveen Nair

Paul Drwiega

Judy Miller

Jennifer Smith

Howard A Zaren

Joong-Won Park

Nguyen Phi Hung

Electron Kebebew

W Marston Linehan

Adam R Metwalli

Karel Pacak

Peter A Pinto

Mark Schiffman

Laura S Schmidt

Cathy D Vocke

Nicolas Wentzensen

Robert A Worrell

Hannah P Yang

Marc D S Moncrieff

Chandra Goparaju

Jonathan Melamed

Harvey I Pass

Natalia Botnariuc

Irina Caraman

Mircea Cernat

Inga Chemencedji

Adrian Clipca

Serghei Doruc

Ghenadie Gorincioi

Sergiu Mura

Maria Pirtac

Irina Stancul

Diana Tcaciuc

Monique Albert

Iakovina Alexopoulou

Angel Arnaout

John M S Bartlett

Jay Engel

Sebastien Gilbert

Jeremy R Parfitt

Harmandeep Singh Sekhon

George V Thomas

Doris M Rassl

Robert Campbell Rintoul

Carlo B Bifulco

Raina A Tamakawa

Walter J Urba

Nicholas Hayward

Henri J L M Timmers

Anna Antenucci

Francesco Facciolo

Gian Luca Grazi

Mirella Marino

Roberta Merola

Ronald R de Krijger

Anne-Paule Gimenez-Roqueplo

Alain Piche

Simone Chevalier

Ginette McKercher

Kivanc Birsoy

Gene H Barnett

Cathy Brewer

Carol F Farver

Theresa Naska

Nathan A Pennell

Daniel Raymond

Cathy Schilero

Kathy Smolenski

Felicia Williams

Carl D Morrison

Jeffrey A Borgia

Michael J Liptay

Mark D Pool

Christopher W Seder

Kerstin Junker

Larsson Omberg

Mikhail Dinkin

George Manikhas

Domenico Alvaro

Maria Consiglia Bragazzi

Vincenzo Cardinale

Guido Carpino

Eugenio Gaudio

David W Chesla

Sandra L Cottingham

Michael V Dubina

Fedor Vladimirovich Moiseenko

Renumathy Dhanasekaran

Karl Friedrich Becker

Klaus-Peter Janssen

Julia Slotta-Huspenina

Mohamed H Abdel-Rahman

Dina Aziz

Sue Bell

Colleen M Cebulla

Amy Davis

Rebecca Duell

J Bradley Elder

Joe Hilty

Bahavna Kumar

James Lang

Norman L Lehman

Randy Mandt

Phuong T L Nguyen

Robert Pilarski

Karan Rai

Lynn R Schoenfield

Kelly Senecal

Paul E Wakely

Paul Daniel Hansen

Ronald Lechan

James Powers

Arthur S Tischler

William E Grizzle

Katherine C Sexton

Alison Kastl

Joel M Henderson

Sima P Porten

Jens Waldmann

Martin Fassnacht

Sylvia L Asa

Dirk Schadendorf

Marta Couce

Markus Graefen

Hartwig Huland

Guido Sauter

Thorsten Schlomm

Ronald Simon

Pierre Tennstedt

Oluwole Olabode

Mark Nelson

Oliver F Bathe

Peter R Carroll

June M Chan

Philip John Disaia

Pat Glenn

Robin Kate Kelley

Charles N Landen

Joanna J Phillips

M Prados

Jeffry P Simko

Karen Smith-McCune

Scott VandenBerg

Kevin King Roggin

Ashley Fehrenbach

Ady Kendler

Suzanne Sifri

Ruth Steele

Antonio Jimeno

Francis A Carey

Ian M Forgie

Massimo Mannelli

Michael E Carney

Brenda Hernandez

Benito Campos

Christel Herold-Mende

Christine Jungk

Andreas Unterberg

Andreas von Deimling

Aaron Bossler

Joseph A Galbraith

Laura Jacobus

Michael C Knudson

Tina M Knutson

Deqin Ma

Mohammed M Milhem

Rita Sigmund

Andrew K Godwin

Rashna Madan

Howard G Rosenthal

Clement A Adebamowo

Sally N Adebamowo

Alex Boussioutas

David G Beer

Thomas J Giordano

Anne-Marie Mes-Masson

Fred Saad

Therese Bocklage

Lisa Michelle Landrum

Robert S Mannel

Kathleen Moore

Katherine M Moxley

Russell Postier

Joan L Walker

Rosemary Zuna

Michael Feldman

Federico Valdivieso

Rajiv Dhir

James D Luketich

Edna M Mora Pinero

Mario E Quintero-Aguilo

Carlos Gilberto Carlotti

Jose Sebastiao Dos Santos

Rafael Kemp

Ajith Sankarankuty

Daniela Tirapelli

James W F Catto

Kathy J Agnew

Elizabeth M Swisher

Jenette Creaney

Bruce Robinson

Carl S Shelley

Eryn M Godwin

Sara Kendall

Cassaundra Shipman

Carol R Bradford

Thomas E Carey

Andrea Haddad

Jeff Moyer

Lisa A Peterson

Mark Prince

Laura S Rozek

Gregory T Wolf

Rayleen V Bowman

Kwun M Fong

Ian Yang

Robert J Korst

W Kimryn Rathmell

J Leigh Fantacone-Campbell

Jeffrey Hooke

Albert J Kovatich

Craig D Shriver

John F Dipersio

Bettina F Drake

Ramaswamy Govindan

Sharon E Heath

Timothy J Ley

Brian A Van Tine

Peter Westervelt

Mark A Rubin

Jung Il Lee

Natalia D Aredes

Armaz Mariamidze
title: Comprehensive Characterization of Cancer Driver Genes and Mutations
venue: Cell
year: 2018

abstract: BACKGROUND D2 gastrectomy is recommended in US and European guidelines, and is preferred in east Asia, for patients with resectable gastric cancer. Adjuvant chemotherapy improves patient outcomes after surgery, but the benefits after a D2 resection have not been extensively investigated in large scale trials. We investigated the effect on disease free survival of adjuvant chemotherapy with capecitabine plus oxaliplatin after D2 gastrectomy compared with D2 gastrectomy only in patients with stage II IIIB gastric cancer. METHODS The capecitabine and oxaliplatin adjuvant study in stomach cancer (CLASSIC) study was an open label, parallel group, phase 3, randomised controlled trial undertaken in 37 centres in South Korea, China, and Taiwan. Patients with stage II IIIB gastric cancer who had had curative D2 gastrectomy were randomly assigned to receive adjuvant chemotherapy of eight 3 week cycles of oral capecitabine (1000 mg/m(2) twice daily on days 1 to 14 of each cycle) plus intravenous oxaliplatin (130 mg/m(2) on day 1 of each cycle) for 6 months or surgery only. Block randomisation was done by a central interactive computerised system, stratified by country and disease stage. Patients, and investigators giving interventions, assessing outcomes, and analysing data were not masked. The primary endpoint was 3 year disease free survival, analysed by intention to treat. This study reports a prespecified interim efficacy analysis, after which the trial was stopped after a recommendation by the data monitoring committee. The trial is registered at ClinicalTrials.gov (NCT00411229) FINDINGS 1035 patients were randomised (520 to receive chemotherapy and surgery, 515 surgery only) Median follow up was 34*2 months (25*4 41*7) in the chemotherapy and surgery group and 34*3 months (25*6 41*9) in the surgery only group. 3 year disease free survival was 74% (95% CI 69 79) in the chemotherapy and surgery group and 59% (53 64) in the surgery only group (hazard ratio 0*56, 95% CI 0*44 0*72; p<0*0001) Grade 3 or 4 adverse events were reported in 279 of 496 patients (56% in the chemotherapy and surgery group and in 30 of 478 patients (6% in the surgery only group. The most common adverse events in the intervention group were nausea (n=326) neutropenia (n=300) and decreased appetite (n=294) INTERPRETATION Adjuvant capecitabine plus oxaliplatin treatment after curative D2 gastrectomy should be considered as a treatment option for patients with operable gastric cancer. FUNDING F Hoffmann La Roche and Sanofi Aventis.
author_names: Yung-Jue Bang

Young-Woo Kim

Han-Kwang Yang

Hyun Cheol Chung

Young-Kyu Park

Kyung Hee Lee

Keun-Wook Lee

Yong Ho Kim

Sang-Ik Noh

Jae Yong Cho

Young-jae Mok

Yeul-Hong Kim

Jiafu Ji

Ta-Sen Yeh

Peter Button

Florin Sirzen

Sung Hoon Noh
title: Adjuvant capecitabine and oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC) a phase 3 open label, randomised controlled trial
venue: The Lancet
year: 2012

abstract: Jeeyun Lee1, Seung Tae Kim1, Kyung Kim1, Hyuk Lee2, Iwanka Kozarewa3, Peter G.S. Mortimer4, Justin I. Odegaard5, Elizabeth A. Harrington3, Juyoung Lee1, Taehyang Lee1, Sung Yong Oh6, Jung Hun Kang7, Jung Hoon Kim8, Youjin Kim9, Jun Ho Ji9, Young Saing Kim10, Kyoung Eun Lee11, Jinchul Kim1, Tae Sung Sohn12, Ji Yeong An12, Min Gew Choi12, Jun Ho Lee12, Jae Moon Bae12, Sung Kim12, Jae J. Kim2, Yang Won Min2, Byung Hoon Min2, Nayoung K.D. Kim13,4, Sally Luke3, Young Hwa Kim4, Jung Yong Hong1, Se Hoon Park1, Joon Oh Park1, Young Suk Park1, Ho Yeong Lim1, AmirAli Talasaz5, Simon J. Hollingsworth14, Kyoung Mee Kim15, and Won Ki Kang1 RESEARCH ARTICLE
author_names: Jeeyun Lee

Seung Tae Kim

Kyung Bo Kim

Hyuk Joon Lee

Iwanka Kozarewa

Peter Mortimer

Justin I Odegaard

Elizabeth A Harrington

Juyoung Lee

Sung Yong Oh

Jung Hun Kang

Jung Hoon Kim

Youjin Kim

Jun Ho Ji

Kyoung Eun Lee

Jinchul Kim

Tae Sung Sohn

Ji Yeong An

Min Gew Choi

Jun Ho Lee

Jae Moon Bae

Jae J Kim

Yang Won Min

Byung-Hoon Min

Nayoung K D Kim

Sally Luke

Jung Yong Hong

Se Hoon Park

Joon-Oh Park

Young Suk Park

Ho Yeong Lim

A Talasaz

Simon J Hollingsworth

Kyoung-Mee Kim

Won Ki Kang
title: Tumor Genomic Profiling Guides Patients with Metastatic Gastric Cancer to Targeted Treatment: The VIKTORY Umbrella Trial
year: 2019

abstract: DOI: 10.1002/admi.201900607 energy (IE) or electron affinity (EA) respectively, of the OSC. The precise work function required depends on the injection resistance that can be tolerated, but the threshold for ohmic transition lies well beyond the onset of Fermi level pinning.[2] For making hole contacts, air stable hole doped conducting polymers with work functions of up to 5.2 eV, such as poly(3,4 ethylenedioxythiophene):poly (styrenesulfonic acid) (PEDT:PSSH)[3] and sulfonated poly(thiophene 3 [2 (2 methoxyethoxy)ethoxy] 2,5 diyl):poly(4 hydroxystyrene) (S P3MEET:PHOST)[4] have long been available. For making electron contacts, however, stable electron doped conducting polymers with work functions smaller than 4.0 eV are not available because of vulnerability to oxygen reduction reaction.[5] Various schemes have thus been devised to fabricate electron doped semiconductor electron transport/injection layers,[6] including the use of multivalent anions as latent electron donors[7] with the selfcompensated polymer platform which allow heavily doped conducting polymers to be obtained over a wide range of work functions, free from the problem of "dopant migration."[8] The ability to make ohmic contacts at will, in particular to the more challenging high IE and low EA semiconductors, is important for continued advancement in the field. Recently, polyethylenimine (PEI) polyethylenimine (ethoxylated) (PEIE) and related polymers, and even amine solvents,[9] have been suggested to greatly improve electron injection when applied to various surfaces, including metals, metal oxides, and PEDT:PSSH.[10] However, PEI and PEIE are both electronic insulators, so this result is puzzling. Careful recent work has shown that their thin interlayers indeed act as tunnel barriers, not ohmic electron contacts; they confine holes injected from the opposite contact to induce an electric field realignment improving electron injection, but far away from ohmic regime.[11] This mechanism is the same as that demonstrated some time ago through the use of layer by layer assembled monolayers to confine carriers in organic light emitting diodes.[12,13] The large 1 eV work function reduction generated by the PEI or PEIE interlayers is thus essentially futile. Their electron contacts are nonohmic, despite their low work functions.[14] This is not surprising. It has been well established It is well known that thin polyethylenimine and polyethylenimine (ethoxylated) (PEIE) layers can reduce the work function of metals, metal oxides, and conducting polymers by 1 eV or more through an interface dipole, but this is not generally sufficient to produce an ohmic electron contact. Here, it is shown that a short, positive bias preconditioning can switch the injection characteristics of a self assembled monolayer of PEIE on poly(3,4 ethyl ene dioxythiophene):poly(styrenesulfonic acid) (PEDT:PSSH) from electronblocking to electron injecting into poly(N,N' bis(2 octyldodecyl) 1,4,5,8naphthalenebis(dicarboxy imide) 2,6 diyl) alt (2,2' bithiophene) 5,5' diyl) Despite its low work function (4.0 eV) and favorable energy level alignment, the PEIE modified contact is initially blocking because the tunneling barrier limits carrier accumulation. The prebias boosts this accumulation density through an interfacial solid state electrochemical process that positively charges the PEIE, which induces charge compensation by mobile electron carriers in the adjacent semiconductor layer through the field effect. This mechanism to trigger the ohmic transition appears to be general, as similar effects, albeit to a small extent, is found in semiconductors with even smaller electron affinity. This is the first example of ohmic electron injection from PEDT:PSSH into an organic semiconductor, which would be useful for fabricating tandem and other cells.
author_names: Chao Zhao

Adrian Nugraha Utama

Kim-Kian Choo

Lay-Lay Chua

Rui-Qi Png

Peter K H Ho
title: Bias Induced Electrochemical Electron Doping of Organic Semiconductor Contacts
venue: Advanced Materials Interfaces
year: 2019

abstract: Genetic alterations in signaling pathways that control cell cycle progression, apoptosis, and cell growth are common hallmarks of cancer, but the extent, mechanisms, and co occurrence of alterations in these pathways differ between individual tumors and tumor types. Using mutations, copy number changes, mRNA expression, gene fusions and DNA methylation in 9,125 tumors profiled by The Cancer Genome Atlas (TCGA) we analyzed the mechanisms and patterns of somatic alterations in ten canonical pathways: cell cycle, Hippo, Myc, Notch, Nrf2, PI 3 Kinase/Akt, RTK RAS, TGFb signaling, p53 and b catenin/Wnt. We charted the detailed landscape of pathway alterations in 33 cancer types, stratified into 64 subtypes, and identified patterns of co occurrence and mutual exclusivity. Eighty nine percent of tumors had at least one driver alteration in these pathways, and 57% percent of tumors had at least one alteration potentially targetable by currently available drugs. Thirty percent of tumors had multiple targetable alterations, indicating opportunities for combination therapy.
author_names: Francisco Sanchez-Vega

Marco Mina

Joshua Armenia

Walid K Chatila

Augustin Luna

Konnor C La

Sofia Dimitriadoy

David L Liu

Havish S Kantheti

Sadegh Saghafinia

Debyani Chakravarty

Foysal Daian

Qingsong Gao

Matthew H Bailey

Wen-Wei Liang

Steven M Foltz

Ilya Shmulevich

Li Ding

Zachary J Heins

Angelica Ochoa

Benjamin E Gross

Hongxing Zhang

Ritika Kundra

Cyriac Kandoth

Istemi Bahceci

Leonard Dervishi

Ugur Dogrusoz

Wanding Zhou

Hui Shen

Peter W Laird

Gregory P Way

Casey S Greene

Han Liang

Yonghong Xiao

Chen Wang

Antonio Iavarone

Alice H Berger

Trever G Bivona

Alexander J Lazar

Gary D Hammer

Thomas J Giordano

Lawrence N Kwong

Grant A McArthur

Aaron D Tward

Mitchell J Frederick

Frank McCormick

Matthew L Meyerson

Eliezer M Van Allen

Andrew D Cherniack

Giovanni Ciriello

Chris Sander

Nikolaus Schultz

Samantha J Caesar-Johnson

John A Demchok

Ina Felau

Melpomeni Kasapi

Martin L Ferguson

Carolyn Hutter

Heidi J Sofia

Roy W Tarnuzzer

Zhining Wang

Liming Yang

Jean Claude Zenklusen

Jiashan (Julia) Zhang

Sudha Chudamani

Jia Liu

Laxmi Lolla

Rashi Naresh

Todd Pihl

Qiang Sun

Yunhu Wan

Ye Wu

Juok Cho

Timothy DeFreitas

Scott R Frazer

Nils Gehlenborg

Gad Getz

David I Heiman

Jaegil Kim

Michael S Lawrence

Pei Lin

Sam Meier

Michael S Noble

Gordon Saksena

Douglas Voet

Hailei Zhang

Brady Bernard

Nyasha Chambwe

Varsha Dhankani

Theo A Knijnenburg

Roger Kramer

Kalle Leinonen

Yuexin Liu

Michael Miller

Sheila M Reynolds

Vesteinn Thorsson

Rehan Akbani

Bradley M Broom

Apurva M Hegde

Zhenlin Ju

Rupa S Kanchi

Anil Korkut

Shiyun Ling

Wenbin Liu

Gordon B Mills

Kwok-Shing Ng

Arvind U K Rao

Michael J Ryan

John N Weinstein

Jiexin Zhang

Adam A Abeshouse

Ino de Bruijn

Marc Ladanyi

Moriah G Nissan

Sarah M Phillips

Ed Reznik

Robert L Sheridan

Selcuk Onur Sumer

Yichao Sun

Barry S Taylor

Jioajiao Wang

Pavana Anur

Myron Peto

Paul T Spellman

Christopher C Benz

Joshua M Stuart

Christopher K Wong

Christina Yau

David Neil Hayes

Joel S Parker

Matthew D Wilkerson

Adrian Ally

Miruna Balasundaram

Reanne Bowlby

Denise Brooks

Rebecca Carlsen

Eric Chuah

Noreen Dhalla

Robert W Holt

Steven J M Jones

Katayoon Kasaian

Darlene Lee

Yussanne Ma

Marco A Marra

Michael Mayo

Richard A Moore

Andrew J Mungall

Karen L Mungall

A Gordon Robertson

Sara Sadeghi

Jacqueline E Schein

Payal Sipahimalani

Angela Tam

Nina Thiessen

Kane Tse

Tina Wong

Ashton C Berger

Rameen Beroukhim

Carrie L Cibulskis

S Gabriel

Galen F Gao

Gavin Ha

Steven E Schumacher

Juliann Shih

Melanie Kucherlapati

Raju Kucherlapati

Stephen Baylin

Leslie M Cope

Ludmila V Danilova

Moiz S Bootwalla

Phillip H Lai

Dennis T Maglinte

David J Van Den Berg

Daniel J Weisenberger

James T Auman

Saianand Balu

Tom Bodenheimer

Cheng Fan

Katherine A Hoadley

Alan Hoyle

Stuart R Jefferys

Corbin D Jones

Shao-Wu Meng

Piotr A Mieczkowski

Lisle E Mose

Amy H Perou

Charles M Perou

Jeffrey M Roach

Yan Shi

Janae V Simons

Tara J Skelly

Matthew G Soloway

Donghui Tan

Umadevi Veluvolu

Huihui Fan

Toshinori Hinoue

Michelle Bellair

Kyle Chang

Kyle R Covington

Chad J Creighton

Huyen Dinh

Harshavardhan Doddapaneni

Lawrence A Donehower

J Drummond

Richard A Gibbs

Robert Glenn

Walker Hale

Yi Han

Viktoriya Korchina

Sandra Lee

Lora L Lewis

Xiuping Liu

Margaret B Morgan

Donna Morton

Donna M Muzny

Jireh Santibanez

Margi Sheth

Eve Shinbrot

David A Wheeler

Liu Xi

Fengmei Zhao

Julian M Hess

Elizabeth L Appelbaum

Matthew G Cordes

Catrina C Fronick

Lucinda A Fulton

Robert S Fulton

Elaine R Mardis

Michael D McLellan

Christopher A Miller

Heather K Schmidt

Richard K Wilson

Daniel Crain

Erin E Curley

Johanna Gardner

Kevin R Lau

David W Mallery

Scott Morris

Joseph D Paulauskis

Robert J Penny

Candace Shelton

Troy Shelton

Mark E Sherman

Eric M Thompson

Peggy Yena

Jay Bowen

Julie M Gastier-Foster

Mark J Gerken

Kristen M Leraas

Tara M Lichtenberg

Nilsa C Ramirez

Lisa Wise

E J Zmuda

Niall M Corcoran

Tony Costello

Christopher M Hovens

Andre Lopes Carvalho

Ana C de Carvalho

Jose H Fregnani

Adhemar Longatto-Filho

Rui Manuel Reis

Cristovam Scapulatempo-Neto

Henrique Cesar Santejo Silveira

Daniel Onofre Vidal

Andrew Burnette

Jennifer Eschbacher

Beth Hermes

Ardene Noss

Rosy Singh

Matthew L Anderson

Patricia D Castro

Michael M Ittmann

David G Huntsman

Bernard Kohl

Xuan Van Le

Richard A Thorp

Chris Andry

Elizabeth R Duffy

Vladimir K Lyadov

Oxana V Paklina

Galiya R Setdikova

Alexey Shabunin

M M Tavobilov

Christopher M McPherson

Ronald E Warnick

Ross S Berkowitz

Daniel Cramer

Colleen M Feltmate

Neil Horowitz

Adam S Kibel

Michael G Muto

Chandrajit P Raut

A P Malykh

Jill S Barnholtz-Sloan

Wendi Barrett

Karen Dragon Devine

Jordonna Fulop

Quinn T Ostrom

Kristen Shimmel

Yingli Wolinsky

Andrew E Sloan

Agostino Maria De Rose

Felice Giuliante

Marc T Goodman

Beth Y Karlan

Curt H Hagedorn

John Eckman

Jodi Harr

Jerome B Myers

Kelinda Tucker

Leigh Anne Zach

Brenda Deyarmin

Hai Hu

Leonid Kvecher

Caroline Larson

Richard J Mural

S B Somiari

Ales Vicha

Tomas Zelinka

Joseph Bennett

Mary V Iacocca

Brenda Rabeno

Patricia Swanson

Mathieu Latour

Louis Lacombe

Bernard Tetu

Alain Bergeron

Mary McGraw

Susan M Staugaitis

John Chabot

Hanina Hibshoosh

Antonia Sepulveda

Tao Su

Timothy Wang

Olga Potapova

Olga Voronina

Laurence Desjardins

Odette Mariani

Sergio Roman-Roman

Xavier Sastre

Marc-Henri Stern

Feixiong Cheng

Sabina Signoretti

Andrew Berchuck

Darell D Bigner

Eric S Lipp

Jeffrey R Marks

Shannon J McCall

Roger R McLendon

Angeles Alvarez Secord

Alexis Sharp

Madhusmita Behera

Daniel J Brat

Amy Y Chen

Keith A Delman

Seth Daniel Force

Fadlo R Khuri

Kelly R Magliocca

Shishir K Maithel

Jeffrey J Olson

Taofeek Kunle Owonikoko

Alan Pickens

Suresh R Ramalingam

Gabriel L Sica

Hong-zhen Zhang

Wil Eijckenboom

Ad Gillis

Esther Korpershoek

Leendert H J Looijenga

Wolter J Oosterhuis

Hans Stoop

Kim E M van Kessel

Ellen C Zwarthoff

Chiara Calatozzolo

Lucia Cuppini

Stefania Cuzzubbo

Francesco DiMeco

Gaetano Finocchiaro

Luca Mattei

Alessandro Perin

Bianca Pollo

Chu Chen

John R Houck

Pawadee Lohavanichbutr

Arndt Hartmann

Christine G Stoehr

Robert Stoehr

Helge Taubert

Sven Wach

Bernd Wullich

Witold Kycler

Dawid Murawa

Maciej Wiznerowicz

K J Kwon Chung

William Jeffery Edenfield

Julie M Martin

Eric Baudin

Glenn J Bubley

Raphael Bueno

Assunta De Rienzo

William G Richards

Steven N Kalkanis

Tom Mikkelsen

Houtan Noushmehr

Lisa Scarpace

Nicolas Girard

Marta Aymerich

Elias Campo

Eva Gine

Armando Lopez Guillermo

Nguyen Van Bang

Phan Thi Hong Hanh

Bui Duc Phu

Yufang Tang

Howard Colman

Kimberley J Evason

Peter R Dottino

John A Martignetti

Hani Gabra

Hartmut Juhl

Teniola Akeredolu

Serghei Stepa

Dave S B Hoon

Keun-Young Ahn

Koo Jeong Kang

Felix Beuschlein

Anne C Breggia

Michael Birrer

Deborah Bell

Mitesh J Borad

Alan H Bryce

Erik Castle

Vishal Chandan

John Cheville

John A Copland

Michael B Farnell

Thomas Flotte

Nasra H Giama

Thai H Ho

Michael J Kendrick

Jean-Pierre A Kocher

Karla J Kopp

Catherine D Moser

David M Nagorney

Daniel R O'Brien

Brian P O'neill

Tushar Patel

Gloria M Petersen

Florencia G Que

Michael Rivera

Lewis R Roberts

Robert Christian Smallridge

Thomas C Smyrk

Melissa L Stanton

R Houston Thompson

Michael S Torbenson

Ju Dong Yang

Lizhi Zhang

Fadi Brimo

Jaffer A Ajani

Ana Maria Angulo Gonzalez

Carmen Behrens

Jolanta E Bondaruk

Russell Broaddus

Bogdan A Czerniak

Bita Esmaeli

Junya Fujimoto

Jeffrey E Gershenwald

Charles Chuanhai Guo

Christopher L Logothetis

Funda Meric-Bernstam

Cesar Moran

Lois M Ramondetta

David Rice

Anil K Sood

Pheroze Tamboli

Timothy Thompson

Patricia Troncoso

Anne S Tsao

Ignacio I Wistuba

Candace D Carter

Lauren E Haydu

Peter Hersey

Valerie Jakrot

Hojabr Kakavand

Richard F Kefford

Kenneth Lee

Georgina V Long

Graham Mann

Michael Cj Quinn

Robyn P M Saw

Richard A Scolyer

Kerwin F Shannon

Andrew J Spillane

Jonathan Stretch

Maria Synott

John Ryan Thompson

James S Wilmott

Hikmat A Al-Ahmadie

Timothy A Chan

Ronald A Ghossein

Anuradha Gopalan

Douglas A Levine

Victor Reuter

Samuel Singer

Bhuvanesh Singh

Nguyen Viet Tien

Thomas B Broudy

Cyrus Mirsaidi

Praveen Nair

Paul Drwiega

Judy Miller

Jennifer Smith

Howard A Zaren

Joong-Won Park

Nguyen Phi Hung

Electron Kebebew

W Marston Linehan

Adam R Metwalli

Karel Pacak

Peter A Pinto

Mark Schiffman

Laura S Schmidt

Cathy D Vocke

Nicolas Wentzensen

Robert A Worrell

Hannah P Yang

Marc Moncrieff

Chandra Goparaju

Jonathan Melamed

Harvey I Pass

Natalia Botnariuc

Irina Caraman

Mircea Cernat

Inga Chemencedji

Adrian Clipca

Serghei Doruc

Ghenadie Gorincioi

Sergiu Mura

Maria Pirtac

Irina Stancul

Diana Tcaciuc

Monique Albert

Iakovina Alexopoulou

Angel Arnaout

John M S Bartlett

Jay Engel

Sebastien Gilbert

Jeremy R Parfitt

Harmandeep Singh Sekhon

George V Thomas

Doris M Rassl

Robert Campbell Rintoul

Carlo B Bifulco

Raina A Tamakawa

Walter J Urba

Nicholas Hayward

Henri J L M Timmers

Anna Antenucci

Francesco Facciolo

Gian Luca Grazi

Mirella Marino

Roberta Merola

Ronald R de Krijger

Anne-Paule Gimenez-Roqueplo

Alain Piche

Simone Chevalier

Ginette McKercher

Kivanc Birsoy

Gene H Barnett

Cathy Brewer

Carol F Farver

Theresa Naska

Nathan A Pennell

Daniel Raymond

Cathy Schilero

Kathy Smolenski

Felicia Williams

Carl D Morrison

Jeffrey A Borgia

Michael J Liptay

Mark D Pool

Christopher W Seder

Kerstin Junker

Larsson Omberg

Mikhail Dinkin

George Manikhas

Domenico Alvaro

Maria Consiglia Bragazzi

Vincenzo Cardinale

Guido Carpino

Eugenio Gaudio

David W Chesla

Sandra L Cottingham

Michael V Dubina

Fedor Vladimirovich Moiseenko

Renumathy Dhanasekaran

Karl Friedrich Becker

Klaus-Peter Janssen

Julia Slotta-Huspenina

Mohamed H Abdel-Rahman

Dina Aziz

Sue Bell

Colleen M Cebulla

Amy Davis

Rebecca Duell

J Bradley Elder

Joe Hilty

Bahavna Kumar

James Lang

Norman L Lehman

Randy Mandt

Phuong T L Nguyen

Robert Pilarski

Karan Rai

Lynn R Schoenfield

Kelly Senecal

Paul E Wakely

Paul Daniel Hansen

Ronald Lechan

James Powers

Arthur S Tischler

William E Grizzle

Katherine C Sexton

Alison Kastl

Joel Henderson

Sima P Porten

Jens Waldmann

Martin Fassnacht

Sylvia L Asa

Dirk Schadendorf

Marta Couce

Markus Graefen

Hartwig Huland

Guido Sauter

Thorsten Schlomm

Ronald Simon

Pierre Tennstedt

Oluwole Olabode

Mark Nelson

Oliver F Bathe

Peter R Carroll

June M Chan

Philip John Disaia

Pat Glenn

Robin Kate Kelley

Charles N Landen

Joanna J Phillips

M Prados

Jeffry P Simko

Karen Smith-McCune

Scott L Vandenberg

Kevin King Roggin

Ashley Fehrenbach

Ady Kendler

Suzanne Sifri

Ruth Steele

Antonio Jimeno

Francis A Carey

Ian M Forgie

Massimo Mannelli

Michael E Carney

Brenda Hernandez

Benito Campos

Christel Herold-Mende

Christine Jungk

Andreas Unterberg

Andreas von Deimling

Aaron D Bossler

Joseph A Galbraith

Laura Jacobus

Michael C Knudson

Tina M Knutson

Deqin Ma

Mohammed M Milhem

Rita D Sigmund

Andrew K Godwin

Rashna Madan

Howard G Rosenthal

Clement A Adebamowo

Sally N Adebamowo

Alex Boussioutas

David G Beer

Anne-Marie Mes-Masson

Fred Saad

Therese Bocklage

Lisa Michelle Landrum

Robert S Mannel

Kathleen Moore

Katherine M Moxley

Russell Postier

Joan L Walker

Rosemary Zuna

Michael Feldman

Federico Valdivieso

Rajiv Dhir

James D Luketich

Edna M Mora Pinero

Mario E Quintero-Aguilo

Carlos Gilberto Carlotti

Jose Sebastiao Dos Santos

Rafael Kemp

Ajith Sankarankuty

Daniela Tirapelli

James W F Catto

Kathy J Agnew

Elizabeth M Swisher

Jenette Creaney

Bruce Robinson

Carl S Shelley

Eryn M Godwin

Sara Kendall

Cassaundra Shipman

Carol R Bradford

Thomas E Carey

Andrea Haddad

Jeff Moyer

Lisa A Peterson

Mark Prince

Laura S Rozek

Gregory Wolf

Rayleen V Bowman

Kwun M Fong

Ian Yang

Robert J Korst

W Kimryn Rathmell

J Leigh Fantacone-Campbell

Jeffrey Hooke

Albert J Kovatich

Craig D Shriver

John F Dipersio

Bettina F Drake

Ramaswamy Govindan

Sharon E Heath

Timothy J Ley

Brian A Van Tine

Peter Westervelt

Mark A Rubin

Jung Il Lee

Natalia D Aredes

Armaz Mariamidze
title: Oncogenic Signaling Pathways in The Cancer Genome Atlas
venue: Cell
year: 2018