Title: 笹井芳樹 (Yoshiki Sasai)
Section: 研究業績
Subsection: 主な原著論文

Sasai, Y., Lu, B., Steinbeisser, H., Geissert, D., Gont, L.K., De Robertis, E.M. (1994). “Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes”. Cell 79 (5):  779-790. https://doi.org/10.1016/0092-8674(94)90068-X. Piccolo, S., Sasai, Y., Lu, B. and De Robertis, E.M. (1996). “Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of Chordin to BMP-4”. Cell 86:  589-598. PMID 8752213. E. M. De Robertis, Yoshiki Sasai (1996). “A common plan for dorsoventral patterning in Bilateria”. Nature 380:  37-40. https://doi.org/10.1038/380037a0. Morizane A, Takahashi J, Takagi Y, Sasai Y, Hashimoto N. (2002). “Optimal conditions for in vivo induction of dopaminergic neurons from ES cells through stromal cell-derived inducing activity.”. J Neurosci Res 69 (6):  934-939. http://www.ncbi.nlm.nih.gov/pubmed/12205686. Haruta M, Sasai Y, Kawasaki H, Amemiya K, Ooto S, Kitada M, Suemori H, Nakatsuji N, Ide C, Honda Y, Takahashi M. (March 2004). “In vitro and in vivo characterization of pigment epithelial cells differentiated from primate embryonic stem cells”. Invest Ophthalmol Vis Sci 45 (3):  1020-1025. http://www.ncbi.nlm.nih.gov/pubmed/14985325. Watanabe K, Ueno M, Kamiya D, Nishiyama A, Matsumura M, Wataya T, Takahashi J, Nishikawa S, Nishikawa S-I, Muguruma K, Sasai Y (2007). “A ROCK inhibitor permits survival of dissociated human embryonic stem cells”. Nat Biotech 25:  681-686. https://doi.org/10.1038/nbt1310. Fumitaka Osakada , Hanako Ikeda , Michiko Mandai , Takafumi Wataya , Kiichi Watanabe , Nagahisa Yoshimura , Akinori Akaike , Yoshiki Sasai, Masayo Takahashi (1 February 2008). “Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells”. Nat Biotechnol 26:  215-224. https://doi.org/10.1038/nbt1384. Hayashi H, Morizane A, Koyanagi M, Ono Y, Sasai Y, Hashimoto N, Takahashi J (2008). “Meningeal cells induce dopaminergic neurons from embryonic stem cells”. Eur J Neurosci 27:  261-268. http://www.ncbi.nlm.nih.gov/pubmed/18215228. Osakada F, Ikeda H, Mandai M, Wataya T, Watanabe K, Yoshimura N, Akaike A, Sasai Y, Takahashi M. (2008). “Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells”. Nature Biotechnology 26:  215-224. http://www.ncbi.nlm.nih.gov/pubmed/18246062. Fumitaka Osakada, Hanako Ikeda, Yoshiki Sasai, Masayo Takahashi (2009). “Stepwise differentiation of pluripotent stem cells into retinal cells”. Nature Protocols 4:  811-824. PMID 19444239. https://doi.org/10.1038/nprot.2009.51. Doi D, Morizane A, Kikuchi T, Onoe H, Hayashi T, Kawasaki T, Motono M, Sasai Y, Saiki H, Gomi M, Yoshikawa T, Hayashi H, Shinoyama M, Mohamed R, Suemori H, Miyamoto S, Takahashi J (2012). “Prolonged maturation culture favors a reduction in the tumorigenicity and the dopaminergic function of human ESC-derived neural cells in a primate model of Parkinson’s disease”. Stem Cells 30 (5):  935-945. https://doi.org/10.1002/stem.1060. Obokata, H.; Wakayama, T.; Sasai, Y.; Kojima, K.; Vacanti, M. P.; Niwa, H.; Yamato, M.; Vacanti, C. A. (2 July 2014). “Retraction:Stimulus-triggered fate conversion of somatic cells into pluripotency”. Nature 505:  641-647. https://doi.org/10.1038/nature13598. Obokata, H.; Sasai, Y.; Niwa, H.; Kadota, M.; Andrabi, M.; Takata, N.; Tokoro, M.; Terashita, Y.; Yonemura, S.; Vacanti, C. A.; Wakayama, T. (2 July 2014). “Retraction:Bidirectional developmental potential in reprogrammed cells with acquired pluripotency”. Nature 505:  676-680. https://doi.org/10.1038/nature13599. H. Obokata, Y. Sasai, H. Niwa (March 2014). “Essential technical tips for STAP cell conversion culture from somatic cells”. Protocol Exchange. https://doi.org/10.1038/protex.2014.008. （2014年7月2日撤回済み）Juthaporn Assawachananont, Michiko Mandaiemail, Satoshi Okamoto, Chikako Yamada, Mototsugu Eiraku, Shigenobu Yonemura, Yoshiki Sasai, Masayo Takahashi (6 May 2014). “Transplantation of Embryonic and Induced Pluripotent Stem Cell-Derived 3D Retinal Sheets into Retinal Degenerative Mice”. Stem Cell Reports 2 (5):  662-674. https://doi.org/10.1016/j.stemcr.2014.03.011.