Question: Why did Jane Pierce's husband die?

Knowledge 1: Jane Pierce
Jane Means Pierce ("née" Appleton; March 12, 1806 – December 2, 1863), wife of U.S. President Franklin Pierce, was the First Lady of the United States from 1853 to 1857. [SEP] Knowledge 2: Franklin Pierce
Franklin Pierce (November 23, 1804 – October 8, 1869) was the 14th president of the United States (1853–1857), a northern Democrat who saw the abolitionist movement as a fundamental threat to the unity of the nation.He alienated anti-slavery groups by championing and signing the Kansas–Nebraska Act and enforcing the Fugitive Slave Act, yet he failed to stem conflict between North and South, setting the stage for Southern secession and the American Civil War.Pierce was born in New Hampshire, and served in the U.S. House of Representatives and the Senate until he resigned from the Senate in 1842.His private law practice was a success, and he was appointed New Hampshire's U.S. Attorney in 1845.He took part in the Mexican–American War as a brigadier general in the Army.He was seen by Democrats as a compromise candidate uniting northern and southern interests and was nominated as the party's candidate for president on the 49th ballot at the 1852 Democratic National Convention.He and running mateWilliam R. King easily defeated the Whig Party ticket of Winfield Scott and William A. Graham in the 1852 presidential election.As president, Pierce simultaneously attempted to enforce neutral standards for civil service while also satisfying the diverse elements of the Democratic Party with patronage, an effort which largely failed and turned many in his party against him.He was a Young America expansionist who signed the Gadsden Purchase of land from Mexico and led a failed attempt to acquire Cuba from Spain.He signed trade treaties with Britain and Japan, while his Cabinet reformed their departments and improved accountability, but these successes were overshadowed by political strife during his presidency.His popularity declined sharply in the Northern states after he supported the Kansas–Nebraska Act, which nullified the Missouri Compromise, while many whites in the South continued to support him.Passage of the act led to violent conflict over the expansion of slavery in the American West.Pierce's administration was further damaged when several of his diplomats issued the Ostend Manifesto calling for the annexation of Cuba, a document which was roundly criticized.He fully expected to be renominated by the Democrats in the 1856 presidential election, but was abandoned by his party and his bid failed.His reputation in the North suffered further during the American Civil War as he became a vocal critic of President Abraham Lincoln.Pierce was popular and outgoing, but his family life was a grim affair, with his wife Jane suffering from illness and depression for much of her life.All of their children died young, their last son being gruesomely killed in a train accident while the family was traveling shortly before Pierce's inauguration.He was a heavy drinker for much of his life, and he died of cirrhosis of the liver in 1869.Historians and scholars generally rank Pierce as one of the worst and least memorable U.S. Presidents.
Knowledge 1: Franklin Pierce
Franklin Pierce (November 23, 1804 – October 8, 1869) was the 14th president of the United States (1853–1857), a northern Democrat who saw the abolitionist movement as a fundamental threat to the unity of the nation.He alienated anti-slavery groups by championing and signing the Kansas–Nebraska Act and enforcing the Fugitive Slave Act, yet he failed to stem conflict between North and South, setting the stage for Southern secession and the American Civil War.Pierce was born in New Hampshire, and served in the U.S. House of Representatives and the Senate until he resigned from the Senate in 1842.His private law practice was a success, and he was appointed New Hampshire's U.S. Attorney in 1845.He took part in the Mexican–American War as a brigadier general in the Army.He was seen by Democrats as a compromise candidate uniting northern and southern interests and was nominated as the party's candidate for president on the 49th ballot at the 1852 Democratic National Convention.He and running mateWilliam R. King easily defeated the Whig Party ticket of Winfield Scott and William A. Graham in the 1852 presidential election.As president, Pierce simultaneously attempted to enforce neutral standards for civil service while also satisfying the diverse elements of the Democratic Party with patronage, an effort which largely failed and turned many in his party against him.He was a Young America expansionist who signed the Gadsden Purchase of land from Mexico and led a failed attempt to acquire Cuba from Spain.He signed trade treaties with Britain and Japan, while his Cabinet reformed their departments and improved accountability, but these successes were overshadowed by political strife during his presidency.His popularity declined sharply in the Northern states after he supported the Kansas–Nebraska Act, which nullified the Missouri Compromise, while many whites in the South continued to support him.Passage of the act led to violent conflict over the expansion of slavery in the American West.Pierce's administration was further damaged when several of his diplomats issued the Ostend Manifesto calling for the annexation of Cuba, a document which was roundly criticized.He fully expected to be renominated by the Democrats in the 1856 presidential election, but was abandoned by his party and his bid failed.His reputation in the North suffered further during the American Civil War as he became a vocal critic of President Abraham Lincoln.Pierce was popular and outgoing, but his family life was a grim affair, with his wife Jane suffering from illness and depression for much of her life.All of their children died young, their last son being gruesomely killed in a train accident while the family was traveling shortly before Pierce's inauguration.He was a heavy drinker for much of his life, and he died of cirrhosis of the liver in 1869.Historians and scholars generally rank Pierce as one of the worst and least memorable U.S. Presidents. [SEP] Knowledge 2: Margherita Gonzaga, Duchess of Lorraine
Margherita Gonzaga (2 October 1591 – 7 February 1632) was Duchess of Lorraine from 1606 until her husband's death in 1624.
Knowledge 1: Jane Pierce
Jane Means Pierce ("née" Appleton; March 12, 1806 – December 2, 1863), wife of U.S. President Franklin Pierce, was the First Lady of the United States from 1853 to 1857. [SEP] Knowledge 2: Margherita Gonzaga, Duchess of Lorraine
Margherita Gonzaga (2 October 1591 – 7 February 1632) was Duchess of Lorraine from 1606 until her husband's death in 1624.

Answer: cirrhosis