Question: Who has the major league home run record?
Disambiguated questions and answers: question: Who has the major league home run record for a career?
Who has the major league home run record for a season?
Who has the major league home runs allowed record?
answer: Barry Bonds
Bonds
Barry Bonds
Bonds
Moyer
Jamie Moyer
Natural Questions answer: Barry Bonds (from the Wikipedia article "List of Major League Baseball career home run leaders")