Question: Who has the most passing touchdowns in the nfl?
Disambiguated questions and answers: question: Who has the most passing touchdowns in a career in the  regular season in the NFL?
Who has the most passing passing touchdowns in a career in the NFL, including playoff games?
Who has the most passing touchdowns in a single season in the NFL?
answer: Drew Brees
Tom Brady
Peyton Manning
Natural Questions answer: Peyton Manning (from the Wikipedia article "List of National Football League career passing touchdowns leaders")