Question: what can change the binding properties of a protein
[{'answer': 'charge', 'provenance': [{'wikipedia_id': '2202422', 'title': 'Ligand (biochemistry)', 'start_paragraph_id': 1, 'start_character': 552, 'end_paragraph_id': 1, 'end_character': 558, 'bleu_score': 1.0, 'section': 'Section::::Abstract.'}]}, {'answer': 'hydrophobicity', 'provenance': [{'wikipedia_id': '2202422', 'title': 'Ligand (biochemistry)', 'start_paragraph_id': 1, 'start_character': 560, 'end_paragraph_id': 1, 'end_character': 574, 'bleu_score': 1.0, 'section': 'Section::::Abstract.'}]}, {'answer': 'molecular structure', 'provenance': [{'wikipedia_id': '2202422', 'title': 'Ligand (biochemistry)', 'start_paragraph_id': 1, 'start_character': 580, 'end_paragraph_id': 1, 'end_character': 599, 'bleu_score': 1.0, 'section': 'Section::::Abstract.'}]}, {'provenance': [{'wikipedia_id': '2202422', 'title': 'Ligand (biochemistry)', 'start_paragraph_id': 1, 'start_character': 0, 'end_paragraph_id': 1, 'end_character': 730, 'bleu_score': 0.970323832779009, 'meta': {'yes_no_answer': 'NONE', 'annotation_id': 7642959849079442785}, 'section': 'Section::::Abstract.'}]}]