Question: which term describes the replacement of damaged cells to mend a tissue
[{'answer': 'Stromal cells', 'provenance': [{'wikipedia_id': '5221389', 'title': 'Cell damage', 'start_paragraph_id': 41, 'start_character': 125, 'end_paragraph_id': 41, 'end_character': 138, 'bleu_score': 1.0, 'section': 'Section::::Repair.:Replacement.\n'}]}, {'provenance': [{'wikipedia_id': '5221389', 'title': 'Cell damage', 'start_paragraph_id': 0, 'start_character': 0, 'end_paragraph_id': 0, 'end_character': 0, 'bleu_score': 1.0, 'meta': {'yes_no_answer': 'NONE', 'annotation_id': 16548509990604031922}, 'section': 'Section::::Abstract.'}]}, {'provenance': [{'wikipedia_id': '5221389', 'title': 'Cell damage', 'start_paragraph_id': 41, 'start_character': 0, 'end_paragraph_id': 41, 'end_character': 305, 'bleu_score': 0.959574895300321, 'meta': {'yes_no_answer': 'NONE', 'annotation_id': 16548509990604031922}, 'section': 'Section::::Repair.:Replacement.\n'}]}, {'provenance': [{'wikipedia_id': '19042351', 'title': 'Articular cartilage repair', 'section': 'Section::::Different articular cartilage repair procedures.:Autologous Mesenchymal Stem Cell Transplant.\n', 'start_paragraph_id': 25, 'end_paragraph_id': 25, 'meta': {'evidence_span': ["matrix structure. These transplanted cells thrive in their new environment, forming new articular cartilage. For years, the concept of harvesting stem cells and re-implanting them into one's own body to regenerate organs and tissues has been embraced and researched in animal models. In particular, mesenchymal stem cells have been shown in animal models to regenerate cartilage[1]. Recently, there has been a published case report of decrease in knee pain in a single individual using autologous mesenchymal stem cells.[2]An advantage to this approach is that a person's own stem cells are used, avoiding transmission of genetic diseases. It is also minimally invasive, minimally painful and has a very short recovery period. This alternative to the current available treatments was shown not to cause cancer in patients who were followed for 3 years after the procedure.", "matrix structure. These transplanted cells thrive in their new environment, forming new articular cartilage. For years, the concept of harvesting stem cells and re-implanting them into one's own body to regenerate organs and tissues has been embraced and researched in animal models. In particular, mesenchymal stem cells have been shown in animal models to regenerate cartilage[1]. Recently, there has been a published case report of decrease in knee pain in a single individual using autologous mesenchymal stem cells.[2]An advantage to this approach is that a person's own stem cells are used, avoiding transmission of genetic diseases. It is also minimally invasive, minimally painful and has a very short recovery period. This alternative to the current available treatments was shown not to cause cancer in patients who were followed for 3 years after the procedure.\rhighlight sentence(s) containing evidence, not only the answer"]}}]}, {'provenance': [{'wikipedia_id': '33993737', 'title': 'Decellularization', 'section': 'Section::::Abstract.', 'start_paragraph_id': 1, 'end_paragraph_id': 1, 'meta': {'evidence_span': ['Decellularization (also spelt decellularisation in British English) is the process used in biomedical engineering to isolate the extracellular matrix (ECM) of a tissue from its inhabiting cells, leaving an ECM scaffold of the original tissue, which can be used in artificial organ and tissue regeneration. Organ and tissue transplantation treat a variety of medical problems, ranging from end organ failure to cosmetic surgery. One of the greatest limitations to organ transplantation derives from organ rejection caused by antibodies of the transplant recipient reacting to donor antigens on cell surfaces within the donor organ. Because of unfavorable immune responses, transplant patients suffer a lifetime taking immunosuppressing medication. Stephen F. Badylak pioneered the process of decellularization at the McGowan Institute for Regenerative Medicine at the University of Pittsburgh. This process creates a natural biomaterial to act as a scaffold for cell growth, differentiation and tissue development. By recellularizing an ECM scaffold with a patients own cells, the adverse immune response is eliminated. Nowadays, commercially available ECM scaffolds are available for a wide variety of tissue engineering. Using peracetic acid to decellularize ECM scaffolds have been found to be false and only disinfects the tissue.', 'Decellularization (also spelt decellularisation in British English) is the process used in biomedical engineering to isolate the extracellular matrix (ECM) of a tissue from its inhabiting cells, leaving an ECM scaffold of the original tissue, which can be used in artificial organ and tissue regeneration. Organ and tissue transplantation treat a variety of medical problems, ranging from end organ failure to cosmetic surgery. One of the greatest limitations to organ transplantation derives from organ rejection caused by antibodies of the transplant recipient reacting to donor antigens on cell surfaces within the donor organ. Because of unfavorable immune responses, transplant patients suffer a lifetime taking immunosuppressing medication. Stephen F. Badylak pioneered the process of decellularization at the McGowan Institute for Regenerative Medicine at the University of Pittsburgh. This process creates a natural biomaterial to act as a scaffold for cell growth, differentiation and tissue development. By recellularizing an ECM scaffold with a patients own cells, the adverse immune response is eliminated. Nowadays, commercially available ECM scaffolds are available for a wide variety of tissue engineering. Using peracetic acid to decellularize ECM scaffolds have been found to be false and only disinfects the tissue.']}}]}, {'provenance': [{'wikipedia_id': '19074150', 'title': 'Autologous chondrocyte implantation', 'section': 'Section::::Procedure.\n', 'start_paragraph_id': 5, 'end_paragraph_id': 5, 'meta': {'evidence_span': ['This cell based articular cartilage repair procedure takes place in three stages. In a first stage, between 200 and 300 milligrams cartilage is sampled arthroscopically from a less weight bearing area from either the intercondylar notch or the superior ridge of the medial or lateral femoral condyle of the patient. The matrix is removed enzymatically and the chondrocytes isolated. These cells are grown in vitro in a specialised laboratory for approximately four to six weeks, until there are enough cells to reimplant on the damaged area of the articular cartilage. The patient then undergoes a second treatment, in which the chondrocytes are applied on the damaged area during an open-knee surgery (also called arthrotomy). These autologous cells should adapt themselves to their new environment by forming new cartilage. During the implantation, chondrocytes are applied on the damaged area in combination with a membrane (tibial periosteum or biomembrane) or pre-seeded in a scaffold matrix.', 'This cell based articular cartilage repair procedure takes place in three stages. In a first stage, between 200 and 300 milligrams cartilage is sampled arthroscopically from a less weight bearing area from either the intercondylar notch or the superior ridge of the medial or lateral femoral condyle of the patient. The matrix is removed enzymatically and the chondrocytes isolated. These cells are grown in vitro in a specialised laboratory for approximately four to six weeks, until there are enough cells to reimplant on the damaged area of the articular cartilage. The patient then undergoes a second treatment, in which the chondrocytes are applied on the damaged area during an open-knee surgery (also called arthrotomy). These autologous cells should adapt themselves to their new environment by forming new cartilage. During the implantation, chondrocytes are applied on the damaged area in combination with a membrane (tibial periosteum or biomembrane) or pre-seeded in a scaffold matrix.\rhighlight sentence(s) containing evidence, not only the answer']}}]}, {'provenance': [{'wikipedia_id': '5221389', 'title': 'Cell damage', 'section': 'Section::::Repair.:Replacement.\n', 'start_paragraph_id': 41, 'end_paragraph_id': 41, 'meta': {'evidence_span': ['When a cell cannot be regenerated the body will replace it with stromal connective tissue to maintain tissue/organ function. Stromal cells are the cells that support the parenchymal cells in any organ. Fibroblasts, immune cells, pericytes, and inflammatory cells are the most common types of stromal cells.', 'Stromal cells are the cells that support the parenchymal cells in any organ. Fibroblasts, immune cells, pericytes, and inflammatory cells are the most common types of stromal cells']}}]}]