Question: when was smoking first known to be harmful
[{'answer': 'Early 17th century', 'provenance': [{'wikipedia_id': '21797606', 'title': 'History of smoking', 'start_paragraph_id': 50, 'start_character': 0, 'end_paragraph_id': 50, 'end_character': 18, 'bleu_score': 1.0, 'section': 'Section::::Social stigma.:Early opposition.\n'}]}, {'provenance': [{'wikipedia_id': '21797606', 'title': 'History of smoking', 'start_paragraph_id': 50, 'start_character': 0, 'end_paragraph_id': 50, 'end_character': 453, 'bleu_score': 0.970362113628587, 'meta': {'yes_no_answer': 'NONE', 'annotation_id': 6308735889054078761}, 'section': 'Section::::Social stigma.:Early opposition.\n'}]}]