Kt/V, like the URR, focuses on urea as the target solute, and is based on the assumption that removal of urea is from a single space – urea distribution volume, or V {\displaystyle V\,} similar in capacity to the total body water.
Kt/V、如URR一樣，著重於尿素作為目標溶質，且基於這樣的假設、除去尿素是由單一的空間 - 尿素分佈的容積，或 V {\displaystyle V\,} 類似於總身體水的容量。