In 2005, Dio was revealed to be the voice behind Dr. X in Operation: Mindcrime II, the sequel to Queensrÿche's seminal concept album Operation: Mindcrime.
Në vitin 2005, u zbulua se Dio ishte zëri pas Dr. X në Operation: Mindcrime II, vazhdimi i albumit konceptual bazë të Queensrÿche, Operation: Mindcrime.