The Astros (known as the "Colt .45s" during their first three seasons) became the first southern major league franchise since the Louisville Colonels folded in 1899 and the first franchise to be located along the Gulf Coast.
Astros (známi ako "Colt .45s" počas prvých troch sezón) sa stali prvou južanskou organizáciou v major league od čias mužstva Louisville Colonels, ktoré skončilo v roku 1899.