In a 2006 study, 45 patients had colonic tumors with hypermethylated WRN gene promoters (silenced WRN expression), and 43 patients had tumors with unmethylated WRN gene promoters, so that WRN protein expression was high.
V štúdii z roku 2006 malo 45 pacientov nádory hrubého čreva s hypermetylovanými promotérmi WRN (umlčaná expresia WRN) a 43 pacientov malo nádory s nemetylovanými promotérmi WRN génov, takže proteínová expresia WRN génov bola vysoká.