His reign lasted up to his death on 31 March 1462, and he was succeeded by Joasaph I. Some scholars suggest Gennadius Scholarius (second term) and Sophronius I as Isidore's successor in place of Joasaph I: see the Article List of Patriarchs of Constantinople.
Неговото владеење траело до неговата смрт на 31 март 1462, за подоцна да биде наследен од патријархот Јоасаф I. Some scholars suggest Gennadius Scholarius (second term) and Sophronius I as Isidore's successor in place of Joasaph I: see the Article List of Patriarchs of Constantinople.