He is best known as the creator of the animated sitcom Family Guy (1999–2003, 2005–present) and as co-creator of American Dad! (2005–present) and The Cleveland Show (2009–2013), for which he also voices many of the shows' various characters.
Dia adalah pencipta acara Family Guy (1999-2002, 2005-sekarang) dan co-pencipta American Dad! (2005-sekarang) dan The Cleveland show (2009-sekarang), di mana dia juga menyuarakan banyak berbagai karakter menunjukkan.