His reign was a turbulent one, and in 1185 Andronikos was dethroned and killed while his son Manuel was blinded and may have died from this mutilation.
Pemerintahannya bergejolak, dan pada tahun 1185 Andronikos digulingkan dan dibunuh sementara putranya Manouel dibutakan dan mungkin tewas akibat mutilasi ini.