In February 2015 it was reported that Doctors of the World had submitted an objection to Gilead's patent at the European Patent Office claiming that the structure of sofosbuvir is based on already known molecules.
Pada bulan Februari 2015 dilaporkan Dokter Dunia telah mengajukan keberatan terhadap paten Gilead kepada Kantor Paten Eropa mengklaim bahwa struktur sofosbuvir berdasar pada molekul yang sudah dikenal.