The film tells the story of the Joads, an Oklahoma family, who, after losing their farm during the Great Depression in the 1930s, become migrant workers and end up in California.
Film tersebut mengisahkan tentnag cerita keluarga Joad asal Oklahoma yang kehilangan kebun mereka pada masa Depresi Besar pada 1930an, menjadi buruh migran dan berakhir di California.