Issoufou was the Prime Minister of Niger from 1993 to 1994, President of the National Assembly from 1995 to 1996, and he has been a candidate in each presidential election since 1993.
Issoufou adalah Perdana Menteri Niger 1993-1994, Presiden Majelis Nasional 1995-1996, dan ia telah menjadi kandidat di setiap pemilihan presiden sejak tahun 1993.