She met George Herbert Walker Bush at the age of sixteen, and the two married in Rye, New York in 1945, while he was on leave during his deployment as a Naval officer in World War II.
Ia bertemu George Herbert Walker Bush pada usia 16 tahun, dan keduanya menikah di Rye, New York, pada tahun 1945, ketika ia pulang setelah lepas jabatan sebagai staf Angkatan Laut saat Perang Dunia II.