At Yale, Collins worked under the direction of Sherman Weissman, and in 1984 the two published a paper, "Directional Cloning of DNA Fragments at a Large distance From an Initial Probe: a Circularization Method".
Di Yale, Collins bekerja di bawah direksi Sherman Weissman, dan pada tahun 1984 kedua sarjana tersebut menerbitkan sebuah makalah, "Directional Cloning of DNA Fragments at a Large distance From an Initial Probe: a Circularization Method".