According to Hyginus, Agnodice studied medicine under Herophilus, and worked as a physician in her home city of Athens disguised as a man, because women at the time were forbidden from practising medicine.
Menurut Hyginus, Agnodike belajar kedokteran di bawah Herophilos, dan bekerja sebagai dokter di kota kelahirannya di Athena yang menyamar sebagai seorang pria, karena wanita pada saat itu dilarang mempraktikkan pengobatan.