She gave birth to Darius, Oxyathres, and possibly also Stateira I. At the Battle of Issus (333 BC), Darius' army was routed and the Persian king fled the field, leaving his extended family, including his mother, his wife Stateira I, his children, and many others to the mercy of Alexander.
Ia melahirkan Darius, Oxyathres, dan mungkin juga Stateira I. Pada Pertempuran Issos (333 SM), tentara Darius diarahkan dan raja Persia melarikan diri dari lapangan, meninggalkan keluarga besarnya, termasuk ibundanya, istrinya Stateira I, anak-anaknya, dan banyak lagi untuk pengampunan Aleksander.