The World Health Organization recommends a pentavalent vaccine, combining vaccines against diphtheria, tetanus, pertussis and Haemophilus influenzae type B with the vaccine against hepatitis B. There is not yet sufficient evidence on how effective this pentavalent vaccine is in relation to the individual vaccines.
Organisasi Kesehatan Dunia merekomendasikan vaksin pentavalen, menggabungkan vaksin difteri, tetanus, pertusis, dan Haemophilus influenzae tipe B dengan vaksin hepatitis B. Belum ada bukti yang memadai mengenai seberapa efektif vaksin pentavalen ini jika dibandingkan dengan vaksin individual.