Around 1592, the Spanish galleon San Clemente brought 50 kilograms (110 lb) of tobacco seed to the Philippines over the Acapulco-Manila trade route.
Sekitar tahun 1592, di Spanyol Galleon San Clemente membawa 50 kilogram (110 lb) benih tembakau ke Filipina melalui Acapulco-rute perdagangan Manila.