The curial office of the Cardinal Nephew as well as the institution of the cardinal-nephew declined as the power of the Cardinal Secretary of State increased and the temporal power of popes decreased in the 17th and 18th centuries.
Jabatan kuria Kardinal Keponakan serta lembaga kardinal keponakan dibubarkan ketika kekuasaan Kardinal Sekretaris Negara meningkat dan kekuasaan temporal para paus dicabut pada abad ke-17 dan ke-18.