Because CFCs contribute to ozone depletion in the upper atmosphere, the manufacture of such compounds has been phased out under the Montreal Protocol, and they are being replaced with other products such as hydrofluorocarbons (HFCs) (e.g., R-410A) and R-134a.
Karena CFC berkontribusi terhadap penipisan ozon di atmosfer atas, pembuatan senyawa tersebut telah dihapuskan di bawah Protokol Montreal, dan diganti dengan produk lain seperti hidrofluorokarbon (HFC) (misalnya, R-410A) dan R-134a.