Ederson first played some matches in the Segunda Liga with the reserve team and in the Taça da Liga with the main squad, before playing in the Primeira Liga on 5 March 2016 against local rivals Sporting CP, replacing injured Júlio César.
Ederson pertama kali memainkan beberapa pertandingan di Segunda Liga dengan tim cadangan dan di Taça da Liga dengan skuat utama, sebelum bermain di Liga Primeira pada 5 Maret 2016 melawan rival lokal Sporting CP, menggantikan Júlio César yang cedera.