Trieste Science+Fiction Festival was founded in 2000 under the name of Science plus Fiction by the Research and Experimentation Centre La Cappella Underground with the ambitious purpose of re-launching the Festival Internazionale del film di fantascienza (International Science Fiction Film Festival), which had been held in the northern Italian city of Trieste in the years 1963–1982.
Festival Trieste Science+Fiction didirikan pada tahun 2000 dengan nama Science plus Fiction oleh Research and Experimentation Centre La Cappella Underground dengan tujuan meluncurkan ulang Festival Internazionale del film di fantascienza (Festival Film Fiksi Ilmiah Internasional), yang diadakan di kota Trieste, utara Italia pada tahun 1963–1982.