As many of the downstream transducer and effector molecules of GPCRs (including those involved in negative feedback pathways) are also targeted to lipid rafts, this has the effect of facilitating rapid receptor signaling.
Karena banyak molekul transduser hilir dan efektor GPCR (termasuk yang terlibat dalam jalur umpan balik negatif) juga ditargetkan untuk rakit lipid, hal ini memiliki efek memfasilitasi pensinyalan reseptor cepat.