With his wife Isabella I the Catholic (whom he married 19 October 1469), King Ferdinand had seven children: Isabella (1470–1498), Princess of Asturias (1497–1498).
Dengan istrinya Isabel I (yang ia nikahi pada tanggal 19 Oktober 1469), Raja Ferrando memiliki tujuh orang anak : Isabel (1470–1498), Putri Asturias (1497–1498).