Higuaín was at the centre of much transfer speculation, with many newspapers linking him to a move to Arsenal before Napoli's president Aurelio De Laurentiis said that Higuaín, along with Liverpool goalkeeper Pepe Reina, had passed their medicals and that the Argentine had signed a five-year deal with the Italian club, with Higuaín joining for €40 million.
Higuain berada di banyak spekulasi transfer, dengan banyak surat kabar yang mengaitkannya dengan bergabung dengan Arsenal sebelum presiden Napoli Aurelio De Laurentiis mengatakan bahwa Higuain bersama dengan kiper Liverpool Pepe Reina telah melewati tes medis mereka dan bahwa pemain Argentina tersebut telah menandatangani kontrak lima tahun dengan klub Italia senilai € 40 juta.