In August 2015, at Disney's D23 Expo, it was announced that Hayden Rolence would voice Nemo, replacing Alexander Gould from the first film, whose voice has deepened since reaching adulthood (Gould voiced a minor character in the sequel instead).
Pada bulan Agustus 2015, di Disney D23 Expo, diumumkan bahwa Hayden Rolence akan menyuarakan Nemo, menggantikan Alexander Gould dari film pertama, yang suaranya telah memperdalam sejak mencapai usia dewasa (Gould menyuarakan karakter minor dalam sekuel sebaliknya).