Karina's Zelfopoffering was directed by Ph. Carli, who had been trained as a documentary filmmaker and had made his feature film debut two years earlier with De Stem des Bloeds.
Karina's Zelfopoffering disutradarai Ph. Carli, seorang pembuat film dokumenter terlatih dan telah memproduseri film perdananya, De Stem des Bloeds, dua tahun sebelumnya.