He later began focusing increasingly on his music career, returning to acting with Panic Room (2002), Alexander (2004), Lord of War (2005), Lonely Hearts (2006), Chapter 27 (2007), and Mr. Nobody (2009).
Leto kemudian mulai berfokus pada karier musiknya, dan kembali berkecimpung di dunia akting dengan membintangi Panic Room (2002), Alexander (2004), Lord of War (2005), Lonely Hearts (2006), Chapter 27 (2007), dan Mr. Nobody (2009).