Elisabeth of Parma had also wanted the Grand Duchy of Tuscany for her son Charles III of Spain; Gian Gastone de' Medici was childless and was related to Elisabeth via her great-grandmother Margherita de' Medici.
Elisabeth Farnese juga menginginkan kadipaten Toskana untuk putranya Charles III dari Spanyol; Gian Gastone de' Medici tidak memiliki keturunan dan memiliki hubungan dengan Elisabeth melalui nenek buyutnya Margherita de' Medici.