A 1980 letter in Trends in Biochemistry Sciences noted the confusion in the literature and the essentially arbitrary distinction made between prosthetic groups and coenzymes group and proposed the following scheme.
Suatu surat tahun 1980 dalam Trends in Biochemistry Sciences mencatat kebingungan dalam literatur dan perbedaan yang sewenang-wenang sewenang-wenang antara kelompok prostetik dan kelompok koenzim dan mengusulkan skema berikut.