As well as being a prominent member of the Cuban Council of Ministers, Pérez Roque was also a member of the Central Committee of the Communist Party of Cuba and served on the Council of State.
Selain menjadi anggota terkemuka dari Dewan Menteri Kuba, Pérez Roque juga merupakan anggota dari Komite Sentral dari Partai Komunis Kuba dan berdinas di Dewan Negara.