In his book, Evolution: A View from the 21st Century, Shapiro refers to this concept of "natural genetic engineering", which he says, has proved troublesome, because many scientists feel that it supports the intelligent design argument.
Dalam bukunya Evolution: A View from the 21st Century (Evolusi: Pandangan dari Abad XXI), Shapiro mengacu pada konsep "rekayasa genetik alami", yang katanya, telah terbukti merepotkan karena banyak ilmuwan merasa konsep itu mendukung argumen perancangan cerdas.