On October 5, 2015, after her three daughters set aside their initial objections, Robredo announced that she would run for the post of Vice President of the Philippines under the Liberal Party in the 2016 election, as the running mate of presidential candidate Mar Roxas.
Pada 5 Oktober 2015, setelah ketiga putrinya mengundurkan keberatan mereka, Robredo mengumumkan bahwa ia akan ikut berkompetisi untuk kedudukan Wakil Presiden Filipina dengan naungan Liberal Party pada pemilihan 2016, sebagai rekan Kandidat Presiden Mar Roxas.