Although his laboratories were often plagued by lack of financial support and second-rate equipment, his research into sugar nucleotides, carbohydrate metabolism, and renal hypertension has garnered international attention and fame and has led to significant progress in understanding, diagnosing and treating the congenital disease galactosemia.
Meski laboratoriumnya sering terganggu oleh kurangnya bantuan uang dan peralatan tingkat dua, penelitiannya tentang nukleotida gula, metabolisme karbohidrat dan hipertensi ginjal mendapatkan perhatian dan kepopuleran internasional internationaal dan telah menimbulkan langkah maju dalam pemahaman, diagnosis dan penanganan penyakit bawaan galaktosemia.