On the other hand, Jonathan Lunine has argued that any living things in Titan's cryogenic hydrocarbon lakes would need to be so different chemically from Earth life that it would not be possible for one to be the ancestor of the other.
Di sisi lain, Jonathan Lunine menyatakan bahwa kehidupan di danau hidrokarbon kriogenik Titan seharusnya secara kimiawi sangat berbeda dengan kehidupan Bumi sehingga keduanya tidak mungkin terkait.