Unlike some routes, which are disconnected into segments because of encroaching Interstate Highways, the two portions of US 2 were designed to be separate in the original 1926 highway plan.
Tidak seperti rute lainnya yang putus menjadi beberapa bagian karena keberadaan Interstate Highway, dua bagian US  2 dirancang terpisah pada tata jalan bebas hambatan asli tahun 1926.