Almost all of the methylations from the parents are erased, first during gametogenesis, and again in early embryogenesis, with demethylation and remethylation occurring each time.
Hampir semua metilasi dari orang tua dihapus, pertama selama gametogenesis, dan kedua pada embriogenesis awal, dengan demetilasi dan remetilasi terjadi setiap waktu.