Saint Charles Borromeo, cardinal-nephew of Pope Pius IV (1559–1565), had ensured the subordination of the secretarius intimus to the Cardinal Nephew, which came to be sometimes known as the secretarius maior.
Santo Charles Borromeo, kardinal keponakan Paus Pius IV (1559–1565), menjajal subordinasi secretarius intimus kepada Kardinal Keponakan, yang terkadang dikenal sebagai secretarius maior.