The French Wars of Religion saw the rise of a junior branch of the Lorraine family, the House of Guise, which became a dominant force in French politics and, during the later years of Henri III's reign, was on the verge of succeeding to the throne of France.
Perang Agama Prancis menampakan kebangkitan dari cabang junior keluarga Lorraine, Rumah Guise, yang menjadi kekuatan dominan dalam politik Prancis dan, dalam tahun-tahun terakhir pemerintahan Henri III, berada di ambang keberhasilan meraih tahta Prancis.