Marking the film debut for deaf actress Matlin, Children of a Lesser God is notable for being the first since the 1926 silent film You'd Be Surprised to feature a deaf actor in a major role.
Menandai debut film untuk aktris tuli Matlin, Children of a Lesser God dikenal karena menjadi film pertama sejak film bisu 1926 You'd Be Surprised yang menampilkan aktor tuli dalam peran utama.