Inspired by several sources, including Star Trek and The Twilight Zone, the series tells the story of Mercer, Grayson, and the crew of the Orville as they embark on various diplomatic and exploratory missions.
Terinspirasi oleh beberapa sumber, termasuk Star Trek dan The Twilight Zone, seri ini menceritakan kisah Mercer, Grayson, dan kru Orville ketika mereka memulai berbagai misi diplomatik dan eksplorasi.