Much of the high technology industry base in the Champaign–Urbana metropolitan area consists of research and small start-up companies working with the University of Illinois at Urbana–Champaign.
Kebanyakan pusat industri teknologi tinggi di Wilayah Metropolitan Champaign-Urbana terdiri dari perusahaan riset dan perusahaan rintisan kecil yang bekerja sama dengan University of Illinois at Urbana-Champaign.