When molecules on each side of the equilibrium are able to further react irreversibly in secondary reactions, the final product ratio is determined according to the Curtin–Hammett principle.
Ketika molekul di setiap sisi kesetimbangan dapat bereaksi lebih lanjut secara ireversibel dalam reaksi sekunder, rasio produk akhir ditentukan sesuai dengan prinsip Curtin–Hammett.