Unlike the first generation NSX which was manufactured in Japan, the new NSX was designed and engineered in Marysville, Ohio, at Honda's plant, led by chief engineer Ted Klaus.
Berbeda dengan NSX generasi pertama yang diproduksi di Jepang, NSX baru dirancang dan direkayasa di Marysville, Ohio, di pabrik Honda, dipimpin oleh chief engineer Ted Klaus.