Originally coming to prominence through her comedy partnership with Mel Giedroyc in Mel and Sue, she has since become best known as a radio broadcaster and television presenter, notably of The Great British Bake Off (2010–2016) and Insert Name Here (2016–present).
Awalnya menonjol melalui kemitraan komedi dengan Mel Giedroyc dalam Mel and Sue, dia sejak itu telah menjadi dikenal sebagai penyiar radio dan presenter televisi, terutama Great British Bake Off (2010-2016) dan Insert Name Here (2016–sekarang).