An N-terminal Z-disc region and a C-terminal M-line region bind to the Z-line and M-line of the sarcomere, respectively, so that a single titin molecule spans half the length of a sarcomere.
Daerah cakram Z N-terminal dan daerah garis M C-terminal masing-masing terikat ke garis Z dan garis M sarkomer, sehingga satu molekul titin membentang setengah panjang sarkomer.