Oss is also host to the professional football team FC Oss, and is the birthplace of former Manchester United and Real Madrid star Ruud van Nistelrooy, although he did not play for the local side, but for rivals FC Den Bosch.
Oss juga tuan rumah tim profesional sepak bola FC Oss, dan merupakan tempat kelahiran mantan bintang Manchester United dan Real Madrid, Ruud van Nistelrooy, meskipun ia tidak bermain di sisi lokal, tetapi bermain untuk FC Den Bosch.