Holsti worked at Stanford University as an instructor in the Department of Political Science (1962–1965), the research coordinator and associate director of Studies in International Conflict and Integration (1962–1967) and assistant professor in the Department of Political Science, (1965–1967).
Holsti pernah bekerja di Universitas Stanford sebagai instruktur Departemen Ilmu Politik (1962–1965), koordinator peneliti dan direktur asosiasi Studi Konflik Internasional dan Integrasi (1962–1967), dan dosen pembantu Departemen Ilmu Politik (1965–1967).