It has served as the home of the United Nations Office at Geneva since 1946 when the Secretary-General of the United Nations signed a Headquarters Agreement with the Swiss authorities, although Switzerland did not become a member of the United Nations until 2002.
Gedung ini menjadi kantor Perserikatan Bangsa-Bangsa di Jenewa semenjak tahun 1946 setelah Sekretaris Jenderal PBB menandatangani perjanjian dengan pemerintah Swiss, walaupun Swiss baru bergabung dengan PBB pada tahun 2002.