Rooney tried her hand at presenting when in May 2006 she assisted Sir Trevor McDonald on his show Tonight with Trevor McDonald in a programme about the genetic disorder Rett syndrome, from which her younger sister suffered.
Rooney mencoba tangannya saat menyajikan acara televisi, pada Mei 2006, dia membantu Sir Trevor McDonald pada acaranya Tonight with Trevor McDonald dalam sebuah program tentang kelainan genetik Rett syndrome, dimana adik perempuannya menderita.