Naples offered the first resistance of the whole campaign, withstanding a siege with the help of Margaritus of Brindisi's fleet, until much of the army had succumbed to malaria and disease.
Nápoles foi a primeira en ofrecer resistencia á campaña, soportando o asedio coa axuda da frota de Margaritone de Brindisi, até que gran parte do exército sucumbiu á malaria.