Based on actual events from 1956 in which five male missionaries were speared by a group of the Waodani tribe, the movie tells the story from the perspective of Steve Saint (the son of Nate Saint, one of the missionaries killed in the encounter), and Mincayani, one of the tribesmen who took part in the attack.
Baseado en feitos reais ocorridos en 1956, os cinco misioneiros foron asasinados pola tribo, e o filme conta a historia dende a perspectiva de Steve Saint (o fillo de Nate Saint, un dos misioneiros asasinados no encontro), e Mincayani, un dos homes huaorani que participou no ataque.