The Mission San Francisco de Potano, the first doctrina (a mission with a resident priest) in Florida west of the St. Johns River, was founded in 1606 at the south edge of present-day San Felasco Hammock Preserve State Park.
A Misión de San Francisco de Potano, a primeira doutrina (unha misión cun sacerdote residente) en Florida ao oeste do río Saint Johns, foi fundada en 1606 ao sur do actual Parque Estatal e Reserva de San Felasco Hammock.