Another significant military engagement on the Missouri River during this period was the 1861 Battle of Boonville, which did not affect Native Americans but rather was a turning point in the American Civil War that allowed the Union to seize control of transport on the river, discouraging the state of Missouri from joining the Confederacy.
Outro conflito militar significativo no río Missouri durante este período foi a batalla de Boonville de 1861, que non afectou os nativos americanos, senón que máis ben foi un punto de inflexión na guerra civil americana que permitiu á Union tomar o control do transporte no río, desalentando ao estado de Missouri de unirse á Confederación.