Since administering anti-TNF-α and anti-IFN-γ monoclonal antibodies neutralizes YPM toxicity in vivo, these cytokines are largely responsible for the damage caused indirectly by the exotoxin.
Como a administración de anticorpos monoclonais anti-TNF-α e anti-IFN-γ neutraliza a toxicidade de YPM in vivo, estas citocinas son en gran medida responsables dos danos causados indirectamente pola exotoxina.