Evidence for the important role antithrombin plays in regulating normal blood coagulation is demonstrated by the correlation between inherited or acquired antithrombin deficiencies and an increased risk of any affected individual developing thrombotic disease.
As probas do importante papel que desempeña a antitrombina na regulación da coagulación sanguínea normal proceden da correlación entre as deficiencias de antitrombina herdadas ou adquiridas e o incremento do risco de que calquera individuo afectado desenvolva unha doenza trombótica.