Conversely, MSH2 does not have a nuclear localization sequence (NLS), so it is believed that MSH2 and MSH6 dimerize in the cytoplasm and then are imported into the nucleus together.
Inversamente, o MSH2 non ten unha secuencia de localización nuclear (NLS), polo que se cre que a MSH2 e a MSH6 se dimerizan no citoplasma e despois son importadas xuntas ao núcleo celular.