On 7 October 2017, it was announced that Palmer would leave Renault after the end of the Japanese Grand Prix, to be replaced by Toro Rosso driver Carlos Sainz Jr., taking his seat from the United States Grand Prix onwards.
O 7 de outubro de 2017, anunciouse que Palmer abandonaría Renault despois do final do Gran Premio de Xapón, para ser substituído polo piloto de Toro Rosso Carlos Sainz, tomando o seu asento do Gran Premio dos Estados Unidos en diante.