Proteins that are essential for sister chromatid cohesion, such as Smc3 and Scc1, do not regulate the formation of covalent bonds between cohesin and DNA, indicating that DNA interaction is not sufficient for cohesion.
As proteínas que son esenciais para a cohesión das cromátides irmás, como Smc3 e Scc1, non regulan a formación de enlaces covalentes entre a cohesina e o ADN, o que indica que a interacción co ADN non é suficiente para a cohesión.