In addition to a C-terminal chymotrypsin-like serine protease domain, plasminogen contains an N-terminal Pan Apple domain (PAp) together with five Kringle domains (KR1-5).
Ademais do dominio C-terminal serina protease similar ao da quimotripsina (SP), o plasminóxeno contén un dominio N-terminal Pan Apple (PAp) xunto con cinco dominios kringle (KR1-5).