A human study of IL-7 in patients with cancer demonstrated that administration of this cytokine can transiently disrupt the homeostasis of both CD8+ and CD4+ T cells with a commensurate decrease in the percentage of CD4+CD25+Foxp3+ T regulatory cells.
Un estudo humano de IL-7 en pacientes con cancro demostra que a administración desta citocina pode alterar transitoriamente a homeostase das células T CD8+ e CD4+ cun decrecemento proporcional na porcentaxe de células T CD4+CD25+Foxp3+ reguladoras.