The term "cytosol" was first introduced in 1965 by H. A. Lardy, and initially referred to the liquid that was produced by breaking cells apart and pelleting all the insoluble components by ultracentrifugation.
O termo citosol foi introducido por primeira vez en 1965 por H.A. Lardy, e inicialmente facía referencia ao líquido que se orixinaba ao romper as células e separar todos os compoñentes insolubles por ultracentrifugación.