In order to achieve the high level of control required to co-ordinate nuclear processes such as DNA replication, repair, and transcription, cells have developed a variety of means to locally and specifically modulate chromatin structure and function.
Para conseguir o alto grao de control requirido para coordinar procesos nucleares tales como a replicación do ADN, a súa reparación e a transcrición, as células desenvolveron varios xeitos de modular a estrutura e función da cromatina de forma local e específica.