A defect in the gene for nephrin, NPHS1, is associated with congenital nephrotic syndrome of the Finnish type and causes massive amounts of protein to be leaked into the urine, or proteinuria.
Un defecto no xene da nefrina, NPHS1, está asociado coa síndrome nefrótica conxénita de tipo finlandés e causa a perda pola urina de cantidades masivas de proteínas, ou proteinuria.