This hypothesis was disproved in the 1920s by ultracentrifugation measurements by Theodor Svedberg that showed that proteins had a well-defined, reproducible molecular weight and by electrophoretic measurements by Arne Tiselius that indicated that proteins were single molecules.
Esta hipótese foi desbotada na década de 1920 polas medidas de ultracentrifugación feitas por Theodor Svedberg, que mostraban que as proteínas tiñan un peso molecular ben definido e reproducible, e polas medicións electroforéticas de Arne Tiselius, que indicaban que as proteínas eran unha soa molécula.