Proteins which use this pathway have the capability to form a beta-barrel with their C-terminus which inserts into the outer membrane, allowing the rest of the peptide (the passenger domain) to reach the outside of the cell.
As proteínas que usan esta vía teñen a capacidade de formar un barril beta cos seus extremos C-terminal inseridos na membrana externa, o que permite que o resto do péptido (o dominio pasaxeiro) atinga o exterior da célula.