N-Ethylmaleimide was used by Arthur Kornberg and colleagues to knock out DNA polymerase III in order to compare its activity to that of DNA polymerase I (pol III and I, respectively).
Arthur Kornberg e colegas utilizaron a NEM para inutilizar a ADN polimerase III para comparar a súa actividade coa da ADN polimerase I (pol III e I, respectivanmente).