Similarly, some commercially available restriction enzymes are sensitive to methylation at their cognate restriction sites, and must as mentioned previously be used on DNA passed through a dam-/dcm- strain to allow cutting.
De xeito similar, algúns encimas de restrición comerciais son sensibles á metilación nos seus sitios de restrición cognados, e deben, como se mencionou antes, utilizarse sobre ADN pasado por cepas dam-/dcm- para permitir o corte.