However, in the absence of NGF, the expression of pro-apoptotic proteins is increased when the activation of cell death-promoting transcription factors such as c-Jun are not suppressed by the aforementioned NGF-mediated cell survival pathways.
Porén, en ausencia de NGF, a expresión de proteínas proapoptóticas increméntase cando a activación de factores de transcrición que promoven a morte, como c-Jun non son suprimidos polas antes mencionadas vías de supervivencia celular mediadas por NGF.