Studies from patients suffering from endometrial cancer have shown that these patients have increased syndecan 1 expression, and also that expression of this protein positively regulates the endometrial hyperplasia that can progress to endometrial cancer .
Estudos feitos en pacientes con cancro de endometrio mostraron que ditos pacientes incrementaran a expresión de sindecano-1 e tamén que a expresión desta proteína regula positivamente a hiperplasia endometrial que pode progresar a un cancro endometrial.