The other two isoforms of SOD have not been linked to any human diseases, however, in mice inactivation of SOD2 causes perinatal lethality and inactivation of SOD1 causes hepatocellular carcinoma.
As outras dúas isoformas da SOD non foron asociadas con ningunha enfermidade humana, pero nos ratos a inactivación de SOD2 causa letalidade perinatal e a inactivación de SOD1 causa carcinoma hepatocelular.