The significance and economic impact of coronaviruses as causative agents of the common cold are hard to assess because, unlike rhinoviruses (another common cold virus), human coronaviruses are difficult to grow in the laboratory.
A importancia e impacto económico dos coronaviruses como axentes causantes de arrefriados comúns é difícil de avaliar, porque, a diferenza dos rinovirus (outro virus común dos arrefriados), os coronavirus humanos son difíciles de cultivar en laboratorio.