The linkage with risk for urothelial bladder cancer susceptibility was shown for XRCC4, but not for XRCC3 With regard to breast cancer, the linkage with "increased risk of breast cancer" was based on an examination of functional polymorphisms of the XRCC4 gene carried out in connection with a meta-analysis of five case-control studies .
Atopouse unha ligazón co risco de cancro de vexiga urotelial para XRCC4, pero non para XRCC3 En canto ao cancro de mama, a ligazón cun "incremento do risco de cancro de mama" estaba baseada nun exame de polimorfismos funcionais do xene XRCC4 levada a cabo en conexión cunha metaanálise de cinco estudos de casos control.