Mitochondrially bound hexokinase has been demonstrated to be the driving force for the extremely high glycolytic rates that take place aerobically in tumor cells (the so-called Warburg effect described by Otto Heinrich Warburg in 1930).
A hexoquinase unida ás mitocondrias é a forza impulsora das taxas glicolíticas extremadamente altas que se observan en aerobiose nas células tumorais (o chamado efecto Warburg descrito por Otto Heinrich Warburg en 1930).