Both RAG1 molecules in the closed dimer are involved in the cooperative binding of the 12-RSS and 23-RSS intermediates with base specific interactions in the heptamer of the signal end.
Ambas as moléculas de RAG1 no dímero pechado están implicadas na unión cooperativa dos intermediarios 12-RSS e 23-RSS con interaccións específicas de base no heptámero do extremo sinal.