Moreover, FGF21 could inhibit the transcriptional levels of the key genes involved in processing and nuclear translocation of SREBP-1c, and decrease the protein amount of mature SREBP-1c.
Ademais, FGF21 podería inhibir os niveis transcricionais de xenes clave envolvidos no procesamento e translocación ao núcleo de SREBP-1c, e a diminución da cantidade de proteínas SREBP-1c maduras.