The six remaining genes, tat, rev, nef, vif, vpr, and vpu (or vpx in the case of HIV-2), are regulatory genes for proteins that control the ability of HIV to infect cells, produce new copies of virus (replicate), or cause disease.
Os seis xenes restantes, tat, rev, nef, vif, vpr, e vpu (ou vpx no caso do VIH-2), son xenes regulatorios de proteínas que controlan a capacidade do VIH de infectar células, producir novas copias do virus (replicación), ou causar a enfermidade.