This Phenylalanine residue is assisting ERCC1 to accommodate a key Phenylalanine residue from XPF (F894) and the mutation (F231L) disturbs this accommodating function.
Un residuo de fenilalanina axuda a ERCC1 a acomodar un residuo clave de fenilalanina do XPF (F894) e a mutación (F231L) altera esta función de acomodación.