A critical step towards solving the mechanism of the ATP synthase was provided by Paul D. Boyer, by his development in 1973 of the "binding change" mechanism, followed by his radical proposal of rotational catalysis in 1982.
Un paso fundamental cara á solución dos mecanismos da ATP sintase foi proporcionada por Paul D. Boyer, co seu desenvolvemento en 1973 do mecanismo de "cambio de unión", seguido pola súa radical proposta dun sistema de catálise rotacional en 1982.