He delved into the emerging art of animation with the film Little Nemo (1911), and followed its success by adapting an episode of his comic strip Dream of the Rarebit Fiend into How a Mosquito Operates.
Iniciouse na arte da animación co filme Little Nemo en 1911, e seguiu o éxito deste adaptando un episodio da súa tira cómica Dream of the Rarebit Fiend ó filme How a Mosquito Operates.