H. Robert Horvitz initially established the importance of caspases in apoptosis and found that the ced-3 gene is required for the cell death that took place during the development of the nematode C. elegans.
Robert Horvitz estableceu inicialmente a importancia das caspases na apoptose e encontrou que se requiría o xene ced-3 para a morte celular que ten lugar durante o desenvolvemento do nematodo C. elegans.