In the absence of p53, PMS2-deficient and PMS2-proficient cells are still capable of arresting the cell cycle at the G2/M checkpoint when treated with cisplatin.
En ausencia de p53, as células deficientes en PMS2 e as proficientes en PMS2 aínda poden deter o ciclo celular no punto de control G2/M cando son tratadas con cisplatino.