In addition, genetic syndromes in which an individual is predisposed to breakage of chromosomes (chromosome instability syndromes) are frequently associated with increased risk for various types of cancer, thus highlighting the role of somatic aneuploidy in carcinogenesis.
Ademais, as síndromes xenéticas nas que o individuo está predisposto á rotura dos cromosomas (síndromes de inestabilidade cromosómica) están asociados frecuentemente cun incremento do risco de ter varios tipos de cancro, o que subliña o papel da aneuploidía somática na carcinoxénese.