The Spanish took over the region in the Treaty of Paris in 1763, but were not to play a major role in the area other than taxing and licensing all traffic on the Missouri River.
España fíxose cargo da rexión trala firma do Tratado de París de 1763, pero non xogaron un papel importante na zona á parte do cobro de impostos e a concesión de licenzas para o tráfico no río Missouri.