Although homodimers of p50 and p52 are, in general, repressors of κB site transcription, both p50 and p52 participate in target gene transactivation by forming heterodimers with RelA, RelB, or c-Rel.
Aínda que os homodímeros de p50 e p52 son, en xeral, represores da transcrición do sitio κB, ambos os dous (p50 e p52) participan na transactivación de xenes diana formando heterodímeros con RelA, RelB, ou c-Rel.