According to this classification, N6-MTases that have a DPPY motif (CM II) occurring after the FxGxG motif (CM I) are designated D12 class N6-adenine MTases.
Segundo esta clasificación, as N6-MTases que teñen un motivo DPPY (CM II) que aparece despois do motivo FxGxG (CM I) denomínanse N6-adenina MTases de clase D12.