Within Herpesviridae, CMV belongs to the Betaherpesvirinae subfamily, which also includes the genera Muromegalovirus and Roseolovirus (HHV-6 and HHV-7).
Dentro dos Herpesviridae, os CMV pertencen á subfamilia Betaherpesvirinae, na que tamén están incluídos os xéneros Muromegalovirus e Roseolovirus (HHV-6 e HHV-7).