It has been proposed that Aurora B localization is important for its function: as it is located in the inner region of the kinetochore (in the centromeric heterochromatin), when the centromeric tension is established sister kinetochores separate, and Aurora B cannot reach its substrates, so that kMTs are stabilized.
Propúxose que a localización da Aurora B é importante para a súa función: ao encontrarse na zona interna do cinetocoro (na heterocromatina centromérica), cando se establece tensión centromérica os cinetocoros irmáns afástanse, e a Aurora B non pode acadar os seus substratos, de maneira que os kMTs se estabilizan.