Following the announcement of the album's title and cover on February 2, 2011, Spears said about Femme Fatale: I've poured my heart and soul into this album over the last 2 years.
Julkaistuaan albumin nimen ja kansikuvan 2. helmikuuta 2011 Spears twiittasi albumistaan sanoen: I've poured my heart and soul into this album over the last 2 years.