Question: Which catastrophic event in 1876, in Brooklyn, resulted in the death of 278 individuals and which destroyed the former Park Theatre, leased to Sarah Crocker Conway at that time but who continued in the lease on the new building in which her husband played leading parts?

Context articles: Harold Crocker
Sarah Crocker Conway
Fritz Delius (actor)
Brooklyn Theatre fire
Great Fire of Warwick
Abbey's Park Theatre
Park Theatre (Brooklyn)
Conway Tearle
Chromothripsis
Frederick B. Conway

After a successful career as a Queensland and then Australian international representative, in the 1954 pre-season Crocker signed a then record one-season deal for an Australian to move south and play for Sydney club Parramatta in order to assist his family who had lost their home in a fire the previous year.
 Parramatta finished the 1954 NSWRFL season with the wooden spoon however.
 In the post season Crocker was selected for the Australian national team's campaign for the 1954 Rugby League World Cup tournament, the first ever, which was held in France.
 Crocker didn't play in the Kangaroos' first match which was lost to Great Britain, but was selected as a second-row forward for the second match against New Zealand which Australia won.
 He played in the third match against France which the Australians lost, meaning they would fail to reach the final.
 He is listed on the Australian Players Register as Kangaroo No. 278.
 The following season was Crocker's last in the NSWRFL Premiership's first grade.
Sarah Crocker Conway (b. Ridgefield, Connecticut, 1834; d. Brooklyn, New York, April 28, 1875) was an actress.
 She was a sister of Elizabeth Crocker Bowers, also an actress.
 She made her debut in Baltimore, Maryland in 1849, playing Parthenia and other leading parts.
 In May 1852, she married the actor Frederick B. Conway, and the two thenceforward acted together.
 In 1859, they opened Pike's Opera House in Cincinnati, Ohio with a first-class company, but the engagement was not profitable, and they returned to the east.
 In 1861, they visited England, and filled a short engagement at Sadler's Wells Theatre, London.
 After their return, they became star actors, and made an extensive and profitable tour.
 In 1864 Sarah leased the Park Theatre in Brooklyn, and subsequently the new Brooklyn Theatre, in which for nine years her husband played leading parts.
 Sarah Conway possessed a tall and graceful figure and an expressive countenance, and was a versatile actress and a popular theatre manager.
Fritz Delius (28 September 1890 20 September 1966) was a German film actor and theater artist.
 He played leading parts opposite Henny Porten and Fern Andra in several silent films.
 After the advent of talkies he shifted his focus to theater.
 When Adolf Hitler came to power and several restrictions began to be imposed on Jews, Delius emigrated to Switzerland where he continued his theater and film career.
The Brooklyn Theatre Fire was a catastrophic theatre fire that broke out on the evening of December 5, 1876, in the then-city of Brooklyn (now a borough of New York City).
 The conflagration killed at least 278 individuals, with some accounts reporting more than 300 dead.
 One hundred and three unidentified victims were interred in a common grave at Green-Wood Cemetery.
 An obelisk near the main entrance at Fifth Avenue and 25th Street marks the burial site.
 More than two dozen identified victims were interred individually in separate sections at the Cemetery of the Evergreens in Brooklyn.
The Great Fire of Warwick was a major conflagration that swept through the small town of Warwick, England, beginning at 2:00 p.m. on 5 September 1694 and lasting for six hours.
 The fire started from a spark from a torch that was being carried up High Street.
 The town’s small population, the close-packed nature of the environment, and the amount of combustible building material all lead to the fire’s start and spread, and the limited fire-fighting methods of the time helped transform the small torch fire into a catastrophic event.
Abbey's Park Theatre or Abbey's New Park Theatre was a playhouse at 932 Broadway and 22nd Street, New York City.
 It opened as the New Park Theatre in 1874, and was in use until 1882 when it burned down and was never rebuilt as a theatre.
The Park Theatre was a playhouse in Brooklyn, New York City, located on Fulton Street.
 Built in 1860 and opened in 1863, the Park Theatre was the oldest playhouse in Brooklyn until it was destroyed by fire on November 12, 1908.
Frederick Conway Levy was born on May 17, 1878, in New York City, the son of the well-known British-born cornetist Jules Levy (1838–1903) and American actress Marianne “Minnie” Conway (1852–1896).
 Tearle also had a sister, and a half-brother, musician Jules Levy, Jr., from his father's previous marriage.
 Minnie's mother was stage actress Sarah Crocker Conway.
 Minnie Conway was a direct descendant of William Augustus Conway, a British Shakespearian actor who became popular in America during the 1820s.
 Her father, the proprietor of the Brooklyn Theatre, was said to have organized the first stock company in America.
 After Tearle’s parents separated, his mother married Osmond Tearle (1852–1901), a British Shakespearian actor popular in “the provinces”.
 Two half brothers, Godfrey and Malcolm Tearle, were born from Marianne's marriage to Osmond Tearle.
Chromothripsis is the phenomenon by which up to thousands of clustered chromosomal rearrangements occur in a single event in localised and confined genomic regions in one or a few chromosomes, and is known to be involved in both cancer and congenital diseases.
 It occurs through one massive genomic rearrangement during a single catastrophic event in the cell's history.
 It is believed that for the cell to be able to withstand such a destructive event, the occurrence of such an event must be the upper limit of what a cell can tolerate and survive.
 The chromothripsis phenomenon opposes the conventional theory that cancer is the gradual acquisition of genomic rearrangements and somatic mutations over time.
Frederick Bartlett Conway (b. Clifton, 10 February 1819; d. Manchester, Massachusetts, 6 September 1874) was an actor.
 He was the son of William A. Conway.
 He early developed a taste for the stage.
 After he had won a fair position in his profession in England, he came to the United States in August 1850.
 Here he formed an association with Edwin Forrest, and played Iago to his "Othello", de Mauprat to his "Richelieu", and other companion parts.
 After the death of his first wife, Mr. Conway married, in May, 1852, Sarah Crocker, a leading actress, and the two thenceforward acted together.
 In 1859 they opened Pike's Opera House in Cincinnati, Ohio with a first-class company, but the engagement was not profitable, and they returned to the east.
 In 1861, they visited England, and filled a short engagement at Sadler's Wells Theatre, London.
 After their return they became star actors, and made an extensive and profitable tour.
 Though somewhat pompous in manner, Frederick Conway was a good actor, with a fine personal appearance and a commanding delivery.
 He was the father of Marianne "Minnie" Conway and Lilian Conway.
 His grandsons, Minnie's sons, were actors Conway Tearle and Godfrey Tearle.