Question: "The End of Serialization as We Know It" is the tenth episode and the season finale in the twentieth season of which American animated sitcom, that premiered on Comedy Central on September 14, 2016?

Context articles: Insecurity (South Park)
Member Berries
The End of Serialization as We Know It
Skank Hunt
PC Principal Final Justice
South Park (season 15)
Rehash (South Park)
South Park (season 20)
Desperate Housewives (season 2)
HappyHolograms

"Insecurity" is the tenth episode of the sixteenth season of the American animated sitcom "South Park", and the 233rd episode of the series overall.
 It aired on Comedy Central in the United States on October 10, 2012.
"Member Berries" is the first episode in the twentieth season of the American animated television series "South Park".
 The 268th episode of the series overall, it premiered on Comedy Central in the United States on September 14, 2016.
"The End of Serialization as We Know It" is the tenth episode and the season finale in the twentieth season of the American animated television series "South Park".
 The 277th episode of the series overall, it first aired on Comedy Central in the United States on December 7, 2016.
"Skank Hunt" is the second episode in the twentieth season of the American animated television series "South Park".
 The 269th episode of the series overall, it first aired on Comedy Central in the United States on September 21, 2016.
 The episode parodied trolling, cyberbullying and suicide prevention.
"PC Principal Final Justice" (also known as "PC Principal") is the tenth and final episode of the nineteenth season and the 267th overall episode of the animated television series "South Park", written and directed by series co-creator Trey Parker.
 The episode premiered on Comedy Central on December 9, 2015.
 It is the third and final part of a three-episode story arc that began with the episode "Sponsored Content" and continued in the episode "Truth and Advertising", which collectively serve as the season finale.
 The episode parodies the abundance of online advertising, as well as gun politics in the United States, as part of its season-long lampoon of political correctness.
The fifteenth season of the American animated sitcom "South Park" began airing on Comedy Central on April 27, 2011 and ended on November 16, 2011.
 In response to reactions to the mid-season finale episode "You're Getting Old", which seemed to insinuate that creators Trey Parker and Matt Stone were wrapping up the series, Comedy Central proclaimed through the media that "South Park" was renewed for two more seasons, and the duo were signed through 2013.
 Shortly before the airing of the season finale episode "The Poor Kid", "South Park" was extended again until 2016, taking the show to 20 seasons.
 Parker was the director and writer for all episodes, and Robert Lopez was the writer in this eleventh episode for the fifteenth season.
"#REHASH" is the ninth episode in the eighteenth season of the American animated television series "South Park".
 The 256th overall episode, it was written and directed by series co-creator and co-star Trey Parker.
 The episode premiered on Comedy Central in the United States on December 3, 2014.
 The episode is part one of the two-part season finale.
 The episode lampoons the popularity of Internet Let's Play celebrities and the phenomena of Internet trending topics that lack actual relevance.
 The episode also references and intertwined multiple elements from previous episodes in the eighteenth season of "South Park".
 YouTube celebrity PewDiePie plays himself in this episode.
The twentieth season of the American animated sitcom "South Park" premiered on Comedy Central on September 14, 2016 and ended on December 7, 2016, containing ten episodes.
 As with most seasons of the show, all episodes are written and directed by series co-creator and co-star Trey Parker.
The second season of the American dramedy-mystery television series "Desperate Housewives" commenced airing in the United States on September 25, 2005 and concluded on May 21, 2006.
 The season continues the story of the Wisteria Lane residents, while their seemingly perfect lives in the suburban neighborhood are shaken by the arrival of the mysterious Betty Applewhite.
 Broadcast in the Sunday night time slot at 9.00 ET, the season aired twenty-four regular episodes, including a two-part season finale.
 In addition, three clip shows were produced for the season, in order to put the previous events of the show in perspective. "
All the Juicy Details" aired before the eleventh episode, detailing the most memorable events of the season's first half, whereas "The More You Know, The Juicier It Gets", which aired before the twentieth episode, prepared the viewers for the highly anticipated season finale. "
Time to Come Clean" aired three weeks before the inception of the third season, and reviewed the previous mysteries of the series before introducing the new story lines.
 The second season had fourteen roles receiving star billing, out of whom eleven were part of the first season's main cast.
 The main story lines of the season were Susan Mayer's relationship with her former husband, Gabrielle Solis' upcoming motherhood, Lynette Scavo's return to work and the death of Bree Van de Kamp's husband.
"#HappyHolograms" is the tenth and final episode in the eighteenth season of the American animated television series "South Park".
 The 257th episode overall, it was written and directed by series co-creator and co-star Trey Parker.
 The episode premiered on Comedy Central in the United States on December 10 2014.
 It is the second part of the two-part season finale which began with the previous episode, "#REHASH".
 The episode makes multiple references to earlier episodes over the season, as well as to previous seasons, while mainly lampooning the trend of culture constantly making trending topics with no actual relevance.
 It also lampoons news events such as the death of Eric Garner, the shooting of Michael Brown, the sexual assault allegations against Bill Cosby, and the use of celebrity holograms.
 YouTube celebrity PewDiePie appeared as himself, continuing his story line from the previous episode.