Question: This medicine was marketed with a Spokestoon to minor aches, pains, inflammation, fever, headache, heartburn, stomachache, indigestion, acid reflux and hangovers, while neutralizing excess stomach acid.

Context articles: Angle of His
Gastroesophageal reflux disease
Bilious vomiting syndrome
Spokestoon
Hiatus hernia
Angelic acid
Tums
Wet burp
Collis gastroplasty
Alka-Seltzer

The angle of His is the acute angle created between the cardia at the entrance to the stomach, and the esophagus.
 It forms a valve, preventing reflux of duodenal bile, enzymes and stomach acid from entering the esophagus, where they can cause inflammation.
 The angle is created by the collar sling fibres and the circular muscles around this (gastroesophageal) junction.
 The angle of His is normally undeveloped in infancy, with the esophagus making a vertical junction with the stomach, and as a result, reflux of stomach contents is common.
Gastroesophageal reflux disease (GERD), also known as acid reflux, is a long-term condition where stomach contents come back up into the esophagus resulting in either symptoms or complications.
 Symptoms include the taste of acid in the back of the mouth, heartburn, bad breath, chest pain, vomiting, breathing problems, and wearing away of the teeth.
 Complications include esophagitis, esophageal strictures, and Barrett's esophagus.
Bilious vomiting syndrome in dogs is vomiting in response to bile-induced inflammation of the stomach.
 It is also known as reflux gastritis syndrome and duodenal-gastric reflux.
 Bile salts interfere with the gastric mucosal barrier, allowing acid to irritate the stomach lining and cause gastritis.
A spokestoon is an established cartoon character who is hired to endorse a product.
 It should not be equated with a cartoon character invented specifically to give identity to a product, such as the Michelin Man, Speedy Alka-Seltzer or the Pillsbury Doughboy.
 For these and more, see List of advertising characters.
A hiatus hernia is a type of hernia in which abdominal organs (typically the stomach) slip through the diaphragm into the middle compartment of the chest.
 This may result in gastroesophageal reflux disease (GERD) or laryngopharyngeal reflux (LPR) with symptoms such as a taste of acid in the back of the mouth or heartburn.
 Other symptoms may include trouble swallowing and chest pains. Complications may include iron deficiency anemia, volvulus, or bowel obstruction.
Angelic acid is a monocarboxylic unsaturated organic acid.
 It is mostly found in the plants of the family Apiaceae.
 German pharmacist Ludwig Andreas Buchner isolated angelic acid in 1842 from the roots of garden angelica ("Angelica archangelica") which gave the acid its name.
 Angelic acid is a volatile solid with a biting taste and pungent sour odor.
 It is the "cis" isomer of 2-methyl-2-butenoic acid, which easily converts to the "trans" isomer, tiglic acid, upon heating or reaction with inorganic acids.
 The reverse transformation occurs much less readily.
 The salts and esters of angelic acid are called angelates.
 Angelic acid esters are the active components of herbal medicine used against a wide range of various health disturbances including pains, fever, gout, heartburn, etc.
Tums is an antacid made of sucrose (sugar) and calcium carbonate (CaCO) manufactured by GlaxoSmithKline in St. Louis, Missouri, USA.
 They are also available in a sugar free version.
 It is an over-the-counter drug, available at many retail stores, including drug stores, grocery stores and mass merchandisers.
 It provides relief from acid indigestion, heartburn, and indigestion ("sour stomach").
A wet burp is a slang term for a burp where small amounts of liquid are regurgitated.
 It is similar to vomiting—one who experiences a wet burp often has an acidic/burning sensation in the mouth, which can be displeasurable.
 In addition to the cause of this typically being related to acid reflux disease, it also occurs if an individual consumes too much food for the stomach to handle.
 This results in the partially digested contents of the stomach to back up into the esophageal canal, which may cause small amounts of the bile and food to come up during the burp.
 This may also be accompanied by excessive, deep burping.
 Wet burping can also take place if someone consumes food too quickly, resulting in air being trapped throughout the stomach's chyme.
 When the air is released, it carries small amounts of chyme with it.
A Collis gastroplasty is a surgical procedure performed when the surgeon desires to create a Nissen fundoplication, but the portion of esophagus inferior to the diaphragm is too short.
 Thus, there is not enough esophagus to wrap.
 A vertical incision is made in the stomach parallel to the left border of the esophagus.
 This effectively lengthens the esophagus.
 The stomach fundus can then be wrapped around the neo-esophagus, thus reducing reflux of stomach acid into the esophagus.
Alka-Seltzer is an effervescent antacid and pain reliever first marketed by the Dr. Miles Medicine Company of Elkhart, Indiana, United States.
 It was developed by head chemist Maurice Treneer.
 Alka-Seltzer is marketed for relief of minor aches, pains, inflammation, fever, headache, heartburn, stomachache, indigestion, acid reflux and hangovers, while neutralizing excess stomach acid.
 It was launched in 1931.
 A spin-off of Alka-Seltzer made to relieve colds and flu, Alka-Seltzer Plus, was later introduced.
 A short-lived antacid non-aspirin variant, Alka-Mints, was introduced in 1994 and discontinued in 1997.
 Another non-aspirin-based variant, Alka-Seltzer Gold, was later released.