Question: The One-Million-Liter Test Sphere — also known as the Test Sphere, the Horton Test Sphere, the Cloud Study Chamber, Building 527, and the “Eight Ball” (or “8-ball”) — is a decommissioned biological warfare (BW) chamber and testing facility located on which United States Army Medical Command installation located in Frederick, Maryland?

Context articles: United States biological defense program
Fort Detrick
Dwight D. Eisenhower Army Medical Center
Eric Schoomaker
Building 257
Kevin C. Kiley
Tripler Army Medical Center
Biological warfare
Ted Wong (general)
One-Million-Liter Test Sphere

The United States biological defense program — in recent years also called the National Biodefense Strategy — began as a small defensive effort that paralleled the country's offensive biological weapons development and production program, active between 1943 and 1969.
 Organizationally, the medical defense research effort was pursued first (1956-1969) by the U.S. Army Medical Unit (USAMU) and later, after the discontinuation of the offensive program, by the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID).
 Both of these units were located at Fort Detrick, Maryland, where the U.S. Army Biological Warfare Laboratories were headquartered.
 The current mission is multi-agency, not exclusively military, and is purely to develop defensive measures against bio-agents, as opposed to the former bio-weapons development program.
Fort Detrick is a United States Army Medical Command installation located in Frederick, Maryland.
 Historically, Fort Detrick was the center of the US biological weapons program from 1943 to 1969.
 Since the discontinuation of that program, it has hosted most elements of the United States biological defense program.
The Dwight D. Eisenhower Army Medical Center (EAMC) is a 93-bed medical treatment facility located on Fort Gordon, Ga., located near Augusta, Georgia that previously served as the headquarters of the Army's Southeast Regional Medical Command (SERMC).
 SERMC oversaw the Army's hospitals and clinics within the southeastern United States and Puerto Rico.
 SERMC was renamed Southern Regional Medical Command (SRMC) and was relocated to San Antonio in 2009.
Eric B. Schoomaker (born September 15, 1948) is a former United States Army lieutenant general who served as the 42nd Surgeon General of the United States Army and Commanding General, United States Army Medical Command, and a practicing hematologist.
 He previously served as Commanding General, North Atlantic Regional Medical Command and Walter Reed Army Medical Center.
 He assumed the post of U.S. Army Surgeon General on December 11, 2007.
Building 257, also known as Lab 257, was a United States biological warfare research laboratory located at Fort Terry on Plum Island, New York.
 Originally intended for munitions storage, the facility researched anti-animal biological agents beginning in 1952 under the United States Army.
 Biological warfare research continued in the building under the United States Department of Agriculture (USDA) until a new laboratory was completed.
Major General (Ret.)
 Kevin C. Kiley (born October 18, 1950) was the 41st Surgeon General of the United States Army and commander of the U.S. Army Medical Command, Fort Sam Houston, Texas.
 He was commander of Walter Reed Army Medical Center and North Atlantic Regional Medical Command twice, from 2002 to 2004, and as acting commander, March 1–2, 2007.
 He submitted his request to retire from the U.S. Army on March 11, 2007, in the wake of the Walter Reed Army Medical Center neglect scandal, and was removed from his nominative billet as a Lieutenant General.
 Pending retirement, he was assigned to a temporary billet at the General Officer Management Office at the Pentagon in the grade Major General.
 His retirement in the grade of Major General was subsequently approved.
Tripler Army Medical Center is the headquarters of the Pacific Regional Medical Command of the armed forces administered by the United States Army in the state of Hawaii.
 It is the largest military hospital in the Asian and Pacific Rim region and serves a military sphere of jurisdiction that spans over 52% of the Earth's surface.
 Located on the slopes of Moanalua Ridge overlooking the Honolulu neighborhoods of Moanalua and Salt Lake, Tripler Army Medical Center's massive coral pink structure can be seen from any point in the Honolulu District.
Biological warfare (BW)—also known as germ warfare—is the use of biological toxins or infectious agents such as bacteria, viruses, and fungi with the intent to kill or incapacitate humans, animals or plants as an act of war.
 Biological weapons (often termed "bio-weapons", "biological threat agents", or "bio-agents") are living organisms or replicating entities (viruses, which are not universally considered "alive") that reproduce or replicate within their host victims.
 Entomological (insect) warfare is also considered a type of biological weapon.
 This type of warfare is distinct from nuclear warfare and chemical warfare, which together with biological warfare make up NBC, the military acronym for nuclear, biological, and chemical warfare using weapons of mass destruction (WMDs).
 None of these are conventional weapons, which are deployed primarily for their explosive, kinetic, or incendiary potential.
M. Ted Wong is a retired major general in the United States Army.
 General Wong commanded the Northern Regional Medical Command, a unit of the United States Army Medical Command.
 He was also Chief of the U.S. Army Dental Corps.
 He previously commanded the Southern Regional Medical Command.
The One-Million-Liter Test Sphere — also known as the Test Sphere, the Horton Test Sphere, the Cloud Study Chamber, Building 527, and the “Eight Ball” (or “8-ball”) — is a decommissioned biological warfare (BW) chamber and testing facility located on Fort Detrick, Maryland, USA.
 It was constructed and utilized by the U.S. Army Biological Warfare Laboratories as part of its BW research program from 1951 to 1969.
 It is the largest aerobiology chamber ever constructed and was placed on the National Register of Historic Places in 1977.