sarnsrun/medquad huggingface dataset:
Topic: Chronic Myeloproliferative Neoplasms
Question: How to diagnose Chronic Myeloproliferative Neoplasms ?
Answer: Tests that examine the blood and bone marrow are used to detect (find) and diagnose chronic myeloproliferative neoplasms. The following tests and procedures may be used:         -   Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patients health habits and past illnesses and treatments will also be taken.    -   Complete blood count (CBC) with differential : A procedure in which a sample of blood is drawn and checked for the following:                - The number of red blood cells and platelets.       - The number and type of white blood cells.      - The amount of hemoglobin (the protein that carries oxygen) in the red blood cells.       - The portion of the blood sample made up of red blood cells.              -   Peripheral blood smear : A procedure in which a sample of blood is checked for the following:                - Whether there are red blood cells shaped like teardrops.      - The number and kinds of white blood cells.      - The number of platelets.      - Whether there are blast cells.              -   Blood chemistry studies : A procedure in which a blood sample is checked to measure the amounts of certain substances released into the blood by organs and tissues in the body. An unusual (higher or lower than normal) amount of a substance can be a sign of disease.    -   Bone marrow aspiration and biopsy : The removal of bone marrow, blood, and a small piece of bone by inserting a hollow needle into the hipbone or breastbone. A pathologist views the bone marrow, blood, and bone under a microscope to look for abnormal cells.    -   Cytogenetic analysis : A test in which cells in a sample of blood or bone marrow are viewed under a microscope to look for certain changes in the chromosomes. Certain diseases or disorders may be diagnosed or ruled out based on the chromosomal changes.    -   Gene mutation test: A laboratory test done on a bone marrow or blood sample to check for mutations in  JAK2 ,  MPL , or  CALR genes. A JAK2 gene mutation is often found in patients with polycythemia vera, essential thrombocythemia, or primary myelofibrosis. MPL or CALR gene mutations are found in patients with essential thrombocythemia or primary myelofibrosis.
Source: CancerGov
Topic: Chronic Myeloproliferative Neoplasms
Question: What are the stages of Chronic Myeloproliferative Neoplasms ?
Answer: Key Points
                    - There is no standard staging system for chronic myeloproliferative neoplasms.
                
                
                    There is no standard staging system for chronic myeloproliferative neoplasms.
                    Staging is the process used to find out how far the cancer has spread. There is no standard staging system for chronic myeloproliferative neoplasms. Treatment is based on the type of myeloproliferative neoplasm the patient has. It is important to know the type in order to plan treatment.
Source: CancerGov
Topic: Parathyroid Cancer
Question: What is (are) Parathyroid Cancer ?
Answer: Key Points
                    - Parathyroid cancer is a rare disease in which malignant (cancer) cells form in the tissues of a parathyroid gland.    - Having certain inherited disorders can increase the risk of developing parathyroid cancer.     - Signs and symptoms of parathyroid cancer include weakness, feeling tired, and a lump in the neck.    - Tests that examine the neck and blood are used to detect (find) and diagnose parathyroid cancer.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Parathyroid cancer is a rare disease in which malignant (cancer) cells form in the tissues of a parathyroid gland.
                    The parathyroid glands are four pea-sized organs found in the neck near the thyroid gland. The parathyroid glands make parathyroid hormone (PTH or parathormone). PTH helps the body use and store calcium to keep the calcium in the blood at normal levels.     A parathyroid gland may become overactive and make too much PTH, a condition called hyperparathyroidism. Hyperparathyroidism can occur when a benign tumor (noncancer), called an adenoma, forms on one of the parathyroid glands, and causes it to grow and become overactive. Sometimes hyperparathyroidism can be caused by parathyroid cancer, but this is very rare.   The extra PTH causes:          - The calcium stored in the bones to move into the blood.    - The intestines to absorb more calcium from the food we eat.        This condition is called hypercalcemia (too much calcium in the blood).   The hypercalcemia caused by hyperparathyroidism is more serious and life-threatening than parathyroid cancer itself and treating hypercalcemia is as important as treating the cancer.
Source: CancerGov
Topic: Parathyroid Cancer
Question: Who is at risk for Parathyroid Cancer? ?
Answer: Having certain inherited disorders can increase the risk of developing parathyroid cancer. Anything that increases the chance of getting a disease is called a risk factor. Risk factors for parathyroid cancer include the following rare disorders that are inherited (passed down from parent to child):          -  Familial isolated hyperparathyroidism (FIHP).    -  Multiple endocrine neoplasia type 1 (MEN1) syndrome.        Treatment with radiation therapy may increase the risk of developing a parathyroid adenoma.
Source: CancerGov
Topic: Parathyroid Cancer
Question: What are the symptoms of Parathyroid Cancer ?
Answer: Signs and symptoms of parathyroid cancer include weakness, feeling tired, and a lump in the neck. Most parathyroid cancer signs and symptoms are caused by the hypercalcemia that develops. Signs and symptoms of hypercalcemia include the following:         -  Weakness.    - Feeling very tired.    -  Nausea and vomiting.    - Loss of appetite.    - Weight loss for no known reason.    - Being much more thirsty than usual.    -  Urinating much more than usual.    -  Constipation.    - Trouble thinking clearly.        Other signs and symptoms of parathyroid cancer include the following:         - Pain in the abdomen, side, or back that doesn't go away.    - Pain in the bones.    - A broken bone.    - A lump in the neck.    - Change in voice such as hoarseness.    - Trouble swallowing.        Other conditions may cause the same signs and symptoms as parathyroid cancer. Check with your doctor if you have any of these problems.
Source: CancerGov
Topic: Parathyroid Cancer
Question: What is the outlook for Parathyroid Cancer ?
Answer: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - Whether the calcium level in the blood can be controlled.    - The stage of the cancer.     - Whether the tumor and the capsule around the tumor can be completely removed by surgery.     - The patient's general health.
Source: CancerGov
Topic: Parathyroid Cancer
Question: what research (or clinical trials) is being done for Parathyroid Cancer ?
Answer: New types of treatment are being tested in clinical trials.
                    Information about clinical trials is available from the NCI website.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
Source: CancerGov
Topic: Lip and Oral Cavity Cancer
Question: What is (are) Lip and Oral Cavity Cancer ?
Answer: Key Points
                    - Lip and oral cavity cancer is a disease in which malignant (cancer) cells form in the lips or mouth.    - Tobacco and alcohol use can affect the risk of lip and oral cavity cancer.     - Signs of lip and oral cavity cancer include a sore or lump on the lips or in the mouth.     - Tests that examine the mouth and throat are used to detect (find), diagnose, and stage lip and oral cavity cancer.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Lip and oral cavity cancer is a disease in which malignant (cancer) cells form in the lips or mouth.
                    The oral cavity includes the following:         - The front two thirds of the tongue.    - The gingiva (gums).    - The buccal mucosa (the lining of the inside of the cheeks).    - The floor (bottom) of the mouth under the tongue.    - The hard palate (the roof of the mouth).    - The retromolar trigone (the small area behind the wisdom teeth).          Most lip and oral cavity cancers start in squamous cells, the thin, flat cells that line the lips and oral cavity. These are called squamous cell carcinomas. Cancer cells may spread into deeper tissue as the cancer grows. Squamous cell carcinoma usually develops in areas of leukoplakia (white patches of cells that do not rub off).    Lip and oral cavity cancer is a type of head and neck cancer.
Source: CancerGov
Topic: Lip and Oral Cavity Cancer
Question: Who is at risk for Lip and Oral Cavity Cancer? ?
Answer: Tobacco and alcohol use can affect the risk of lip and oral cavity cancer. Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer. Talk with your doctor if you think you may be at risk. Risk factors for lip and oral cavity cancer include the following:         - Using tobacco products.    - Heavy alcohol use.    - Being exposed to natural sunlight or artificial sunlight (such as from tanning beds) over long periods of time.    - Being male.
Source: CancerGov
Topic: Lip and Oral Cavity Cancer
Question: What are the symptoms of Lip and Oral Cavity Cancer ?
Answer: Signs of lip and oral cavity cancer include a sore or lump on the lips or in the mouth. These and other signs and symptoms may be caused by lip and oral cavity cancer or by other conditions. Check with your doctor if you have any of the following:          - A sore on the lip or in the mouth that does not heal.    - A lump or thickening on the lips or gums or in the mouth.    - A white or red patch on the gums, tongue, or lining of the mouth.    - Bleeding, pain, or numbness in the lip or mouth.    - Change in voice.    - Loose teeth or dentures that no longer fit well.    - Trouble chewing or swallowing or moving the tongue or jaw.    - Swelling of jaw.    - Sore throat or feeling that something is caught in the throat.        Lip and oral cavity cancer may not have any symptoms and is sometimes found during a regular dental exam.
Source: CancerGov
Topic: Lip and Oral Cavity Cancer
Question: What is the outlook for Lip and Oral Cavity Cancer ?
Answer: Certain factors affect prognosis (chance of recovery) and treatment options. Prognosis (chance of recovery) depends on the following:         - The stage of the cancer.    - Where the tumor is in the lip or oral cavity.    - Whether the cancer has spread to blood vessels.        For patients who smoke, the chance of recovery is better if they stop smoking before beginning radiation therapy.   Treatment options depend on the following:          - The stage of the cancer.    - The size of the tumor and where it is in the lip or oral cavity.    - Whether the patient's appearance and ability to talk and eat can stay the same.    - The patient's age and general health.        Patients who have had lip and oral cavity cancer have an increased risk of developing a second cancer in the head or neck. Frequent and careful follow-up is important. Clinical trials are studying the use of retinoid drugs to reduce the risk of a second head and neck cancer. Information about ongoing clinical trials is available from the NCI website.
Source: CancerGov
Topic: Lip and Oral Cavity Cancer
Question: what research (or clinical trials) is being done for Lip and Oral Cavity Cancer ?
Answer: New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Chemotherapy     Chemotherapy is a cancer treatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping the cells from dividing. When chemotherapy is taken by mouth or injected into a vein or muscle, the drugs enter the bloodstream and can reach cancer cells throughout the body (systemic chemotherapy). When chemotherapy is placed directly into the cerebrospinal fluid, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas (regional chemotherapy). The way the chemotherapy is given depends on the type and stage of the cancer being treated.       Hyperfractionated radiation therapy     Hyperfractionated radiation therapy is radiation treatment in which the total dose of radiation is divided into small doses and the treatments are given more than once a day.        Hyperthermia therapy     Hyperthermia therapy is a treatment in which body tissue is heated above normal temperature to damage and kill cancer cells or to make cancer cells more sensitive to the effects of radiation and certain anticancer drugs.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
Source: CancerGov
Topic: Prostate Cancer
Question: What is (are) Prostate Cancer ?
Answer: Key Points
                    - Prostate cancer is a disease in which malignant (cancer) cells form in the tissues of the prostate.    - Prostate cancer is the second most common cancer among men in the United States.
                
                
                    Prostate cancer is a disease in which malignant (cancer) cells form in the tissues of the prostate.
                    The prostate is a gland in the male reproductive system. The prostate is just below the bladder (the organ that collects and empties urine) and in front of the rectum (the lower part of the intestine). It is about the size of a walnut and surrounds part of the urethra (the tube that empties urine from the bladder). The prostate gland produces fluid that makes up part of the semen.       As men age, the prostate may get bigger. A bigger prostate may block the flow of urine from the bladder and cause problems with sexual function. This condition is called benign prostatic hyperplasia (BPH). BPH is not cancer, but surgery may be needed to correct it. The symptoms of BPH or of other problems in the prostate may be like symptoms of prostate cancer.
Source: CancerGov
Topic: Prostate Cancer
Question: Who is at risk for Prostate Cancer? ?
Answer: Prostate cancer is most common in older men. In the U.S., about one out of five men will be diagnosed with prostate cancer. Most men diagnosed with prostate cancer do not die of it.    See the following PDQ summaries for more information about prostate cancer:         -  Prostate Cancer Screening     -  Prostate Cancer Treatment
Source: CancerGov
Topic: Prostate Cancer
Question: what research (or clinical trials) is being done for Prostate Cancer ?
Answer: Cancer prevention clinical trials are used to study ways to prevent cancer.
                    Cancer prevention clinical trials are used to study ways to lower the risk of developing certain types of cancer. Some cancer prevention trials are conducted with healthy people who have not had cancer but who have an increased risk for cancer. Other prevention trials are conducted with people who have had cancer and are trying to prevent another cancer of the same type or to lower their chance of developing a new type of cancer. Other trials are done with healthy volunteers who are not known to have any risk factors for cancer.    The purpose of some cancer prevention clinical trials is to find out whether actions people take can prevent cancer. These may include eating fruits and vegetables, exercising, quitting smoking, or taking certain medicines, vitamins, minerals, or food supplements.
                
                
                    New ways to prevent prostate cancer are being studied in clinical trials.
                    Clinical trials are taking place in many parts of the country. Information about clinical trials can be found in the Clinical Trials section of the NCI website. Check NCI's list of cancer clinical trials for prostate cancer prevention trials that are accepting patients.
Source: CancerGov
Topic: Childhood Craniopharyngioma
Question: What is (are) Childhood Craniopharyngioma ?
Answer: Key Points
                    - Childhood craniopharyngiomas are benign brain tumors found near the pituitary gland.    - There are no known risk factors for childhood craniopharyngioma.    - Signs of childhood craniopharyngioma include vision changes and slow growth.    - Tests that examine the brain, vision, and hormone levels are used to detect (find) childhood craniopharyngiomas.    - Childhood craniopharyngiomas are diagnosed and may be removed in the same surgery.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Childhood craniopharyngiomas are benign brain tumors found near the pituitary gland.
                    Childhood craniopharyngiomas are rare tumors usually found near the pituitary gland (a pea-sized organ at the bottom of the brain that controls other glands) and the hypothalamus (a small cone-shaped organ connected to the pituitary gland by nerves).     Craniopharyngiomas are usually part solid mass and part fluid -filled cyst. They are benign (not cancer) and do not spread to other parts of the brain or to other parts of the body. However, they may grow and press on nearby parts of the brain or other areas, including the pituitary gland, the optic chiasm, optic nerves, and fluid-filled spaces in the brain. Craniopharyngiomas may affect many functions of the brain. They may affect hormone making, growth, and vision. Benign brain tumors need treatment.    This summary is about the treatment of primary brain tumors (tumors that begin in the brain). Treatment for metastatic brain tumors, which are tumors formed by cancer cells that begin in other parts of the body and spread to the brain, is not covered in this summary. See the PDQ treatment summary on Childhood Brain and Spinal Cord Tumors Treatment Overview for information about the different types of childhood brain and spinal cord tumors.   Brain tumors can occur in both children and adults; however, treatment for children may be different than treatment for adults. (See the PDQ summary on Adult Central Nervous System Tumors Treatment for more information.)
Source: CancerGov
Topic: Childhood Craniopharyngioma
Question: Who is at risk for Childhood Craniopharyngioma? ?
Answer: There are no known risk factors for childhood craniopharyngioma. Craniopharyngiomas are rare in children younger than 2 years of age and are most often diagnosed in children aged 5 to 14 years. It is not known what causes these tumors.
Source: CancerGov
Topic: Childhood Craniopharyngioma
Question: What are the symptoms of Childhood Craniopharyngioma ?
Answer: Signs of childhood craniopharyngioma include vision changes and slow growth. These and other signs and symptoms may be caused by craniopharyngiomas or by other conditions. Check with your childs doctor if your child has any of the following:         - Headaches, including morning headache or headache that goes away after vomiting.    - Vision changes.    -  Nausea and vomiting.    - Loss of balance or trouble walking.    - Increase in thirst or urination.    - Unusual sleepiness or change in energy level.    - Changes in personality or behavior.    - Short stature or slow growth.    - Hearing loss.    - Weight gain.
Source: CancerGov
Topic: Childhood Craniopharyngioma
Question: What is the outlook for Childhood Craniopharyngioma ?
Answer: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:          - The size of the tumor.    - Where the tumor is in the brain.    - Whether there are tumor cells left after surgery.    - The child's age.    -  Side effects that may occur months or years after treatment.    - Whether the tumor has just been diagnosed or has recurred (come back).
Source: CancerGov
Topic: Childhood Craniopharyngioma
Question: What are the stages of Childhood Craniopharyngioma ?
Answer: The process used to find out if cancer has spread within the brain or to other parts of the body is called staging. There is no standard system for staging childhood craniopharyngioma. Craniopharyngioma is described as newly diagnosed disease or recurrent disease. The results of the tests and procedures done to diagnose craniopharyngioma are used to help make decisions about treatment.
Source: CancerGov