sarnsrun/medquad huggingface dataset:
Topic: Urethral Cancer
Question: what research (or clinical trials) is being done for Urethral Cancer ?
Answer: New types of treatment are being tested in clinical trials.
                    Information about clinical trials is available from the NCI website.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
Source: CancerGov
Topic: Melanoma
Question: Who is at risk for Melanoma? ?
Answer: Unusual moles, exposure to sunlight, and health history can affect the risk of melanoma. Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer. Talk with your doctor if you think you may be at risk.    Risk factors for melanoma include the following:         - Having a fair complexion, which includes the following:                - Fair skin that freckles and burns easily, does not tan, or tans poorly.       - Blue or green or other light-colored eyes.       - Red or blond hair.              - Being exposed to natural sunlight or artificial sunlight (such as from tanning beds) over long periods of time.     - Being exposed to certain factors in the environment (in the air, your home or workplace, and your food and water). Some of the environmental risk factors for melanoma are radiation, solvents, vinyl chloride, and PCBs.     - Having a history of many blistering sunburns, especially as a child or teenager.     - Having several large or many small moles.    - Having a family history of unusual moles (atypical nevus syndrome).     - Having a family or personal history of melanoma.     - Being white.     - Having a weakened immune system.    - Having certain changes in the genes that are linked to melanoma.        Being white or having a fair complexion increases the risk of melanoma, but anyone can have melanoma, including people with dark skin.    See the following PDQ summaries for more information on risk factors for melanoma:         -  Genetics of Skin Cancer     -  Skin Cancer Prevention
Source: CancerGov
Topic: Melanoma
Question: What are the symptoms of Melanoma ?
Answer: Signs of melanoma include a change in the way a mole or pigmented area looks. These and other signs and symptoms may be caused by melanoma or by other conditions. Check with your doctor if you have any of the following:         - A mole that:                - changes in size, shape, or color.      - has irregular edges or borders.      - is more than one color.      - is asymmetrical (if the mole is divided in half, the 2 halves are different in size or shape).      - itches.      -  oozes, bleeds, or is ulcerated (a hole forms in the skin when the top layer of cells breaks down and the tissue below shows through).             - A change in pigmented (colored) skin.     - Satellite moles (new moles that grow near an existing mole).        For pictures and descriptions of common moles and melanoma, see Common Moles, Dysplastic Nevi, and Risk of Melanoma.
Source: CancerGov
Topic: Melanoma
Question: How to diagnose Melanoma ?
Answer: Tests that examine the skin are used to detect (find) and diagnose melanoma. If a mole or pigmented area of the skin changes or looks abnormal, the following tests and procedures can help find and diagnose melanoma:         -  Skin exam: A doctor or nurse checks the skin for moles, birthmarks, or other pigmented areas that look abnormal in color, size, shape, or texture.    -   Biopsy : A procedure to remove the abnormal tissue and a small amount of normal tissue around it. A pathologist looks at the tissue under a microscope to check for cancer cells. It can be hard to tell the difference between a colored mole and an early melanoma lesion. Patients may want to have the sample of tissue checked by a second pathologist. If the abnormal mole or lesion is cancer, the sample of tissue may also be tested for certain gene changes.        It is important that abnormal areas of the skin not be shaved off or cauterized (destroyed with a hot instrument, an electric current, or a caustic substance) because cancer cells that remain may grow and spread.    See the PDQ summary on Skin Cancer Screening for more information.
Source: CancerGov
Topic: Melanoma
Question: What is the outlook for Melanoma ?
Answer: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - The thickness of the tumor and where it is in the body.    - How quickly the cancer cells are dividing.    - Whether there was bleeding or ulceration of the tumor.     - How much cancer is in the lymph nodes.    - The number of places cancer has spread to in the body.    -  The level of lactate dehydrogenase (LDH) in the blood.    - Whether the cancer has certain mutations (changes) in a gene called BRAF.    - The patients age and general health.
Source: CancerGov
Topic: Melanoma
Question: what research (or clinical trials) is being done for Melanoma ?
Answer: New types of treatment are being tested in clinical trials.
                    Information about clinical trials is available from the NCI website
                
                
                    Treatment for melanoma may cause side effects.
                    For information about side effects caused by treatment for cancer, see our Side Effects page.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
                
                
                    Follow-up tests may be needed.
                    Some of the tests that were done to diagnose the cancer or to find out the stage of the cancer may be repeated. Some tests will be repeated in order to see how well the treatment is working. Decisions about whether to continue, change, or stop treatment may be based on the results of these tests.   Some of the tests will continue to be done from time to time after treatment has ended. The results of these tests can show if your condition has changed or if the cancer has recurred (come back). These tests are sometimes called follow-up tests or check-ups.
Source: CancerGov
Topic: Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor
Question: What is (are) Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor ?
Answer: Key Points
                    - Central nervous system atypical teratoid/rhabdoid tumor is a disease in which malignant (cancer) cells form in the tissues of the brain.    - Certain genetic changes may increase the risk of atypical teratoid/rhabdoid tumor.    - The signs and symptoms of atypical teratoid/rhabdoid tumor are not the same in every patient.    - Tests that examine the brain and spinal cord are used to detect (find) CNS atypical teratoid/rhabdoid tumor.    - Childhood atypical teratoid/rhabdoid tumor is diagnosed and may be removed in surgery.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Central nervous system atypical teratoid/rhabdoid tumor is a disease in which malignant (cancer) cells form in the tissues of the brain.
                    Central nervous system (CNS) atypical teratoid/rhabdoid tumor (AT/RT) is a very rare, fast-growing tumor of the brain and spinal cord. It usually occurs in children aged three years and younger, although it can occur in older children and adults.    About half of these tumors form in the cerebellum or brain stem. The cerebellum is the part of the brain that controls movement, balance, and posture. The brain stem controls breathing, heart rate, and the nerves and muscles used in seeing, hearing, walking, talking, and eating. AT/RT may also be found in other parts of the central nervous system (brain and spinal cord).    This summary describes the treatment of primary brain tumors (tumors that begin in the brain). Treatment for metastatic brain tumors, which are tumors formed by cancer cells that begin in other parts of the body and spread to the brain, is not covered in this summary. For more information, see the PDQ summary on Childhood Brain and Spinal Cord Tumors Treatment Overview about the different types of childhood brain and spinal cord tumors.   Brain tumors can occur in both children and adults; however, treatment for children may be different than treatment for adults. See the PDQ treatment summary on Adult Central Nervous System Tumors Treatment for more information.
Source: CancerGov
Topic: Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor
Question: Who is at risk for Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor? ?
Answer: Certain genetic changes may increase the risk of atypical teratoid/rhabdoid tumor. Anything that increases the risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk with your child's doctor if you think your child may be at risk.   Atypical teratoid/rhabdoid tumor may be linked to changes in the tumor suppressor genes SMARCB1 or SMARCA4. Genes of this type make a protein that helps control cell growth. Changes in the DNA of tumor suppressor genes like SMARCB1 or SMARCA4 may lead to cancer.   Changes in the SMARCB1 or SMARCA4 genes may be inherited (passed on from parents to offspring). When this gene change is inherited, tumors may form in two parts of the body at the same time (for example, in the brain and the kidney). For patients with AT/RT, genetic counseling (a discussion with a trained professional about inherited diseases and a possible need for gene testing) may be recommended.
Source: CancerGov
Topic: Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor
Question: What are the symptoms of Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor ?
Answer: The signs and symptoms of atypical teratoid/rhabdoid tumor are not the same in every patient. Signs and symptoms depend on the following:         - The child's age.    - Where the tumor has formed.        Because atypical teratoid/rhabdoid tumor is fast growing, signs and symptoms may develop quickly and get worse over a period of days or weeks. Signs and symptoms may be caused by AT/RT or by other conditions. Check with your child's doctor if your child has any of the following:         - Morning headache or headache that goes away after vomiting.    -  Nausea and vomiting.    - Unusual sleepiness or change in activity level.    - Loss of balance, lack of coordination, or trouble walking.    - Increase in head size (in infants).
Source: CancerGov
Topic: Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor
Question: How to diagnose Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor ?
Answer: Tests that examine the brain and spinal cord are used to detect (find) CNS atypical teratoid/rhabdoid tumor. The following tests and procedures may be used:         -   Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patient's health habits and past illnesses and treatments will also be taken.    -   Neurological exam : A series of questions and tests to check the brain, spinal cord, and nerve function. The exam checks a persons mental status, coordination, and ability to walk normally, and how well the muscles, senses, and reflexes work. This may also be called a neuro exam or a neurologic exam.     -   MRI (magnetic resonance imaging): A procedure that uses a magnet, radio waves, and a computer to make a series of detailed pictures of areas inside the brain and spinal cord. This procedure is also called nuclear magnetic resonance imaging (NMRI).    -   Lumbar puncture : A procedure used to collect cerebrospinal fluid (CSF) from the spinal column. This is done by placing a needle between two bones in the spine and into the CSF around the spinal cord and removing a sample of fluid. The sample of CSF is checked under a microscope for signs of tumor cells. The sample may also be checked for the amounts of protein and glucose. A higher than normal amount of protein or lower than normal amount of glucose may be a sign of a tumor. This procedure is also called an LP or spinal tap.    -   SMARCB1 and SMARCA4 gene testing: A laboratory test in which a sample of blood or tissue is tested for the SMARCB1 and SMARCA4 genes.
                    Childhood atypical teratoid/rhabdoid tumor is diagnosed and may be removed in surgery. If doctors think there might be a brain tumor, a biopsy may be done to remove a sample of tissue. For tumors in the brain, the biopsy is done by removing part of the skull and using a needle to remove a sample of tissue. A pathologist views the tissue under a microscope to look for cancer cells. If cancer cells are found, the doctor may remove as much tumor as safely possible during the same surgery. The pathologist checks the cancer cells to find out the type of brain tumor. It is often difficult to completely remove AT/RT because of where the tumor is in the brain and because it may already have spread at the time of diagnosis.      The following test may be done on the sample of tissue that is removed:         -   Immunohistochemistry : A test that uses antibodies to check for certain antigens in a sample of tissue. The antibody is usually linked to a radioactive substance or a dye that causes the tissue to light up under a microscope. This test is used to tell the difference between AT/RT and other brain tumors.
Source: CancerGov
Topic: Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor
Question: What is the outlook for Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor ?
Answer: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - Whether there are certain inherited gene changes.    - The age of the child.    - The amount of tumor remaining after surgery.    - Whether the cancer has spread to other parts of the central nervous system (brain and spinal cord) or to the kidney at the time of diagnosis.
Source: CancerGov
Topic: Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor
Question: What are the stages of Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor ?
Answer: Key Points
                    - There is no standard staging system for central nervous system atypical teratoid/rhabdoid tumor.
                
                
                    There is no standard staging system for central nervous system atypical teratoid/rhabdoid tumor.
                    The extent or spread of cancer is usually described as stages. There is no standard staging system for central nervous system atypical teratoid/rhabdoid tumor.    For treatment, this tumor is grouped as newly diagnosed or recurrent. Treatment depends on the following:         - The age of the child.    - How much cancer remains after surgery to remove the tumor.        Results from the following procedure are also used to plan treatment:         -   Ultrasound exam: A procedure in which high-energy sound waves (ultrasound) are bounced off internal tissues or organs, such as the kidney, and make echoes. The echoes form a picture of body tissues called a sonogram. The picture can be printed to be looked at later. This procedure is done to check for tumors that may also have formed in the kidney.
Source: CancerGov
Topic: Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor
Question: what research (or clinical trials) is being done for Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor ?
Answer: New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Targeted therapy     Targeted therapy is a type of treatment that uses drugs or other substances to attack specific cancer cells. Targeted therapies usually cause less harm to normal cells than chemotherapy or radiation therapy do. Targeted therapy is being studied in the treatment of recurrent childhood central nervous system atypical teratoid/rhabdoid tumor.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
Source: CancerGov
Topic: Retinoblastoma
Question: What is (are) Retinoblastoma ?
Answer: Key Points
                    - Retinoblastoma is a disease in which malignant (cancer) cells form in the tissues of the retina.    - Retinoblastoma occurs in heritable and nonheritable forms.     -  Treatment for both forms of retinoblastoma should include genetic counseling.    - Children with a family history of retinoblastoma should have eye exams to check for retinoblastoma.     - A child who has heritable retinoblastoma has an increased risk of trilateral retinoblastoma and other cancers.    - Signs and symptoms of retinoblastoma include "white pupil" and eye pain or redness.     - Tests that examine the retina are used to detect (find) and diagnose retinoblastoma.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Retinoblastoma is a disease in which malignant (cancer) cells form in the tissues of the retina.
                    The retina is the nerve tissue that lines the inside of the back of the eye. The retina senses light and sends images to the brain by way of the optic nerve.      Although retinoblastoma may occur at any age, it occurs most often in children younger than 2 years. The cancer may be in one eye (unilateral) or in both eyes (bilateral). Retinoblastoma rarely spreads from the eye to nearby tissue or other parts of the body.    Cavitary retinoblastoma is a rare type of retinoblastoma in which cavities (hollow spaces) form within the tumor.
                
                
                    Treatment for both forms of retinoblastoma should include genetic counseling.
                    Parents should receive genetic counseling (a discussion with a trained professional about the risk of genetic diseases) to discuss genetic testing to check for a mutation (change) in the RB1 gene. Genetic counseling also includes a discussion of the risk of retinoblastoma for the child and the child's brothers or sisters.
Source: CancerGov