sarnsrun/medquad huggingface dataset:
Topic: Ovarian Germ Cell Tumors
Question: How to diagnose Ovarian Germ Cell Tumors ?
Answer: Tests that examine the ovaries, pelvic area, blood, and ovarian tissue are used to detect (find) and diagnose ovarian germ cell tumor. The following tests and procedures may be used:          -   Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patients health habits and past illnesses and treatments will also be taken.    -   Pelvic exam : An exam of the vagina, cervix, uterus, fallopian tubes, ovaries, and rectum. A speculum is inserted into the vagina and the doctor or nurse looks at the vagina and cervix for signs of disease. A Pap test of the cervix is usually done. The doctor or nurse also inserts one or two lubricated, gloved fingers of one hand into the vagina and places the other hand over the lower abdomen to feel the size, shape, and position of the uterus and ovaries. The doctor or nurse also inserts a lubricated, gloved finger into the rectum to feel for lumps or abnormal areas.    -   Laparotomy : A surgical procedure in which an incision (cut) is made in the wall of the abdomen to check the inside of the abdomen for signs of disease. The size of the incision depends on the reason the laparotomy is being done. Sometimes organs are removed or tissue samples are taken and checked under a microscope for signs of disease.    -   CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography.    -   Serum tumor marker test : A procedure in which a sample of blood is checked to measure the amounts of certain substances released into the blood by organs, tissues, or tumor cells in the body. Certain substances are linked to specific types of cancer when found in increased levels in the blood. These are called tumor markers. An increased level of alpha fetoprotein (AFP) or human chorionic gonadotropin (HCG) in the blood may be a sign of ovarian germ cell tumor.
Source: CancerGov
Topic: Ovarian Germ Cell Tumors
Question: What is the outlook for Ovarian Germ Cell Tumors ?
Answer: Certain factors affect prognosis (chance of recovery and treatment options). The prognosis (chance of recovery) and treatment options depend on the following:         - The type of cancer.    -  The size of the tumor.    - The stage of cancer (whether it affects part of the ovary, involves the whole ovary, or has spread to other places in the body).    - The way the cancer cells look under a microscope.    - The patients general health.         Ovarian germ cell tumors are usually cured if found and treated early.
Source: CancerGov
Topic: Ovarian Germ Cell Tumors
Question: what research (or clinical trials) is being done for Ovarian Germ Cell Tumors ?
Answer: New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     High-dose chemotherapy with bone marrow transplant     High-dose chemotherapy with bone marrow transplant is a method of giving very high doses of chemotherapy and replacing blood -forming cells destroyed by the cancer treatment. Stem cells (immature blood cells) are removed from the bone marrow of the patient or a donor and are frozen and stored. After the chemotherapy is completed, the stored stem cells are thawed and given back to the patient through an infusion. These reinfused stem cells grow into (and restore) the bodys blood cells.       New treatment options      Combination chemotherapy (the use of more than one anticancer drug) is being tested in clinical trials.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
Source: CancerGov
Topic: Neuroblastoma
Question: What is (are) Neuroblastoma ?
Answer: Key Points
                    - Neuroblastoma is a disease in which malignant (cancer) cells form in neuroblasts (immature nerve tissue) in the adrenal gland, neck, chest, or spinal cord.    - Neuroblastoma is sometimes caused by a gene mutation (change) passed from the parent to the child.    - Signs and symptoms of neuroblastoma include bone pain and a lump in the abdomen, neck, or chest.     - Tests that examine many different body tissues and fluids are used to detect (find) and diagnose neuroblastoma.    - A biopsy is done to diagnose neuroblastoma.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Neuroblastoma is a disease in which malignant (cancer) cells form in neuroblasts (immature nerve tissue) in the adrenal gland, neck, chest, or spinal cord.
                    Neuroblastoma often begins in the nerve tissue of the adrenal glands. There are two adrenal glands, one on top of each kidney in the back of the upper abdomen. The adrenal glands make important hormones that help control heart rate, blood pressure, blood sugar, and the way the body reacts to stress. Neuroblastoma may also begin in nerve tissue in the neck, chest, abdomen or pelvis.      Neuroblastoma most often begins in infancy and may be diagnosed in the first month of life. It is found when the tumor begins to grow and cause signs or symptoms. Sometimes it forms before birth and is found during a fetal ultrasound.   By the time neuroblastoma is diagnosed, the cancer has usually metastasized (spread). Neuroblastoma spreads most often to the lymph nodes, bones, bone marrow, and liver. In infants, it also spreads to the skin.
Source: CancerGov
Topic: Neuroblastoma
Question: Is Neuroblastoma inherited ?
Answer: Neuroblastoma is sometimes caused by a gene mutation (change) passed from the parent to the child. Gene mutations that increase the risk of neuroblastoma are sometimes inherited (passed from the parent to the child). In children with a gene mutation, neuroblastoma usually occurs at a younger age and more than one tumor may form in the adrenal glands.
Source: CancerGov
Topic: Neuroblastoma
Question: What are the symptoms of Neuroblastoma ?
Answer: Signs and symptoms of neuroblastoma include bone pain and a lump in the abdomen, neck, or chest.The most common signs and symptoms of neuroblastoma are caused by the tumor pressing on nearby tissues as it grows or by cancer spreading to the bone. These and other signs and symptoms may be caused by neuroblastoma or by other conditions.   Check with your childs doctor if your child has any of the following:         - Lump in the abdomen, neck, or chest.    - Bulging eyes.    - Dark circles around the eyes ("black eyes").    - Bone pain.    - Swollen stomach and trouble breathing (in infants).    - Painless, bluish lumps under the skin (in infants).    - Weakness or paralysis (loss of ability to move a body part).        Less common signs and symptoms of neuroblastoma include the following:         -  Fever.    - Shortness of breath.    - Feeling tired.    - Easy bruising or bleeding.    -  Petechiae (flat, pinpoint spots under the skin caused by bleeding).    -  High blood pressure.     - Severe watery diarrhea.    -  Horner syndrome (droopy eyelid, smaller pupil, and less sweating on one side of the face).    - Jerky muscle movements.    - Uncontrolled eye movements.
Source: CancerGov
Topic: Neuroblastoma
Question: What is the outlook for Neuroblastoma ?
Answer: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - Age of the child at the time of diagnosis.    - The child's risk group.    - Whether there are certain changes in the genes.    - Where in the body the tumor started.    - Tumor histology (the shape, function, and structure of the tumor cells).    - Whether there is cancer in the lymph nodes on the same side of the body as the primary cancer or whether there is cancer in the lymph nodes on the opposite side of the body.    - How the tumor responds to treatment.    - How much time passed between diagnosis and when the cancer recurred (for recurrent cancer).        Prognosis and treatment options for neuroblastoma are also affected by tumor biology, which includes:          - The patterns of the tumor cells.    - How different the tumor cells are from normal cells.    - How fast the tumor cells are growing.    - Whether the tumor shows MYCN amplification.    - Whether the tumor has changes in the ALK gene.         The tumor biology is said to be favorable or unfavorable, depending on these factors. A favorable tumor biology means there is a better chance of recovery.   In some children up to 6 months old, neuroblastoma may disappear without treatment. This is called spontaneous regression. The child is closely watched for signs or symptoms of neuroblastoma. If signs or symptoms occur, treatment may be needed.
Source: CancerGov
Topic: Neuroblastoma
Question: what research (or clinical trials) is being done for Neuroblastoma ?
Answer: New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Immunotherapy     Immunotherapy is a treatment that uses the patients immune system to fight cancer. Substances made by the body or made in a laboratory are used to boost, direct, or restore the bodys natural defenses against cancer. This type of cancer treatment is also called biotherapy or biological therapy.     Vaccine therapy uses a substance to stimulate the immune system to destroy a tumor. Vaccine therapy is being studied to treat neuroblastoma that has come back after treatment.       Other drug therapy     Lenalidomide is a type of angiogenesis inhibitor. It prevents the growth of new blood vessels that are needed by a tumor to grow.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
Source: CancerGov
Topic: Childhood Hodgkin Lymphoma
Question: Who is at risk for Childhood Hodgkin Lymphoma? ?
Answer: Epstein-Barr virus infection increases the risk of childhood Hodgkin lymphoma. Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk with your childs doctor if you think your child may be at risk.    Risk factors for childhood Hodgkin lymphoma include the following:          - Being infected with the Epstein-Barr virus.    - Being infected with the human immunodeficiency virus (HIV).    - Having certain diseases of the immune system.    - Having a personal history of mononucleosis ("mono").    - Having a parent or sibling with a personal history of Hodgkin lymphoma.        Being exposed to common infections in early childhood may decrease the risk of Hodgkin lymphoma in children because of the effect it has on the immune system.
Source: CancerGov
Topic: Childhood Hodgkin Lymphoma
Question: What are the symptoms of Childhood Hodgkin Lymphoma ?
Answer: Signs of childhood Hodgkin lymphoma include swollen lymph nodes, fever, night sweats, and weight loss. These and other signs and symptoms may be caused by childhood Hodgkin lymphoma or by other conditions. Check with your child's doctor if your child has any of the following:         - Painless, swollen lymph nodes near the collarbone or in the neck, chest, underarm, or groin.    -  Fever for no known reason.     - Weight loss for no known reason.    - Night sweats.    -  Fatigue.    -  Anorexia.    - Itchy skin.    - Pain in the lymph nodes after drinking alcohol.        Fever, weight loss, and night sweats are called B symptoms.
Source: CancerGov
Topic: Childhood Hodgkin Lymphoma
Question: What is the outlook for Childhood Hodgkin Lymphoma ?
Answer: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - The stage of the cancer.    - The size of the tumor.    -  Whether there are B symptoms at diagnosis.    - The type of Hodgkin lymphoma.    - Certain features of the cancer cells.    - Whether there are too many white blood cells or too few red blood cells at the time of diagnosis.    - How well the tumor responds to initial treatment with chemotherapy.    - Whether the cancer is newly diagnosed or has recurred (come back).         The treatment options also depend on:         - The child's age and gender.    - The risk of long-term side effects.        Most children and adolescents with newly diagnosed Hodgkin lymphoma can be cured.
Source: CancerGov
Topic: Childhood Hodgkin Lymphoma
Question: what research (or clinical trials) is being done for Childhood Hodgkin Lymphoma ?
Answer: New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Proton beam radiation therapy     Proton-beam therapy is a type of high-energy, external radiation therapy that uses streams of protons (small, positively-charged particles of matter) to make radiation. This type of radiation therapy may help lessen the damage to healthy tissue near the tumor.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials.
Source: CancerGov
Topic: Penile Cancer
Question: What is (are) Penile Cancer ?
Answer: Key Points
                    - Penile cancer is a disease in which malignant (cancer) cells form in the tissues of the penis.    - Human papillomavirus infection may increase the risk of developing penile cancer.    - Signs of penile cancer include sores, discharge, and bleeding.    - Tests that examine the penis are used to detect (find) and diagnose penile cancer.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Penile cancer is a disease in which malignant (cancer) cells form in the tissues of the penis.
                    The penis is a rod-shaped male reproductive organ that passes sperm and urine from the body. It contains two types of erectile tissue (spongy tissue with blood vessels that fill with blood to make an erection):          - Corpora cavernosa: The two columns of erectile tissue that form most of the penis.    -  Corpus spongiosum: The single column of erectile tissue that forms a small portion of the penis. The corpus spongiosum surrounds the urethra (the tube through which urine and sperm pass from the body).        The erectile tissue is wrapped in connective tissue and covered with skin. The glans (head of the penis) is covered with loose skin called the foreskin.
Source: CancerGov
Topic: Penile Cancer
Question: Who is at risk for Penile Cancer? ?
Answer: Human papillomavirus infection may increase the risk of developing penile cancer. Anything that increases your chance of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer. Talk with your doctor if you think you may be at risk. Risk factors for penile cancer include the following:    Circumcision may help prevent infection with the human papillomavirus (HPV). A circumcision is an operation in which the doctor removes part or all of the foreskin from the penis. Many boys are circumcised shortly after birth. Men who were not circumcised at birth may have a higher risk of developing penile cancer.    Other risk factors for penile cancer include the following:         - Being age 60 or older.    - Having phimosis (a condition in which the foreskin of the penis cannot be pulled back over the glans).    - Having poor personal hygiene.    - Having many sexual partners.    - Using tobacco products.
Source: CancerGov
Topic: Penile Cancer
Question: What are the symptoms of Penile Cancer ?
Answer: Signs of penile cancer include sores, discharge, and bleeding. These and other signs may be caused by penile cancer or by other conditions. Check with your doctor if you have any of the following:         - Redness, irritation, or a sore on the penis.    - A lump on the penis.
Source: CancerGov
Topic: Penile Cancer
Question: How to diagnose Penile Cancer ?
Answer: Tests that examine the penis are used to detect (find) and diagnose penile cancer. The following tests and procedures may be used:         -   Physical exam and history : An exam of the body to check general signs of health, including checking the penis for signs of disease, such as lumps or anything else that seems unusual. A history of the patients health habits and past illnesses and treatments will also be taken.    -   Biopsy : The removal of cells or tissues so they can be viewed under a microscope by a pathologist to check for signs of cancer. The tissue sample is removed during one of the following procedures:                -  Fine-needle aspiration (FNA) biopsy : The removal of tissue or fluid using a thin needle.      -  Incisional biopsy : The removal of part of a lump or a sample of tissue that doesn't look normal.      -  Excisional biopsy : The removal of an entire lump or area of tissue that doesnt look normal.
Source: CancerGov
Topic: Penile Cancer
Question: What is the outlook for Penile Cancer ?
Answer: Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - The stage of the cancer.    - The location and size of the tumor.    - Whether the cancer has just been diagnosed or has recurred (come back).
Source: CancerGov