<>Hismanal (astemizole) is most definitely linked to weight gain.
<>It really is peculiar that some antihistamines have this effect,
<>and even more so an antihistamine like astemizole which purportedly
<>doesn't cross the blood-brain barrier and so tends not to cause
<>drowsiness.
<
<The original poster mentioned fatigue.  I had that too, but it was
<mostly due to the really bizarre dreams I was having -- I wasn't getting
<any rest.  My doctor said that was a common reaction.  If astemizole
<doesn't cross the blood-brain barrier, how does it cause that side
<effect?  Any ideas?