Babak gugur Liga Champions AFC 2012

The matchups for the round of 16 were decided based on the results from the group stage. After the completion of the round of 16, the draw for the quarter-finals, semi-finals, and final was held at the AFC house in Kuala Lumpur, Malaysia on 14 June 2012, 16:00 . In this draw, the "country protection" rule is applied: if there are exactly two clubs from the same country, they may not face each other in the quarter-finals; however, if there are more than two clubs from the same country, they may face each other in the quarter-finals.