Spike TV Video Game Award

The 2006 "VGAs" featured musical performances by Tenacious D and AFI and show appearances by 50 Cent, Eva Mendes, Sarah Silverman, Seth Green, Masi Oka, Hayden Panettiere, Brandon Routh, Rachael Leigh Cook, Tony Hawk, Michael Irvin, Method Man, Maria Menounos, Tyrese, Xzibit, James Gandolfini, Kurt Angle, among others. In character as Stewie Griffin and Tom Tucker from Family Guy, Seth MacFarlane served as the voice of the VGAs. The awards aired December 13, 2006 and were hosted by Samuel L. Jackson.