Los Santos, San Andreas

Kota ini mirip dengan Los Angeles. Contohnya saja daerah Compton, Willowbrook, Watts, Inglewood, Hollywood, Beverly Hills, Santa Monica Beach, Venice Beach, Watts Towers, Los Angeles Convention Center, Capitol Tower, Los Angeles City Hall, U.S. Bank Tower, Griffith Observatory, Santa Monica Pier, Vincent Thomas Bridge, Rodeo Drive, Hollywood Walk Of Fame, Westin Bonaventure Hotel, Grauman's Chinese Theater, dan East Los Angeles di Los Angeles. Ada beberapa ikon kota terkenal di Los Santos, seperti, Vinewood, Rockford Hills, Santa Maria Beach, Verona Beach, Maze Bank Tower, Maze Bank Arena, Vinewood Signs, Idlewood, dll.