rpgv/AptaCom huggingface dataset:
Aptamer: Vaspin binding aptamer (VBA) (ID# 7774)
Aptamer chemistry: DNA
Aptamer sequence: ATACCAGCTTATTCAATTGGGCGGTGGGGGGGGTAGTGGGTGTTATGGCGATCGTGGAGATAGTAAGTGCAATCT
Target: Vaspin
Target chemistry: Protein
Affinity: 303 nM 
Reference: SJ Lee et al. Sensitive detection of adipokines for early diagnosis of type 2 diabetes using enzyme-linked antibody-aptamer sandwich (ELAAS) assays. Sensors Actuat. B-Chem.(2012): 243-248.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: 2′-O-Methyl modified RNA aptamer (ID# 7874)
Aptamer chemistry: 2'-O-Me-RNA
Aptamer sequence: GGGCGAAUUCGGGUUGGAUAGUAGGCGCAUAUGGCAUCUUCGUGGUUGUGUAUUGCCCUUUAGUGAGGGUUAAUU
Target: p53
Target chemistry: Protein
Affinity: Not Mentioned in Database
Reference: Shwetha, N. et al. "Aptamerƒ??nanoparticle-based chemiluminescence for p53 protein." Analytical Biochemistry 2013, 441: 73-79.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: G5a3N.4 (ID# 7910)
Aptamer chemistry: DNA
Aptamer sequence: TAATACGACTCACTATAGGGAGACCCAAGCCGATTTATTTTGTGCAGCTTTTGTTCCCTTTAGTGAGGGTTAATT
Target: HPV-16E7 protein
Target chemistry: Protein
Affinity: 1.9 µM 
Reference: Julia D. Toscano-Garibay, Maria L. Benitez-Hess, and Luis M. Alvarez-Salas. 2011. Isolation and Characterization of an RNA Aptamer for the HPV-16 E7 Oncoprotein. Archives of Medical Research 42 (2011) 88-96Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: SARS-CoV-2 RBD-4C (ID# 8008)
Aptamer chemistry: DNA
Aptamer sequence: ATCCAGAGTGACGCAGCATTTCATCGGGTCCAAAAGGGGCTGCTCGGGATTGCGGATATGGACACGT
Target: SARS CoV-2
Target chemistry: Other
Affinity: 19.9 nM 
Reference: Discovery of Aptamers Targeting Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein (2020)Yanling Song,*a Jia Song,b Xinyu Wei,a Mengjiao Huang,a Miao Sun,a Lin Zhu,a Bingqian Lin,a Haicong Shen,a Zhi Zhu,a Chaoyong Yang *a,b  *a. The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China  *b. Institute of Molecular Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, ChinaMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: H6 (ID# 8140)
Aptamer chemistry: DNA
Aptamer sequence: ATACGAGCTTGTTCAATAGTCTGAAGGGATTGAGTATCCGGGGAGATGATGTCGTTGGTGATAGTAAGAGCAATC
Target: Triclosan
Target chemistry: Protein
Affinity: 369.82 nM 
Reference: Li S, Clarkson M, McNatty K. Selection and characterisation of triclosan-specific aptamers using a fluorescence microscope-imaging assay. Anal Bioanal Chem. 2020 Oct;412(26):7285-7294. doi: 10.1007/s00216-020-02863-7. Epub 2020 Aug 11. PMID: 32780154.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Anti HA Influenza Virus Clone B (ID# 8181)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGAAUUCCGACCAGAAGGGUUAGCGGUCGUCUUAAGGUAGUUUUUGGUCCUUUCCUCUCUCCUUCCUCUUCU
Target: human infuenza virus hemagglutinin
Target chemistry: Protein
Affinity: 115 pM 
Reference: Misono, T. S., and P. K. R. Kumar. (2005). Selection of RNA aptamers against human influenza virus hemagglutinin using surface plasmon resonance. Analytical Biochemistry, 342(2), 312–317. doi:10.1016/j.ab.2005.04.013Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: T3 (ID# 8186)
Aptamer chemistry: DNA
Aptamer sequence: CGCTCGGATCGATAAGCTTCGAGCCTGAGTTTTTGCCGCGATCTCGACCTCCGTCACGGATCCTCTAGAGCACTG
Target: Ovarian cancer tumor cells
Target chemistry: Tissue
Affinity: Not Mentioned in Database
Reference: Wang, Hongyu et al. “Morph-X-Select: Morphology-based tissue aptamer selection for ovarian cancer biomarker discovery.” BioTechniques vol. 61,5 249-259. 1 Nov. 2016, doi:10.2144/000114473Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: mHtt2.2.47 (ID# 8221)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGAGAGAGACAGUCUGCCCCGAUUAAAAUAGCACAGCAACCAACGCCCCCCCAAGCAACGUCAACUCCAGAA
Target: 51Q-htt
Target chemistry: Protein
Affinity: 388.3 nM 
Reference: Rajeev K Chaudhary, Kinjal A Patel, Milan K Patel, Radha H Joshi, Ipsita Roy, Inhibition of Aggregation of Mutant Huntingtin by Nucleic Acid Aptamers In Vitro and in a Yeast Model of Huntington's Disease, Molecular Therapy, Volume 23, Issue 12, 2015, Pages 1912-1926, ISSN 1525-0016.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: AP273 (Alpha-fetoprotein) (ID# 8229)
Aptamer chemistry: DNA
Aptamer sequence: GTGACGCTCCTAACGCTGACTCAGGTGCAGTTCTCGACTCGGTCTTGATGTGGGTCCTGTCCGTCCGAACCAATC
Target: Alpha Fetoprotein (AFP)
Target chemistry: Protein
Affinity: 17.4 nM 
Reference: Screening and Identifying a Novel ssDNA Aptamer against Alpha-fetoprotein Using CE-SELEXLili. Dong, et. al. (2015)https://www.nature.com/articles/srep15552Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: von Willebrand Factor (VWF R9.3) (ID# 7579)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGGAGGACGAUGCGGAUCGCGCUCUCCUGCUUAAGCAGCUAUCAAAUAGCCCACUCAGACGACUCGCUGAGGAUCC
Target: von Willebrand Factor (VWF)
Target chemistry: Protein
Affinity: 1.2 nM 
Reference: S Oney, BA Sullenger, et al. (2007) "Antidote-Controlled Platelet Inhibition Targeting von Willebrand Factor with Aptamers." Oligonucleotides, 17:265-274.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Human Wild-type PAI-1 (WT-15) (ID# 7619)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGGAGGACGAUGCGGAUCAACUCACCGUAGGUCUAGUGAGAACUUCAAGUCUACUCAGACGACUCGCUGAGGAUCC
Target: Human Wild-type PAI-1
Target chemistry: Protein
Affinity: 177 pM 
Reference: Blake et al. "Antimetastatic Potential of PAI-1-Specific RNA Aptamers." Oligonucleotides, 19(2009): 117-128.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: theophylline-induced molecular switch (ID# 7762)
Aptamer chemistry: RNA
Aptamer sequence: GGGCGACCCUGAUGAGCCUUAUACCAGCCGAAAGGCCCUUGGCAGACGUCGAAACGGUGAAAGCCGUAGGUUGCCC
Target: theophylline
Target chemistry: Small Organic
Affinity: na nM 
Reference: Garrett A. Soukup and Ronald R. Breaker. "Engineering precision RNA molecular switches" Proc. Natl. Acad. Sci. 96(1999):3584-3589.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: RBP4 binding aptamer (RBA) (ID# 7773)
Aptamer chemistry: DNA
Aptamer sequence: ATACCAGCTTATTCAATTACAGTAGTGAGGGGTCCGTCGTGGGGTAGTTGGGTCGTGGAGATAGTAAGTGCAATCT
Target: Retinol-binding protein-4 (RBP4)
Target chemistry: Protein
Affinity: 201 nM 
Reference: SJ Lee et al. Sensitive detection of adipokines for early diagnosis of type 2 diabetes using enzyme-linked antibody-aptamer sandwich (ELAAS) assays. Sensors Actuat. B-Chem.(2012): 243-248.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Nampt binding aptamer (NBA) (ID# 7775)
Aptamer chemistry: DNA
Aptamer sequence: ATACCAGCTTATTCAATTGGGCAGGACAGGTGTCGGCTTGATAGGCTGGGGTGTGTGTAGATAGTAAGTGCAATCT
Target: Nampt/Nicotinamide phosphoribosyltransferase
Target chemistry: Protein
Affinity: 72.52 nM 
Reference: Park, J.-W., Tatavarty, R., Kim, D. W., Jung, H.-T., & Gu, M. B. (2012). Immobilization-free screening of aptamers assisted by graphene oxide. Chem. Commun., 48(15), 2071–2073. doi:10.1039/c2cc16473fSJ Lee et al. Sensitive detection of adipokines for early diagnosis of type 2 diabetes using enzyme-linked antibody-aptamer sandwich (ELAAS) assays. Sensors Actuat. B-Chem.(2012): 243-248.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: von Willebrand Factor (VWF R9.14) (ID# 7846)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGGAGGACGAUGCGGUGGACGAACUGCCCUCAGCUACUUUCAUGUUGCUGACGCACAGACGACUCGCUGAGGAUCC
Target: von Willebrand Factor (VWF)
Target chemistry: Protein
Affinity: 12 nM 
Reference: S Oney, BA Sullenger, et al. (2007) "Antidote-Controlled Platelet Inhibition Targeting von Willebrand Factor with Aptamers." Oligonucleotides, 17:265-274.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: U2 (ID# 7882)
Aptamer chemistry: DNA
Aptamer sequence: ATCCAGAGTGACGCAGCATTTTGACGCTTTATCCTTTTCTTATGGCGGGATAGTTTCGTGGACACGGTGGCTTAGT
Target: U87-EGFRvIII
Target chemistry: Cells
Affinity: 3.37 nM 
Reference: Wu, X. et al. "Cell-SELEX Aptamer for Highly Specific Radionuclide Molecular Imaging of Glioblastoma In Vivo." PLOS One 2014, 9:3.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: U8 (ID# 7883)
Aptamer chemistry: DNA
Aptamer sequence: ATCCAGAGTGACGCAGCATGAATCTTTTCTTTTGGTTTTGATATTTATAGTTGGTGAATGGACACGGTGGCTTAGT
Target: U87-EGFRvIII
Target chemistry: Cells
Affinity: 4.35 nM 
Reference: "Cell-SELEX Aptamer for Highly Specific Radionuclide Molecular Imaging of Glioblastoma In Vivo." PLOS One 2014, 9:3.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: U19 (ID# 7884)
Aptamer chemistry: DNA
Aptamer sequence: ATCCAGAGTGACGCAGCATTTGTATCCTATTTTGTTTATGTAATTGTCGTTGATCATGTGGACACGGTGGCTTAGT
Target: U87-EGFRvIII
Target chemistry: Cells
Affinity: 16.7 nM 
Reference: Wu, X. et al. "Cell-SELEX Aptamer for Highly Specific Radionuclide Molecular Imaging of Glioblastoma In Vivo." PLOS One 2014, 9:3.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: U31 (ID# 7885)
Aptamer chemistry: DNA
Aptamer sequence: ATCCAGAGTGACGCAGCATTTGTTTAATATGTTTTTTAATTCCCCTTGTGGTGTGTTGTGGACACGGTGGCTTAGT
Target: U87-EGFRvIII
Target chemistry: Cells
Affinity: 8.1 nM 
Reference: Wu, X. et al. "Cell-SELEX Aptamer for Highly Specific Radionuclide Molecular Imaging of Glioblastoma In Vivo." PLOS One 2014, 9:3.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Oxytetracycline binding aptamer (OTC-4) (ID# 8002)
Aptamer chemistry: DNA
Aptamer sequence: CGTACGGAATTCGCTAGCCGACGCGCGTTGGTGGTGGATGGTGTGTTACACGTGTTGTGGATCCGAGCTCCACGTG
Target: Oxytetracycline
Target chemistry: Small Organic
Affinity: 9.61 nM 
Reference: Niazi, J. H., Lee, S. J., Kim, Y. S., & Gu, M. B. (2008). ssDNA aptamers that selectively bind oxytetracycline. Bioorganic & Medicinal Chemistry, 16(3), 1254–1261. doi:10.1016/j.bmc.2007.10.073Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Diversely Functionalized Human alpha-Thrombin Aptamer (ID# 8028)
Aptamer chemistry: DNA
Aptamer sequence: GGATCCGAGCTCCACGTGACTGCATCTAATTCCAACCTATCCAATCCTATTCGATGCTTGCGACGGCAGGCGAATC
Target: Human alpha-Thrombin
Target chemistry: Protein
Affinity: 1.6 nM 
Reference: DOI: 10.1021/jacs.7b07241J. Am. Chem. Soc. 2017, 139, 13977−13980Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: SQ-2 (ID# 8066)
Aptamer chemistry: RNA
Aptamer sequence: AUACCAGCUUAUUCAAUUGCCUGAAAAGCUAUCGCCCAAUUCGCAGUGAUAUCCUUUAAGAUAGUAAGUGCAAUCU
Target: ALPPL-2
Target chemistry: Protein
Affinity: 22.25-24.74 nM 
Reference: Dua, P., Kang, H. S., Hong, S.-M., Tsao, M.-S., Kim, S., & Lee, D. -k. (2013). Alkaline Phosphatase ALPPL-2 Is a Novel Pancreatic Carcinoma-Associated Protein. Cancer Research, 73(6), 1934–1945. doi:10.1158/0008-5472.can-12-3682Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: NC23 (ID# 8075)
Aptamer chemistry: DNA
Aptamer sequence: ATACCAGCTTATTCAATTAGACGAGTTTTATTCATTTTCCATGTCGTAGCTTACCGTGAGATAGTAAGTGCAATCT
Target: N‑Cadherin Protein
Target chemistry: Protein
Affinity: 174 nM 
Reference: Yang, L., Gao, T., Li, W., Luo, Y., Ullah, S., Fang, X., … Pei, R. (2020). Ni-Nitrilotriacetic Acid Affinity SELEX Method for Selection of DNA Aptamers Specific to the N-Cadherin Protein. ACS Combinatorial Science. doi:10.1021/acscombsci.0c00165 Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Aptamer-6 (ID# 8170)
Aptamer chemistry: DNA
Aptamer sequence: ATCTAGAGTGACGCAGCAGGGCTTGGGTTGGGAATAAAGATGTGGGAGGCGGCGAACATGGACACGGTGGCTTAGT
Target: S/RBD receptor binding
Target chemistry: Protein
Affinity: 27.6 nM 
Reference: https://doi.org/10.1002/anie.202100345Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: SE43 (ID# 8191)
Aptamer chemistry: DNA
Aptamer sequence: TACGACTCACTATAGGGATCCGTGACTGTACGGGCTCAGTCGTTACTTGAGAGTTGAATTCCCTTTAGTGAGGGTT
Target: Staphylococcus epidermidis
Target chemistry: Cells
Affinity: Not Mentioned in Database
Reference: Kaur SJ, Gilman V, Duong M, Asher DM, Gregori L. Rapid selection of single-stranded DNA aptamers binding Staphylococcus epidermidis in platelet concentrates. Biotechniques. 2018 Dec;65(6):331-338. doi: 10.2144/btn-2018-0081. PMID: 30477331.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: T20 (ID# 8233)
Aptamer chemistry: DNA
Aptamer sequence: CGTACGGAATTCGCTAGCCCCCCGGCAGGCCACGGCTTGGGTTGGTCCCACTGCGCGTGGATCCGAGCTCCACGTG
Target: Tetracycline
Target chemistry: Small Organic
Affinity: 63.6 nM 
Reference: Niazi, J. H., Lee, S. J., & Gu, M. B. (2008). Single-stranded DNA aptamers specific for antibiotics tetracyclines. Bioorganic & medicinal chemistry, 16(15), 7245–7253. https://doi.org/10.1016/j.bmc.2008.06.033https://pubmed.ncbi.nlm.nih.gov/18617415/Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: apHAT610 (ID# 8238)
Aptamer chemistry: DNA
Aptamer sequence: GTTGCTCGTATTTAGGGCGGGGGGGCGGGGGAGGAGGTGGCGGGAATATCCATTGTCTACACCAGTCTTCATCCGC
Target: Histone acetyltransferase 1 (HAT1)
Target chemistry: Protein
Affinity: 28.11 nM 
Reference: Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: HIV-1 Integrase (P5) (ID# 7534)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGCUCAGAAUAAACGCUCAACCAGUCUUGUGGCUUUGAAAGAGAGGAGUGUUCGACAUGAGGCCCGGAUCCGGC
Target: HIV-1 Integrase
Target chemistry: Protein
Affinity: 10 nM 
Reference: Allen, P., et al. "Isolation of High-Affinity RNA Ligands to HIV-1 Integrase from a Random Pool." Virology, 209(1995): 327-336.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Rev Peptide (ID# 7649)
Aptamer chemistry: RNA
Aptamer sequence: GGACCUCGGCGAAAGCCGGUAACGCCACAAGUCGGAGGGUAAGAUCUGACAGGAACUGGGUGACGGAGGUUAGGUGC
Target: Rev Peptide
Target chemistry: Peptide
Affinity: 18 µM 
Reference: Hesselberth et al. "Simultaneous detection of diverse analytes with  an aptazyme ligase array." Analytical Biochemistry, 312(2003): 106-112.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: HIV-1 R5 SU Glycoprotein gp120 (B40t77) (ID# 7732)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGGAGACAAGACUAGACGCUCAAUGUGGGCCACGCCCGAUUUUACGCUUUUACCCGCACGCGAUUGGUUUGUUUCCC
Target: HIV-1 R5  gp120
Target chemistry: Protein
Affinity: 31 nM 
Reference: A. K. Dey et. al. Structural characterization of an anti-gp120 RNA aptamer that neutralizes R5 strains of HIV-1. RNA 11:873-884Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: HIV-1 Rev Peptide (L1-Rev) (ID# 7778)
Aptamer chemistry: RNA
Aptamer sequence: GGACCUCGGCGAAAGCCGGUAACGCCACAAGUCGGAGGGUAAGAUCUGACAGGAACUGGGUGACGGAGGUUAGGUGC
Target: HIV-1 Rev Peptide
Target chemistry: Peptide
Affinity: 18 µM 
Reference: Hesslberth et al. "Simultaneous Detection of Diverse Analytes with an Aptazyme Ligase Array." Analytical Biochemistry, 312, (2003):106-112.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: G1 (ID# 8087)
Aptamer chemistry: DNA
Aptamer sequence: ATACGACTCACTATTAGGGACAAAGCTGACAACCCTTTCATAATCTAACTACATTTATGTGCTAGACTACTGACTAC
Target: Glutathione S-transferase (GST)
Target chemistry: Protein
Affinity: 59 nM 
Reference: Wang Y, Li Z, Yu H. Aptamer-Based Western Blot for Selective Protein Recognition. Front Chem. 2020 Oct 29;8:570528. doi: 10.3389/fchem.2020.570528. PMID: 33195056; PMCID: PMC7658645.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: IgE (4.4.12) (ID# 7467)
Aptamer chemistry: DNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGTGAAACATAGCATATTTACTTATGTCGCCTTGCCGGTTCCTATGCGTGCTACCGTGAA
Target: IgE
Target chemistry: Protein
Affinity: 23 nM 
Reference: Mendonsa, Shaun D. and Bowser, Michael T. "In Vitro Selection of High-Affinity DNA Ligands for Human IgE Using Capillary Electrophoresis." Analytical Chemistry, 76 (2004): 5387-5392.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: TTF1 (A) (ID# 7468)
Aptamer chemistry: DNA
Aptamer sequence: GGTATTGAGGGTCGCATCTCAAAAGGGGTGATTGCTTGCACAATGACAGGGTAGGACAGATGGCTCTAACTCTCCTCT
Target: Thyroid Transcription Factor 1
Target chemistry: Protein
Affinity: 3.36 nM 
Reference: Murphy et al. "An improved method for the in vitro evolution of aptamers and applications in protein detection and purification." Nucleic Acids Research, 31 (2003): e110.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Taq DNA polymerase (TQ21) (ID# 7486)
Aptamer chemistry: DNA
Aptamer sequence: TTCTCGGTTGGTCTCTGGCGGAGCGATCATCTCAGAGCATTCTTAGCGTTTTGTTCTTGTGTATGATTCGCTTTTCCC
Target: Taq DNA polymerase
Target chemistry: Protein
Affinity: 36 pM 
Reference: Sumedha and Dang. "Oligonucleotide inhibitors of Taq DNA polymerase facilitate detection of low copy number targets by PCR." Journal of Molecular Biology, 264 (1996): 268-78.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Lactobacillum acidophilius (hemag1P) (ID# 7607)
Aptamer chemistry: DNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGTAGCCCTTCAACATAGTAATATCTCTGCATTCTGTGTGCCTATGCGTGCTACCGTGAA
Target: Lactobacillum acidophilius
Target chemistry: Cells
Affinity: 13 nM 
Reference: Hamula et al. "Selection of Aptamers against Live Bacterial Cells." Analytical Chemistry, 80(2008): 7812-7819.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Enterotoxin B (APT SEB1) (ID# 7685)
Aptamer chemistry: DNA
Aptamer sequence: GGTATTGAGGGTCGCATCCACTGGTCGTTGTTGTCTGTTGTCTGTTATGTTGTTTCGTGATGGCTCTAACTCTCCTCT
Target: Staphylococcus aureus Enterotoxin B
Target chemistry: Protein
Affinity: Not Mentioned in Database
Reference: DeGrasse, J. (2012). A single-stranded DNA aptamer that selectively binds to Staphylococcus aureus enterotoxin b. PloS One, 7(3): e33410. doi: 10.1371/journal.pone.0033410Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Terminal 8-oxodG DNA Lesion (R10-B35) (ID# 7852)
Aptamer chemistry: RNA
Aptamer sequence: GGGCGAAUUCCCGAGGACCAAAUAGUACCACCCGGGAAAACAGCUAAUGCCGAAACGGAGAUUUUUUCUGCAGAAGCU
Target: DNA Lesion 7,8-dihydro-8-hydroxy-2'-deoxyguanosine (8-oxodG)
Target chemistry: Small Organic
Affinity: 5 µM 
Reference: Rink, S. M. et al. "Creation of RNA molecules that recognize the oxidative lesion 7,8-dihydro-8-hydroxy-2*-deoxyguanosine (8-oxodG) in DNA." Proc. Natl. Acad. Sci., 95 (1998):11619-11624.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: JH6 (ID# 7875)
Aptamer chemistry: DNA
Aptamer sequence: GACGCTTACTCAGGTGTGACTCGGTACGCCGCAAGACGAGTTGTGTATAAGCCGGCCGAAGGACGCAGATGAAGTCTC
Target: NB4 AML cell line
Target chemistry: Cells
Affinity: 2.77 nM 
Reference: Yang, M. et al. "Developing aptamer probes for acute myelogenous leukemia detection and surface protein biomarker discovery." Journal of Hematology & Oncology 2014, 7:5.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: ACG03 (ID# 7892)
Aptamer chemistry: DNA
Aptamer sequence: ACGCTCGGATGCCACTACAGGGGGGTGGTCCTGAGGGTGGTGTGGTTGGTTTGGTTTCCTCATGGACGTGCTGGTGAC
Target: gastric cancer cell-line HGC-27
Target chemistry: Cells
Affinity: 16.49 nM 
Reference: Zhang, X. et al.  "A cell-based single-stranded DNA aptamer specifically targets gastric cancer."  The International Journal of Biochemistry & Cell Biology 2014, 46: 1-8.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: ATP C20 (ID# 7926)
Aptamer chemistry: RNA
Aptamer sequence: GGUUGGCAGCAGAAGAUAGCAGCCUGUCGUUCGCUUCUUGUCCGACUCCCCAUUCGCAGUCGAAGUGGUAACUAUCUUUAAGGGUCGGUCAAGGGAGGGAUCCUA
Target: ATP
Target chemistry: Small Organic
Affinity: 39 µM 
Reference: Weill L., Louis D., and Sargueil B., 2004.Selection and Evolution of NTP-Specific Aptamers. Nucleic Acids Research, 2004 Vol. 32 No. 17, 5045-5058Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: 2F11-14 (ID# 7935)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGACAAGAAUAAACGCUCAACGUUCAGUAUAACAGUCCGAGUCUAACACACAAUGGGACACUGAAUUCGACAGGAGGCUCACAACAGGC
Target: Ebola virus inhibitory domain (eVP35 IID) (EBOV) (eVP35)
Target chemistry: Protein
Affinity: 7.1 nM 
Reference: Jennifer M. Binning, Tianjiao Wang, Priya Luthra, Reed S. Shabman, Dominika M. Borek, Gai  Liu, Wei Xu, Daisy W. Leung, Christopher F. Basler, and Gaya K. Amarasinghe, ƒ??Development of RNA aptamers targeting ebolavirus VP35ƒ? Biochemistry 2013, 52, 8406-8419.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.