rpgv/AptaCom huggingface dataset:
Aptamer: Methylenedianiline (M1) (ID# 7496)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGACAAGAAUAAACGCUCAACUGCGAUCAGGGGUAAAUUUCCGCGCAGGCUCCACGCCGCUUCGACAGGAGGCUCACAACAGGC
Target: Methylenedianiline
Target chemistry: Small Organic
Affinity: 450 nM 
Reference: Brockstedt, U., et al. "In vitro evolution of RNA aptamers recognizing carcinogenic aromatic amines." Biochemical and Biophysical Research Communications, 313 (2004): 1004-1008.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: CD4 (Aptamer 7) (ID# 7526)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGGAGACAAGAAUAAACGCUCAAUGUGUCGUCCUGGUACGAUUUUGGUAUAUAACCGUGGCUUUUCGACAGGAGGCUCACAACAGGC
Target: CD4
Target chemistry: Protein
Affinity: 0.5 nM 
Reference: Davis, K., et al. "Staining of cell surface human CD4 with 2'-F-pyrimidine-containing RNA aptamers for flow cytometry." Nucleic Acids Research, 26(1998): 3915-3924.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Rous Sarcoma Virus (A) (ID# 7569)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGGAGCUCAGAAUAAACGCUCAAGGGUAGGGAUCGUUACCCCGACAUUUUAAUGGGCCGAUGUUUCGACAUGAGGCCCGGAUCCGGC
Target: Rous Sarcoma Virus
Target chemistry: Cells
Affinity: 20 nM 
Reference: Pan et al. Isolation of virus-neutralizing RNAs from a large pool of random sequences." PNAS, 92(1995): 11509-11513.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: V. parahemolyticus (A3P) (ID# 7671)
Aptamer chemistry: DNA
Aptamer sequence: ATAGGAGTCACGACGACCAGAATCTAAAAATGGGCAAAGAAACAGTGACTCGTTGAGATACTTATGTGCGTCTACCTCTTGACTAAT
Target: Vibrio parahemolyticus
Target chemistry: Cells
Affinity: 16.88 nM 
Reference: Duan, N et al. Selection and identification of a DNA aptamer targeted to Vibrio parahemolyticus. J. Agri. Food Chem., 60(2012): 4034-4038.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: HPV-HF cell line (20) (ID# 7701)
Aptamer chemistry: DNA
Aptamer sequence: ATACCAGCTTATTCAATTGGGGAGGGAGACACAGTCATGGAGCAGTTATTAGGGTGTACCGGGTGTAGTAGATAGTAAGTGCAATCT
Target: nontumorigenic HF cell line
Target chemistry: Cells
Affinity: 1.6 nM 
Reference: Graham JC, Zarbl H (2012) Use of Cell-SELEX to Generate DNA Aptamers as Molecular Probes of HPV-Associated Cervical Cancer Cells. PLoS ONE 7(4):  e36103. doi:10.1371/journal.pone.0036103Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Adipose Tissue (adipo-8) (ID# 7708)
Aptamer chemistry: DNA
Aptamer sequence: ATGAGAAGCGTCGGTGTGGTTAAACACGGAACGAAGGTGCAGGAAGATTTGTCGATGCGGTGCCTGAGCGGGCTGGCAAGGCGCATA
Target: Mature 3T3-L1 adipocytes (adipose tissue)
Target chemistry: Cells
Affinity: 17.8 nM 
Reference: J. Liu et. al. "Selection of aptamers specific for adipose tissue." PLoS One, 7(2012): e37789.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Anti Anterior Gradient Homolog 2 (ID# 7872)
Aptamer chemistry: DNA
Aptamer sequence: TCTCGGACGCGTGTGGTCGGGTGGGAGTTGTGGGGGGGGGTGGGAGGGTTCTTTGTTTGATCTTTCTCGCTGCCTGGCCCTAGAGTG
Target: Anterior Gradient Homolog 2 (AGR2)
Target chemistry: Protein
Affinity: 13.16 nM 
Reference: Wu et al. Identification, Characterization and Application of a G-Quadruplex  Structured DNA Aptamer against Cancer  Biomarker Protein Anterior Gradient Homolog 2 (PLOSone)Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: CTBA4 (ID# 8059)
Aptamer chemistry: DNA
Aptamer sequence: ATCTCGACTAGTCATAGGGGGCGCGAACATACGCGGTTGGTGTGGTTGGCTGACAATACTCGTTTTTGGTGTCTCGGAT
Target: Thrombin
Target chemistry: Protein
Affinity: 0.15 nM 
Reference: Yu Mao, Jimmy Gu, Dingran Chang, Lei Wang, Lili Yao, Qihui Ma, Zhaofeng Luo, Hao Qu, Yingfu Li, Lei Zheng, Evolution of a highly functional circular DNA aptamer in serum, Nucleic Acids Research, Volume 48, Issue 19, 4 November 2020, Pages 10680–10690Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: VRF-CSRB-01 (ID# 8234)
Aptamer chemistry: DNA
Aptamer sequence: TAGGGAAGAGAAGGACATATGATTCAAAGTAACTCTGTCACAGTACAATAGATTCTCATTATCATTGACTAGTACATGACCACTTGA
Target: Retinoblastoma (RB) (Weri-RB1 cells)
Target chemistry: Protein
Affinity: 49.41\u2009±\u20097.87 nM 
Reference: Maradani, B.S., Parameswaran, S. & Subramanian, K. Development and characterization of DNA aptamer against Retinoblastoma by Cell-SELEX. Sci Rep 12, 16178 (2022). https://doi.org/10.1038/s41598-022-20660-3https://www.nature.com/articles/s41598-022-20660-3#citeasMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: CCRF-CEM (sgc8) (ID# 7479)
Aptamer chemistry: DNA
Aptamer sequence: ATACCAGCTTATTCAATTAGTCACACTTAGAGTTCTAACTGCTGCGCCGCCGGGAAAATACTGTACGGTTAGATAGTAAGTGCAATCT
Target: Acute lymphoblastic leukemia (CCRF-CEM)
Target chemistry: Cells
Affinity: 0.8 nM 
Reference: Shangguan et al. ƒ??Aptamers evolved from live cells as effective molecular probes for cancer study.ƒ? Proceedings of the National Academy of Sciences of the United States of America, 103 (2006): 11838-43.    Sequence was given in:   Shangguan et al. "Optimization and Modifications of Aptamers Selected from Live Cancer Cell Lines." Chem. Biochem., 8, (2007): 603-6.   Target protein identification:  D Shangguan et al. Cell-specific aptamer probes for membrane protein elucidation in cancer cells. J. Proteome Res. 7:2133-2139.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Staphylococcus aureus (SA23) (ID# 7562)
Aptamer chemistry: DNA
Aptamer sequence: GCAATGGTACGGTACTTCCGGGCTGGCCAGATCAGACCCCGGATGATCATCCTTGTGAGAACCACAAAAGTGCACGCTACTTTGCTAA
Target: Staphylococcus aureus
Target chemistry: Cells
Affinity: 61.5 nM 
Reference: Cao et al. "Combining use of a panel of ssDNA aptamers in the detection of Staphylococcus aureus." Nucleic Acids Research, 37(2009): 1-8Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Flavin Mononucleotide (AR5) (ID# 7599)
Aptamer chemistry: RNA
Aptamer sequence: GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCUUAGGAUAUGCAUGAUGCAGAAGGACGUCGAAACGGUAGCGAGAGCUC
Target: FMN
Target chemistry: Small Organic
Affinity: Not Mentioned in Database
Reference: Seetharaman et al. "Immobilized RNA switches for the analysis of complex chemical and biological mixtures." Nature Biotechnology, 19(2001): 336-341.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Signal Recognition Particle 19 (SRP19) (ID# 7817)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGACAAGAAUAAACGCUCAACACAGAACGCGGUCCCCACACAGGACAGGAGCCAGCCCCGGUUCGACAGGAGGCUCACAACAGGC
Target: Signal Recognition Particle 19 (SRP19)
Target chemistry: Protein
Affinity: 0.6 nM 
Reference: Haraguchi, Y. Et al. Characterization of RNA aptamers against SRP19 protein having sequences different from SRP RNA.  Nucleic Acids Symposium Series, 2009, 53, 265-266.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Anti Influenza NS1 protein (ID# 7868)
Aptamer chemistry: DNA
Aptamer sequence: GCAATGGTACGGTACTTCCGCGGTCCGGGGTGGGTGGGTGGTGGGGGGTGCGGGGGGGCGGCCGCAAAAGTGCACGCTACTTTGCTAA
Target: NS1
Target chemistry: Protein
Affinity: 19.91 nM 
Reference: Hye-Min Woo. Single-stranded DNA aptamer that specifically binds to the influenza  Virus NS1 protein suppresses interferon antagonismMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Anti  Staphylococcus aureus (SA20) (ID# 7869)
Aptamer chemistry: DNA
Aptamer sequence: GCAATGGTACGGTACTTCCGCGCCCTCTCACGTGGCACTCAGAGTGCCGGAAGTTCTGCGTTATCAAAAGTGCACGCTACTTTGCTAA
Target: Staphylococcus aureus (S.Aureus)
Target chemistry: Cells
Affinity: 70.86 nM 
Reference: Mitsuma et al. Promising New Assays and Technologies for  the Diagnosis and Management of Infectious  Diseases(Clinical Infectious Diseases)Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: NS-1 Aptamer (ID# 7878)
Aptamer chemistry: DNA
Aptamer sequence: GCAATGGTACGGTACTTCCGCGGTCCGGGGTGGGTGGGTGGTGGGGGGTGCGGGGGGGCGGCCGCAAAAGTGCACGCTACTTTGCTAA
Target: Influenza A virus (IAV) non-stuctural protein (NS1)
Target chemistry: Protein
Affinity: 18.91 nM 
Reference: Woo, H., Kim, K., Lee, J., Shim, H., Cho, S., Lee, W., Ko, H., Keum, Y., Kim, S., Pathinayake, P., Kim, C., and Jeong, Y. "Single-stranded DNA aptamer that specifically binds to the influenza virus NS1 protein suppresses interferon antagonism." Antiviral Research 100.2(2013): 337-345.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Nanobioprobe mediated DNA aptamer (ID# 7894)
Aptamer chemistry: DNA
Aptamer sequence: ATACCAGCTTATTCAATTGGGACAGTCGATGGGACGGCAAACGGACCAGTGTGTGGCGGTAGATAGTAAGAGATAGTAAGTGCAATCT
Target: Trinitrotoluene (TNT)
Target chemistry: Other
Affinity: 100 nM 
Reference: Priyanka, M. S., et al.  "Nanobioprobe mediated DNA aptamers for explosive detection."  Chem. Commun., 2014, 50, 1080 - 1082.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Staphylococcus Aureus RNA Aptamer (ID# 7945)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGAGCGGAAGCGUGCUGGGCCGGGAGUUUUGAUACGGCUUCAUGCAGUAAUGUUUUUAUCAUAACCCAGAGGUCGAUGGAUCCCC
Target: Staphylococcus Aureus
Target chemistry: Cells
Affinity: See Reference nM 
Reference: Seung Ryul Han & Seong-Wook Lee, (2014). In vitro selection of RNA aptamer specific to Staphylococcus aureus. Ann Microbiol 64:883-885 DOI 10.1007/s13213-013-0720-zMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: aptamer 1 (ID# 8019)
Aptamer chemistry: DNA
Aptamer sequence: GCAATGGTACGGTACTTCCGGATGCGGAAACTGGCTAATTGGTGAGGCTGGGGCGGTCGTGCAGCAAAAGTGCACGCTACTTTGCTAA
Target: SARS-CoV nucleocapsid, SARS-CoV-2 nucleocapsid
Target chemistry: Protein
Affinity: 4.93±0.30 nM 
Reference: Cho, S. et al. "Novel system for detecting SARS coronavirus nucleocapsid protein using an ssDNA aptamer". Journal of Bioscience and Bioengineering, 112(2011):535-540.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: AP-1 (ID# 8111)
Aptamer chemistry: DNA
Aptamer sequence: ATACCAGCTTATTCAATTGACCCGTTTCGTTCCCTCTGGGAAGTTTAGCCCAGTTGCCTGGGCGATACCAAGATAGTAAGTGCAATCT
Target: Proprotein Convertase Subtilisin/Kexin 9
Target chemistry: Protein
Affinity: 294 nM 
Reference: Sattari R, Palizban A, Khanahmad H. Single-Strand DNA-Like Oligonucleotide Aptamer Against Proprotein Convertase Subtilisin/Kexin 9 Using CE-SELEX: PCSK9 Targeting Selection. Cardiovasc Drugs Ther. 2020 Aug;34(4):475-485. doi: 10.1007/s10557-020-06986-y. PMID: 32415571.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Seq-2 (ID# 8189)
Aptamer chemistry: DNA
Aptamer sequence: CTATAGCAATGGTACGGTACTTCCTAACTCGTCCCTACCGAGCCTCTCTCTGGTCCTTGCAACTCAAAAGTGCACGCTACTTTGCTAA
Target: Unknown tumor marker - colorectal cancer
Target chemistry: Protein
Affinity: 11.31 nM 
Reference: Li, K., Qi, L., Gao, L. M., Shi, M., Li, J., Liu, Z. W., & Zhao, L. (2019). Selection and preliminary application of a single stranded DNA aptamer targeting colorectal cancer serum. RSC Advances, 9(66), 38867–38876. https://doi.org/10.1039/c9ra04777hMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Nickel (N1) (ID# 7504)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGAGGAUACUACACGUGGAAAAACCAACAAAUUGGGAAAAAUGUUAAGGGUCCACUUCAUGCCAUUGCAUGUAGCAGAAGCUUCCG
Target: Nickel
Target chemistry: Small Organic
Affinity: 800 nM 
Reference: Hoffman, H., et al. "Ni2+-binding RNA motifs with an asymmetric purine-rich internal loop and a G-A base pair." RNA Journal, 3 (1997): 1289-1300.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: HPV-HF cell line (14) (ID# 7700)
Aptamer chemistry: DNA
Aptamer sequence: ATACCAGCTTATTCAATTGGGCGGGGAGTAGGGAGAGGGGTTTCCATCGGCGACAGAGGAGTTATGTGTGTAGATAGTAAGTGCAATCT
Target: HPV-nontumorigenic HF cell line
Target chemistry: Cells
Affinity: 7.1 nM 
Reference: Graham JC, Zarbl H (2012) Use of Cell-SELEX to Generate DNA Aptamers as Molecular Probes of HPV-Associated Cervical Cancer Cells. PLoS ONE 7(4):  e36103. doi:10.1371/journal.pone.0036103Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: JH19 (ID# 7880)
Aptamer chemistry: DNA
Aptamer sequence: GACGCTTACTCAGGTGTGACTCGAGGTGTGACTCGATCTGTGGGGGTTGGGGGGTGGTTTTTCGGAACGAAGGACGCAGATGAAGTCTC
Target: NB4 AML cell line
Target chemistry: Cells
Affinity: 7.57 nM 
Reference: Yang, M. et al. "Developing aptamer probes for acute myelogenous leukemia detection and surface protein biomarker discovery." Journal of Hematology & Oncology 2014, 7:5.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Interleukin 32 (IL-32) (AC3-3) (ID# 7524)
Aptamer chemistry: RNA
Aptamer sequence: GGGUUCACUGCAGACUUGACGAAGCUUCCGGAGAGAAGGGUCAAAGUUGUGCGGGAGUGUGUUGUGGAAUGGAUCCACAUCUACGAAUUC
Target: Interleukin-32 (IL-32)
Target chemistry: Protein
Affinity: 78 nM 
Reference: Kim et al. "Generation of Antagonistic RNA Aptamers Specific to Proinflammatory Cytokine Interleukin-32." Bulletin of the  Korean Chemical Society, 31 (2010):  3561-3566.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Cyclic Guanosine Monophosphate (AR2) (ID# 7588)
Aptamer chemistry: RNA
Aptamer sequence: GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCCUGCGAUGCAGAAAGGUGCUGACGACACAUCGAAACGGUAGCGAGAGCUC
Target: cGMP
Target chemistry: Protein
Affinity: Not Mentioned in Database
Reference: Seetharaman et al. "Immobilized RNA switches for the analysis of complex chemical and biological mixture." Nature Biotechnology, 19(2001): 336-341.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Cyclic Adenosine Monophosphate (AR4) (ID# 7591)
Aptamer chemistry: RNA
Aptamer sequence: GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCUGUGGAAACAGACGUGGCACAUGACUACGUCGAAACGGUAGCGAGAGCUC
Target: cAMP
Target chemistry: Small Organic
Affinity: Not Mentioned in Database
Reference: Seetharaman et al. "Immbolized RNA switches for the analysis of complex chemical and biological mixtures." Nature Biotechnology, 19(2001): 336-341.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Cyclic Cytidine Monophosphate (AR3) (ID# 7592)
Aptamer chemistry: RNA
Aptamer sequence: GGAUAAUAGCCGUAGGUUGCGAAAGCGACCCUGAUGAGCCUUUAGGGCCAAGUGUGGUGAAAGACACACUCGAAACGGUAGCGAGAGCUC
Target: cCMP
Target chemistry: Small Organic
Affinity: Not Mentioned in Database
Reference: Seetharaman et al. "Immobolized RNA switches for the analysis of complex chemical and biological mixture." Nature Biotechnology, 19(2001):336-341.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Fibrinogen (85A/Ap90) (ID# 7609)
Aptamer chemistry: DNA
Aptamer sequence: CCTTCGTTGTCTGCCTTCGTAGGACCGCAGACATCGACGCAGGGAAATTCCGCAAGTCCAGCCAAATGCCACCCTTCAGAATTCGCACCA
Target: Fibrinogen
Target chemistry: Protein
Affinity: 63.8 nM 
Reference: Minyong Li, Na Lin, Zhen Huang, Lupei Du, Craig Altier, Hao Fang and Binghe Wang. "Selecting Aptamers for a Glycoprotein through the Incorporation of the Boronic Acid Moiety." J. Am. Chem. Soc., 2008, 130 (38), pp 12636ƒ??12638.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: H5 Avian Influenza Virus (HAS15-5) (ID# 7617)
Aptamer chemistry: RNA
Aptamer sequence: GGGUUCACUGCAGACUUGACGAAGCUUACAAACAAGAGCAAAAAGGGAGUUGACGUAGACUGUGCGGAAUGGAUCCACAUCUACGAAUUC
Target: Hemagglutinin of the Subtype H5 Avian Influenza Virus
Target chemistry: Protein
Affinity: Not Mentioned in Database
Reference: Park et al. "Selection of an Antiviral RNA Aptamer Against Hemagglutinin of the Subtype H5 Avian Influenza Virus." Nucleic Acid Therapeutics, 21(2011): 395-402.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Salmonella Enteritidis (S25) (ID# 7674)
Aptamer chemistry: RNA
Aptamer sequence: GGGUUCACUGCAGACUUGACGAAGCUUGAGAGAUGCCCCCUGAUGUGCAUUCUUGUUGUGUUGCGGCAAUGGAUCCACAUCUACGAAUUC
Target: Salmonella Enteritidis
Target chemistry: Cells
Affinity: Not Mentioned in Database
Reference: Hyeon, J. et al. Development of RNA Aptamers for Detection of Salmonellas Enteritidis. Journal of Microbiological Methods, 89(2012), 79-82.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Neuropeptide Y (DP3) (ID# 7806)
Aptamer chemistry: 2'-NH2-RNA
Aptamer sequence: GGGAGAAAGGGAAGCUUGAGCAGCAGGAGGGCCGGCGUUAGGGUUAGCGAGCCGAUUGAAAGAAGAAGGAACGAGCGUACGGAUCCGAUC
Target: Neuropeptide Y (NPY)
Target chemistry: Peptide
Affinity: 370 nM 
Reference: D. Proske et al. A Y2 receptor mimetic aptamer directed against neuropeptide Y. J. Biol. Chem. 277(2002):11416-11422.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: 1G8-14 (ID# 7947)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGACAAGAAUAAACGCUCAAGGCAUUUCUGCUAGUCUGGUUGUAAGAUAUUCAACACGUGAGUUUCGACAGGAGGCUCACAACAGGC
Target: Ebola Virus VP35
Target chemistry: Protein
Affinity: 3.7 nM 
Reference: Binning, J., Wang, T., Luthra, P., et al. (2013) Development of RNA aptamers targeting Ebola Virus VP35. Biochemistry, 52(47):8406-8419. doi: 10.1021/bi400704dMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: GVI-1 (ID# 8081)
Aptamer chemistry: DNA
Aptamer sequence: GTCTGAAGTAGACGCAGGAGGGGTGTAGCTCGTTATGATTCGGACAAGACTTACCTTGCGCCTCTGGGATAGTCACACCTGAGTAAGCGT
Target: GCRV-infected CIK
Target chemistry: Cells
Affinity: 220.86 nM 
Reference: Yu, Qing et al. “Generation and characterization of aptamers against grass carp reovirus infection for the development of rapid detection assay.” Journal of fish diseases vol. 44,1 (2021): 33-44. doi:10.1111/jfd.13265Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: GVI-7 (ID# 8083)
Aptamer chemistry: DNA
Aptamer sequence: GTCTGAAGTAGACGCAGGAGTGAACCCACCTCAGGGCATCTTACATTTCTTCTAAGTTGTTACCATGTTTAGTCACACCTGAGTAAGCGT
Target: GCRV-infected CIK
Target chemistry: Cells
Affinity: 176.63 nM 
Reference: Yu, Qing et al. “Generation and characterization of aptamers against grass carp reovirus infection for the development of rapid detection assay.” Journal of fish diseases vol. 44,1 (2021): 33-44. doi:10.1111/jfd.13265Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: i-6 (ID# 8154)
Aptamer chemistry: DNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGATCTCGTGTGTTTGGTTTTAGATTTTTGGAAATTATGATTCCTGTTGGTCCCTATGCGTGCTACCGTGAA
Target: Glycan modification
Target chemistry: Other
Affinity: 29.5 µM 
Reference: Discovery of indole-modified aptamers for highly specific recognition of protein glycoformsAlex M. Yoshikawa, Alexandra Rangel, Trevor Feagin, Elizabeth M. Chun, Leighton Wan, Anping Li, Leonhard Moekl, Michael Eisenstein, Sharon Pitteri, H. Tom SohbioRxiv 2021.03.13.435263; doi: https://doi.org/10.1101/2021.03.13.435263Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Ion-OspA-59 (ID# 8239)
Aptamer chemistry: DNA
Aptamer sequence: TGCTTTTCGTGCGCGCATAAAATACCTTGATACTGTGCCGTATGAAAGCG
Target: Outer Surface Protein A (OspA)
Target chemistry: Protein
Affinity: 2.18 nM 
Reference: Tabb, Joel S., et al. “An Antigen-Targeting Assay for Lyme Disease: Combining Aptamers and SERS to Detect the OSPA Protein.” Nanomedicine: Nanotechnology, Biology and Medicine, vol. 41, 2022, p. 102528., https://doi.org/10.1016/j.nano.2022.102528.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Adenine (12E4) (ID# 7507)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGAGGAUACUACACGUGAUAGGACGAUUAUCGAAAAUCACCAGAUUGGACCCUGGUUAACGAUCCAUUGCAUGUAGCAGAAGCUUCCG
Target: Adenine
Target chemistry: Small Organic
Affinity: 10 nM 
Reference: Meli, M., et al. "Adenine-aptamer complexes: a bipartite RNA site that binds the adenine nucleic base." Journal of Biological Chemistry, 227 (2001): 2104-2111.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Feline Immunodeficiency Virus (F1a) (ID# 7573)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGGAUAUUUUCUCAGACCGUAAGUACCGAAUGUGCUUUUGGCCGAUUUUUGGCCCCUGCAGUUGCAGCAUCGUGAACUAGGAUCCGGG
Target: Feline Immunodeficiency Virus (FIV)
Target chemistry: Protein
Affinity: 1.9 nM 
Reference: Chen, et al. "Inhibitory RNA Ligand to Reverse Transcriptase from Feline Immunodeficiency  Virus." Journal of Biochemistry, 35(1996): 6923-6930.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Hepatitis C Virus Dependent RNA Polymerase (B.2) (ID# 7571)
Aptamer chemistry: RNA
Aptamer sequence: GGGAUGCUUCGGCAUCCCCGAAGCCGCUAUGGACCAGUGGCGCGGCUUCGGCCCGACGGAGUGGUACCGCUUCGGCGGUACGUAAGCUUGGG
Target: Hepatitis C Virus Dependent RNA Polymerase
Target chemistry: Protein
Affinity: 1.5 nM 
Reference: Biroccio et al. "Selection of RNA Aptamers That Are Specific and High-Affinity Ligands of the Hepatitis C Virus RNA-Dependent RNA Polymerase." J. Virol>, 76 (2002):3688-3696.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.