rpgv/AptaCom huggingface dataset:
Aptamer: Chloramphenicol (Cm1) (ID# 7556)
Aptamer chemistry: RNA
Aptamer sequence: GGGAUCACAGUGAAAAAAGACGUGUGAAUGUCACACUGAAAAAAGAUCCC
Target: Chloramphenicol
Target chemistry: Small Organic
Affinity: 110 nM 
Reference: Burke et al. "RNA aptamers to the peptidyl transferase inhibitor chloramphenicol." Chemistry & Biology, 4(1997): 833-843.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Histone H4 N-terminal tail (4.33) (ID# 7721)
Aptamer chemistry: DNA
Aptamer sequence: TGGTGGGGTTCCCGGGAGGGCGGCTACGGGTTCCGTAATCAGATTTGTGT
Target: H4 N-terminal tail
Target chemistry: Protein
Affinity: 1.3 nM 
Reference: Yu et al. "Aptamers can Discriminate Alkaline Proteins with High Specificity."  Chem. Biochem. , 12(2011): 2659-2666.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Digoxin (Truncated D1) (ID# 7770)
Aptamer chemistry: DNA
Aptamer sequence: AGCGAGGGCGGTGTCCAACAGCGGTTTTTTCACGAGGAGGTTGGCGGTGG
Target: Digoxin
Target chemistry: Protein
Affinity: 0.05 nM 
Reference: Z Kiani et al. In vitro selection and characterization of deoxyribonucleic acid aptamers for digoxin. Analytica Chimica Acta 748(2012): 67-72.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: QA-36 (ID# 8089)
Aptamer chemistry: DNA
Aptamer sequence: TGTGCGGGGGAGGGGAGTGGCGCTGTTGGTGCGGGTATAGCGCGTGGTGT
Target: Soft-Shelled Turtle Iridovirus (STIV)
Target chemistry: Other
Affinity: 53.8 nM 
Reference: Li et al. "Characterization of DNA aptamers generated against the soft-shelled turtle iridovirus with antiviral effects." BMC Veterinary Research, 11 (2015): Article number 245.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: HIV-RT 3.17 (ID# 8103)
Aptamer chemistry: DNA
Aptamer sequence: TTATGTAGCATTTATGAAATTTTTAAATCAATTTACTATTGGTGGTATCC
Target: HIV reverse transcriptase (HIV RT)
Target chemistry: Cells
Affinity: 0.38 nM 
Reference: Dunn MR, McCloskey CM, Buckley P, Rhea K, Chaput JC. Generating Biologically Stable TNA Aptamers that Function with High Affinity and Thermal Stability. J Am Chem Soc. 2020 Apr 29;142(17):7721-7724. doi: 10.1021/jacs.0c00641. Epub 2020 Apr 20. PMID: 32298104.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: YFL-6 (ID# 8180)
Aptamer chemistry: RNA
Aptamer sequence: AGGCAGGACACCGTAACCGGTGCATCTATGGCTACTAGCTCTTCCTGCCT
Target: Lactoferrin
Target chemistry: Protein
Affinity: 4.97 nM 
Reference: Yu, F., Li, H., Sun, W., Xu, D. and He, F., 2019. Rapid selection of aptamers based on protein microarray. RSC advances, 9(17), pp.9762-9768.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Apt08rc (ID# 8207)
Aptamer chemistry: DNA
Aptamer sequence: GGGCAGGCAACCTCCCACTATTGAAGACACTACCACCACCACTGCACACA
Target: Cathepsin B
Target chemistry: Protein
Affinity: 10.1-10.7 nM 
Reference: Pereira, A. C., Pina, A. F., Sousa, D., Ferreira, D., Santos-Pereira, C., Rodrigues, J. L., Melo, L. D. R., Sales, G., Sousa, S. F., & Rodrigues, L. R. (2022). Identification of novel aptamers targeting cathepsin B-overexpressing prostate cancer cells. Molecular Systems Design & Engineering, 7(6), 637–650. https://doi.org/10.1039/d2me00022aMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: EC1 (ID# 8208)
Aptamer chemistry: DNA
Aptamer sequence: AATGATGACATTCCGAGGTACCCAGAGTGCGATACTAACCGGCCTGCTTG
Target: Escherichia Coli
Target chemistry: Cells
Affinity: 1.165 nM 
Reference: Deniz Yılmaz, Tuğdem Muslu, Ayhan Parlar, Hasan Kurt, Meral Yüce,SELEX against whole-cell bacteria resulted in lipopolysaccharide binding aptamers, Journal of Biotechnology, Volume 354, 2022, Pages 10-20, ISSN 0168-1656.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: LM3 (ID# 8209)
Aptamer chemistry: DNA
Aptamer sequence: CCGTCCCGGTAGTCTGAGCTTACAATGTCTGATTGGAAATGCACACCAAG
Target: Listeria monocytogenes
Target chemistry: Cells
Affinity: 8.89 nM 
Reference: Deniz Yılmaz, Tuğdem Muslu, Ayhan Parlar, Hasan Kurt, Meral Yüce, SELEX against whole-cell bacteria resulted in lipopolysaccharide binding aptamers, Journal of Biotechnology, Volume 354, 2022, Pages 10-20, ISSN 0168-1656.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Moenomycin A (C2) (ID# 7494)
Aptamer chemistry: 2'-NH2-RNA
Aptamer sequence: GGAGGUCGACCUCGCGCGAGGAGGGUGGAGGGUCGUAGAGCGCGUAGGAGG
Target: Moenomycin A
Target chemistry: Small Organic
Affinity: 350 nM 
Reference: Heike, S., et al. "Aptamers that bind to the antibiotic moenomycin A." Bioorganic & Medicinal Chemistry, 9 (2001): 2557-2563.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Human Nonpancreatic Secretory Phospholipase A2 (Aptamer 15) (ID# 7536)
Aptamer chemistry: 2'-NH2-RNA
Aptamer sequence: GGGAAAAGAGACGGCCGGCGCCAUAGCCGAGAUCCGAGGUGUUGCCGAGAA
Target: Human Nonpancreatic Secretory Phospholipase A2  (hnps-PLA2)
Target chemistry: Small Organic
Affinity: 1.7 nM 
Reference: Bridonneau, P., et al. "High-Affinity Aptamers Selectively Inhibit Human Nonpancreatic Secretory Phospholipase A2 (hnps-PLA2)." Journal of Medicinal Chemistry, 41(1998): 778-786.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Neurotrophin receptor, TrkB (C4-3) (ID# 7691)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGGAGGACGAUGCGGUCGUAUUAUCCGCUGCACGCCAGACGACUCGCCCGA
Target: Neurotrophin receptor, TrkB
Target chemistry: Protein
Affinity: 2.1 nM 
Reference: Huang, Y. (2012). RNA aptamer-based functional ligands of the neurotrophin receptor, TrkB. J. Pharmacol. Exp. Ther. 82(2012):623-635.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Periostin Aptamer (PNDA-3) (ID# 7890)
Aptamer chemistry: RNA
Aptamer sequence: ACGAGTTGTCGCATGTGCGGTTCAGTCTGGTCCTTCAGCACCGTACAACAA
Target: Periostin
Target chemistry: Protein
Affinity: 1.07 nM 
Reference: Lee, Y., Kim, I., Park, S., Kim, Y., Wu, S., Lee, J., Noh, D., Kim, K., Ryu, S. and Suh, P. "Periostin-binding DNA aptamer inhibits breast cancer growth and metastasis." The American Society of Gene & Cell Therapy 21.5 (2013): 1004-13.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Tr-8 (ID# 8036)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGGACGAUGCGGGCCGUUGUUGUGUGCCGCCCCAGACGACUCGCCCGA
Target: CD25
Target chemistry: Protein
Affinity: 35.7 nM 
Reference: Veeramani, Suresh,et al."An RNA aptamer-based biomarker platform demonstrates high soluble CD25 occupancy by IL2 in the serum of follicular lymphoma patients" American Association for Cancer Research 7, (2019) 1511-1522Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Tr-1 (ID# 8037)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGGACGAUGCGGUCCUGUCGUCUGUUCGUCCCCAGACGACUCGCCCGA
Target: IL2-CD25 Complex
Target chemistry: Protein
Affinity: 67.8 nM 
Reference: Veeramani, Suresh,et al."An RNA aptamer-based biomarker platform demonstrates high soluble CD25 occupancy by IL2 in the serum of follicular lymphoma patients" American Association for Cancer Research 7, (2019) 1511-1522Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Tr-7 (ID# 8038)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGGACGAUGCGGUGAGUCGUUCCCUUCGUCCCCAGACGACUCGCCCGA
Target: IL2-CD25 Complex
Target chemistry: Protein
Affinity: 45.0 nM 
Reference: Veeramani, Suresh,et al."An RNA aptamer-based biomarker platform demonstrates high soluble CD25 occupancy by IL2 in the serum of follicular lymphoma patients" American Association for Cancer Research 7, (2019) 1511-1522Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Fructose-bisboronic acid aptamer-sensor (ID# 8046)
Aptamer chemistry: DNA
Aptamer sequence: CTCTCGGGACGACGGCTGGCACGTTTGGTTCAAGAATGTGGGTGTCGTCCC
Target: Fructose
Target chemistry: Small Organic
Affinity: 4 nM 
Reference: Yang KA, Barbu M, Halim M, et al. Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors. Nat Chem. 2014;6(11):1003-1008. doi:10.1038/nchem.2058Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Galactose-bisboronic acid aptamer-sensor (ID# 8047)
Aptamer chemistry: DNA
Aptamer sequence: CTCTCGGGACGACCACTACGCATAGTTTCTATCGCCAGGAAGGGTCGTCCC
Target: Galactose
Target chemistry: Small Organic
Affinity: 13 nM 
Reference: Yang KA, Barbu M, Halim M, et al. Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors. Nat Chem. 2014;6(11):1003-1008. doi:10.1038/nchem.2058Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Phenylalanine-Cp*Rh(III) sensor (ID# 8048)
Aptamer chemistry: DNA
Aptamer sequence: CTCTCGGGACGACGGACGCTAATCTTACAAGGGCGTAGTGTATGTCGTCCC
Target: Phenylalanine
Target chemistry: Small Organic
Affinity: 3.2 nM 
Reference: Yang KA, Barbu M, Halim M, et al. Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors. Nat Chem. 2014;6(11):1003-1008. doi:10.1038/nchem.2058Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Tryptophan-Cp*Rh(III) sensor (ID# 8050)
Aptamer chemistry: DNA
Aptamer sequence: CTCTCGGGACGACCGCGGTAGTCTTAACCTAAAGCGGTGTCAGGTCGTCCC
Target: Tryptophan
Target chemistry: Small Organic
Affinity: 1.2 µM 
Reference: Yang KA, Barbu M, Halim M, et al. Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors. Nat Chem. 2014;6(11):1003-1008. doi:10.1038/nchem.2058Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Apt01 (ID# 8200)
Aptamer chemistry: DNA
Aptamer sequence: TGGGGGGCAAGCAATTGGTGTGTGGTGTAGCATCCCCCTGTACCGCGCGGG
Target: CatB
Target chemistry: Protein
Affinity: 9.0 nM 
Reference: Periera, A., Pina, A., Sousa, D., Ferriera, D., Periera, C., Rodrigues, J., Melo, L., Sales, G., Sousa, S., & Rodrigues, L. (2022). Identification of Novel Aptamers Targeting Cathepsin B-Overexpressing Prostate Cancer Cells, 1–14. https://doi.org/10.1039/d2me00022aMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: SARS-CoV-2 Aptamer 1C (ID# 8006)
Aptamer chemistry: DNA
Aptamer sequence: CAGCACCGACCTTGTGCTTTGGGAGTGCTGGTCCAAGGGCGTTAATGGACA
Target: RBD of the Spike glycoprotein from SARS-CoV-2
Target chemistry: Protein
Affinity: 5.8 nM 
Reference: Song, Yanling; Song, Jia; Wei, Xinyu; Huang, Mengjiao; Sun, Miao; Zhu, Lin; et al. (2020): Discovery of Aptamers Targeting Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein. ChemRxiv. Preprint. https://doi.org/10.26434/chemrxiv.12053535.v2Song, Y., Song, J., Wei, X., Huang, M., Sun, M., Zhu, L., Lin, B., Shen, H., Zhu, Z., and C. Yang. 2020. Discovery of Aptamers Targeting the Receptor-Binding Domain of the SARS-CoV‑2 Spike Glycoprotein. Analytical Chemistry 2020, 92, 9895−9900. https://dx.doi.org/10.1021/acs.analchem.0c01394Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: A2 (ID# 8125)
Aptamer chemistry: DNA
Aptamer sequence: GAAGAGTAGATGAAACGTTTTTTCGCCCGATAAAAGGGACGTGCGTCAGACA
Target: M0-like and M2-like macrophages and monocytes
Target chemistry: Cells
Affinity: 20-45 nM 
Reference: Sylvestre, M.; Saxby, C.; Kacherovsky, N.; Gustafson, H.; Salipante, S.; Pun, S. Identification of a DNA Aptamer That Binds to Human Monocytes and Macrophages. Bioconjug. Chem. 2020 Aug 9; 31(8): 1899-1907. DOI: 10.1021/acs.bioconjchem.0c00247.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: #AP-Cell 1 (ID# 8146)
Aptamer chemistry: DNA
Aptamer sequence: CGGGACAAGACAACGAACGAACAGGAAGAGAACCGGAATGCAGACGTCAGGG
Target: Aspartate β-Hydroxylase (ASPH)
Target chemistry: Protein
Affinity: 47.51 ± 5.86 nM 
Reference: Hadi Bakhtiari, Abbas Ali Palizban, Hossein Khanahmad, and Mohammad Reza MofidACS Omega 2021 6 (16), 11005-11014DOI: 10.1021/acsomega.1c00876Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: #AP-Cell 3 (ID# 8147)
Aptamer chemistry: DNA
Aptamer sequence: CCGTATCGCCCAGGCAACTGGGCTAAACTTCCCAGAGGGAACGAAACCTGGG
Target: Aspartate β-Hydroxylase (ASPH)
Target chemistry: Protein
Affinity: 65.23 ± 9.61 nM 
Reference: Hadi Bakhtiari, Abbas Ali Palizban, Hossein Khanahmad, and Mohammad Reza MofidACS Omega 2021 6 (16), 11005-11014DOI: 10.1021/acsomega.1c00876Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: sk6Ea (ID# 7998)
Aptamer chemistry: DNA
Aptamer sequence: TCACGCCCGATAAGGGCGATGCCGATCCCTGTGGCCGTAGGGCAGTCCCCTAG
Target: SK-BR-3 cells (HER2 positive)
Target chemistry: Cells
Affinity: 34.79\u202c-63.85 nM 
Reference: Liu, M.; Wang, Z.; Tan, T.; Chen, Z.; Mou, X.; Yu, X.; Deng, Y.; Lu, G.; He, N. An Aptamer-Based Probe for Molecular Subtyping of Breast Cancer. Theranostics. 2018, 8, 5772-5783.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: S6-1b (ID# 8136)
Aptamer chemistry: DNA
Aptamer sequence: CACAGGTTCCAGGTAATACCTAAGGGTATGCTCTCGCCTATTATATGGAGCAC
Target: Membrane protein of glioma cell line SHG44
Target chemistry: Protein
Affinity: 3.1-44 nM 
Reference: Lin, N.; Wu, L.; Xu, X.; Wu, Q.; Wang, Y.; Shen, H.; Song, Y.; Wang, H., Zhu, Z.; Kang, D.; Yang, C. Aptamer Generated by Cell-SELEX for Specific Targeting of Human Glioma Cells. ACS Appl. Mater. Interfaces. 2021 Mar 3; 13(8): 9306-9315. DOI: 10.1021/acsami.0c11878.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Phorate (SS4-54) (ID# 7681)
Aptamer chemistry: DNA
Aptamer sequence: AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG
Target: Phorate
Target chemistry: Small Organic
Affinity: 1.43 µM 
Reference: Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. Biotechnol Lett, 2012(34), 869-874. doi: 10.1007/s10529-012-0850-6Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Profenofos (SS4-54) (ID# 7682)
Aptamer chemistry: DNA
Aptamer sequence: AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG
Target: Profenofos
Target chemistry: Small Organic
Affinity: 1.25 µM 
Reference: Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. Biotechnol Lett, 2012(34), 869-874. doi: 10.1007/s10529-012-0850-6Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Isocarbophos (SS4-54) (ID# 7683)
Aptamer chemistry: DNA
Aptamer sequence: AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG
Target: Isocarbophos
Target chemistry: Small Organic
Affinity: 0.9 µM 
Reference: Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. Biotechnol Lett, 2012(34), 869-874. doi: 10.1007/s10529-012-0850-6Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Omethoate (SS4-54) (ID# 7684)
Aptamer chemistry: DNA
Aptamer sequence: AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAG
Target: Omethoate
Target chemistry: Small Organic
Affinity: 2 µM 
Reference: Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. Biotechnol Lett, 2012(34), 869-874. doi: 10.1007/s10529-012-0850-6Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: A15 (ID# 7919)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGGACGAUGCGGCGUAUUGCGCGAGGAUUAUCCGCUCAUCGUUGUUGUUGUGCAGACGACUCGCCCGA
Target: Penetrating the Blood Brain Barrier (BBB)
Target chemistry: Other
Affinity: . nM 
Reference: Congsheng Cheng, Yong Hong Chen, Kim A Lennox, Mark A Behlke, Beverly L Davidson, "In vivo SELEX for Identification of Brain-penetrating Aptamers" Molecular Therapy-Nucleic Acids (2013)2, e67, American Society of Gene & Cell TherapyMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Uranium DNAzyme (ID# 7950)
Aptamer chemistry: DNA
Aptamer sequence: CACGTCCATCTCTGCAGTCGGGTAGTTAAACCGACCTTCAGACATAGTAAGGGG
Target: Uranium
Target chemistry: Other
Affinity: n/a nM 
Reference: Sai Jin Xiao, Jun Zuo, Zhi Qiang Zhu, Yong Zhong Ouyang, Xing Lei Zhang, Huan Wen Chen, & Li Zhang (2015) Highly Sensitive DNAzyme Sensor for Selective Detection of Trace Uranium in Ore and Natural Water Samples. Sensors and Actuators B 210 (2015) 656-660Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: H2 (ID# 8226)
Aptamer chemistry: DNA
Aptamer sequence: GGGCCGTCGAACACGAGCATGGTGCGTGGACCTAGGATGACCTGAGTACTGTCC
Target: HER-2
Target chemistry: Protein
Affinity: 270 nM 
Reference: "In vitro HER2 protein-induced affinity dissociation of carbon nanotube-wrapped anti-HER2 aptamers for HER2 protein detection" J. H. Niazi, S. K. Verma, S. Niazi and A. Qureshi, Analyst, 2014DOI:	https://doi.org/10.1039/C4AN01665CMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Phorate (SS2-55) (ID# 7677)
Aptamer chemistry: DNA
Aptamer sequence: AAGCTTGCTTTATAGCCTGCAGCGATTCTTGATCGGAAAAGGCTGAGAGCTACGC
Target: Phorate
Target chemistry: Small Organic
Affinity: 1.11 µM 
Reference: Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. Biotechnol Lett, 2012(34), 869-874. doi: 10.1007/s10529-012-0850-6Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Profenofos (SS2-55) (ID# 7678)
Aptamer chemistry: DNA
Aptamer sequence: AAGCTTGCTTTATAGCCTGCAGCGATTCTTGATCGGAAAAGGCTGAGAGCTACGC
Target: Profenofos
Target chemistry: Small Organic
Affinity: 1 µM 
Reference: Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. Biotechnol Lett, 2012(34), 869-874. doi: 10.1007/s10529-012-0850-6Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Isocarbophos (SS2-55) (ID# 7679)
Aptamer chemistry: DNA
Aptamer sequence: AAGCTTGCTTTATAGCCTGCAGCGATTCTTGATCGGAAAAGGCTGAGAGCTACGC
Target: Isocarbophos
Target chemistry: Small Organic
Affinity: 0.83 µM 
Reference: Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. Biotechnol Lett, 2012(34), 869-874. doi: 10.1007/s10529-012-0850-6Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Omethoate (SS2-55) (ID# 7680)
Aptamer chemistry: DNA
Aptamer sequence: AAGCTTGCTTTATAGCCTGCAGCGATTCTTGATCGGAAAAGGCTGAGAGCTACGC
Target: Omethoate
Target chemistry: Small Organic
Affinity: 2.5 µM 
Reference: Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. Biotechnol Lett, 2012(34), 869-874. doi: 10.1007/s10529-012-0850-6Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: L-vasopressin (ID# 7820)
Aptamer chemistry: L-DNA
Aptamer sequence: TCACGTGCATGATAGACGGCGAAGCCGTCGAGTTGCTGTGTGCCGATGCACGTGA
Target: L-vasopressin/arginine vasopressin/AVP/ADH
Target chemistry: Peptide
Affinity: 1.2 µM 
Reference: K. P. Williams, D. P. Bartel, et al. Bioactive and nuclease-resistant l-DNA ligand of vasopressin. Proc. Natl. Acad. Sci., USA. 94(1997): 11285-11290.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: A14 (ID# 7921)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGGACGAUGCGGGUAGCCUUUCGGUGGUCCGUUAUCUCCACAUCACGUCUGCAGACGACUCGCCCGA
Target: Penetrating the Blood Brain Barrier (BBB)
Target chemistry: Other
Affinity: Not Mentioned in Database
Reference: Congsheng Cheng, Yong Hong Chen, Kim A Lennox, Mark A Behlke, Beverly L Davidson, "In vivo SELEX for Identification of Brain-penetrating Aptamers" Molecular Therapy-Nucleic Acids (2013)2, e67, American Society of Gene & Cell TherapyMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: A09 (ID# 7923)
Aptamer chemistry: RNA
Aptamer sequence: GGGAGGACGAUGCGGUUACCUUUGUCCAGCAUGUUCGGAUUCGGCACCUGGUCCCAGACGACUCGCCCGA
Target: Penetrating the Blood Brain Barrier (BBB)
Target chemistry: Other
Affinity: Not Mentioned in Database
Reference: Congsheng Cheng, Yong Hong Chen, Kim A Lennox, Mark A Behlke, Beverly L Davidson, "In vivo SELEX for Identification of Brain-penetrating Aptamers" Molecular Therapy-Nucleic Acids (2013)2, e67, American Society of Gene & Cell TherapyMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Antibac1 (ID# 7976)
Aptamer chemistry: DNA
Aptamer sequence: TCGCGCGAGTCGTCTGGGGACAGGGAGTGCGCTGCTCCCCCCGCATCGTCCTCCC
Target: peptidoglycan
Target chemistry: Other
Affinity: 268.5 nM 
Reference: A Graziani et al. High efficiency binding aptamers for a wide range of sepsis 1 bacterial agents. JMB Papers in Press. 2017: JMB16-11004.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.