rpgv/AptaCom huggingface dataset:
Aptamer: Ky2 Aptamer (ID# 7908)
Aptamer chemistry: DNA
Aptamer sequence: TGGGGGTTGAGGCTAAGCCGA
Target: Kanamycin
Target chemistry: Other
Affinity: 78.8 nM 
Reference: Kyung-Mi Song, Minseon Cho, Hunho Jo, Kyoungin Min, Sung Ho Jeon, Taisun Kim, Min Su Han, Ja Kang Ku, Changill Ban, "Gold nanoparticle-based colorimetric detection of kanamycin using a DNA aptamer". Anal. Biochem. 415 (2011) 175-181.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Mercury II (Hg2+) (ID# 7707)
Aptamer chemistry: DNA
Aptamer sequence: TTCTTTCTTCCCCTTGTTTGTT
Target: Mercury II (Hg2+)
Target chemistry: Other
Affinity: Not Mentioned in Database
Reference: A. Ono and H. Togashi. "Highly selective oligonucleotide-based sensor for mercury(II) in aqueous solutions." Angew. Chem. Int. Ed. 43(2004):4300-4302.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: SL1025 (ID# 7973)
Aptamer chemistry: Chimeric
Aptamer sequence: GGCAGGGGAAACACGAAGCGGG
Target: Interleukin 6 (IL-6), cytokine
Target chemistry: Protein
Affinity: 0.2 nM 
Reference: Gupta, Shashi, et al. "Chemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor." Journal of Biological Chemistry 289.12 (2014): 8706-8719.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Human Immunoglobulin G (IgG) (Apt 8) (ID# 7461)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGAGGUGCUCCGAAAGGAACUCC
Target: hlgG-Fc
Target chemistry: Protein
Affinity: 75 nM 
Reference: Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Glycated human serum albumin (GHSA) (ID# 7967)
Aptamer chemistry: DNA
Aptamer sequence: TGCGGTTGTAGTACTCGTGGCCG
Target: GHSA
Target chemistry: Protein
Affinity: 5.78 µM 
Reference: Apiwat et al. Graphene based aptasensor for glycated albuminin diabetes mellitus   diagnosis and monitoring. Biosensors and Bioelectronics 82(2016)140ƒ??145.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: a-Synuclein Oligomers (T-SO508) (ID# 7728)
Aptamer chemistry: DNA
Aptamer sequence: GCCTGTGGTGTTGGGGCGGGTGCG
Target: a-synuclein oligomers
Target chemistry: Protein
Affinity: 68 nM 
Reference: K Tsukakoshi. Selection of DNA aptamers that recognize a-synuclein oligomers using a competitive screening method. Anal Chem. 84(2012): 5542-5547Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: R24 (ID# 8215)
Aptamer chemistry: RNA
Aptamer sequence: GGAGGAGGAGGAGGAGGAGGAGGA
Target: Bovine PrP
Target chemistry: Protein
Affinity: 61 nM 
Reference: Mashima, T., Lee, JH., Kamatari, Y.O. et al. Development and structural determination of an anti-PrPC aptamer that blocks pathological conformational conversion of prion protein. Sci Rep 10, 4934 (2020).Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Adenosine/ATP (DH25.42) (ID# 7509)
Aptamer chemistry: DNA
Aptamer sequence: CCTGGGGGAGTATTGCGGAGGAAGG
Target: Adenosine and ATP
Target chemistry: Small Organic
Affinity: 6 µM 
Reference: Huizenga and Szostak. "A DNA Aptamer That Binds Adenosine and ATP." Biochemistry, 34 (1995): 656-665.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: PC12 Cells (Aptamer17a) (ID# 7618)
Aptamer chemistry: DNA
Aptamer sequence: GGTTGGATGTAAGGTTGGAGGGGGG
Target: PC12 Cells
Target chemistry: Cells
Affinity: Not Mentioned in Database
Reference: Liu et al. "Dissection of the Functional Structure of Aptamer17, Which Specifically Recognizes Differential PC12 Cells." Nucleic Acid Therapeutics, 21(2011): 225-229.      Wang et al. "Single-stranded DNA Aptamers thatBbind Differentiated but not Parental Cells: Subtractive Systematic Evolution of Ligands by Exponential Enrichment." J. Biotechnol., 102(2003): 15-22.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: V7t1 targeting VEGF-121 (ID# 7733)
Aptamer chemistry: DNA
Aptamer sequence: TGTGGGGGTGGACGGGCCGGGTAGA
Target: VEGF-121
Target chemistry: Protein
Affinity: 1.1 nM 
Reference: Nonaka,Y., Sode, K., and Ikebukuro, K.(2010) "Screening and Improvement of an Anti-VEGF DNA Aptamer." Molecules, 15, 215-225.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: V7t1 targeting VEGF-165 (ID# 7734)
Aptamer chemistry: DNA
Aptamer sequence: TGTGGGGGTGGACGGGCCGGGTAGA
Target: VEGF-165
Target chemistry: Protein
Affinity: 1.4 nM 
Reference: Nonaka,Y., Sode, K., and Ikebukuro, K.(2010) "Screening and Improvement of an Anti-VEGF DNA Aptamer." Molecules, 15, 215-225.     Stejskalov?­, Anna & Oliva, Nuria & J England, Frances & Almquist, Benjamin. (2019). Biologically Inspired, Cell-Selective Release of Aptamer-Trapped Growth Factors by Traction Forces. Advanced Materials. 1806380. 10.1002/adma.201806380.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Tumor necrosis factor-alpha (TNFa) (VR11) (ID# 7741)
Aptamer chemistry: DNA
Aptamer sequence: TGGTGGATGGCGCAGTCGGCGACAA
Target: Tumor necrosis factor-alpha (TNFa)
Target chemistry: Protein
Affinity: 7 nM 
Reference: E Orava et al. A short DNA aptamer that recognizes TNFa and blocks its activity in vitro. ACS Chem. Biol. (2012) Accepted for print. DOI: 10.1021/cb3003557.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Anionic Porphyrins (ST1) (ID# 7849)
Aptamer chemistry: DNA
Aptamer sequence: AACGTGGGAGGGCGGTGGTGTTGAA
Target: N-methylmesoporphyrin IX (NMM), mesoporphyrin IX (MPIX), and other metalloderivatives
Target chemistry: Small Organic
Affinity: 0.7 µM 
Reference: Y Li, CR Geyer, and D Sen. (1996) Recognition of anionic porphyrins by DNA aptamers. Biochem. 35:6911-6922.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: S2.2 (ID# 7974)
Aptamer chemistry: DNA
Aptamer sequence: GCAGTTGATCCTTTGGATACCCTGG
Target: MUC1
Target chemistry: Protein
Affinity: 0.135 nM 
Reference: D Seleci et al. Aptamer mediated niosomal drug delivery. RSC Adv 6(2016): 87910-87918.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: S22 (ID# 8157)
Aptamer chemistry: DNA
Aptamer sequence: GCAGTTGATCCTTTGGATACCCTGG
Target: MUC-1
Target chemistry: Protein
Affinity: 0.010 - 1000 nM 
Reference: Wen W., et al. "An insertion approach electrochemical aptasensor for mucin 1 detection based on exonuclease-assisted target recycling." Biosensors and Bioelectronics, 71 (2015): 13–17. doi: https://doi.org/10.1016/j.bios.2015.04.001Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: R12-A-12 (ID# 8216)
Aptamer chemistry: RNA
Aptamer sequence: GGAGGAGGAGGAAGGAGGAGGAGGA
Target: Bovine PrP
Target chemistry: Protein
Affinity: Not Mentioned in Database
Reference: Mashima, T., Lee, JH., Kamatari, Y.O. et al. Development and structural determination of an anti-PrPC aptamer that blocks pathological conformational conversion of prion protein. Sci Rep 10, 4934 (2020).Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Nucleolin aptamer (AS1411) (ID# 7675)
Aptamer chemistry: DNA
Aptamer sequence: GGTGGTGGTGGTTGTGGTGGTGGTGG
Target: Nucleolin
Target chemistry: Protein
Affinity: Not Mentioned in Database
Reference: Kotula J, Sullenger B, et al. 2012. Aptamer-mediated delivery of splice-switching oligonucleotides to the nuclei of cancer cells. Nucleic Acid and Therapeutics 22.3:187-195.  Li, L. et al. 2014. Aptamer photoregulation in vivo. PNAS 11.48: 17099-103.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: VEGF (SL2-B aptamer) (ID# 7688)
Aptamer chemistry: DNA
Aptamer sequence: CAATTGGGCCCGTCCGTATGGTGGGT
Target: VEGF (165)
Target chemistry: Protein
Affinity: 0.5 nM 
Reference: Kaur H, Yung L-YL (2012) Probing High Affinity Sequences of DNA Aptamer against VEGF165. PLoS ONE 7(2): e31196. doi:10.1371/journal.pone.0031196Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Anti-VEGF165 (ID# 7727)
Aptamer chemistry: DNA
Aptamer sequence: CCCGTCTTCCAGACAAGAGTGCAGGG
Target: Recombinant Human Vascular Endothelial Growth Factor
Target chemistry: Protein
Affinity: 0.92 nM 
Reference: A Potty et al. Biophysical characterization of DNA aptamer interactions with vascular endothelial growth factor. Biopolymers 91(2008):145-155.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: StrepApt5 (ID# 7906)
Aptamer chemistry: DNA
Aptamer sequence: GGGAACGCACCGATCGCAGGTTTCCC
Target: Streptavidin
Target chemistry: Protein
Affinity: 35 nM 
Reference: Ruigrok, Vincent J. B., et al. "Kinetic and Stoichiometric Characterisation of Streptavidin-Binding Aptamers." ChemBioChem 13 (2012): 829-836. Print.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Ricin A-chain (RTA) Aptamer (RA80.1.d2 – 31RA) (ID# 7953)
Aptamer chemistry: RNA
Aptamer sequence: GGCGAACAGGGGACGAGCAAGACGCC
Target: Ricin A-chain (RTA)
Target chemistry: Protein
Affinity: 7.4 nM 
Reference: (1) Bogomolova, A., Aldissi, M. ƒ??Real-time and label-free analyte detection in a flow-through mode using immobilized fluorescent aptamer/quantum dots molecular switches.ƒ? Biosensors and Bioelecgtronics, 66 (2015): 290-296.      (2) Hesselberth, J., et al. ƒ??In vitro Selection of RNA Molecules That Inhibit the Activity of Ricin A-chain.ƒ? Journal of Biological Chemistry, 275, 7 (2000): 4937-4942.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Reactive Green 19 (GR-30) (ID# 7502)
Aptamer chemistry: DNA
Aptamer sequence: GCAGGGGCGTTCGGGGGGTACCGCTGC
Target: Reactive Green 19
Target chemistry: Small Organic
Affinity: 33 µM 
Reference: Ellington and Szostak. "Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structures." Nature, 355 (1992): 850-852.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: L-arginine (12-79) (ID# 7848)
Aptamer chemistry: DNA
Aptamer sequence: GACCAGGGCAAACGGTAGGGAGTGGTC
Target: L-arginine
Target chemistry: Small Organic
Affinity: ~2.5 mM 
Reference: K Harada and A Frankel. (1995) Identification of two novel arginine binding DNAs. EMBO J, 14(23): 5798-5811.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Aptamer Beacon (ID# 8174)
Aptamer chemistry: DNA
Aptamer sequence: ACCTGGGGGAGTATTGCGGAGGAAGGT
Target: adenosine
Target chemistry: Protein
Affinity: 6.0 nM 
Reference: Zhang JQ, Wang YS, Xue JH, He Y, Yang HX, Liang J, Shi LF, Xiao XL. A gold nanoparticles-modified aptamer beacon for urinary adenosine detection based on structure-switching/fluorescence-"turning on" mechanism. J Pharm Biomed Anal. 2012 Nov;70:362-8. doi: 10.1016/j.jpba.2012.05.032. Epub 2012 Jun 1. PMID: 22717140.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: DNAzymeMB (Part of Lysozyme Aptasensor) (ID# 7581)
Aptamer chemistry: DNA
Aptamer sequence: AGGGACGGGCTAAGTAACTGTGGAGGGT
Target: N/A: See additional comments.
Target chemistry: Protein
Affinity: Not Mentioned in Database
Reference: Fu et al. "An ultrasensitive peroxidase DNAzyme-associated aptasensor that utilizes a target-triggered enzymatic signal amplification strategy." Chemical Communications, 47(2011): 9876-9878.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: GRK2 (C13.28) (ID# 7698)
Aptamer chemistry: RNA
Aptamer sequence: GGCAGACCAUACGGGAGAGAAACUUGCC
Target: G protein-coupled receptor kinase 2
Target chemistry: Protein
Affinity: 1.2 nM 
Reference: Tesmer et al., Molecular Mechanism for Inhibition of G Protein-Coupled Receptor Kinase 2 by a Selective RNA Aptamer, Structure (2012), doi:10.1016/j.str.2012.05.002Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: L-arginine (12-28 hairpin) (ID# 7847)
Aptamer chemistry: DNA
Aptamer sequence: GGGATCGAAACGTAGCGCCTTCGATCCC
Target: L-arginine
Target chemistry: Small Organic
Affinity: ~2.5 nM 
Reference: K Harada and A Frankel. (1995) Identification of two novel arginine binding DNAs. EMBO J, 14(23): 5798-5811.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Insulin-Linked Polymorphic Region Two-Repeat (ILPR2) (ID# 7863)
Aptamer chemistry: DNA
Aptamer sequence: ACAGGGGTGTGGGGACAGGGGTGTGGGG
Target: Insulin
Target chemistry: Peptide
Affinity: Not Mentioned in Database
Reference: Connor A C, McGown L B, et al. (2006) Insulin Capture by an Insulin-Linked Polymorphic Region G-Quadruplex DNA Oligonucleotide. J Am Chem Soc. 128: 4986-4991.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Mitomer2 (ID# 7929)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: UCCCGAUUACUGUACAUACCUUAGCCCAUAGCUGGCUGC
Target: Mitochondria
Target chemistry: Other
Affinity: . nM 
Reference: Yuri Tawaraya, Mamoru Hyodo, Mst Naznin Ara, Yuma Yamada, and Hideyoshi Harashima, ƒ??RNA Aptamers for Targeting Mitochondria Using a Mitochondria-Based SELEX Methodƒ? Biol. Pharm. Bull. 37(8) 1411-1415 (2014)Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: CH1S-3 (ID# 8122)
Aptamer chemistry: DNA
Aptamer sequence: GTCCAGGGTTCCAAGGTGCTTCGTGGAC
Target: Trastuzumab
Target chemistry: Antibody
Affinity: 10.3 nM 
Reference: Chen, K.; Zhou, J.; Shao, Z.; Liu, J.; Song, J.; Wang, R.; Li, J.; Tan, W. Aptamers as Versatile Molecular Tools for Antibody Production Monitoring and Quality Control. J. Am. Chem. Soc. 2020 Jun 9; 142(28): 12079-12086. PMID 32516525. DOI: 10.1021/jacs.9b13370.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Sulforhodamine B (Clone 73 – min) (ID# 7549)
Aptamer chemistry: DNA
Aptamer sequence: CCGGCCAAGGGTGGGAGGGAGGGGGCCGG
Target: Sulforhodamine B
Target chemistry: Small Organic
Affinity: 190 nM 
Reference: Wilson C, Szostak J. (1998) Isolation of a fluorophore-specific DNA aptamer with redox activity. Chem Biol. 5(11):609-617.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Thrombin (29mer) (ID# 7699)
Aptamer chemistry: DNA
Aptamer sequence: AGTCCGTGGTAGGGCAGGTTGGGGTGACT
Target: Thrombin
Target chemistry: Protein
Affinity: 0.5 nM 
Reference: Tasset, D. (1997). Oligonucleotide inhibitors of human thrombin that bind distinct epitopes. J. Mol. Biol., 1997(272), 688-698.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Kit-129 (ID# 7866)
Aptamer chemistry: DNA
Aptamer sequence: GCTCAACGCGGGACGGCTCTCCCATTGAC
Target: CD117 (c-kit)
Target chemistry: Protein
Affinity: 12.21 nM 
Reference: Development of an Efficient Targeted Cell-SELEX  Procedure for DNA Aptamer Reagents   Susanne Meyer et al. 2013Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: StrepApt 2 (ID# 7905)
Aptamer chemistry: DNA
Aptamer sequence: GGGAATCGCCACCCGACGCAGGGTTTCCC
Target: Streptavidin
Target chemistry: Protein
Affinity: 77 nM 
Reference: Ruigrok, Vincent J. B., et al. "Kinetic and Stoichiometric Characterisation of Streptavidin-Binding Aptamers." ChemBioChem 13 (2012): 829-836. Print.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: 1-PA (ID# 7917)
Aptamer chemistry: RNA
Aptamer sequence: GATGTGGGTGTAGTTGGAGGGTAAACGTT
Target: Anthrax Protective Antigen (PA)
Target chemistry: Protein
Affinity: 8.53 nM 
Reference: Byul Nim Oh, Sungeun Lee, Hye-Yeon Park, Jin-Ook Baeg, Moon-Young Yoon, and Jinheung Kim. 2011. Reference: Sensitive fluorescence assay of anthrax protective antigen with two new DNA aptamers and their binding properties. Analyst, 2011, 136, 3384. DOI: 10.1039/c0an00978dMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: 2-PA (ID# 7918)
Aptamer chemistry: DNA
Aptamer sequence: CAGACCGTAAGGGATGCCGCCTAAACACC
Target: Anthrax Protective Antigen (PA)
Target chemistry: Protein
Affinity: 1.51 nM 
Reference: Byul Nim Oh, Sungeun Lee, Hye-Yeon Park, Jin-Ook Baeg, Moon-Young Yoon, and Jinheung Kim. 2011. Reference: Sensitive fluorescence assay of anthrax protective antigen with two new DNA aptamers and their binding properties. Analyst, 2011, 136, 3384. DOI: 10.1039/c0an00978dMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: BB16-11 f (ID# 8210)
Aptamer chemistry: DNA
Aptamer sequence: CTCCCAGGCCGTTGGGGCGTTGCCTGCGT
Target: Bifidobacterium Breve
Target chemistry: Cells
Affinity: 18.66 nM 
Reference: Hu, L., Wang, L., Lu, W., Zhai, Q., Fan, D., Liu, X., … Chen, W. (2017). Selection, identification and application of DNA aptamers for the detection of Bifidobacterium breve. RSC Advances, 7(19), 11672–11679.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: SL1111_20 (ID# 8240)
Aptamer chemistry: DNA
Aptamer sequence: GGGATACTATGCGTCCGACCGCTCGGACG
Target: RBD of SARS-COV-2 Spike protein (monomer or trimer)
Target chemistry: Protein
Affinity: 0.4-0.5 nM 
Reference: Gelinas, A. D., Tan, T. K., Liu, S., Jaramillo, J. G., Chadwick, J., Harding, A. C., Zhang, C., Ream, B. E., Chase, C. N., Otis, M. R., Lee, T., Schneider, D. J., James, W. S., & Janjic, N. (2023). Broadly neutralizing aptamers to SARS-COV-2: A diverse panel of modified DNA antiviral agents. Molecular Therapy - Nucleic Acids, 31, 370–382. https://doi.org/10.1016/j.omtn.2023.01.008Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Anti-FLAg M2 Antibody Aptamer (ABA) (ID# 7715)
Aptamer chemistry: DNA
Aptamer sequence: TCGATTTCCTTAGTTGTCTTCCTTAGTGAG
Target: Anti-FLAG M2 Antibody
Target chemistry: Protein
Affinity: 80 nM 
Reference: A Lakamp and M Ouellette. A ssDNA aptamer that blocks the function of the anti-FLAG M2 antibody. J. Nucleic Acids 2011: doi:10.4061/2011/720798Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: HIV Reverse Transcriptase (PF1) (ID# 7781)
Aptamer chemistry: DNA
Aptamer sequence: AGGAAGGCTTTAGGTCTGAGATCTCGGAAT
Target: HIV RT
Target chemistry: Protein
Affinity: 80 nM 
Reference: Y-T Lai and J DeStefano. DNA aptamers to human immunodeficiency virus reverse transcriptase selected by a primer-free SELEX method: characterization and comparison with other aptamers. Nucleic Acid Therapeutics 22(2012): 162-176.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Mitomer1 (ID# 7928)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: CACCACGAUCACGGUUUCCCUCGCAGGUAAGGUGUAGA
Target: Mitochondria
Target chemistry: Other
Affinity: . nM 
Reference: Yuri Tawaraya, Mamoru Hyodo, Mst Naznin Ara, Yuma Yamada, and Hideyoshi Harashima, ƒ??RNA Aptamers for Targeting Mitochondria Using a Mitochondria-Based SELEX Methodƒ? Biol. Pharm. Bull. 37(8) 1411-1415 (2014)Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: 1.5 M Short Anti-Heparanase Aptamer (ID# 7956)
Aptamer chemistry: DNA
Aptamer sequence: ACTTTTGAATGTGGCAACAAATTCGACAGG
Target: Heparanase
Target chemistry: Protein
Affinity: n/a nM 
Reference: Simmons SC, Jamsa H, Silva D, Cortez CM, McKenzie EA, et al. (2014) Anti-Heparanase Aptamers as Potential Diagnostic and Therapeutic Agents for Oral Cancer. PLoS ONE 9(10): e96846. doi:10.1371/journal.pone.0096846Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Insulin Binding Aptamer (IBA) (ID# 7960)
Aptamer chemistry: DNA
Aptamer sequence: GGTGGTGGGGGGGGTTGGTAGGGTGTCTTC
Target: Insulin
Target chemistry: Protein
Affinity: n/a nM 
Reference: Pu, Y.; Zhu, Z.; Han, D.; Liu, H.; Liu, J.; Liao, J.; Zhang, K.; & Tan, W. Insulin-Binding Aptamer-Conjugated Graphene Oxide for Insulin Detection. Analyst, 2011, 136, 4138-4140Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: CRP-U^gu4 (ID# 8064)
Aptamer chemistry: DNA
Aptamer sequence: CAGCGCCAAAGGCGGAAGC
Target: Human C-reactive protein (CRP)
Target chemistry: Protein
Affinity: 6.2 nM 
Reference: Minagawa H, Kataoka Y, Fujita H, Kuwahara M, Horii K, Shiratori I, Waga I. Modified DNA Aptamers for C-Reactive Protein and Lactate Dehydrogenase-5 with Sub-Nanomolar Affinities. International Journal of Molecular Sciences. 2020; 21(8):2683. https://doi.org/10.3390/ijms21082683Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.