rpgv/AptaCom huggingface dataset:
Aptamer: H63
Aptamer chemistry: ssDNA
Aptamer sequence: GTCTTGACTAGTTACGCCGGGAACAATATGTTCAAGGGCTCTTTAAAGTTTTAGTTCGTTTGTCATTCAGTTGGCGCCTC
Target: Mycobacterium tuberculosis HspX antigen
Affinity: Kd: 371 ±\u202f 0.02 nM, 371
Reference: https://pubmed.ncbi.nlm.nih.gov/30205966/
Aptamer: H63 SL-2 M6
Aptamer chemistry: ssDNA
Aptamer sequence: GTCTTGACTAGTTACGCCGGGAACAATATGTTCAAGGGCTTTTTTTTTTTTTAGTTCGTTTGTCATTCAGTTGGCGCCTC
Target: Mycobacterium tuberculosis HspX antigen
Affinity: Kd: 90 ± 2E-5 nM, 90
Reference: https://pubmed.ncbi.nlm.nih.gov/30205966/
Aptamer: M17
Aptamer chemistry: ssDNA
Aptamer sequence: TGCGGAAGCCACCAGGAGTTAGGGCCCGACGTGACGGCACGTCGGATATCTCATGCGTGTACGAGCCAAAGAGCCGCCAA
Target: Membrane proteins of matrix metalloproteinase 14 (MMP14) transfected 293T cells
Affinity: Kd: 4.98±1.26 nM, 4,98
Reference: https://pubmed.ncbi.nlm.nih.gov/31289496/
Aptamer: NA36
Aptamer chemistry: ssDNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGCCCATATGCTACTTTGCACACATCCTGGATAGGCTCCTATGCGTGCTACCGTGAA
Target: Neutrophil gelatinase-associated lipocalin (NGAL)
Affinity: Kd: 43.59 nM, 43,59
Reference: https://pubmed.ncbi.nlm.nih.gov/31215436/
Aptamer: NA42
Aptamer chemistry: ssDNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGCCGTGCGGATGTACAGGGACTTGGATAGTTTCTGACCTATGCGTGCTACCGTGAA
Target: Neutrophil gelatinase-associated lipocalin (NGAL)
Affinity: Kd: 66.55 nM, 66,55
Reference: https://pubmed.ncbi.nlm.nih.gov/31215436/
Aptamer: NA53
Aptamer chemistry: ssDNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGGCGCTGGATAGCAAGATCACGTTATCATCGTAAACCCTATGCGTGCTACCGTGAA
Target: Neutrophil gelatinase-associated lipocalin (NGAL)
Affinity: Kd: 32.52 nM, 32,52
Reference: https://pubmed.ncbi.nlm.nih.gov/31215436/
Aptamer: BI-1
Aptamer chemistry: ssDNA
Aptamer sequence: AGCGATACTGCGTGGCTGGAGGCGGGTAGGGCCAGAGTTC
Target: Beta-site amyloid precursor protein cleaving enzyme 1 (BACE-1)
Affinity: Not Mentioned in Database
Reference: https://pubmed.ncbi.nlm.nih.gov/30959405/
Aptamer: BI-2
Aptamer chemistry: ssDNA
Aptamer sequence: ATCCAGAGTGACGCAGCATTTTATCAGGGCTACAGAGGTCAGAGTTACTTAGAGCAGGTGGACACGGTGGCTTAGT
Target: Beta-site amyloid precursor protein cleaving enzyme 1 (BACE-1)
Affinity: Not Mentioned in Database
Reference: https://pubmed.ncbi.nlm.nih.gov/30959405/
Aptamer: cTX-24
Aptamer chemistry: ssDNA
Aptamer sequence: GGCAGGAAGACAAACACCCCCCCGGTTCCATCCCGTCATGATTTTCCGTAATTTGATGGTCTGTGGTGCTGT
Target: Ovarian cancer tissues (OVCAR-3, National Cancer Institute #0507709, 104 cells per test)
Affinity: Kd: 1348 ± 518.1 nM, 1348
Reference: https://pubmed.ncbi.nlm.nih.gov/30867884/
Aptamer: cTX-36
Aptamer chemistry: ssDNA
Aptamer sequence: GGCAGGAAGACAAACACACCATGTCTTGCGATGCGAAGGCCTTCTGCTCTCGCTTGTGGTCTGTGGTGCTGT
Target: Ovarian cancer tissues (OVCAR-3, National Cancer Institute #0507709, 104 cells per test)
Affinity: Kd: 129.2 ± 24.81 nM, 129,2
Reference: https://pubmed.ncbi.nlm.nih.gov/30867884/
Aptamer: cTX-45
Aptamer chemistry: ssDNA
Aptamer sequence: GGCAGGAAGACAAACACGGGGCGCCATTGAACCGATCAAGGCGGTATGGTCAGGTGTGGTCTGTGGTGCTGT
Target: Ovarian cancer tissues (OVCAR-3, National Cancer Institute #0507709, 104 cells per test)
Affinity: Kd: 178.0 ± 43.5 nM, 178
Reference: https://pubmed.ncbi.nlm.nih.gov/30867884/
Aptamer: 02rc
Aptamer chemistry: ssDNA
Aptamer sequence: GGCAGGAAGACAAACACCCCCTCGGTTCCACCCCGTCATGATTTTCCGTAATTTGATGGTCTGTGGTGCTGT
Target: Ovarian cancer tissues (OVCAR-3, National Cancer Institute #0507709, 104 cells per test)
Affinity: Kd: 2.9 ± 0.8 nM, 2,9
Reference: https://pubmed.ncbi.nlm.nih.gov/30867884/
Aptamer: H02
Aptamer chemistry: 2'-fluoro-RNA
Aptamer sequence: GGUUACCAGCCUUCACUGCGGACGGACAGAGAGUGCAACCUGCCGUGCCGCACCACGGUCGGUCACAC
Target: Integrin α5β1-expressing cells, Human & Chinese Hamster
Affinity: Kd: 72 ±11 nM for integrin α5β1, 72
Reference: https://pubmed.ncbi.nlm.nih.gov/31226519/
Aptamer: Apt03 > TH1N1
Aptamer chemistry: ssDNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGTAGGTCGTACTCTGGCGGCCTGTTTGGCCCTATCGCTGCTACCGTGAA
Target: Influenza virus subtype H1N1
Affinity: Kd: 0.082 nM, 0,082
Reference: https://pubmed.ncbi.nlm.nih.gov/31040350/
Aptamer: Apt04 > TH1N1
Aptamer chemistry: ssDNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGTGTGCGTGCTTGGGGTATAGTCGGGTCGGCCTATCGCTGCTACCGTGAA
Target: Influenza virus subtype H1N1
Affinity: Kd: 1.6 nM, 1,6
Reference: https://pubmed.ncbi.nlm.nih.gov/31040350/
Aptamer: Apt02 > TH1N1
Aptamer chemistry: ssDNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGAGGTGATGAGATTTGTACCTCTCGCGGCACCCTATCGCTGCTACCGTGAA
Target: Influenza virus subtype H1N1
Affinity: Kd: 57 nM, 57
Reference: https://pubmed.ncbi.nlm.nih.gov/31040350/
Aptamer: Apt01 > TH1N1
Aptamer chemistry: ssDNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGATTGGATCGTGACGGTTGTTGGGGCTCCGCCTATCGCTGCTACCGTGAA
Target: Influenza virus subtype H1N1
Affinity: Kd: 35000 nM, 35000
Reference: https://pubmed.ncbi.nlm.nih.gov/31040350/
Aptamer: Apt04 > TH3N2
Aptamer chemistry: ssDNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGTCTGCAGCGTGCAGGGCTGTGTGCTTACCCCCTATCGCTGCTACCGTGAA
Target: Influenza virus subtype H3N2
Affinity: Kd: 0.088 nM, 0,088
Reference: https://pubmed.ncbi.nlm.nih.gov/31040350/
Aptamer: Apt01 > TH3N2
Aptamer chemistry: ssDNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGCTAGCCGTGAGCGTGGTGAGCTCGGTTGACCCTATCGCTGCTACCGTGAA
Target: Influenza virus subtype H3N2
Affinity: Kd: 0.14 nM, 0,14
Reference: https://pubmed.ncbi.nlm.nih.gov/31040350/
Aptamer: Apt03 > TH3N2
Aptamer chemistry: ssDNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGGCGCGGGCGGTGCGTCGGTGTCCCGCTGGCCTATCGCTGCTACCGTGAA
Target: Influenza virus subtype H3N2
Affinity: Kd: 0.60 nM, 0,6
Reference: https://pubmed.ncbi.nlm.nih.gov/31040350/
Aptamer: Apt02 > TH3N2
Aptamer chemistry: ssDNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGGTGGTTGTTTTGGGCGAAGTGGCCATGGTCCCTATCGCTGCTACCGTGAA
Target: Influenza virus subtype H3N2
Affinity: Kd: 1.7 nM, 1,7
Reference: https://pubmed.ncbi.nlm.nih.gov/31040350/
Aptamer: TC-6
Aptamer chemistry: ssDNA
Aptamer sequence: ATCCATTGCCACTGACTACCTACCACCACACCACATCTCCAGCCTCAACGTCGCTTTGTCGAAGTCAGTCGGTCGTTAGT
Target: Papillary thyroid carcinoma cell line TPC-1
Affinity: Kd: 57.66 ± 5.93 nM, 56,66
Reference: https://pubmed.ncbi.nlm.nih.gov/31141341/
Aptamer: TC-6d (Truncated TC-6)
Aptamer chemistry: ssDNA
Aptamer sequence: ACTGACTACCTACCACCACACCACATCTCCAGCCTCAACGTCGCTTTGTCGAAGTCAGTC
Target: Papillary thyroid carcinoma cell line TPC-2
Affinity: Kd: 39.20 ± 8.20 nM, 39,2
Reference: https://pubmed.ncbi.nlm.nih.gov/31141341/
Aptamer: APTL-1
Aptamer chemistry: ssDNA
Aptamer sequence: CGATCAAACGTTCAAGCGGGGCCCGGAGGCGTGACTTGGACAGGCAGGCGTTACGATGCATCCCGCAAATGACGCATGA
Target: Norovirus P particles (GG2.4P), Human
Affinity: Kd: 148.13\u2009±\u20096.53\u2009nM, 148,13
Reference: https://pubmed.ncbi.nlm.nih.gov/30368291/
Aptamer: APTL-6
Aptamer chemistry: ssDNA
Aptamer sequence: CGATCAAACGTTCAAGCGGGGCCCAAGCGGCGTGGTCTGAAGTCCTGGCTGACTGCGGCGATCCCGCAAATGACGCATGA
Target: Norovirus P particles (GG2.4P), Human
Affinity: Kd: 183.30\u2009±\u200956.27\u2009nM, 183,3
Reference: https://pubmed.ncbi.nlm.nih.gov/30368291/
Aptamer: NPE-01
Aptamer chemistry: ssDNA
Aptamer sequence: ATGCGGATCCCGCGCCGGGCCACAGGGTGCGCGAAGCTTGCGC
Target: Nonylphenol ethoxylate (NPE)
Affinity: Kd: 100.9\u2009±\u200913.2\u2009nM, 100,9
Reference: https://pubmed.ncbi.nlm.nih.gov/30251354/
Aptamer: APT 1
Aptamer chemistry: ssRNA
Aptamer sequence: GGCUCGAGGAACGUACAGAGGGUGGAGAGUGGGUGGAAGCUUACGGUACCUAGC
Target: Mixed lineage leukemia protein 1 (MLL1)
Affinity: Not Mentioned in Database
Reference: https://pubmed.ncbi.nlm.nih.gov/30419633/
Aptamer: APT 2
Aptamer chemistry: ssRNA
Aptamer sequence: GGCUCGAGGACGUAACAGAGGGAGGCGAGUGGGUGGAAGCUUACGGUACCUAGC
Target: Mixed lineage leukemia protein 1 (MLL1)
Affinity: Not Mentioned in Database
Reference: https://pubmed.ncbi.nlm.nih.gov/30419633/
Aptamer: S30
Aptamer chemistry: ssDNA
Aptamer sequence: TACCAGTGCGATGCTCAGCACGCTTATAGGGGCTGGACAAAATTCTACCCAGCCTTTTCTGACGCATTCGGTTGAC
Target: CD33 antigen on leukemia cells
Affinity: Kd: 43 nM, 43
Reference: https://pubmed.ncbi.nlm.nih.gov/30519686/
Aptamer: D10
Aptamer chemistry: ssDNA
Aptamer sequence: TAGGGAAGAGAAGGACATATGATTAGGCCGTAAACGGGGCTAGGCGGGGATCATTGACTAGTACATGACCACTTGA
Target: Dickkopf-1(DKK1)
Affinity: Kd: 24.86 nM, 24,86
Reference: https://pubmed.ncbi.nlm.nih.gov/30609553/
Aptamer: C-9S
Aptamer chemistry: ssDNA
Aptamer sequence: TTATTCAATTATCGTCCGCTTTAGTGTAATGGTCCGTCCCGCAGTGAATAA
Target: Cervical cancer cells Ca Ski, Human
Affinity: Kd: 19.3\u2009±\u20092.9 nM, 19,3
Reference: https://pubmed.ncbi.nlm.nih.gov/30659315/
Aptamer: TNA1
Aptamer chemistry: ssDNA
Aptamer sequence: GTCTGAAGTAGACGCAGGAGGCTCGGGGCTCGATATTGTAAAGGGAGTGTGTTTAGGAGGACGTGGTTGGAGTCACACCTGAGTAAGCGT
Target: Trachinotus ovatus nervous necrosis virus (GTONNV)
Affinity: Kd: 27.47 nM, 27,47
Reference: https://pubmed.ncbi.nlm.nih.gov/30698517/
Aptamer: TNA4
Aptamer chemistry: ssDNA
Aptamer sequence: GTCTGAAGTAGACGCAGGAGCCTTTCGTGTTTCATTAGTGTGTTTCCATTGGGCGGCTCGGGGCAAAAGGAGTCACACCTGAGTAAGCGT
Target: Trachinotus ovatus nervous necrosis virus (GTONNV)
Affinity: Kd: 44.09 nM, 44,09
Reference: https://pubmed.ncbi.nlm.nih.gov/30698517/
Aptamer: TNA19
Aptamer chemistry: ssDNA
Aptamer sequence: GTCTGAAGTAGACGCAGGAGAACTGTATTAGCCTCTGGGTGCCGCACCGTAGTGCCCTATCTAACATCACAGTCACACCTGAGTAAGCGT
Target: Trachinotus ovatus nervous necrosis virus (GTONNV)
Affinity: Kd: 39.21 nM, 39,21
Reference: https://pubmed.ncbi.nlm.nih.gov/30698517/
Aptamer: PSA-1
Aptamer chemistry: ssDNA
Aptamer sequence: GGACGGTTGCGCTATATTTAACCAAAAGTCTGGATTAACA
Target: Prostate-specific antigen (PSA)
Affinity: Kd: 177 ± 65 nM, 177
Reference: https://pubmed.ncbi.nlm.nih.gov/30640124/
Aptamer: Ylac1
Aptamer chemistry: ssDNA
Aptamer sequence: AGGCAGGACACCGTAACCGGTGCATCTATGGCTACTAGCTTTTCCTGCCT
Target: Lactoferrin
Affinity: Kd: 2.2\u2009±\u20090.022\u2009nM, 2,2
Reference: https://pubmed.ncbi.nlm.nih.gov/30368278/
Aptamer: Ylac4
Aptamer chemistry: ssDNA
Aptamer sequence: GCAGGACACCGTAACGGGCGCACGCTCTGAATTTTGCATATGAAACAATTCTGTCCTGC
Target: Lactoferrin
Affinity: Kd: 4.0\u2009±\u20090.49\u2009nM, 4
Reference: https://pubmed.ncbi.nlm.nih.gov/30368278/
Aptamer: Ylac5
Aptamer chemistry: ssDNA
Aptamer sequence: AGGCAGGACACCGTAACGGTGCGGTCATATCCGGCTTTGCTTTTCCTGCCT
Target: Lactoferrin
Affinity: Kd: 4.7\u2009±\u20090.54\u2009nM, 4,7
Reference: https://pubmed.ncbi.nlm.nih.gov/30368278/
Aptamer: Ylac6
Aptamer chemistry: ssDNA
Aptamer sequence: GCAGGACACCGTAACGGGCGCACGCTCTGAATTTTTCATATGAAACAATTCTGTCCTGC
Target: Lactoferrin
Affinity: Kd: 1.9\u2009±\u20090.23\u2009nM, 1,9
Reference: https://pubmed.ncbi.nlm.nih.gov/30368278/
Aptamer: Ylac8
Aptamer chemistry: ssDNA
Aptamer sequence: GCAGGACACCGTAACACGGGCTTTTGCTTTATCGTACCCTTTATGCTAGATTGTCCTGC
Target: Lactoferrin
Affinity: Kd: 1.0\u2009±\u20090.12\u2009nM, 1
Reference: https://pubmed.ncbi.nlm.nih.gov/30368278/
Aptamer: Ylac9
Aptamer chemistry: ssDNA
Aptamer sequence: CAGGCAGGACACCGTAACCTTTCAGGGTGGTGCCGTTTCGGGCTTTGTCTCTTCCTGCCTG
Target: Lactoferrin
Affinity: Kd: 2.6\u2009±\u20090.34\u2009nM, 2,6
Reference: https://pubmed.ncbi.nlm.nih.gov/30368278/
Aptamer: Tr-1
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGGACGAUGCGGUCCUGUCGUCUGUUCGUCCCCAGACGACUCGCCCGA
Target: Soluble Interleukin 2 Receptor α (CD25)
Affinity: Kd: 122.0 ± 5.23 nM, 122
Reference: https://pubmed.ncbi.nlm.nih.gov/31383650/
Aptamer: Tr-6
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGGACGAUGCGGCGUUUCCUCUGGUUCGUCCCCAGACGACUCGCCCGA
Target: Soluble Interleukin 2 Receptor α (CD25)
Affinity: Kd: 96.9 ± 5.77 nM, 96,9
Reference: https://pubmed.ncbi.nlm.nih.gov/31383650/
Aptamer: Tr-7
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGGACGAUGCGGUGAGUCGUUCCCUUCGUCCCCAGACGACUCGCCCGA
Target: Soluble Interleukin 2 Receptor α (CD25)
Affinity: Kd: 68.2 ± 2.73 nM, 68,2
Reference: https://pubmed.ncbi.nlm.nih.gov/31383650/
Aptamer: Tr-8
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGGACGAUGCGGGCCGUUGUUGUGUGCCGCCCCAGACGACUCGCCCGA
Target: Soluble Interleukin 2 Receptor α (CD25)
Affinity: Kd: 35.7 ± 1.56 nM, 35,7
Reference: https://pubmed.ncbi.nlm.nih.gov/31383650/
Aptamer: Tr-11
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGGACGAUGCGGAUUCUGGUUACUGGCCGCCCCAGACGACUCGCCCGA
Target: Soluble Interleukin 2 Receptor α (CD25)
Affinity: Kd: 46.1 ± 1.76 nM, 46,1
Reference: https://pubmed.ncbi.nlm.nih.gov/31383650/
Aptamer: MS10
Aptamer chemistry: ssDNA
Aptamer sequence: GTCTTGACTAGTTACGCCGGTGTGTTGACTGAGGGGGTGGGGTGGGTGGTGGTGGATATAGCTCATTCAGTTGGCGCCTC
Target: Mycobacterium tuberculosis (Mtb) Malate synthaseMS
Affinity: Kd: 12 nM, 12
Reference: https://pubmed.ncbi.nlm.nih.gov/31704587/
Aptamer: EPCAM-APT-01
Aptamer chemistry: ssDNA
Aptamer sequence: CTCCTCTGACTGTAACCACGACACGCACAAATGTCAGTGTACCGCACTCGCACATTCTTAGCATAGGTAGTCCAGAAGCC
Target: Epithelial cell adhesion molecule (EpCAM)
Affinity: Kd: 25 nM, 25
Reference: https://pubmed.ncbi.nlm.nih.gov/30871104/
Aptamer: EPCAM-APT-02
Aptamer chemistry: ssDNA
Aptamer sequence: CTCCTCTGACTGTAACCACGGTGCGCGTACCACCATGTGTACACACTGCATGTTTGGTTAGCATAGGTAGTCCAGAAGCC
Target: Epithelial cell adhesion molecule (EpCAM)
Affinity: Kd: 15 nM, 15
Reference: https://pubmed.ncbi.nlm.nih.gov/30871104/
Aptamer: Az9
Aptamer chemistry: ssDNA
Aptamer sequence: ATACCAGCTTATTCAATTCAGGAAGACAACTCCGACTAGAATTGATAATCAAGAATTCGTCTGGGGGGAATGTGCGAGATAGTAAGTGCAATCT
Target: Azlocillin
Affinity: Kd: 55 nM, 55
Reference: https://pubmed.ncbi.nlm.nih.gov/32029106/
Aptamer: aptamer 31
Aptamer chemistry: ssDNA
Aptamer sequence: ATTGGCACTCCACGCATAGGACGCATAGGGTGCGACCACATACGCCCCATGTATGTCCCTTGGTTGTGCCCTATGCGTCCTATGCGTGCTACCGTGAA
Target: Di(2-ethylhexyl) phthalate (DEHP)
Affinity: Kd: 2.26 ± 0.06 nM, 2,26
Reference: https://pubmed.ncbi.nlm.nih.gov/32050451/
Aptamer: T1–T4 dimer
Aptamer chemistry: ssDNA
Aptamer sequence: GCTGTGTGACTCCTGCAATCCGATCGGTATATCCGTCGGATTTTTTTTTTGGTCACTGCATGTGACCGCAGCTGTATCTTGTCTCC
Target: Anti-human tumor necrosis factor alpha (anti‐hTNF‐α)
Affinity: Kd: 67nM, 67
Reference: https://pubmed.ncbi.nlm.nih.gov/31989789/
Aptamer: aptamer 1
Aptamer chemistry: ssDNA
Aptamer sequence: TCCCACGCATTCTCCACATCCAGGGCGCTACGGTATGTGTTGGGTCTGGCGTAGGGCTGGCTTTCTGTCCTTCCGTCACAA
Target: Crystalline hydroxyapatite (Ca10(PO4)6(OH)2; HAP)
Affinity: Ka: 3.0 + 0.9 × 10^6 M−1, nan
Reference: https://pubmed.ncbi.nlm.nih.gov/32278386/
Aptamer: EP23
Aptamer chemistry: 2'-fluoro-RNA
Aptamer sequence: ACGUAUCCCUUUUCGCGUA
Target: Epithelial cellular adhesion molecule (EpCAM)
Affinity: Kd: 39.89 ± 3.37 nM, 39,89
Reference: https://pubmed.ncbi.nlm.nih.gov/32234785/
Aptamer: A5U
Aptamer chemistry: 2'-fluoro-RNA
Aptamer sequence: ACGUUUCCCUUUUCGCGUA
Target: Epithelial cellular adhesion molecule (EpCAM)
Affinity: Kd: 10.78 ± 1.37 nM, 10,78
Reference: https://pubmed.ncbi.nlm.nih.gov/32234785/
Aptamer: G15U
Aptamer chemistry: 2'-fluoro-RNA
Aptamer sequence: ACGUAUCCCUUUUCUCGUA
Target: Epithelial cellular adhesion molecule (EpCAM)
Affinity: Kd: 11.91 ± 0.95 nM, 11,91
Reference: https://pubmed.ncbi.nlm.nih.gov/32234785/
Aptamer: CRP–Ugu4-3
Aptamer chemistry: 5-uracil-modified-DNA
Aptamer sequence: GATATGTCCAGCCTGTCGAATGCCtAGttCtGCCttAAtAtGGtCGGttAAGCCTAAACTGATGTGCGGCGTAACC
Target: C-reactive protein (CRP). Human
Affinity: Kd: 6.2 pM, 0,0062
Reference: https://pubmed.ncbi.nlm.nih.gov/32294882/
Aptamer: LDH-Aad1-−3
Aptamer chemistry: 5-uracil-modified-DNA
Aptamer sequence: GTATAGTAGCCAGCCAGCCTTAGGCTGCTGGCTCGTGaGaCGGaTaTCaGGTCTCATAAACGGCGAGGTGTCAATTCC
Target: Lactate dehydrogenase-5 (LDH-5), Human
Affinity: Kd: 235 pM, 0,235
Reference: https://pubmed.ncbi.nlm.nih.gov/32294882/
Aptamer: TN2
Aptamer chemistry: ssRNA
Aptamer sequence: UAGGGAAGAGAAGGACAUAUGAUAAGGCCGACGUAAUGUGUCGGUCGUUACGCGUCGUGCACGUUGACUAGUACAUGACCACUUGA
Target: Triple-negative breast cancer (TNBC) cell line MDA-MB-231
Affinity: Kd: 59.12 ± 12.93 by streptavidin-biotin colorimetric assay and 73.02 ± 12 by flow cytometric assay, 59,12
Reference: https://pubmed.ncbi.nlm.nih.gov/32222697/
Aptamer: TN3
Aptamer chemistry: ssRNA
Aptamer sequence: UAGGGAAGAGAAGGACAUAUGAUCCGAUCUCACGCGCACCUUCUCUUCAGCGCGCGACUGGCAUUGACUAGUACAUGACCACUUGA
Target: Triple-negative breast cancer (TNBC) cell line MDA-MB-232
Affinity: Kd: 21.91 ± 3.08 by streptavidin-biotin colorimetric assay and 28.93 ± 9.72 by flow cytometric assay, 21,91
Reference: https://pubmed.ncbi.nlm.nih.gov/32222697/
Aptamer: TN20
Aptamer chemistry: ssRNA
Aptamer sequence: UAGGGAAGAGAAGGACAUAUGAUCGAUGCGCACCGAUCUCUCUUCUGCACGUCCUUCGGCACAUUGACUAGUACAUGACCACUUGA
Target: Triple-negative breast cancer (TNBC) cell line MDA-MB-233
Affinity: Kd: 24.30 ± 4.99 by streptavidin-biotin colorimetric assay and 23.92 ± 3.59 by flow cytometric assay, 24,3
Reference: https://pubmed.ncbi.nlm.nih.gov/32222697/
Aptamer: TN29
Aptamer chemistry: ssRNA
Aptamer sequence: UAGGGAAGAGAAGGACAUAUGAUCCUGCCCCAACCAUCGCUUCCUCGACGCGCGUUGUCGGCAUUGACUAGUACAUGACCACUUGA
Target: Triple-negative breast cancer (TNBC) cell line MDA-MB-234
Affinity: Kd: 9.84 ± 1.63 by streptavidin-biotin colorimetric assay and 10.77 ± 2.41 by flow cytometric assay, 9,84
Reference: https://pubmed.ncbi.nlm.nih.gov/32222697/
Aptamer: TN58
Aptamer chemistry: ssRNA
Aptamer sequence: UAGGGAAGAGAAGGACAUAUGAUGCAACGUUGUGGUCCCGUUUGCACUUUGUUUACGCGCGCAUUGACUAGUACAUGACCACUUGA
Target: Triple-negative breast cancer (TNBC) cell line MDA-MB-235
Affinity: Kd: 17.17 ± 2.87 by streptavidin-biotin colorimetric assay and 26.09 ± 3.20 by flow cytometric assay, 17,17
Reference: https://pubmed.ncbi.nlm.nih.gov/32222697/
Aptamer: TN145
Aptamer chemistry: ssRNA
Aptamer sequence: UAGGGAAGAGAAGGACAUAUGAUCCUCAGCGCGCAACUUCCCUCCGUUCCCUGCCACGCGUCA
Target: Triple-negative breast cancer (TNBC) cell line MDA-MB-236
Affinity: Kd: 26.88 ± 3.68 streptavidin-biotin colorimetric assay and 37.36 ± 3.50 by flow cytometric assay, 26,88
Reference: https://pubmed.ncbi.nlm.nih.gov/32222697/
Aptamer: DUX4 aptamer
Aptamer chemistry: ssRNA
Aptamer sequence: AUCCAGAGUGACGCAGCUAACUUAAUCAACCGCAGGUUGAUUAGCCCAUUAGCUGGACACGGUGGCUUAGU
Target: Double homeobox protein 4 (DUX4)
Affinity: Kd: 20 nM, 20
Reference: https://pubmed.ncbi.nlm.nih.gov/32020675/
Aptamer: aptamer-X35
Aptamer chemistry: ssDNA
Aptamer sequence: ATGACCATGACCCTCCACACTGTAGGCACCACGGGTCCCTGGCAGTTAAAAGTACGTTTGTCAGACTGTGGCAGGGAAACA
Target: Mas-related G-protein coupled receptor X2 (MRGPRX2)
Affinity: Not Mentioned in Database
Reference: https://pubmed.ncbi.nlm.nih.gov/32320700/
Aptamer: DDT_13
Aptamer chemistry: ssDNA
Aptamer sequence: TCCAGCACTCCACGCATAACGAATTGTGCTCAATGCGCCCCTGCAGTGAATGTGGAATTTGTTATGCGTGCGACGGTGAA
Target: 1,1,1-trichloro-2-(p-chlorophenyl)-2-(o-chlorophenyl) ethane (O,p'-DDT)
Affinity: Kd: 412.3 ± 124.6 nM, 412,3
Reference: https://pubmed.ncbi.nlm.nih.gov/32210057/
Aptamer: Apt17
Aptamer chemistry: ssDNA
Aptamer sequence: TAGGGAAGAGAAGGACATATGATGCAATGGAACCGCTGAACGACCCTAGCATTATCAGTGTGGTTGACTAGTACATGACCACTTGA
Target: SipA effector protein secreted by type three secretory system (T3SS)
Affinity: Kd: 114.9 nM at 27 °C and 63.4 nM at 37 °C, 114,9
Reference: https://pubmed.ncbi.nlm.nih.gov/31953175/
Aptamer: Apt122
Aptamer chemistry: ssDNA
Aptamer sequence: GCTGTGTGACTCCTGCAAACTACTGGTGTTCCTTGCCCTGTTTCAATAAATCGTGTGTGCCGCAGCTGTATCTTGTCTCC
Target: Tacrolimus (TAC)
Affinity: Kd: 56.45 nM, 56,45
Reference: https://pubmed.ncbi.nlm.nih.gov/31499431/
Aptamer: RNV-L7
Aptamer chemistry: ssDNA
Aptamer sequence: GGACAGGACCACACCCAGCGCGGTCGGCGGGTGGGCGGGGGGAGAACGAGGTAGGGGTCAGGCTCCTGTGTGTCGCTTTGT
Target: Mammalian cell-expressed human recombinant low-density lipoprotein receptor (LDL-R) protein
Affinity: Kd: 19.6 nM, 19,6
Reference: https://pubmed.ncbi.nlm.nih.gov/31841991/
Aptamer: caDNApt-1
Aptamer chemistry: ssDNA
Aptamer sequence: ATACCAGCTTATTCAATTATTCAATTCGAGGCGGGTGGGTGGGTTGAATGATAGTAAGTGCAATCT
Target: Cyclic adenosine monophosphate (cAMP)
Affinity: Kd: 1 mM, 1000000
Reference: https://pubmed.ncbi.nlm.nih.gov/31099939/
Aptamer: CD63-1
Aptamer chemistry: ssDNA
Aptamer sequence: TAACACGACAGACGTTCGGAGGTCGAACCCTGACAGCGTGGG
Target: CD63 protein
Affinity: Kd: 38.71 ± 6.22 nM via ELISA assay, 38,71
Reference: https://pubmed.ncbi.nlm.nih.gov/33261145/
Aptamer: CD63-1
Aptamer chemistry: ssDNA
Aptamer sequence: TAACACGACAGACGTTCGGAGGTCGAACCCTGACAGCGTGGG
Target: CD63 positive cells, including breast cancer MDA-MB-231 cells and CD63-overexpressed HEK293T cells
Affinity: Kd: 96.92 nM and 113.20 nM for MDA-MB-231 and HEK293T/CD63 cells respectively via flow cytometry, 96,92
Reference: https://pubmed.ncbi.nlm.nih.gov/33261145/
Aptamer: XQ-P3
Aptamer chemistry: ssDNA
Aptamer sequence: ACCGACCGTGCTGGACTCATCTCGCTTTTTTCACGGTCCACACTACTATGAGCGAGCCTGGCG
Target: PD-L1 (MDA-MB-231 PD-L1 OE cells), Human
Affinity: Kd: 15 ± 1.74 nM, 15
Reference: https://pubmed.ncbi.nlm.nih.gov/32574155/
Aptamer: E22P–AbD43
Aptamer chemistry: ssRNA
Aptamer sequence: GGGACGAAGACCAACUGAACUUUGUGGUGGCGGCUACUCGUGUUCUUUUGACUUUGUCCGUGCUGCCACCUUACUUC
Target: Toxic beta-amyloid 42 dimer (Aβ42)
Affinity: Kd: 20 ± 6.0 nM, 20
Reference: https://pubmed.ncbi.nlm.nih.gov/32127399/
Aptamer: GABAS-01
Aptamer chemistry: ssDNA
Aptamer sequence: ATGCGGATCCCGCGCGCAGTGCAGGGAGCCGCTCCACGTACGTTGCGCGAAGCTTGCGC
Target: Glycated Human Serum Albumin (GHSA)
Affinity: Kd: 1.748 ± 0.227 nM, 1,748
Reference: https://pubmed.ncbi.nlm.nih.gov/33066521
Aptamer: C7
Aptamer chemistry: ssDNA
Aptamer sequence: GGCCATTGTGGACTTCTTTGGGTAATTCAGGGGCTCGATT
Target: Rituximab, anti-CD20 lgG1 antibody
Affinity: Kd: 8.8nM, 8,8
Reference: https://pubmed.ncbi.nlm.nih.gov/33151990/
Aptamer: C2
Aptamer chemistry: ssDNA
Aptamer sequence: ATACCAGCTTATTCAATTTAGTATTCACGGCAGAGTCTGGCAGACTTGTCTTCTTGTGAGATAGTAAGTGCAATCT
Target: Rituximab, anti-CD20 lgG1antibody
Affinity: Kd: 65.8 nM, 65,8
Reference: https://pubmed.ncbi.nlm.nih.gov/33151990/
Aptamer: C4
Aptamer chemistry: ssDNA
Aptamer sequence: ATACCAGCTTATTCAATTGGACTTGTTTGCTCGAACGATGGTTTGTGCTTTTGTGTTAGATAGTAAGTGCAATCT
Target: Rituximab, anti-CD20 lgG1 antibody
Affinity: Kd: 86.7 nM, 86,7
Reference: https://pubmed.ncbi.nlm.nih.gov/33151990/
Aptamer: C5
Aptamer chemistry: ssDNA
Aptamer sequence: ATACCAGCTTATTCAATTCGCTCCGTTTACTCGGTCTGCTATTGGCTTGCCTTTGTTTAGATAGTAAGTGCAATCT
Target: Rituximab, anti-CD20 lgG1 antibody
Affinity: Kd: 56.5 nM, 56,5
Reference: https://pubmed.ncbi.nlm.nih.gov/33151990/
Aptamer: C10
Aptamer chemistry: ssDNA
Aptamer sequence: ACTTCGGCTAGTTAGGGGGTAGTTTAGATCGTCTCTACAT
Target: Rituximab, anti-CD20 lgG1 antibody
Affinity: Kd: 17.6 nM, 17,6
Reference: https://pubmed.ncbi.nlm.nih.gov/33151990/
Aptamer: C57
Aptamer chemistry: ssDNA
Aptamer sequence: ATACCAGCTTATTCAATTGGCGTATGCAGTTTTGTAGGGTTATCAAGGCTTGACGATTAGATAGTAAGTGCAATCT
Target: Rituximab, anti-CD20 lgG1 antibody
Affinity: Kd: 82.4 nM, 82,4
Reference: https://pubmed.ncbi.nlm.nih.gov/33151990/
Aptamer: Cm-4
Aptamer chemistry: ssDNA
Aptamer sequence: ATACCAGCTTATTCAATTAAGCGGGGTTGAGATATATTAACTAGACAACTTGTTAAAACTCGCGACTACAGATAGTAAGTGCAATCT
Target: Hepatitis B surface antigen (HBsAg)
Affinity: Kd:\u2009148.41\u2009±\u20091.5 nM via flow cytometry analysis, 148,41
Reference: https://pubmed.ncbi.nlm.nih.gov/33400073/
Aptamer: XK-10
Aptamer chemistry: ssDNA
Aptamer sequence: GACAGGCAGGACACCGTAACGGCAGGACACCGTAACGGGTATGCAGCTATCCCGGGCGCTGTCTGAAGATCGTGTGCTGCTCTGCTACCTCCCTCCTCTTC
Target: Klebsiella Pneumoniae Carbapenemase 2 (KPC-2) specifically on KPC-2 Escherichia coli (E. coli)
Affinity: Kd: 0.81 ± 0.13 nM via SPR & 12.9 ± 1.03 nM via microarray chip , 0,81
Reference: https://pubmed.ncbi.nlm.nih.gov/33379005/
Aptamer: OC2
Aptamer chemistry: ssDNA
Aptamer sequence: ATACCAGCTTATTCAATTGGCGATGAGAACGGGAGCCTGATGATACACACGAGCGATCGCTCATAAAAGCCGTGCCCGAGATAGTAAGTGCAATCT
Target: Osteocalcin (OC) - osteoporosis biomarker
Affinity: Kd: 55.5 nM via fluorescence-based assay, 55,5
Reference: https://pubmed.ncbi.nlm.nih.gov/33379043/
Aptamer: BC1
Aptamer chemistry: ssDNA
Aptamer sequence: ATGACGGGGGTCTAGGCAAGTAATAACGGGGGCAAGCTTTTCTATCTCGTTCTAGGGTA
Target: Beta-crosslap (BC) - osteoporosis biomarker
Affinity: Kd: 69.34 nM via fluorescence-based assay, 69,34
Reference: https://pubmed.ncbi.nlm.nih.gov/33379043/
Aptamer: T-2
Aptamer chemistry: ssDNA
Aptamer sequence: CCTAACCGATATCACACTCACCGCGTGAGCGGGGAGGCGATGCCCAGGCTAACTTGACTCAGTTGGTCGTCATTGGAGTATC
Target: Thyroglobulin (Tg)
Affinity: Kd: 3.18 μM via sequence homology using Clustal X software & 4.51 nM via TFI assay, 3,18
Reference: https://pubmed.ncbi.nlm.nih.gov/33303143/
Aptamer: ARH1t6
Aptamer chemistry: ssDNA
Aptamer sequence: TTACGTCAAGGTGTCACTCCGCCAGGTGTGCGACGGTCGT
Target: RNase H2 from Clostridium difficile (C. difficile) (CDH2)
Affinity: Kd: 1.8 ± 0.5 nM & inhibition constant (IC50) of 7.1 ± 0.6 nM, 1,8
Reference: https://pubmed.ncbi.nlm.nih.gov/33410654/