rpgv/AptaCom huggingface dataset:
Aptamer: TD05.17 (ID# 8051)
Aptamer chemistry: DNA
Aptamer sequence: AGGAGGATAGTTCGGTGGCTGTTCAGGGTCTCCTCCT
Target: B-cells
Target chemistry: Cells
Affinity: 43 nM 
Reference: Mallikaratchy, P. R., Ruggiero, A., Gardner, J. R., Kuryavyi, V., Maguire, W. F., Heaney, M. L., McDevitt, M. R., Patel, D. J., & Scheinberg, D. A. (2011). A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia. Nucleic acids research, 39(6), 2458–2469. https://doi.org/10.1093/nar/gkq996Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: G12msi (ID# 8073)
Aptamer chemistry: DNA
Aptamer sequence: GTGAATTGCGTTGAATTATGTTTCAGTCATCACT
Target: GPC3
Target chemistry: Protein
Affinity: 0.17 nM 
Reference: Park, J. Y., Chae, J. R., Cho, Y. L., Kim, Y., Lee, D., Lee, J. K., & Kang, W. J. (2020). Targeted Therapy of Hepatocellular Carcinoma Using Gemcitabine-Incorporated GPC3 Aptamer. Pharmaceutics, 12(10), 985. doi:10.3390/pharmaceutics12100985Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: TAFapt1-S (ID# 8078)
Aptamer chemistry: RNA
Aptamer sequence: GGGUUUUCGGGAUACGCGGAGGGUGGGCAAUAACCCC
Target: AML1-MTG8
Target chemistry: Protein
Affinity: 4.47 nM 
Reference: Fukunaga, Junichi et al. “A G-quadruplex-forming RNA aptamer binds to the MTG8 TAFH domain and dissociates the leukemic AML1-MTG8 fusion protein from DNA.” FEBS letters vol. 594,21 (2020): 3477-3489. doi:10.1002/1873-3468.13914Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: KM41 (ID# 8219)
Aptamer chemistry: RNA
Aptamer sequence: UAAUACGACUCACUAUAGGGAAUUCGAGCUCGGUACC
Target: A-beta40
Target chemistry: Protein
Affinity: Not Mentioned in Database
Reference: Rahimi F, Murakami K, Summers JL, Chen C-HB, Bitan G (2009) RNA Aptamers Generated against Oligomeric Ab40 Recognize Common Amyloid Aptatopes with Low Specificity but High Sensitivity. PLoS ONE 4(11): e7694.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Malachite Green (MG-4) (ID# 7481)
Aptamer chemistry: RNA
Aptamer sequence: GGAUCCCGACUGGCGAGAGCCAGGUAACGAAUGGAUCC
Target: Malchite Green
Target chemistry: Small Organic
Affinity: 1 µM 
Reference: Grate, Dilara and Wilson, Charles. "Laser-mediated, site-specific inactivation of RNA transcripts." PNAS, 96 (1999): 6131-6136Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Theophylline (mTCT8-4) (ID# 7551)
Aptamer chemistry: RNA
Aptamer sequence: AGUGAUACCAGCAUCGUCUUGAUGCCCUUGGCAGCACU
Target: Theophylline
Target chemistry: Small Organic
Affinity: 100 nM 
Reference: Jenison et al. "High-resolution molecular discrimination by RNA." Science, 263(1994): 1425-1429.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: PCB77 (II) (ID# 7689)
Aptamer chemistry: DNA
Aptamer sequence: AAGCGCGCGAGACTACGTTTGTAGGGATACCGATGTCG
Target: 3,3,4,4-tetrachlorobiphenyl (PCB77)
Target chemistry: Small Organic
Affinity: 8.32 µM 
Reference: Shengmin, X. (2012). Selection of dna aptamers against polychlorinated biphenyls as potential biorecognition elements for environmental analysis. Analytical Biochemistry, 423(2012), 195-201.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Plasmodium vivax lactate dehydrogenase  (pL2) (ID# 7695)
Aptamer chemistry: DNA
Aptamer sequence: GAACTCATTGGCTGGAGGCGGCAGTACCGCTTGAGTTC
Target: Plasmodium vivax lactate dehydrogenase  (PvLDH)
Target chemistry: Protein
Affinity: 31.7 nM 
Reference: Seonghwan, L. (2012). A highly sensitive aptasensor towards plasmodium lactate dehydrogenase for the diagnosis of malaria. Biosensors and Bioelectronics, 35(2012), 291-296.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Plasmodium falciparum lactate dehydrogenase  (pL2) (ID# 7696)
Aptamer chemistry: DNA
Aptamer sequence: GAACTCATTGGCTGGAGGCGGCAGTACCGCTTGAGTTC
Target: Plasmodium falciparum lactate dehydrogenase  (PfLDH)
Target chemistry: Protein
Affinity: 49.6 nM 
Reference: Seonghwan, L. (2012). A highly sensitive aptasensor towards plasmodium lactate dehydrogenase for the diagnosis of malaria. Biosensors and Bioelectronics, 35(2012), 291-296.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: C5a (C5C6) (ID# 7718)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: CGAUGCGGUCUCAUGCGUCGAGUGUGAGUUUACCUUCG
Target: Human complement C5 component (C5a)
Target chemistry: Protein
Affinity: Not Mentioned in Database
Reference: G Biesecker et al.. "Derivation of RNA aptamer inhibitors of human complement C5." Immunopharmacology 42(1999):219-230Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Cocaine (MNS-4.1) (ID# 7783)
Aptamer chemistry: DNA
Aptamer sequence: GGGAGACAAGGAAAATCCTTCAATGAAGTGGGTCGACA
Target: Cocaine
Target chemistry: Small Organic
Affinity: 0.4 µM 
Reference: M Stojanovic, P de Prada, and D Landry. Aptamer-based folding fluorescent sensor for cocaine. J. Am. Chem. Soc. 123(2001): 4928-4931.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Tyrosine-Cp*Rh(III) sensor (ID# 8049)
Aptamer chemistry: DNA
Aptamer sequence: CTCTCGGGACGACGGCCCGATCTCAGAGTAGTCGTCCC
Target: Tyrosine
Target chemistry: Small Organic
Affinity: 2.9 nM 
Reference: Yang KA, Barbu M, Halim M, et al. Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors. Nat Chem. 2014;6(11):1003-1008. doi:10.1038/nchem.2058Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: TTA1.2 (ID# 8052)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGGAGGACGCGUCGCCGUAAUGGAUGUUUUGCUCCCUG
Target: Tenascin-C (TN-C)
Target chemistry: Protein
Affinity: 2.4 nM 
Reference: Schmidt KS, Borkowski S, Kurreck J, Stephens AW,Bald R, Hecht M, et al. Application of locked nucleicacids to improve aptamer in vivo stability and targeting function. Nucleic Acids Res 2004; 32:5757-65; PMID:15509871; http://dx.doi.org/10.1093/nar/gkh862Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: R3(2) – truncated (ID# 8205)
Aptamer chemistry: DNA
Aptamer sequence: CGCCCGTGTTTATCCGTTTGCTCTTAGTGGCACGGGGG
Target: immunoglobulin E
Target chemistry: Antibody
Affinity: 22.6 nM 
Reference: Bai, cheng, et al." Surface acoustic wave‑assisted microfluidic isolation of aptamers." Microfluidics and Nanofluidics, 26(2002): 1-10Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: RNase H1 (VI-2) (ID# 7521)
Aptamer chemistry: DNA
Aptamer sequence: CGGTCGCTCCGTGTGGCTTGGGTTGGGTGTGGCAGTGAC
Target: RNase H1
Target chemistry: Protein
Affinity: 11 nM 
Reference: Pileur, et al. "Selective inhibitory DNA aptamers of the human RNase H1." Nucleic Acids Research, 31 (2003): 5776-5788.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Apple Stem Pitting Virus of PSAH PearIsolate (ID# 7561)
Aptamer chemistry: DNA
Aptamer sequence: AGCAAGGTTTGGTGTTGGTTGGTTGCTGGTTTTGGTTTC
Target: Apple Stem Pitting Virus (ASPV)
Target chemistry: Protein
Affinity: 8 nM 
Reference: Balogh, et al. "Selection and versatile application of virus-specific aptamers." FASEB Journal, 24(2010): 4187-4195.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: EGFR (CL4) (ID# 7811)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GCCUUAGUAACGUGCUUUGAUGUCGAUUCGACAGGAGGC
Target: EGFR - Extracellular Domain
Target chemistry: Protein
Affinity: 10 nM 
Reference: CL Esposito et al. A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death. PLoS One  6(2011):e24071.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Z23 Anti-Vesicular Stomatitis Virus (ID# 7958)
Aptamer chemistry: DNA
Aptamer sequence: GGGACCTATCAGGCGATGTGAAAACTCTTATACCACTGG
Target: Vesicular Stomatitis Virus
Target chemistry: Other
Affinity: EC50 =/< 80 nM 
Reference: Muharemagic D, Zamay A, Ghobadloo SM, Evgin L, Savitskaya A, et al. (2014) Aptamer-Facilitated Protection of Oncolytic Virus from Neutralizing Antibodies. Molecular Therapy--Nucleic Acids 3, e167. doi: 10.1038/mtna.2014.19Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: DOX 6 (ID# 8012)
Aptamer chemistry: DNA
Aptamer sequence: GGGCGAGAACAGTGTCCCAGTCGCTAGTTTTCTCTGCCC
Target: Doxycycline
Target chemistry: Small Organic
Affinity: 150 nM 
Reference: Lee, K.H., Zeng, H. A general double library SELEX strategy for aptamer selection using unmodified nonimmobilized targets. Anal Bioanal Chem 409, 5081–5089 (2017).Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: AptHis-C (ID# 8132)
Aptamer chemistry: DNA
Aptamer sequence: TGGCAAGAGGGTGTGCTTAAGGTGGACACGGTGGCTTAG
Target: Hexahistidine
Target chemistry: Small Organic
Affinity: 20.8 nM 
Reference: Wu, S.; Liu, Y.; Sun, H.; Zhong, M.; Dai, B.; Pan, B.; Shen, Z. An ssDNA aptamer specific for detection and purification of hexahistidine-tagged proteins. Anal. Biochem. 2020 Oct 15; 607: 113893. DOI: 10.1016/j.ab.2020.113893.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: 39SGP1A (ID# 8151)
Aptamer chemistry: RNA
Aptamer sequence: GGGCGCUCAAUUUUUUAUUGCAUUUUUCUUUGAGCGCCC
Target: Ebola virus Soluble glycoprotein (sGP)
Target chemistry: Protein
Affinity: 30 nM 
Reference: Shubham, S., Hoinka, J., Banerjee, S. et al. A 2′FY-RNA Motif Defines an Aptamer for Ebolavirus Secreted Protein. Sci Rep 8, 12373 (2018). https://doi.org/10.1038/s41598-018-30590-8Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Crimean-Congo Hemorrhagic fever (ID# 8245)
Aptamer chemistry: RNA
Aptamer sequence: CCGTAGGGTTAGGGGCGGATCGTCAGGGTGGATAAGGCA
Target: Nucleoprotein (NP)
Target chemistry: Protein
Affinity: 6.62x10^-10 nM 
Reference: Jalali, T., Salehi-Vaziri, M., Pouriayevali, M. H., & Gargari, S. L. M. (2021). Aptamer based diagnosis of crimean-congo hemorrhagic fever from clinical specimens. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-91826-8Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: ATP (ATP-40-1) (ID# 7508)
Aptamer chemistry: RNA
Aptamer sequence: GGGUUGGGAAGAAACUGUGGCACUUCGGUGCCAGCAACCC
Target: ATP
Target chemistry: Small Organic
Affinity: 700 nM 
Reference: sassanfar and Szostak. "An RNA motif that binds ATP."Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: L-Histidine (His 945) (ID# 7520)
Aptamer chemistry: RNA
Aptamer sequence: GGCAUCGGAAAGUGGGUUGAUGUAAGUAACAGGCGAUGCC
Target: L-Histidine
Target chemistry: Small Organic
Affinity: 12 µM 
Reference: Majerfeld, et al. "RNA Affnity for Molecular L-Histidine; Genetic Code Origins." Journal of Molecular Evolution, 61 (2005): 226-235.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: HIV-1 Nuceocapsid (ID# 7537)
Aptamer chemistry: RNA
Aptamer sequence: GGAGACAUCCCUCUUGUUGGUGGUGCCGUGUGGAUGUCUC
Target: HIV-1 Nuceocapsid
Target chemistry: Protein
Affinity: 2.3 nM 
Reference: Berglund, A., et al. "A High Affinity Binding Site for the HIV-1 Nucleocapsid Protein." Nucleic Acids Research, 25(1997):1042-1049.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Platelet-Derived Growth Factor (PDGF) B-chain (36t) (ID# 7545)
Aptamer chemistry: DNA
Aptamer sequence: CACAGGCTACGGCACGTAGAGCATCACCATGATCCTGTGT
Target: Platelet-Derived Growth Factor -AB (PDGF-AB)
Target chemistry: Protein
Affinity: 0.094 nM 
Reference: Green, L., et al. "Inhibitory DNA Ligands to Platelet-Derived Growth Factor B-Chain." Journal of Biochemistry, 35(1996): 14413-14424.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: MT32 protein of Apple Stem Pitting Virus (ASPV) (ID# 7560)
Aptamer chemistry: DNA
Aptamer sequence: GGGGTGGTGGGTTCTTTTTGTGGTATTGGTGTGGGGGGCA
Target: MT32 coat protein
Target chemistry: Protein
Affinity: 55 nM 
Reference: Balogh, et al. "Selection and versatile application of virus-specific aptamers." FASEB Journal, 24(2010): 4187-4195.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Anti-His Tag (6H7) (ID# 7564)
Aptamer chemistry: DNA
Aptamer sequence: GCTATGGGTGGTCTGGTTGGGATTGGCCCCGGGAGCTGGC
Target: 6X His Tag
Target chemistry: Protein
Affinity: 4.6 nM 
Reference: Kokpinar, et al. "Aptamer-Based Downstream Processing of His-Tagged Proteins Utilizing Magnetic Beads." Biotechnology and Bioengineering, 108(2011):2371-2379.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Phospholamban (Apt-9) (ID# 7584)
Aptamer chemistry: DNA
Aptamer sequence: TTGGGGAGGGGCACTGGGCAGTGTAATTTACGAAAGCGAG
Target: Phospholamban
Target chemistry: Protein
Affinity: 20 nM 
Reference: Tanaka et al. "In Vitro Selection and Characterization of DNA Aptamers Specific for Phospholamban." The Journal of Pharmacology and Experimental Therapeutics, 329(2009): 57-63.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: PCB77 (VIII) (ID# 7690)
Aptamer chemistry: DNA
Aptamer sequence: GGCGGGGCTACGAAGTAGTGATTTTTTCCGATGGCCCGTG
Target: 3,3,4,4-tetrachlorobiphenyl (PCB77)
Target chemistry: Small Organic
Affinity: 4.02 µM 
Reference: Shengmin, X. (2012). Selection of dna aptamers against polychlorinated biphenyls as potential biorecognition elements for environmental analysis. Analytical Biochemistry, 423(2012), 195-201.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: a-Bungarotoxin (Clone 24) (ID# 7729)
Aptamer chemistry: DNA
Aptamer sequence: GCGAGGTGTTCGAGAGTTAGGGGCGACATGACCAAACGTT
Target: a-Bungarotoxin
Target chemistry: Protein
Affinity: 7.5 µM 
Reference: L H Lauridsen. Rapid one-step selection method for generating nucleic acid aptamers: development of a DNA aptamer against a-bungarotoxin. PLoS ONE 7(2012): e41702.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Osteopontin (OPN-R3) (ID# 7736)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: CGGCCACAGAAUGAAAAACCUCAUCGAUGUUGCAUAGUUG
Target: Human Osteopontin
Target chemistry: Protein
Affinity: 18 nM 
Reference: Z Mi et al. RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells. Molecular Therapy 17(2009): 153-161Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Platelet-Derived Growth Factor (PDGF) B-chain (36t) (ID# 7738)
Aptamer chemistry: DNA
Aptamer sequence: CACAGGCTACGGCACGTAGAGCATCACCATGATCCTGTGT
Target: Platelet-Derived Growth Factor -BB (PDGF-BB)
Target chemistry: Protein
Affinity: 0.093 nM 
Reference: Green, L., et al. "Inhibitory DNA Ligands to Platelet-Derived Growth Factor B-Chain." Journal of Biochemistry, 35(1996): 14413-14424.  Stejskalov?­, Anna & Oliva, Nuria & J England, Frances & Almquist, Benjamin. (2019). Biologically Inspired, Cell-Selective Release of Aptamer-Trapped Growth Factors by Traction Forces. Advanced Materials. 1806380. 10.1002/adma.201806380.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Antigen binding fragment of antivesicular stomatitis virus polyclonal antibodies (C5S) (ID# 7755)
Aptamer chemistry: DNA
Aptamer sequence: TGTGCCAAAGAGAGTGGTGGGGGGGTGGGCGGAACTCGCG
Target: Antigen binding fragment (Fab) of antivesicular stomatitis virus (VSV) rabbit polyclonal antibodies
Target chemistry: Protein
Affinity: Not Mentioned in Database
Reference: D Maharemagic et al. Anti-Fab aptamers for shielding virus from neutralizing antibodies. JACS 134(2012): 17168-17177.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Tumor Endothelial Cells (AraHH001) (ID# 7856)
Aptamer chemistry: DNA
Aptamer sequence: ACGTACCGACTTCGTATGCCAACAGCCCTTTATCCACCTC
Target: Mouse and Human Tumour Endothelial Cells (mTECs and hTECs)
Target chemistry: Cells
Affinity: 43.8 nM 
Reference: Ara N, Hyodo M, Ohga N, Hida, N, Harishima H. (2012) Development of a novel DNA aptamer ligand targeting to primary cultured tumor endothelial cells by a cell-based SELEX method. PLOS one 7: e50174.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Swine Influenza A Virus – H3N2 (HA68) (ID# 7858)
Aptamer chemistry: DNA
Aptamer sequence: ACTCCGTCATCTTTAGTGGCCCCAATGTCGTTATCACCGA
Target: Recombinant H3 cluster IV
Target chemistry: Protein
Affinity: 7.1 nM 
Reference: Wongphatcharachai, Manoosak, et al. "Neutralizing DNA Aptamers against Swine Influenza H3N2 Viruses." Journal of Clinical Microbiology 2013, 51(1):46.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Celiac disease Aptamer (Gli4) (ID# 7895)
Aptamer chemistry: DNA
Aptamer sequence: CCAGTCTCCCGTTTACCGCGCCTACACATGTCTGAATGCC
Target: 33-mer (immunodominant peptide from alpha2-gliadin)
Target chemistry: Peptide
Affinity: 61 nM 
Reference: Gonzalez, S, et. al. "Aptamer Binding to Celiac Disease-Triggering Hydrophobic Proteins A Sensitive Gluten Detection Approach." 2014. Analytical Chemistry 86: 2733-39.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: S132B-C22 (ID# 7920)
Aptamer chemistry: RNA
Aptamer sequence: GACAGCGUGCCUAGAAGUCCAAGCUUAAAUAACCACGCUCGACAAGC
Target: Botulinum Neuroxin Type A (BoNT/A)
Target chemistry: Protein
Affinity: 0.8 nM 
Reference: Tzuu-Wang Chang, Michael Blank, Pavithra Janardhanan, Bal Ram Singh, Charlene Mello,  Michael Blind, Shuowei Cai, "In vitro selection of RNA aptamers that inhibit the activity of type  A botulinum neurotoxin" Biochemical and Biophysical Research Communications 396 (2010) 854ƒ??860.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Myo40-7-27 (ID# 7954)
Aptamer chemistry: DNA
Aptamer sequence: CCCTCCTTTCCTTCGACGTAGATCTGCTGCGTTGTTCCGA
Target: Myoglobin
Target chemistry: Protein
Affinity: 4.93 nM 
Reference: Wang, Q., et al. ƒ??Sensitive point-of-care monitoring of cardiac biomarker myoglobin using aptamer and ubiquitous person glucose meter.ƒ? Biosensors and Bioelecgtronics, 64 (2015): 161-164.   Wang, Q., et al. ƒ??Screening of DNA Aptamers against Myoglobin Using a Positive and Negative Selection Units Integrated Microfluid Chip and its Biosensing Application.ƒ? Analytical Chemistry, 86 (2014): 6572-6579.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: C5s Anti-Antibody (ID# 7959)
Aptamer chemistry: DNA
Aptamer sequence: ACTAGGACGCTTGGGAGGGGGGGTGGGGTGTCCGGTCGCG
Target: Anti-Vesicular Stomatitis Antibody
Target chemistry: Antibody
Affinity: n/a nM 
Reference: Muharemagic D, Zamay A, Ghobadloo SM, Evgin L, Savitskaya A, et al. (2014) Aptamer-Facilitated Protection of Oncolytic Virus from Neutralizing Antibodies. Molecular Therapy--Nucleic Acids 3, e167. doi: 10.1038/mtna.2014.19Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: CCFM641-5 (ID# 7983)
Aptamer chemistry: DNA
Aptamer sequence: TGCGTGAGCGGTAGGCCCCTACGACCCACTGTGGTTGGGC
Target: Unknown Membrane Protien
Target chemistry: Protein
Affinity: 10.69 +/- 0.89 nM 
Reference: Hu, Lujun, et al. "Selection, Characterization and Interaction Studies of a DNA Aptamer for the Detection of Bifidobacterium bifidum" International Journal of Molecular Sciences 10.3390(2017): 833.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: NS13 (ID# 8074)
Aptamer chemistry: DNA
Aptamer sequence: ACTTGCTCTGATGCGACAACCTTTTGCCCAGATAGTAAGT
Target: N‑Cadherin Protein
Target chemistry: Protein
Affinity: 93 nM 
Reference: Yang, L., Gao, T., Li, W., Luo, Y., Ullah, S., Fang, X., … Pei, R. (2020). Ni-Nitrilotriacetic Acid Affinity SELEX Method for Selection of DNA Aptamers Specific to the N-Cadherin Protein. ACS Combinatorial Science. doi:10.1021/acscombsci.0c00165Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: C7 (ID# 8076)
Aptamer chemistry: DNA
Aptamer sequence: GGCCATTGTGGACTTCTTTGGGTAATTCAGGGGCTCGATT
Target: Rituximab
Target chemistry: Protein
Affinity: 8.8 nM 
Reference: Kohlberger M, Wildner S, Regl C, Huber CG, Gadermaier G. Rituximab-specific DNA aptamers are able to selectively recognize heat-treated antibodies. PLoS One. 2020 Nov 5;15(11):e0241560. doi: 10.1371/journal.pone.0241560. PMID: 33151990; PMCID: PMC7644011.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: C10 (ID# 8077)
Aptamer chemistry: DNA
Aptamer sequence: ACTTCGGCTAGTTAGGGGGTAGTTTAGATCGTCTCTACAT
Target: Rituximab
Target chemistry: Protein
Affinity: 17.6 nM 
Reference: Kohlberger M, Wildner S, Regl C, Huber CG, Gadermaier G. Rituximab-specific DNA aptamers are able to selectively recognize heat-treated antibodies. PLoS One. 2020 Nov 5;15(11):e0241560. doi: 10.1371/journal.pone.0241560. PMID: 33151990; PMCID: PMC7644011.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.