rpgv/AptaCom huggingface dataset:
Aptamer: OX40 (Aptamer 9.8) (ID# 7726)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGGAGGACGAUGCGGCAGUCUGCAUCGUAGGAAUCGCCACCGUAUACUUUCCCACCAGACGACUCGCUGAGGAUCCGAGA
Target: Murine OX40 (a tumor necrosis factor (TNF) receptor on the surface of T Cells)
Target chemistry: Protein
Affinity: 8 nM 
Reference: C M Dollins et al. Assembling OX40 aptamers on a molecular scaffold to create a receptor-activating aptamer. Chem Biol. 15(2008):675-682.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Anti-NF-kB p65 (R2) (ID# 7753)
Aptamer chemistry: RNA
Aptamer sequence: GAAGCUUUCACACAACAAGGCCCGGGACUGUAUUAGGGAAAUUAGAGUACAGACAGUCGCCGUGGGUCGAAUUCCGCUCA
Target: NF-kB p65
Target chemistry: Protein
Affinity: 25 nM 
Reference: Wurster, S. E, and Maher, L. J. "Selection and characterization of anti-NF-kB p65 aptamers." RNA, 14(2008): 1037-1047.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: ATP-inhibited molecular switch (ID# 7764)
Aptamer chemistry: RNA
Aptamer sequence: GGGCGACCCUGAUGAGAUGGGGAAGAAACUGUGGCACUUCGGUGCCAGCCUCUCGAAACGGUGAAAGCCGUAGGUUGCCC
Target: ATP
Target chemistry: Small Organic
Affinity: na nM 
Reference: Garrett A. Soukup and Ronald R. Breaker. "Engineering precision RNA molecular switches" Proc. Natl. Acad. Sci.  96(1999):3584-3589.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Neuropeptide Y (Clone 4.31) (ID# 7805)
Aptamer chemistry: DNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGCAAACCACAGCCTGAGTGGTTAGCGTATGTCATTTACGGACCTATGCGTGCTACCGTGAA
Target: Neuropeptide Y (NPY)
Target chemistry: Peptide
Affinity: 300 nM 
Reference: S.D. Mendonsa and M.T. Bowser. In vitro selection of aptamers with affinity for neuropeptide Y using capillary electrophoresis. J. Am. Chem. Soc. 127(2005): 9382-9383.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Lysozyme (Clone 1) (ID# 7823)
Aptamer chemistry: DNA
Aptamer sequence: GGGAATGGATCCACATCTACGAATTCATCAGGGCTAAAGAGTGCAGAGTTACTTAGTTCACTGCAGACTTGACGAAGCTT
Target: Hen egg white lysozyme
Target chemistry: Protein
Affinity: 29-31 nM 
Reference: Cox JC and Ellington AD. (2001) Automated selection of anti-protein aptamers. Bioorg. Med. Chem. 9: 2525 - 2531.    Kirby R, et al. (2004) Aptamer-based sensor arrays for the detection and quantitation of proteins. Anal. Chem. 76: 4066 - 4075.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Kanamycin A (sla 110) (ID# 7831)
Aptamer chemistry: RNA
Aptamer sequence: GGGAAUGGAUCCACAUCUACGAAUUCGAAUUGCCGUAAUUUCCCGUGGAGCGAUGCUUCACUGCAGACUUGACGAAGCUU
Target: Kanamycin A
Target chemistry: Protein
Affinity: <300 nM 
Reference: Lato et al. "In vitro selection of RNA lectins: using combinatorial chemistry to interpret ribozyme evolution." Chemistry & Biology, 2(1995): 291-303.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Lysergamine (M3.2) (ID# 7835)
Aptamer chemistry: DNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGGCGTCAGCCCCGATCGCCATCCAGGGACTCCCCCCTACTGCCTATGCGTGCTACCGTGAA
Target: Lysergamine, metergoline, and other small ergot alkaloids
Target chemistry: Protein
Affinity: 44 nM 
Reference: ER Martin et al. (2012) Aptamer-based molecular recognition of lysergamine, metergoline and small ergot alkaloids. Int. J. Mol. Sci. 13: 17138-17159.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Bacillus anthracis spores (Ba) (ID# 7850)
Aptamer chemistry: DNA
Aptamer sequence: ACCCCTGCATCCTTTGCTGGAGAGGAATGTATAAGGATGTTCCGGGCGTGTGGGTAAGTCAGTCTAGAGGGCCCCAGAAT
Target: Bacillus anthracis spores
Target chemistry: Other
Affinity: 1.5x10^12 CFU/mL 
Reference: Fan, M. et al. "Aptamer selection express: A novel method for rapid single-step selection and sensing of aptamers." Journal of Biomolecular Technologies, 19 (2008): 311-321.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: 14-16 (ID# 7865)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGGAGGACGAUGCGGCAGUGCCCAACCGGAACAACAACCACCGGCGGCUCCUGCUCAGACGACUCGCUGAGGAUCCGAGA
Target: Mouse P68 RNA Helicase (Ddx5)
Target chemistry: Protein
Affinity: 30.8 nM 
Reference: Mi et al. ƒ??In vivo selection of tumor-targeting RNA motifsƒ?. Nature Chemical Biology 1(2010): 22-24. DOI: 10.1038/NCHEMBIO.277Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Aptamer ID 1 (ID# 7896)
Aptamer chemistry: DNA
Aptamer sequence: TCCCACGCATTCTCCACATCATAAGCTGAGCATCTTAGATCCCCGTCAAGGGCAGCGTAACCTTTCTGTCCTTCCGTCAC
Target: PDGF-BB
Target chemistry: Protein
Affinity: 2.7 nM 
Reference: Cho et al. "Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing." PNAS 2010, 1-6/Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Aptamer ID 2 (ID# 7897)
Aptamer chemistry: DNA
Aptamer sequence: TCCCACGCATTCTCCACATCGATACTGAGCATCGTACATGATCCCGCAACGGGCAGTATTCCTTTCTGTCCTTCCGTCAC
Target: PDGF-BB
Target chemistry: Protein
Affinity: 2.5 nM 
Reference: Cho et al. "Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing." PNAS 2010, 1-6.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Aptamer ID 3 (ID# 7898)
Aptamer chemistry: DNA
Aptamer sequence: TCCCACGCATTCTCCACATCAGTTGAATGGTGTGGTCACTTCCAGTCCCGCAGGGCACACCCTTTCTGTCCTTCCGTCAC
Target: PDGF-BB
Target chemistry: Protein
Affinity: 2.6 nM 
Reference: Cho et al. "Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing." PNAS 2010, 1-6.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Mycoplasma bovis detection aptamer (WKB-14) (ID# 7899)
Aptamer chemistry: DNA
Aptamer sequence: GCTGCAATACTCATGGACAGGTTGCGAAAGACAACGAATGCTTTGCCTGCCATAATTTGCGTCTGGAGTACGACCCTGAA
Target: P48 of M. Bovis
Target chemistry: Protein
Affinity: 15.61 nM 
Reference: Fu, P., et. al. Enzyme linked aptamer assay: based on a competition format for sensitive detection of antibodies to Mycoplasma bovis in serum.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: A1 (ID# 7912)
Aptamer chemistry: DNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGAGGCGATTACGCTTCTTGTACTTCAATAACGACTCAACTCCCTATGCGTGCTACCGTGAA
Target: Staphylococcus aureus enterotoxin A (SEA)
Target chemistry: Protein
Affinity: 92.17 nM 
Reference: Huang, Y. et al. "Selection, identification and application of a DNA aptamer against Staphylococcus aureus enterotoxin A." Anal. Methods, 2014, 6, 690-697.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: A15 (ID# 7913)
Aptamer chemistry: DNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGTACTTATGCATTTCCTCCCACGATCTTATTTGAGAGTGACCCTATGCGTGCTACCGTGAA
Target: Staphylococcus aureus enterotoxin A (SEA)
Target chemistry: Protein
Affinity: 48.57 nM 
Reference: Huang, Y. et al. "Selection, identification and application of a DNA aptamer against Staphylococcus aureus enterotoxin A." Anal. Methods, 2014, 6, 690-697.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: A23.2 (ID# 7914)
Aptamer chemistry: DNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGATGATCGTAGTCATTTAAAATTTGAATACTATCAAAGTTACCTATGCGTGCTACCGTGAA
Target: Staphylococcus aureus enterotoxin A (SEA)
Target chemistry: Protein
Affinity: 235 nM 
Reference: Huang, Y. et al. "Selection, identification and application of a DNA aptamer against Staphylococcus aureus enterotoxin A." Anal. Methods, 2014, 6, 690-697.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Peanuts (Ara h 1) Aptamer (ID# 8003)
Aptamer chemistry: DNA
Aptamer sequence: TCGCACATTCCGCTTCTACCGGGGGGGTCGAGCTGAGTGGATGCGAATCTGTGGGTGGGCTTCGCACACACGGACTTACG
Target: Ara h 1
Target chemistry: Protein
Affinity: 419 nM 
Reference: Tran, D. T., Knez, K., Janssen, K. P., Pollet, J., Spasic, D., & Lammertyn, J. (2013). Selection of aptamers against Ara h 1 protein for FO-SPR biosensing of peanut allergens in food matrices. Biosensors and Bioelectronics, 43, 245–251. doi:10.1016/j.bios.2012.12.022Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: DE3A (ID# 8020)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGGAGGACGAUGCGGCCGAUUAGAACUGGGCUGAGGCGUUCUGCAUUUCGGUGAUCAGACGACUCGCUGAGGAUCCGAGA
Target: Sickle Hemoglobin
Target chemistry: Protein
Affinity: 1.68 µM 
Reference: Purvis, S. H., Keefer, J. R., Fortenberry, Y. M., Barron-Casella, E. A., & Casella, J. F. (2017). Identification of Aptamers That Bind to Sickle Hemoglobin and Inhibit Its Polymerization. Nucleic Acid Therapeutics, 27(6), 354–364. doi:10.1089/nat.2016.0646Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: IFNα-3 (ID# 8063)
Aptamer chemistry: DNA
Aptamer sequence: GTCTTGACTAGTTACGCCCACAAGAACCTGCTTGCCATGGTGACGCCGATCATGCTTTTTGGTCATTCAGTTGGCGCCTC
Target: Cytokine interferon alpha (IFN-α)
Target chemistry: Protein
Affinity: 3.96 ± 0.36 nM 
Reference: Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: SMZ1 (ID# 8090)
Aptamer chemistry: DNA
Aptamer sequence: GACAGGCAGGACACCGTAACGTTAGACGCTGGACCGCGTGTGATCGGGTCAGCTGCAATTCTGCTACCTCCCTCCTCTTC
Target: Sulfamethazine (SMZ)
Target chemistry: Small Organic
Affinity: 167.8 nM 
Reference: Kou, Q., Wu, P., Sun, Q., Li, C., Zhang, L., Shi, H., … Le, T. (2020). Selection and truncation of aptamers for ultrasensitive detection of sulfamethazine using a fluorescent biosensor based on graphene oxide. Analytical and Bioanalytical Chemistry. doi:10.1007/s00216-020-03044-2 Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: A5 (ID# 8091)
Aptamer chemistry: DNA
Aptamer sequence: TCGCACATTCCGCTTCTACCCATGGCTAGGTGTTTATTAATCCTGTAGGATTTGCGGAATCGTAAGTCCGTGTGTGCGAA
Target: GLUT1 Glucose transporter
Target chemistry: Small Organic
Affinity: 160 ± 49 nM nM 
Reference: Rosch, J.C., Neal, E.H., Balikov, D.A. et al. CRISPR-Mediated Isogenic Cell-SELEX Approach for Generating Highly Specific Aptamers Against Native Membrane Proteins. Cel. Mol. Bioeng. 13, 559–574 (2020). https://doi.org/10.1007/s12195-020-00651-yMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: M02 (ID# 8126)
Aptamer chemistry: DNA
Aptamer sequence: CTTCTGCCCGCCTCCTTCCCGGTCGAGACCCGGGTTTACTTCCTCGGTAGTGTTCGAGGGAGACGAGATAGGCGGACACT
Target: Myoglobin (Mb)
Target chemistry: Protein
Affinity: 46.3 nM 
Reference: Ma, Y.; Li, W.; Xing, R.; Li, P.; Liu, Z. Epitope-Imprinted Magnetic Nanoparticles as a General Platform for Efficient In Vitro Evolution of Protein-Binding Aptamers. ACS Sens. 2020 Jul 7; 5(8): 2537-2544. DOI: 10.1012/acssensors.0c00846Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: M03 (ID# 8127)
Aptamer chemistry: DNA
Aptamer sequence: CTTCTGCCCGCCTCCTTCCCGGGTTACAGGATCGTAAATCTTATTCGTTGCTCGATCGGGAGACGAGATAGGCGGACACT
Target: Myoglobin (Mb)
Target chemistry: Protein
Affinity: 46.3 nM 
Reference: Ma, Y.; Li, W.; Xing, R.; Li, P.; Liu, Z. Epitope-Imprinted Magnetic Nanoparticles as a General Platform for Efficient In Vitro Evolution of Protein-Binding Aptamers. ACS Sens. 2020 Jul 7; 5(8): 2537-2544. DOI: 10.1012/acssensors.0c00846Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: B01 (ID# 8128)
Aptamer chemistry: DNA
Aptamer sequence: CTTCTGCCCGCCTCCTTCCTCGTGACGCCGTGCAGTTACCGATACGAGCCTCGTTTTGGGAGACGAGATAGGCGGACACT
Target: β2-Microglobulin (B2M)
Target chemistry: Protein
Affinity: 52.9 nM 
Reference: Ma, Y.; Li, W.; Xing, R.; Li, P.; Liu, Z. Epitope-Imprinted Magnetic Nanoparticles as a General Platform for Efficient In Vitro Evolution of Protein-Binding Aptamers. ACS Sens. 2020 Jul 7; 5(8): 2537-2544. DOI: 10.1012/acssensors.0c00846Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: B03 (ID# 8129)
Aptamer chemistry: DNA
Aptamer sequence: CTTCTGCCCGCCTCCTTCCTATTTATTGAATGCTGTAATTTCGCCACGCGAAAGTAGGGGAGACGAGATAGGCGGACACT
Target: β2-Microglobulin (B2M)
Target chemistry: Protein
Affinity: 36.7 nM 
Reference: Ma, Y.; Li, W.; Xing, R.; Li, P.; Liu, Z. Epitope-Imprinted Magnetic Nanoparticles as a General Platform for Efficient In Vitro Evolution of Protein-Binding Aptamers. ACS Sens. 2020 Jul 7; 5(8): 2537-2544. DOI: 10.1012/acssensors.0c00846Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Apt_NDV01 (ID# 8133)
Aptamer chemistry: DNA
Aptamer sequence: AGTGCAAGCAGTATTCGGTCGGGTCTTGCAGGTCCCGTAGGAGGGGCCATTGGAGTGGGGTAAAGCTGATGCGTGATGCC
Target: Newcastle disease virus (NDV) (avian disease)
Target chemistry: Other
Affinity: 31 nM 
Reference: Marnissi, B.; Kamali-Moghaddam, M.; Ghram, A.; Hmila, I. Generation of ssDNA aptamers as diagnostic tool for Newcastle avian virus. PLoS One. 2020 Aug 13; 15(8): e0237253. DOI: 10.1371/journal.pone.0237253.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Apt_NDV03 (ID# 8134)
Aptamer chemistry: DNA
Aptamer sequence: AGTGCAAGCAGTATTCGGTCCGATGGAGGACCTCCGGTTTACCGTGTCGTTTTACTCTTGTAAAGCTGATGCGTGATGCC
Target: Newcastle disease virus (NDV) (avian disease)
Target chemistry: Other
Affinity: 78.1 nM 
Reference: Reference: Marnissi, B.; Kamali-Moghaddam, M.; Ghram, A.; Hmila, I. Generation of ssDNA aptamers as diagnostic tool for Newcastle avian virus. PLoS One. 2020 Aug 13; 15(8): e0237253. DOI: 10.1371/journal.pone.0237253.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: h-Ras-1 (ID# 8145)
Aptamer chemistry: RNA
Aptamer sequence: CTTCTGCCCGCCTCCTTCCTATTAGGGTGCTTCGCGAAGTTCATTTTACATCCCCATAGGAGACGAGATAGGCGGACACT
Target: h-Ras (Human Ras protein)
Target chemistry: Protein
Affinity: 200 nM 
Reference: Berezovski, M. Musheev, M. Drabovich, A. and Krylov, S. (2006) Non-SELEX Selection of Aptamers. Department of Chemistry, York University. https://doi.org/10.1021/ja056943jMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Sp1 (ID# 8152)
Aptamer chemistry: DNA
Aptamer sequence: TGAGCCCAAGCCCTGGTATGTTCTTCCCTTTTATTAGTCCTGTATTCCTCTACTGTTGCCGGCAGGTCTACTTTGGGATC
Target: Shigella sonnei
Target chemistry: Other
Affinity: 5.98 nM 
Reference: Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Sp20 (ID# 8153)
Aptamer chemistry: DNA
Aptamer sequence: TGAGCCCAAGCCCTGGTATGTCGTCGATTATTGTTTCAGTTCAGTTCCCCCGCGTTCCGAGATCCCAAAGTAGACCTGCC
Target: Shigella sonnei
Target chemistry: Other
Affinity: 14.32 nM 
Reference: Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: h-Ras (ID# 8184)
Aptamer chemistry: DNA
Aptamer sequence: CTTCTGCCCGCCTCCTTCCTATTAGGGTGCTTCGCGAAGTTCATTTTACATCCCCATAGGAGACGAGATAGGCGGACACT
Target: h-Ras protein
Target chemistry: Protein
Affinity: 200 nM 
Reference: Berezovski, M., Musheev. M., Drabovich, A., and S. N. Krylov. 2006. Non-SELEX Selection of Aptamers. Journal of the American Chemical Society. 128, 1410-1411.  doi: 0.1021/ja056943jMiyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: MBMI-01c (ID# 8222)
Aptamer chemistry: DNA
Aptamer sequence: ATTGGCACTCCACGCATAGGTTTGGGGATGGGCAACGGTAAAAAGGGTCAAAAGGCTTTTCCTATGCGTGCTACCGTGAA
Target: α-conotoxin MI (CTX-MI)
Target chemistry: Peptide
Affinity: 0.524 nM 
Reference: Guo, H.; Deng, B.; Zhao, L.; Gao, Y.; Zhang, X.; Yang, C.; Zou, B.; Chen, H.; Sun, M.; Wang, L.; et al.Programmed Aptamer Screening, Characterization, and Rapid Detection for α-Conotoxin MI. Toxins 2022, 14, 706. https://doi.org/10.3390/toxins14100706Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: HSM01 (ID# 8235)
Aptamer chemistry: DNA
Aptamer sequence: ACCGACCGTGCTGGACTCACCGGACAAAACTTCAGTTTTTATTTCCAGATCCTGGGCATTGCGCCAGGCTCGCTCATAGT
Target: Human Skeletal Muscle Cells
Target chemistry: Cells
Affinity: 109.5 nM 
Reference: Shuming Sun, Han Liu, Yan Hu, Yanpeng Wang, Mingri Zhao, Yijun Yuan, Yafei Han, Yingying Jing, Jin Cui, Xiaoxiang Ren, Xiao Chen, Jiacan Su, Selection and identification of a novel ssDNA aptamer targeting human skeletal muscle, Bioactive Materials, Volume 20, 2023, Pages 166-178, ISSN 2452-199X, https://doi.org/10.1016/j.bioactmat.2022.05.016. (https://www.sciencedirect.com/science/article/pii/S2452199X22002377)Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Fibroblast Activation Protein (FAP) (ID# 8243)
Aptamer chemistry: DNA
Aptamer sequence: AGCAGCACAGAGGTCAGATGCCGCAGGCAGCTGCCATTAGTCTCTATCCGTGACGGTATGCCTATGCGTGCTACCGTGAA
Target: Fibroblast Activation Protein (FAP)
Target chemistry: Protein
Affinity: 0.5 nM 
Reference: Zhang X, Yang G, Zhao Y, Dai X, Liu W, Qu F, Huang Y. Selection and Identification of an ssDNA Aptamer for Fibroblast Activation Protein. Molecules. 2023; 28(4):1682. https://doi.org/10.3390/molecules28041682Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Histone H3R8Me2sym (Clone 1) (ID# 7615)
Aptamer chemistry: RNA
Aptamer sequence: GGGACGCGUGGUACCGAUGGGUCAGCAUGUAGCCAGGCAGGGCCGUGUGAGCUUGUGCUGAUGUGAGCUUCCGCGGGGAUC
Target: Histone H3R8Me2sym
Target chemistry: Peptide
Affinity: 12 nM 
Reference: Hyun et al. "An RNA Aptamer That Selectively Recognizes Symmetric Dimethylation of Arginine 8 in the Histone H3 N-Terminal Peptide." Nucleic Acid Therapeutics, 21 (2011): 157-163.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Integrin αV subunit (aV-1) (ID# 7704)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGGAGGACGAUGCGGCACACAUUCCCGUCCUCGAUACGUCUAGGCUUAGUGCCACUUGCUUAAUCCAGACGACUCGCCCGA
Target: Integrin aV subunit
Target chemistry: Protein
Affinity: 2.7 nM 
Reference: Gong, Q. et al,(2012). Selection strategy to generate aptamer pairs that bind to distinct sites on protein targets. Analytical Chemistry, 2012(84), 5365-5371.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Integrin ??3 subunit (??3-1) (ID# 7705)
Aptamer chemistry: 2'-F-RNA
Aptamer sequence: GGGAGGACGAUGCGGCCCAGAUUACUGUGGAGUGGUUGUCUGCGAAUCCUUCGUCCACCCAAUAGCAGACGACUCGCCCGA
Target: Integrin ??3 subunit
Target chemistry: Protein
Affinity: 6.5 nM 
Reference: Gong, Q. et al,(2012). Selection strategy to generate aptamer pairs that bind to distinct sites on protein targets. Analytical Chemistry, 2012(84), 5365-5371.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: ATP-induced molecular switch (ID# 7758)
Aptamer chemistry: RNA
Aptamer sequence: GGGCGACCCUGAUGAGCCUUGGGAAGAAACUGUGGCACUUCGGUGCCAGCACGUCGAAACGGUGAAAGCCGUAGGUUGCCC
Target: ATP
Target chemistry: Small Organic
Affinity: NA nM 
Reference: Garrett A. Soukup and Ronald R. Breaker. "Engineering precision RNA molecular switches" Proc. Natl. Acad. Sci.  96(1999):3584-3589.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: ??-Catenin (ID# 7833)
Aptamer chemistry: RNA
Aptamer sequence: GGACGCGUGGUACCAGGCCGAUCUAUGGACGCUAUAGGCACACCGGAUACUUUAACGAUUGGCUAAGCUUCCGCGGGGAUC
Target: Arm 1-12 of B-catenin
Target chemistry: Protein
Affinity: 5 nM 
Reference: Lee HK, Choi YS, Park YA, et al. (2006) Modulation of oncogenic transcription and alternative splicing by beta-catenin and an RNA aptamer in colon cancer cells.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Leptin (Lep3) (ID# 7864)
Aptamer chemistry: DNA
Aptamer sequence: CTTCTGCCCGCCTCCTTCCGTTAATGGGGGATCTCGCGGCCGTTCTTGTTGCTTATACAGGAGACGAGATAGGCGGACACT
Target: Leptin
Target chemistry: Protein
Affinity: 0.32 µM 
Reference: Ashley J and Li S FY. (2013) Three-dimensional selection of leptin aptamers using capillary electrophoresis and implications for clone validation. Anal Biochem. 434: 146-152.Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Human Norovirus SMV-19 (ID# 7931)
Aptamer chemistry: DNA
Aptamer sequence: AGTATACGTATTACCTGCAGCCACCAGTGTGTTGAGGTTTGAGCACACTGATAGAGTGTCACGATATCTCGGAGATCTTGC
Target: Human Norovirus
Target chemistry: Other
Affinity: 191 nM 
Reference: Escudero-Abarca BI, Suh SH, Moore MD, Dwivedi HP, Jaykus L-A (2014) Selection, Characterization and Application of Nucleic Acid Aptamers for the Capture and Detection of Human Norovirus Strains. PLoS ONE 9(9): e106805. doi:10.1371/journal.pone.0106805Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.
Aptamer: Human Norovirus SMV-21 (ID# 7932)
Aptamer chemistry: DNA
Aptamer sequence: AGTATACGTATTACCTGCAGCCCATGTTTTGTAGGTGTAATAGGTCATGTTAGGGTTTCTGCGATATCTCGGAGATCTTGC
Target: Human Norovirus
Target chemistry: Other
Affinity: 101 nM 
Reference: Escudero-Abarca BI, Suh SH, Moore MD, Dwivedi HP, Jaykus L-A (2014) Selection, Characterization and Application of Nucleic Acid Aptamers for the Capture and Detection of Human Norovirus Strains. PLoS ONE 9(9): e106805. doi:10.1371/journal.pone.0106805Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.