rpgv/AptaCom huggingface dataset:
Aptamer: N13
Aptamer sequence: CACCTAATACGACTCACTATAGCGGATCCGAAGGGGGCGCGAGGTGTAAGGGTGTGGGGTGGTGGGTGGGCCTGGCTCGAACAAGCTTGC
Target: Human Fatty acid binding protein 3 (hFABP3)
Target chemistry: Protein
Affinity: 0.0743 (+/-) 0.0142?M, 
Reference: Kakoti A, Goswami P. Biochimica et Biophysica Acta Multifaceted analyses of the interactions between human heart type fatty acid binding protein and its speci fi c aptamers. BBA - Gen Subj. 2017;1861(1):3289-99.
Aptamer: P45
Aptamer sequence: CACCTAATACGACTCACTATAGCGGATCCGACAGTCCTCTCACCATTCTTCTACATGTAATCTTCCGCGTCCTGGCTCGAACAAGCTTGC
Target: Plasmodium falciparum Lactate dehydrogenase (PfLDH)
Target chemistry: Protein
Affinity: 0.89 (+/-) 0.14, 
Reference: Priyamvada Jain, Babina Chakma, Sanjukta Patra, Pranab Goswami, Hairpin stabilized fluorescent silver nanoclusters for quantitative detection of NAD+ and monitoring NAD+/NADH based enzymatic reactions. Analytica Chimica Acta, 956, 2017, 48-56
Aptamer: P9
Aptamer sequence: CACCTAATACGACTCACTATAGCGGATCCGATTACCCACCCGACTCCCCTAGCATTCTCCATCCAACCGGCCTGGCTCGAACAAGCTTGC
Target: Plasmodium falciparum Lactate dehydrogenase (PfLDH)
Target chemistry: Protein
Affinity: 0.73 (+/-) 0.05, 
Reference: Priyamvada Jain, Babina Chakma, Sanjukta Patra, Pranab Goswami, Hairpin stabilized fluorescent silver nanoclusters for quantitative detection of NAD+ and monitoring NAD+/NADH based enzymatic reactions. Analytica Chimica Acta, 956, 2017, 48-56
Aptamer: P38
Aptamer sequence: CACCTAATACGACTCACTATAGCGGATCCGACAATAATACACTTTGCTCCCCTGTGGCTTTTCGCACTCGCCTGGCTCGAACAAGCTTGC
Target: Plasmodium falciparum Lactate dehydrogenase (PfLDH)
Target chemistry: Protein
Affinity: 0.35 (+/-) 0.02, 
Reference: Priyamvada Jain, Babina Chakma, Sanjukta Patra, Pranab Goswami, Hairpin stabilized fluorescent silver nanoclusters for quantitative detection of NAD+ and monitoring NAD+/NADH based enzymatic reactions. Analytica Chimica Acta, 956, 2017, 48-56
Aptamer: B3
Aptamer sequence: CACCTAATACGACTCACTATAGCGGATCCGAATCAGCAGAAACAAGAATCGACTGTCTTCTCGATAGGGGGCTGGCTCGAACAAGCTTGC
Target: histidine rich protein II (HRP II)
Target chemistry: Protein
Affinity: 8.34 kcal.mole-1, 
Reference: Chakma B, Jain P, Singh NK, Goswami P. Development of Electrochemical Impedance Spectroscopy Based Malaria Aptasensor Using HRP-II as Target Biomarker. Electroanalysis. 2018;30(8):1839-46.
Aptamer: B4
Aptamer sequence: CACCTAATACGACTCACTATAGCGGATCCGAACGGCAATTAGCCCCCTTTCCTCCTGGCCTCGGTCGGCGGCTGGCTCGAACAAGCTTGC
Target: histidine rich protein II (HRP II)
Target chemistry: Protein
Affinity: 20.40 kcal.mole-1, 
Reference: Chakma B, Jain P, Singh NK, Goswami P. Development of Electrochemical Impedance Spectroscopy Based Malaria Aptasensor Using HRP-II as Target Biomarker. Electroanalysis. 2018;30(8):1839-46.
Aptamer: NG51
Aptamer sequence: TCACCTCATACGACTCACTATAGCGGACCCCACTCACTGCTCGGACTCTCCCCCTCCCCGCCTGGCTCGAACAAGCTTGC
Target: Plasmodium falciparum glutamate dehydrogenase (PfGDH)
Target chemistry: Protein
Affinity: 1.1 (+/-) 0.20 micro Molar, 
Reference: Singh NK, Chakma B, Jain P, Goswami P. Protein-Induced Fluorescence Enhancement Based Detection of Plasmodium falciparum Glutamate Dehydrogenase Using Carbon Dot Coupled Specific Aptamer. ACS Comb Sci. 2018;20(6):3507.
Aptamer: NG3
Aptamer sequence: TCACCTCATACGACTCACTATAGCGGATCCGAGCCGGGGTGTTCTGTTGGCGGGGGCGGTGGGCGGGCTGGCTCGAACAAGCTTGC
Target: Plasmodium falciparum glutamate dehydrogenase (PfGDH)
Target chemistry: Protein
Affinity: 0.5 (+/-) 0.04 Micro Molar, 
Reference: Singh NK, Chakma B, Jain P, Goswami P. Protein-Induced Fluorescence Enhancement Based Detection of Plasmodium falciparum Glutamate Dehydrogenase Using Carbon Dot Coupled Specific Aptamer. ACS Comb Sci. 2018;20(6):3507.
Aptamer: Nampt binding aptamer (NBA)
Aptamer sequence: ATACCAGCTTATTCAATTGGGCGGTGGGGGGGGTAGTGGGTGTTATGGCGATCGTGGAGATAGTAAGTGCAATCT
Target: Nampt/Nicotinamide phosphoribosyltransferase
Target chemistry: Protein
Affinity: 72.52 nM, 
Reference: Park, J.-W., Tatavarty, R., Kim, D. W., Jung, H.-T., & Gu, M. B. (2012). Immobilization-free screening of aptamers assisted by graphene oxide. Chem. Commun., 48(15), 20712073. doi:10.1039/c2cc16473f SJ Lee et al. Sensitive detection of adipokines for early diagnosis of type 2 diabetes using enzyme-linked antibody-aptamer sandwich (ELAAS) assays. Sensors Actuat. B-Chem.(2012): 243-248
Aptamer: Taq DNA polymerase (TQ21)
Aptamer sequence: TTCTCGGTTGGTCTCTGGCGGAGCGATCATCTCAGAGCATTCTTAGCGTTTTGTTCTTGTGTATGTTCGCTTTTCCC
Target: Taq DNA polymerase
Target chemistry: Protein
Affinity: 36 pM, 
Reference: Sumedha and Dang. "Oligonucleotide inhibitors of Taq DNA polymerase facilitate detection of low copy number targets by PCR." Journal of Molecular Biology, 264 (1996): 268-78.
Aptamer: A23.2
Aptamer sequence: AGCAGCACAGAGGTCAGATGAAGGTCTTACATCAATTTATATATTTTTCCAATATCTGTCCCTATGCGTGCTACCGTGAA
Target: Staphylococcus aureus enterotoxin A (SEA)
Target chemistry: Protein
Affinity: 235.00 nM, 
Reference: Huang, Y. et al. "Selection, identification and application of a DNA aptamer against Staphylococcus aureus enterotoxin A." Anal. Methods, 2014, 6, 690-697.
Aptamer: Vaccinia virusinfected A549 cells
Aptamer sequence: ATCGTCTGCTCCGTCCAATATGATGACACCTGCATAATTTATAGTGAGTCTTGATTCACGCTGCATTTGGTGTGAGGTCGTGC
Target: Vaccinia virus (WR Strain)infected A549 cells
Target chemistry: Cells
Affinity: 2.7 nM, 
Reference: Tang et al. "Generating Aptamers for Recognition of Virus-Infected Cells." Clin. Chem., 55(2009): 813-822.
Aptamer: Aptamer TY04
Aptamer sequence: ATCGTCTGCTCCGTCCAATATATCAAAGGCGAATTTTGTCAAGGTGTTAAACGATAGTCCCTACCTTTGGTGTGAGGTCGTGC
Target: Multiple myeloma cells (MM.1S
Target chemistry: Cells
Affinity: 3.89 µM, 
Reference: Dai, H. et al. "Aptamer TY04 inhibits the growth of multiple myeloma cells via cell cycle arrest." Tumor Biology 2014: 1-8
Aptamer: Lup an 1 allergen, ß-Conglutin
Aptamer sequence: AGCTGACACAGCAGGTTGGTGGGGGTGGCTTCCAGTTGGGTTGACAATACGTAGGGACACGAAGTCCAACCACGAGTCGAGCAATCTCGAAAT
Target: ß-Conglutin
Target chemistry: Protein
Affinity: 360 nM, 
Reference: P Nadal et al. DNA aptamers against the Lup an 1 food allergen. PLoS One 7(2012):e35253
Aptamer: Botulinum neurotoxin type A (BoNT A) Aptamer
Aptamer sequence: GGGAGGAGGAGAGATGTGAACTTGACAGCGUGCCUAGAAGUCCAAGCUUAAAUAACCACGCUCGACAAGCAGAAACTCTACACTGGACTGGCG
Target: BoNT A Light Chain
Target chemistry: Protein
Affinity: 87 nM, 
Reference: Chang, T., Blank, M., Janardhanan, P., Singh, B., Mello, C., Blind, M., Cai, S. "In vitro selection of RNA aptamers that inhibit the activity of type A botulinum neurotoxin." Biochemical and Biophysical Research Communications 396(2010): 854-860.
Aptamer: HGF (H38-15)
Aptamer sequence: AGATGCCTGTCCAGCATCGAGCGCCAGCTTTGCTGATGGGTGGCCACCCTTGCCCTGGGTTTGAATTTCGATCCTATCGGTAGCTAGACTGCTTTGTCCTCG
Target: Human Hepatocyte Growth Factor
Target chemistry: Protein
Affinity: 19 nM, 
Reference: Saito, Takesh et al. "Generation of Inhibitory DNA Aptamers Against Human Hepatocyte Growth Factor." DNA and Cell Biology, 24 (2005): 624-633.
Aptamer: Crude Extracellular Mixture of E. coli - cis
Aptamer sequence: CACGGATCCTGACAAGGATGTGTGCGTTGTCGAGACCTGCGACCGGAACACTACACTGTGTGGGATGGATTTCTTTACAGTTGTGTGCAGCTCCGTCCGACTCTTCCTAGCInternalFluoresceindTAInternalDabcyldTGGTTCGATCAAGA
Target: Crude Extracellular Mixture (CEM) of E. coli
Target chemistry: Protein
Affinity: N/A nM, 
Reference: Ali et al. "Fluorogenic DNAzyme Probes as Bacterial Indicators." Angewandte Chemie International Edition, 50 (2011): 3751-3754.
Aptamer: Clone 2
Aptamer sequence: CGACTGCAGAGCTTGCTACGTTGTAATTCAAAACAAAGGTTTCCTGGACTCCCCGCAGGTCTTGTGAATGGTACCGAGCTCGAATTCCC
Target: Protein E (PE)
Target chemistry: Protein
Affinity: 1.2 nM, 
Reference: Barfod, Anders et al. "In Vitro Selection of RNA Aptamers Directed Against Protein E: A Haemophilus influenzae Adhesin." Mol Biotech, 2014: 1-12
Aptamer: HIV-1 R5 SU Glycoprotein gp120 (B40t77)
Aptamer sequence: GGGAGACAAGACUAGACGCUCAAUGUGGGCCACGCCCGAUUUUACGCUUUUACCCGCACGCGAUUGGUUUGUUUCCC
Target: HIV-1 R5 gp120
Target chemistry: Protein
Affinity: 31 nM, 
Reference: A. K. Dey et. al. Structural characterization of an anti-gp120 RNA aptamer that neutralizes R5 strains of HIV-1. RNA 11:873-884
Aptamer: Integrin ß3 subunit (ß3-1)
Aptamer sequence: GGGAGGACGAUGCGGCCCAGAUUACUGUGGAGUGGUUGUCUGCGAAUCCUUCGUCCACCCAAUAGCAGACGACUCGCCCGA
Target: Integrin ß3 subunit
Target chemistry: Protein
Affinity: 6.5 nM, 
Reference: Gong, Q. et al,(2012). Selection strategy to generate aptamer pairs that bind to distinct sites on protein targets. Analytical Chemistry, 2012(84), 5365-5371.
Aptamer: Human Nonpancreatic Secretory Phospholipase A2 (Aptamer 15)
Aptamer sequence: GGGAAAAGAGACGGCCGGCGCCAUAGCCGAGAUCCGAGGUGUUGCCGAGAA
Target: Human Nonpancreatic Secretory Phospholipase A2 (hnps-PLA2)
Target chemistry: Small Organic
Affinity: 1.7 nM, 
Reference: Bridonneau, P., et al. "High-Affinity Aptamers Selectively Inhibit Human Nonpancreatic Secretory Phospholipase A2 (hnps-PLA2)." Journal of Medicinal Chemistry, 41(1998): 778-786.
Aptamer: Vascular Permeability Factor/Vascular Endothelial Growth Factor (NX-213)
Aptamer sequence: TTTTACCCUGAUGGUAGACGCCGGGGUGTTTT
Target: Vascular Permeability Factor/Vascular Endothelial Growth Factor (VPF/VEGF)
Target chemistry: Protein
Affinity: 140 pM, 
Reference: Green L, Jellinek D, Janjic N, et al. (1995) "Nuclease-resistant nucleic acid ligands to vascular permeability factor/vascular endothelial growth factor." Chem Biol. 2:683-695.
Aptamer: Moloney Murine Leukemia Virus
Aptamer sequence: UUACCACGCGCUCUUAACUGCUAGCGCCAUGGC
Target: Moloney Murine Leukemia Virus
Target chemistry: Protein
Affinity: 6.9 nM, 
Reference: Selection of High-Affinity RNA Ligands to Reverse Transcriptase: Inhibition of cDNA Synthesis and RNase H Activity." Journal of Biochemistry, 33(1994)
Aptamer: Basic Fibroblast Growth Factor
Aptamer sequence: GGUGAAGGCAACGUAUAGGCAAGCACACUUCACC
Target: Basic Fibroblast Growth Factor
Target chemistry: Protein
Affinity: 190 pM, 
Reference: Jellinek, D., et al. "High-affinity RNA ligands to basic fibroblast growth factor inhibit receptor binding." Proceedings of the National Academy of Sciences of the United States of America, 90(1993):
Aptamer: Avian Myeloblastosis Virus (a.1.1)
Aptamer sequence: CGUCCCGUGCGCAAAAGUUCUUAGCGCUAGCAGUCCUAGUUGC
Target: Avian Myeloblastosis Virus (AMV)
Target chemistry: Protein
Affinity: 0.5 nM, 
Reference: Chen and Gold. "Selection of High-Affinity RNA Ligands to Reverse Transcriptase: Inhibition of cDNA Synthesis and RNase H Activity." Journal of Biochemistry, 33(1994)
Aptamer: Dopamine (dopa2/c.4) (ID# 401)
Aptamer sequence: GGGAAUUCCGCGUGUGCGCCGCGGAAGAGGGAAUAUAGAGGCAGCACAUAGUGAGGCCCUCCUCCC
Target: Dopamine
Target chemistry: Small Organic
Affinity: 1.0 pM, 
Reference: (A)Sequence from C Mannironi, et al. "In Vitro Selection of Dopamine RNA Ligands." Biochemistry, 36 (1997): 9726-973. (B) Enzyme-linked assay from H Park and I R Paeng. "Development of direct competitive enzyme-linked aptamer assay for determination of dopamine in serum." Analytica Chimica Acta, 685 (2011): 65-73.
Aptamer: FMN-induced molecular switch (ID# 395)
Aptamer sequence: GGGCGACCCCUGAUGAGCCUUAGGAUAUGCUUCGGCAGAAGGACGUCGAAACGGUGAAAGCCGUAGGUUGCCC
Target: flavin mononucleotide (FMN)
Target chemistry: Small Organic
Affinity: na nM, 
Reference: Garrett A. Soukup and Ronald R. Breaker. "Engineering precision RNA molecular switches" Proc. Natl. Acad. Sci. 96(1999):3584-3589.
Aptamer: Lysozyme (ID# 162)
Aptamer sequence: GGGAAUGGAUCCACAUCUACGAAUUCAUCAGGGCUAAAGAGGCAGAGUUACUUAGUUCACUGCAGACUUGACGAAGCUU
Target: Lysozyme
Target chemistry: Protein
Affinity: 31 nM, 
Reference: Cox and Ellington. "Automated Selection of Anti-Protein Aptamers." Bioorganic & Medicinal Chemsitry, 9 (2001): 2525-2531/
Aptamer: Interleukin 10 (IL-10) (R5A1) (ID# 291)
Aptamer sequence: GGGCUCAUGCACGUUUGCUCCUGUAAUUGGCGUAUGUAACCCAGGCACCAAACACCCCAGGCCGGGCCAUGAUCCACAUA
Target: Interleukin -10 (IL-10)
Target chemistry: Protein
Affinity: 12 nM, 
Reference: Berezhnoy, A, et al. (2012). Isolation and optimization of murine il-10 receptor blocking oligonucleotide aptamers using high- throughput sequencing. The American Society of Gene & Cell Therapy
Aptamer: Interleukin 32 (IL-32) (AC3-3)
Aptamer sequence: GGGUUCACUGCAGACUUGACGAAGCUUCCGGAGAGAAGGGUCAAAGUUGUGCGGGAGUGUGUUGUGGAAUGGAUCCACAUCUACGAAUUC
Target: Interleukin-32
Target chemistry: Protein
Affinity: 78 nM, 
Reference: Kim et al. "Generation of Antagonistic RNA Aptamers Specific to Proinflammatory Cytokine Interleukin-32." Bulletin of the Korean Chemical Society, 31 (2010): 3561-3566.
Aptamer: HER-2 (S6)
Aptamer sequence: GGGAGAUACCAGCUUAUUCAAUUUGGAUGGGGAGAUCCGUUGAGUAAGCGGGCGUGUCUCUCUGCCGCCUUGCUAUGGGGAGAUAGUAAGUGCAAUCU
Target: HER-2
Target chemistry: Cells
Affinity: 94.6 nM, 
Reference: Kang, H. (2009). Isolation of RNA aptamers targeting Her-2-overexpressing breast cancer cells using cell-selex. Bull. Korean Chem. Soc., 30(8), 182-1831.
Aptamer: Amyloid Peptide BetaA4(1 40) (B55)
Aptamer sequence: GGGAAUUCGAGCUCGGUACCUUUACCGUAAGGCCUGUCUUCGUUUGACAGCGGCUUGUUGACCCUCACACUUUGUACCUGCUGCCAACUGCAGGCAUGCAAGCUUGG
Target: Amyloid Peptide BetaA4(1 40)
Target chemistry: Peptide
Affinity: 29 nM, 
Reference: Ylera, Francisco, et al. "Selection of RNA Aptamers to the Alzheimer's Disease Amyloid Peptide." Biochemical and Biophysical Research Communities, 290 (2002): 1583-1588.
Aptamer: Lup an 1 allergen ?-conglutin (SGQ)
Aptamer sequence: GGTGGGGGTGG
Target: ?-conglutin
Target chemistry: Protein
Affinity: 0.58 nM, 
Reference: P Polo. Selection, characterisation and analytical application of DNA aptamer against the anaphylactic toxic allergen, ?-conglutin, Lup an 1. (Doctoral Thesis). Retrieved from Tesis Doctorals en Xarxa
Aptamer: IR-A48
Aptamer sequence: CGCCTGGNGNNAAGACAACCNCNAGGNCAGGCG
Target: Insulin Receptor
Target chemistry: Protein
Affinity: 3.5 nM, 
Reference: Yunn N, Koh A, Han S, Lim JH, Park S, et al. (2015) Agonistic Aptamer to the Insulin Receptor Leads to Biased Signaling and Functional Selectivity Through Allosteric Modulation. Nucleic Acids Research 1. doi:10.1093/narlgkv767
Aptamer: Plasmodium vivax lactate dehydrogenase (pL1)
Aptamer sequence: GTTCGATTGGATTGTGCCGGAAGTGCTGGCTCGAAC
Target: Plasmodium vivax lactate dehydrogenase (PvLDH)
Target chemistry: Protein
Affinity: 16.8 nM, 
Reference: Seonghwan, L. (2012). A highly sensitive aptasensor towards plasmodium lactate dehydrogenase for the diagnosis of malaria. Biosensors and Bioelectronics, 35(2012), 291-296.
Aptamer: Plasmodium falciparum lactate dehydrogenase (pL1)
Aptamer sequence: GTTCGATTGGATTGTGCCGGAAGTGCTGGCTCGAAC
Target: Plasmodium falciparum lactate dehydrogenase (PfLDH)
Target chemistry: Protein
Affinity: 38.7 nM, 
Reference: Seonghwan, L. (2012). A highly sensitive aptasensor towards plasmodium lactate dehydrogenase for the diagnosis of malaria. Biosensors and Bioelectronics, 35(2012), 291-296.
Aptamer: Plasmodium vivax lactate dehydrogenase (pL2)
Aptamer sequence: GAACTCATTGGCTGGAGGCGGCAGTACCGCTTGAGTTC
Target: Plasmodium vivax lactate dehydrogenase (PvLDH)
Target chemistry: Protein
Affinity: 31.7 nM, 
Reference: Seonghwan, L. (2012). A highly sensitive aptasensor towards plasmodium lactate dehydrogenase for the diagnosis of malaria. Biosensors and Bioelectronics, 35(2012), 291-296.
Aptamer: Plasmodium falciparum lactate dehydrogenase (pL2)
Aptamer sequence: GAACTCATTGGCTGGAGGCGGCAGTACCGCTTGAGTTC
Target: Plasmodium falciparum lactate dehydrogenase (PfLDH)
Target chemistry: Protein
Affinity: 49.6 nM, 
Reference: Seonghwan, L. (2012). A highly sensitive aptasensor towards plasmodium lactate dehydrogenase for the diagnosis of malaria. Biosensors and Bioelectronics, 35(2012), 291-296.
Aptamer: HIV-1 Reverse Transcriptase (R1T)
Aptamer sequence: CGCCTGATTAGCGATACTCAGCGTTGGGTGGGTGGGTGGG
Target: HIV-1 RT
Target chemistry: Protein
Affinity: 1.1 nM, 
Reference: (A) D Michalowski et al. Novel bimodular DNA aptamers with guanosine quadruplexes inhibit phylogenetically diverse HIV-1 reverse transcriptases. Nucleic Acid Res. 36(2008): 7124-7135. (B) Y-T Lai and J DeStefano. DNA aptamers to human immunodeficiency virus reverse transcriptase selected by a primer-free SELEX method: characterization and comparison with other aptamers. Nucleic Acid Therapeutics 22(2012): 162-176
Aptamer: HMBA (aptabeacon)
Aptamer sequence: FAMCAGGTTGGTCTGGTTGGGTTGGCTCCTGTGTACGCAACCTG
Target: 6X His-tag
Target chemistry: Protein
Affinity: ~4.2 nM, 
Reference: X Tan et al. Molecular beacon aptamers for direct and universal quantitation of recombinant proteins from cell lysates. Anal. Chem. [published online ahead of print August 23, 2012]. doi: 10.1021/ac301764q
Aptamer: Epithelial Cell Adhesion Molecule (EpCAM) SYL3C
Aptamer sequence: CACTACAGAGGTGTCTGTCCCACGTTGTCATGGGGGGTTGGCCTG
Target: Cancer Cells
Target chemistry: Cells
Affinity: 38 nM, 
Reference: Selection of DNA Aptamers against Epithelial Cell Adhesion Molecule for Cancer Cell Imaging and Circulating Tumor Cell Capture Yanling Song, Zhi Zhu, Yuan An, Weiting Zhang, Huimin Zhang, Dan Liu, Chundong Yu, Wei Duan, and Chaoyong James Yang Analytical Chemistry 2013 85 (8), 4141-4149 DOI: 10.1021/ac400366b
Aptamer: L-Selectin (LD201t1)
Aptamer sequence: TAGCCAAGGTAACCAGTACAAGGTGCTAAAACGTAATGGCTTCGGCTTAC
Target: L-Selectin binding to sialyl Lewis X
Target chemistry: Protein
Affinity: 3 nM, 
Reference: Hicke, Brain, et al. "DNA Aptamers Block L-Selectin Function In Vivo Inhibition of Human Lymphocyte Traf?cking in SCID Mic." Journal of Clinical Investigation, 98 (1996): 2688-2692
Aptamer: Digoxin (Truncated D1)
Aptamer sequence: AGCGAGGGCGGTGTCCAACAGCGGTTTTTTCACGAGGGAGGTTGGCGGTGG
Target: Digoxin
Target chemistry: Protein
Affinity: 0.05 nM, 
Reference: Z Kiani et al. In vitro selection and characterization of deoxyribonucleic acid aptamers for digoxin. Analytica Chimica Acta 748(2012): 67-72.
Aptamer: Isocarbophos (SS4-54)
Aptamer sequence: AAGCTTTTTTGACTGACTGCAGCGATTCTTGATCGCCACGGTCTGGAAAAAGAT
Target: Isocarbophos
Target chemistry: Small Organic
Affinity: 0.9 µM, 
Reference: Wang, L, et al. (2012). Selection of DNA aptamers that bind four organophosphorus pesticides. Biotechnol Lett, 2012(34), 869-874. doi: 10.1007/s10529-012-0850-6
Aptamer: Antibac1
Aptamer sequence: TCGCGGCGAGTCGTCTGGGGACAGGGAGTGCGCTGCTCCCCCCGCATCGTCCTCCC
Target: peptidoglycan
Target chemistry: Other
Affinity: 268.50 nM, 
Reference: A Graziani et al. High efficiency binding aptamers for a wide range of sepsis 1 bacterial agents. JMB Papers in Press. 2017: JMB16-11004.
Aptamer: Fc? receptor III? / CD16? (CLN0020)
Aptamer sequence: GGAGGGAAAAGTTATCAGGCCACTGCGGGGGTCCTATACGTGAGGAAGAAGTGGGCAGGTC
Target: Fc?rIII? / FcgrIIIa / CD16a
Target chemistry: Protein
Affinity: 22 nM, 
Reference: Boltz A, Plater B, Hock B, et al. (2011) Bi-specific Aptamers Mediating Tumour Cell Lysis. J Biol Chem 286: 21896-21905
Aptamer: TGF-ß1 (T18_1_3)
Aptamer sequence: CGCTCGGCTTCACGAGATTCGTGTCGTTGTGTCCTGTACCCGCCTTGACCAGTCACTCTAGAGCATCCGGACTG
Target: Transforming Growth Factor-ß1 (TGF-ß1)
Target chemistry: Protein
Affinity: 94 nM, 
Reference: Kang, Jonghoon, et al. "Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-??1 protein." Bioorganic & Medicinal Chemistry Letters, 18 (2008): 1835-1839.
Aptamer: CB-42
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGAAUUCCCGCGGCAGAAGCCCACCUGGCUUUGAACUCUAUGUUAUUGGGUGGGGGAAACUUAAGAAAACUACCACCCUUCAACAUUACCGCCCUUCAGCCUGCCAGCGCCCUGCAGCCCGGGAAGCUU
Target: Cibacron Blue 3GA
Affinity: Kd~600µM, 600000
Reference: https://pubmed.ncbi.nlm.nih.gov/1697402/
Aptamer: B4-25
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGAAUUCCCGCGGCGUUGGCCCAGGAUAAUAGGACGAAAUCCGAAAAAUCCGUACCCAACAUAGAACCCCCCCAGCGCUCACACGGACGCCCCAUUACGGCUAACCGAACGCCUGCAGCCCGGGAAGCUU
Target: Reactive Blue 4
Affinity: Kd<100µM, 100000
Reference: https://pubmed.ncbi.nlm.nih.gov/1697402/
Aptamer: wild type
Aptamer chemistry: ssRNA
Aptamer sequence: GAAUUGUGGUGUUGGCUCCCUAUAGUGAGUCGUAUUAAUAUUCCUUAGUUUUAUAGCCCAAUAACUCAGGCUCUUGAUUGGUUUUCAAUAGAGAUAUAAAAUUCUUUUCAUAG
Target: T4 DNA polymerase (gp43)
Affinity: Kd: 4.8 nM, 4,8
Reference: https://pubmed.ncbi.nlm.nih.gov/2200121/
Aptamer: major variant
Aptamer chemistry: ssRNA
Aptamer sequence: GAAUUGUGGUGUUGGCUCCCUAUAGUGAGUCGUAUUAAUAUUCCUUAGUUUUAUAGCCCAGCAACCUAGGCUCUUGAUUGGUUUUCAAUAGAGAUAUAAAAUUCUUUUCAUAG
Target: T4 DNA polymerase (gp43)
Affinity: Kd: 4.8 nM, 4,8
Reference: https://pubmed.ncbi.nlm.nih.gov/2200121/
Aptamer: 15 mer (colloquially known as Bock DNA Aptamer)
Aptamer chemistry: ssDNA
Aptamer sequence: GGTTGGTGTGGTTGG
Target: Thrombin (Sigma), Human
Affinity: Kd: 25-200 nM, 112,5
Reference: https://pubmed.ncbi.nlm.nih.gov/1741036/
Aptamer: ligand 1.1
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGCAUCAGACUUUUAAUCUGACAAUCAAGAAUUCCGUUUUCAGUCGGGAAAAACUGAACAAUCUAUGAAAGAAUUUUAUAUCUCUAUUGAAAC
Target: Human imunnodeficiency virus type 1 reverse transcriptase (HIV-1-RT)
Affinity: Kd: 5 nM, 5
Reference: https://pubmed.ncbi.nlm.nih.gov/1379730/
Aptamer: ligand 1.3a
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGCAUCAGACUUUUAAUCUGACAAUCAAGAAUAUCUUCCGAAGCCGAACGGGAAAACCGGCAUCUAUGAAAGAAUUUUAUCUCUAUUGAAAC
Target: Human imunnodeficiency virus type 1 reverse transcriptase (HIV-1-RT)
Affinity: Kd: 5 nM, 5
Reference: https://pubmed.ncbi.nlm.nih.gov/1379730/
Aptamer: 5A
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGCUCAGAAUAAACGCUCAAAUCUCCUCCCGUCGAAGCUAACCUGGCCACUUCGACAUGAGGCCCGGAUCCGGC
Target: Basic fibroblast growth factor (bFGF)
Affinity: Kd: 23 ± 3 nM, 23
Reference: https://pubmed.ncbi.nlm.nih.gov/7504300/
Aptamer: 7A
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGCUCAGAAUAAACGCUCAAUCGGCGAGCUAACCAAGACACUCGCUGCACUUCGACAUGAGGCCCGGAUCCGGC
Target: Basic fibroblast growth factor (bFGF)
Affinity: Kd: 5.0 ± 0.5 nM, 5
Reference: https://pubmed.ncbi.nlm.nih.gov/7504300/
Aptamer: 13A
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGCUCAGAAUAAACGCUCAAACCCGCGGCCUCCGAAGCUAACCAGGACACUUCGACAUGAGGCCCGGAUCCGGC
Target: Basic fibroblast growth factor (bFGF)
Affinity: Kd: 3.2 ± 0.5 nM, 3,2
Reference: https://pubmed.ncbi.nlm.nih.gov/7504300/
Aptamer: 14A
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGCUCAGAAUAAACGCUCAAUGGGUGCUAACCAGGACACACCCACGCUGUUUCGACAUGAGGCCCGGAUCCGGC
Target: Basic fibroblast growth factor (bFGF)
Affinity: Kd: 3.0 ± 0.5 nM, 3
Reference: https://pubmed.ncbi.nlm.nih.gov/7504300/
Aptamer: 21A
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGCUCAGAAUAAACGCUCAAUGGGUGCUUAACCAGGCCACACCCUGCUGUUUCGACAUGAGGCCCGGAUCCGGC
Target: Basic fibroblast growth factor (bFGF)
Affinity: Kd: 8.1 ± 0.8 nM, 8,1
Reference: https://pubmed.ncbi.nlm.nih.gov/7504300/
Aptamer: 12A
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGAUGCCUGUCGAGCAUGCUGGGGGCAACGCUACAGACAAGUGCACCCAACGUAGCUAAACAGCUUUGUCGACGGG
Target: Basic fibroblast growth factor (bFGF)
Affinity: Kd: exhibits biphasic binding, 0.51 ± 0.13 nM, 60 ± 52 nM, 0,51
Reference: https://pubmed.ncbi.nlm.nih.gov/7504300/
Aptamer: 26At
Aptamer chemistry: ssRNA
Aptamer sequence: GGUGAAGGCAACGUAUAGGCAAGCACACUUCACC
Target: Basic fibroblast growth factor (bFGF)
Affinity: Kd: ~0.19 ± 0.02 nM, 0,19
Reference: https://pubmed.ncbi.nlm.nih.gov/7504300/
Aptamer: 26A
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGAUGCCUGUCGAGCAUGCUGCGUCAGAAGGCAACGUAUAGGCAAGCACACGUAGCUAAACAGCUUUGUCGACGGG
Target: Basic fibroblast growth factor (bFGF)
Affinity: Kd: exhibits biphasic binding, 0.19 ± 0.02 nM, 49 ± 26 nM, 0,19
Reference: https://pubmed.ncbi.nlm.nih.gov/7504300/
Aptamer: 22B
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGAUGCCUGUCGAGCAUGCUGAGGGUAACGUACUGGCAAGCUCACCUCAGCGUAGCUAAACAGCUUUGUCGACGGG
Target: Basic fibroblast growth factor (bFGF)
Affinity: Kd: exhibits biphasic binding, 0.13 ± 0.03 nM, 510 ± 30 nM, 0,13
Reference: https://pubmed.ncbi.nlm.nih.gov/7504300/
Aptamer: 28B
Aptamer chemistry: ssRNA
Aptamer sequence: GGGAGAUGCCUGUCGAGCAUGCUGAGGGUAACGUAUAGUCAAGACACCUCAAGUGUAGCUAAACAGCUUUGUCGACGGG
Target: Basic fibroblast growth factor (bFGF)
Affinity: Kd: exhibits biphasic binding, 0.32 ± 0.07 nM, 140 ± 80 nM, 0,32
Reference: https://pubmed.ncbi.nlm.nih.gov/7504300/
Aptamer: 9
Aptamer chemistry: ssRNA
Aptamer sequence: GCUCUUGGGCGCAGCCUCAAUGAGGCUGGUGGUGCAAG
Target: Rev protein of HIV-1 (minimal Rev-binding element (RBE) found within the Rev Responsive Element (RRE))
Affinity: Kd: 1.9 ± 0.21*, nan
Reference: https://pubmed.ncbi.nlm.nih.gov/7505429/