Wisconsin Administrative Code › Department of Natural Resources › NR 100-199 - Environmental Protection - General › Chapter NR 105 - Surface Water Quality Criteria And Secondary Values For Toxic Substances › Section NR 105.09 - Human cancer criteria

Current through June 24, 2024
(1) The human cancer criterion (HCC) is the
				maximum concentration of a substance or mixture of substances established to
				protect humans from an unreasonable incremental risk of cancer resulting from
				contact with or ingestion of surface waters of the state and from ingestion of
				aquatic organisms taken from surface waters of the state. Human cancer criteria
				are derived for those toxic substances which are carcinogens as defined in s.
				NR 105.03 (13).
(2) For any single
				carcinogen or any mixture of carcinogens the incremental cancer risk from
				exposure to surface waters and aquatic organisms taken from surface waters may
				not exceed one in 100,000. The combined cancer risk of individual carcinogens
				in a mixture is assumed to be additive unless an alternate model is supported
				by credible scientific evidence.
(3) Human cancer criteria are listed in Table
				9. Criteria for the same substance may be different depending on the surface
				water classification, due to the lipid value of representative fish, a
				component of the BAF, and whether or not the water may be a source of drinking
				water. Further application of these criteria to protect drinking water and
				downstream uses in the Great Lakes system shall be according to s. NR 106.06
				(1).
Table 9.
Human Cancer Criteria
(ug/L unless specified
				  otherwise1)
Public Water
								Supply
Non-Public Water
								Supply
Substance
Warm Water Sport Fish Communities
Cold Water4
								  Communities
Warm Water Forage, Limited Forage, and Warm Water
								Sport Fish Communities
Cold Water Communities
Limited Aquatic Life
1.
Acrylonitrile
0.57
0.45
4.6
1.5
130
2.
Arsenic
0.2
0.2
13.3
13.3
40
3.
*alpha-BHC
0.012
0.0037
0.013
0.0039
11
4.
*gamma-BHC (lindane)
0.052
0.018
0.064
0.019
54
5.
*BHC, technical grade
0.038
0.013
0.047
0.014
39
6.
Benzene2
5
5
140
45
1300
7.
Benzidine (ng/L)
1.5
1.5
81
55
300
8.
Beryllium
0.054
0.054
0.33
0.33
16
9.
Bis(2-chloroethyl) ether
0.31
0.29
7.6
3.0
64
10.
Bis(chloromethyl) ether (ng/L)
1.6
1.6
96
79
320
11.
Carbon tetrachloride
2.5
2.1
29
9.5
540
12.
*Chlordane (ng/L)
0.41
0.12
0.41
0.12
54000
13.
Chloroethene (vinyl chloride)
0.18
0.18
10
6.8
37
14.
Chloroform (trichloromethane)
55
53
1960
922
11200
15.
*4,4'-DDT (ng/L)
0.22
0.065
0.22
0.065
206000
16.
1,4-Dichlorobenzene
14
12
163
54
2940
17.
3,3'-Dichlorobenzidine
0.5
0.3
1.3
0.4
140
18.
1,3-Dichloropropene
3.4
3.4
173
108
700
19.
1,2-Dichloroethane
3.8
3.8
217
159
770
20.
Dichloromethane2
								(methylene chloride)
5
5
2700
2100
9600
21.
*Dieldrin (ng/L)
0.0091
0.0027
0.0091
0.0027
4400
22.
2,4-Dinitrotoluene
0.51
0.48
13
5.3
110
23.
1,2-Diphenylhydrazine
0.38
0.31
3.3
1.04
88
24.
Halomethanes3
55
53
1960
922
11200
25.
*Hexachlorobenzene (ng/L)
0.73
0.22
0.73
0.22
44000
26.
*Hexachlorobutadiene
0.59
0.19
0.69
0.2
910
27.
Hexachloroethane
7.7
2.9
11
3.3
5000
28.
N-Nitrosodiethylamine (ng/L)
2.3
2.3
150
140
460
29.
N-Nitrosodimethylamine
0.0068
0.0068
0.46
0.46
1.4
30.
N-Nitrosodi-n-butylamine
0.063
0.062
2.5
1.3
13
31.
N-Nitrosodiphenylamine
44
23
116
34
13000
32.
N-Nitrosopyrrolidine
0.17
0.17
11
11
34
33.
*Polychlorinated biphenyls (ng/L)
0.01
0.003
0.01
0.003
9100
34.
*2,3,7,8-Tetrachlorodibenzo-p-dioxin
								(pg/L)
0.014
0.0041
0.014
0.0041
930
35.
1,1,2,2-Tetrachloroethane
1.7
1.6
52
22
350
36.
Tetrachloroethene2
5.0
4.6
46
15
1300
37.
*Toxaphene (ng/L)
0.11
0.034
0.14
0.034
63600
38.
1,1,2-Trichloroethane2
5.0
5.0
195
87
1200
39.
Trichloroethene2
5
5
539
194
6400
40.
2,4,6-Trichlorophenol
29
24
300
97
6400
* Indicates substances that are BCCs.
1 A human cancer criterion
				  expressed in micrograms per liter (ug/L), nanograms per liter (ng/L) or
				  picograms per liter (pg/L) can be converted to milligrams per liter (mg/L) by
				  dividing the criterion by 1000, 1,000,000 or 1,000,000,000,
				  respectively.
2 For this substance the human
				  cancer criteria for public water supply receiving water classifications equal
				  the maximum contaminant level pursuant to s. NR 105.09 (4) (b).
3 Human cancer criteria for
				  halomethanes are applicable to any combination of the following chemicals:
				  bromomethane (methyl bromide), chloromethane (methyl chloride), tribromomethane
				  (bromoform), bromodichloromethane (dichloromethyl bromide),
				  dichlorodifluoromethane (fluorocarbon 12) and trichlorofluoromethane
				  (fluorocarbon 11).
4 For BCCs, these criteria apply
				  to all waters of the Great Lakes system.
(4) To derive human cancer criteria for
				substances not included in Table 9 the following methods shall be used:
(a) The human cancer criterion shall be
				calculated as follows:
HCC= RAD x 70 kg / WH +
				  (FH x BAF)
Where: HCC = Human cancer criterion in milligrams per liter
				  (mg/L).
RAD = Risk associated dose in milli- grams toxicant per
				  kilogram body weight per day (mg/kg- d) that is associated with a lifetime
				  incremental cancer risk equal to one in 100,000 as derived in sub. (5).
70 kg = Average weight of an adult male in kilograms (kg).
WH = Average per capita daily water
				  consumption of 2 liters per day (L/d) for surface waters classified as public
				  water supplies or, for other surface waters, 0.01 liters per day (L/d) for
				  exposure through contact or ingestion of small volumes of water during swimming
				  or during other recreational activities.
FH = Average per capita daily con-
				  sumption of sport-caught fish by Wisconsin anglers equal to 0.02 kilograms per
				  day (kg/d).
BAF = Aquatic life bioaccumulation factor with units of liter
				  per kilogram (L/kg) as derived in s. NR 105.10.
(b) For surface waters classified as public
				water supplies, if the human cancer criterion for a toxic substance as
				calculated in par. (a) exceeds the maximum contaminant level (MCL) for that
				substance as specified in ch. NR 809 or the July 8, 1987 Federal Register (52
				FR 25690), the MCL shall be used as the human cancer criterion.