New Jersey Administrative Code › Title 7 - ENVIRONMENTAL PROTECTION › Chapter 26D - REMEDIATION STANDARDS › Appendix 11

Current through Register Vol. 56, No. 14, July 15, 2024
TOXICITY FACTORS USED IN THE DEVELOPMENT OF THE REMEDIATION STANDARDS
Table 1-Soil Ingestion-Dermal Toxicity Factors
Contaminant
CAS No.
Soil Ingestion-dermal Recommendation
Soil Ingestion-dermal Toxicity Factor(s)
Acenaphthene
83-32-9
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1994) 0.06 mg/kg-day ABS 0.13
Acetone
67-64-1
IRIS RfD
IRIS RfD (2003) 0.9 mg/kg-day
Acetophenone
98-86-2
IRIS RfD
IRIS RfD (1989) 0.1 mg/kg-day
Aldrin
309-00-2
IRIS Slope Factor (SF) RfD
IRIS SF (1993) 17 (mg/kg-day)-1 IRIS RfD (1988) 0.00003 mg/kg-day
Aluminum
7429-90-5
PPRTV RfD
PPRTV RfD (2006) 1.0 mg/kg-day
Anthracene
120-12-7
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1993) 0.3 mg/kg-day ABS 0.13
Antimony
7440-36-0
IRIS RfD with a gastrointestinal absorption fraction (GIABS)
IRIS RfD (1991) 0.0004 mg/kg-day GIABS 0.15
Arsenic
7440-38-2
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS)
IRIS SF (1998) 1.5 (mg/kg-day)-1 IRIS RfD (1993) 0.0003 mg/kg-day ABS 0.03
Atrazine
1912-24-9
IRIS RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor
IRIS RfD (1993) 0.035 mg/kg-day ABS 0.1 Group C carcinogen factor 10
Barium
7440-39-3
IRIS RfD with a gastrointestinal absorption fraction (GIABS)
IRIS RfD (2005) 0.2 mg/kg-day GIABS 0.07
Benzaldehyde
100-52-7
PPRTV Slope Factor (SF) IRIS RfD
PPRTV SF (2015) 4E-03 (mg/kg-day)-1 IRIS RfD (1988) 0.1 mg/kg-day
Benzene
71-43-2
NJDWQI Slope Factor (SF) IRIS RfD1
NJDWQI SF (1994) 0.23 (mg/kg-day)-1 IRIS RfD (2003) 0.004 mg/kg-day
Benzo(a)anthracene
56-55-3
IRIS Slope Factor (SF) (benzo(a)pyrene -adjusted for benzo(a) pyrene) with a dermal absorption fraction (ABS)
IRIS SF (2017) 1.0E-01(mg/kg-day)-1 (adjusted for benzo (a)anthracene) ABS 0.13
Benzo(a)pyrene
50-32-8
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS)
IRIS SF (2017) 1.0E +00 (mg/kg-day)-1
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (2017) 3.0E-04 mg/kg-day ABS 0.13
IRIS Slope Factor (SF) (benzo(a)pyrene -
IRIS SF (2017) 1.0E-01 (mg/kg-
Benzo(b)fluoranthene
205-99-2
adjusted for benzo(b) fluoranthene) with a dermal absorption fraction (ABS)
day)-1 (adjusted for benzo (b)fluoranthene) ABS 0.13
Benzo(k)fluoranthene
207-08-9
IRIS Slope Factor (SF) (benzo(a)pyrene -adjusted for benzo(k) fluoranthene) with a dermal absorption fraction (ABS)
IRIS SF (2017) 1.0E-02(mg/kg-day)-1 (adjusted for benzo(k) fluoranthene) ABS 0.13
Beryllium
7440-41-7
IRIS RfD with a gastrointestinal absorption fraction (GIABS)
IRIS RfD (1998) 0.002 mg/kg-day GIABS 0.007 IRIS SF (2013)
1,1'-Biphenyl
92-52-4
IRIS Slope Factor (SF) IRIS RfD
0.008 (mg/kg-day)- 1 IRIS RfD (2013) 0.5 mg/kg-day
Bis(2-chloroethoxy) methane
111-91-1
PPRTV RfD with a dermal absorption fraction (ABS)
PPRTV RfD (2006) 0.003 mg/kg-day ABS 0.1
Bis(2-chloroethyl) ether
111-44-4
IRIS Slope Factor (SF)
IRIS SF (1994) 1.1 (mg/kg-day)-1
Bis(2-ethylhexyl) phthalate
117-81-7
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS)
IRIS SF (1993) 0.014 (mg/kg-day)-1 IRIS RfD (2013) 0.02 mg/kg-day ABS 0.1
Bromodichloromethane
75-27-4
IRIS Slope Factor (SF) IRIS RfD
IRIS SF (1993) 0.062 (mg/kg-day)-1 IRIS RfD (1991) 0.02 mg/kg-day IRIS SF (1991)
Bromoform
75-25-2
IRIS Slope Factor (SF) IRIS RfD
0.0079 (mg/kg-day)-1 IRIS RfD (1991) 0.02 mg/kg-day
Bromomethane
74-83-9
IRIS RfD
IRIS RfD (1991) 0.0014 mg/kg-day
2-Butanone
78-93-3
IRIS RfD2
IRIS RfD (2003) 0.6 mg/kg-day
Butylbenzylphthalate
85-68-7
PPRTV Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor
PPRTV SF (2002) 0.0019 (mg/kg-day)-1 IRIS RfD (2013) 0.2 mg/kg-day ABS 0.1 Group C carcinogen factor 10
Cadmium
7440-43-9
IRIS RfD with a dermal absorption fraction (ABS) and gastrointestinal absorption fraction (GIABS)
IRIS RfD (1994) 0.001 mg/kg-day ABS 0.001 GIABS 0.025
Caprolactam
105-60-2
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1988) 0.5 mg/kg-day ABS 0.1
Carbon disulfide
75-15-0
No ingestion-based toxicity factors are available
None
Carbon tetrachloride
56-23-5
NJDWQI Slope Factor (SF) IRIS RfD
NJDWQI SF (1994) 0.091 (mg/kg-day)-1 IRIS RfD (2011) 0.004 mg/kg-day
Chlordane (alpha plus gamma mix
ture) 57-74-9
NJDWQI Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) PPRTV Slope Factor (SF) with a dermal absorption
NJDWQI SF (2001) 2.3 (mg/kg-day)-1 IRIS RfD (1998) 0.0005 mg/kg-day ABS 0.04 PPRTV SF (2008) 0.2 (mg/kg-day)-1
4-Chloroaniline
106-47-8
fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1995) 0.004 mg/kg-day ABS 0.1
Chlorobenzene
108-90-7
NJDWQI RfD
NJDWQI RfD (1994) 0.0065 mg/kg-day
Chloroethane
75-00-3
No ingestion-based toxicity factors are available
None
Chloroform
67-66-3
IRIS RfD3
IRIS RfD (2001) 0.01 mg/kg-day
Chloromethane
74-87-3
No ingestion-based toxicity factors are available
None
2-Chloronaphthalene
91-58-7
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1990) 0.08 mg/kg-day ABS 0.13
2-Chlorophenol
95-57-8
IRIS RfD
IRIS RfD (1993) 0.005 mg/kg-day
Chrysene
218-01-9
IRIS Slope Factor (SF) (benzo(a)pyrene-adjusted for chrysene) with a dermal absorption fraction (ABS)
IRIS SF (2017) 1.0E-03 (mg/kg-day)-1 (adjusted for chrysene) ABS 0.13
Cobalt
7440-48-4
PPRTV RfD
PPRTV RfD (2008) 0.0003 mg/kg-day
Copper
7440-50-8
HEAST RfD
HEAST RfD (1997) 0.04 mg/kg-day
Cyanide
57-12-5
IRIS RfD
IRIS RfD (2010) 0.0006 mg/kg-day
Cyclohexane
110-82-7
No ingestion-based toxicity factors are available
None
4,4'-DDD
72-54-8
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS)
IRIS SF (1988) 0.24 (mg/kg-day)-1 ABS 0.1
4,4'-DDE
72-55-9
IRIS SF
4,4'-DDT
50-29-3
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS)
IRIS SF (1991) 0.34 (mg/kg-day)-1 IRIS RfD (1996) 0.0005 mg/kg-day ABS 0.03
Dibenz(a,h)anthracene
53-70-3
IRIS Slope Factor (SF) (benzo(a)pyrene-adjusted for dibenz(a,h) anthracene) with a dermal absorption fraction (ABS)
IRIS SF (2017) 1.0E+00 (mg/kg-day)-1 (adjusted for dibenz(a,h) anthracene) ABS 0.13
Dibromochloromethane
124-48-1
IRIS Slope Factor (SF) IRIS RfD and a Group C carcinogen factor
IRIS SF (1992) 0.084 (mg/kg-day)-1 IRIS RfD (1991) 0.02 mg/kg-day Group C carcinogen factor 10 PPRTV SF (2006)
1,2-Dibromo-3-chloropropane
96-12-8
PPRTV Slope Factor (SF) PPRTV RfD
0.8 (mg/kg-day)-1 PPRTV RfD (2006) 0.0002 mg/kg-day IRIS SF (2004)
1,2-Dibromoethane
106-93-4
IRIS Slope Factor (SF) IRIS RfD
2.0 (mg/kg-day)-1 IRIS RfD (2004) 0.009 mg/kg-day NJDWQI RfD
1,2-Dichlorobenzene
95-50-1
NJDWQI RfD
(1994) 0.086 mg/kg-day NJDWQI RfD
1,3-Dichlorobenzene
541-73-1
NJDWQI RfD
(1994) 0.086 mg/kg-day NJDWQI RfD (1994)
NJDWQI RfD with a
0.01 mg/kg-day
1,4-Dichlorobenzene
106-46-7
Group C carcinogen
(RfD includes
factor4
Group C Carcinogen factor adjustment of 10)
3,3'-Dichlorobenzidine
91-94-1
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS)
IRIS SF (1993) 0.45 (mg/kg-day)-1 ABS 0.1
Dichlorodifluoromethane
75-71-8
IRIS RfD
IRIS RfD (1995) 0.2 mg/kg-day
CalEPA SF (1992)
1,1-Dichloroethane
75-34-3
CalEPA Slope Factor (SF) PPRTV RfD5
0.0057 (mg/kg- day)-1 PPRTV RfD (2006) 0.2 mg/kg-day
1,2-Dichloroethane
107-06-2
NJDWQI Slope Factor (SF)6
NJDWQI SF (1994) 0.12 (mg/kg-day)-1
NJDWQI RfD (1994)
NJDWQI RfD with a
0.00014 mg/kg-day
1,1-Dichloroethene
75-35-4
Group C carcinogen
(RfD includes
factor
Group C Carcinogen factor adjustment of 10)
NJDWQI RfD
cis-1,2-Dichloroethene
156-59-2
NJDWQI RfD
(1994) 0.01 mg/kg-day NJDWQI RfD
trans-1,2-Dichloroethene
156-60-5
NJDWQI RfD
(1994) 0.017 mg/kg-day
2,4-Dichlorophenol
120-83-2
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1988) 0.003 mg/kg-day ABS 0.1 PPRTV SF (2016)
1,2-Dichloropropane
78-87-5
PPRTV Slope Factor (SF) PPRTV RfD
0.037 (mg/kg-day)-1 PPRTV RfD (2016) 0.04 mg/kg-day IRIS SF (2000)
1,3-Dichloropropene (cis and trans)
542-75-6
IRIS Slope Factor (SF) IRIS RfD
0.1 (mg/kg-day)-1 IRIS RfD (2000) 0.03 mg/kg-day
Dieldrin
60-57-1
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS)
IRIS SF (1993) 16 (mg/kg-day)-1 IRIS RfD (1990) 0.00005 mg/kg-day ABS 0.1
Diethylphthalate
84-66-2
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1993) 0.8 mg/kg-day ABS 0.1
2,4-Dimethylphenol
105-67-9
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1990) 0.02 mg/kg-day ABS 0.1
Di-n-butylphthalate
84-74-2
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1990) 0.1 mg/kg-day ABS 0.1
2,4-Dinitrophenol
51-28-5
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1991) 0.002 mg/kg-day ABS 0.1
2,4-Dinitrotoluene /2,6-Dinitrotoluene (mixture)
25321-146
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS)
IRIS SF (1990) 0.68 (mg/kg-day)-1 ABS 0.1
Di-n-octylphthalate
117-84-0
PPRTV RfD with a dermal absorption fraction (ABS)
PPRTV RfD (2012) 0.01 mg/kg-day ABS 0.1 IRIS SF (2013)
1,4-Dioxane
123-91-1
IRIS Slope Factor (SF) IRIS RfD
0.1 (mg/kg-day)-1 IRIS RfD (2010) 0.03 mg/kg-day
Endosulfan I and Endosulfan II
115-29-7
IRIS RfD
Endrin
72-20-8
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1991) 0.0003 mg/kg-day ABS 0.1
Ethylbenzene
100-41-4
IRIS RfD7
IRIS RfD (1991) 0.1 mg/kg-day
Extractable Petroleum Hydrocarbons (EPH) (Category 1)
various
N.J.A.C. 7:26D-Appendix 2, Equation 5
See Table 1a-EPH Toxicity (below)
Extractable Petroleum Hydrocarbons (EPH) (Category 2)
various
N.J.A.C. 7:26D-Appendix 2, Equation 5
See Table 1a-EPH Toxicity (below)
Fluoranthene
206-44-0
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1993) 0.04 mg/kg-day ABS 0.13
Fluorene
86-73-7
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1990) 0.04 mg/kg-day ABS 0.13
alpha-HCH (alpha-BHC)
319-84-6
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) ATSDR RfD with a dermal absorption fraction (ABS)
IRIS SF (1993) 6.3 (mg/kg-day)-1 ATSDR RfD (2013) 0.008 mg/kg-day ABS 0.1
beta-HCH (beta-BHC)
319-85-7
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) and Group C carcinogen factor
IRIS SF (1993) 1.8 (mg/kg-day)-1 ABS 0.1 Group C carcinogen factor 10
Heptachlor
76-44-8
IRIS Slope Factor (SF) IRIS RfD
Heptachlor epoxide
1024-57-3
IRIS Slope Factor (SF) IRIS RfD
Hexachlorobenzene
118-74-1
IRIS Slope Factor (SF) IRIS RfD
IRIS Slope Factor (SF)
IRIS SF (1991) 0.078 (mg/kg-day)-1
Hexachloro-1,3-butadiene
87-68-3
PPRTV RfD with a Group C carcinogen factor
PPRTV RfD (2007) 0.001 mg/kg-day Group C carcinogen factor 10
Hexachlorocyclopentadiene
77-47-4
IRIS RfD
IRIS Slope Factor (SF)
IRIS SF (2011) 0.04 (mg/kg-day)-
Hexachloroethane
67-72-1
IRIS RfD
n-Hexane
110-54-3
No ingestion-based toxicity factors are available17
None
2-Hexanone
591-78-6
IRIS RfD IRIS Slope Factor (SF) (benzo(a)pyrene--
IRIS RfD (2009) 0.005 mg/kg-day IRIS SF (2017) 1.0E-01(mg/kg-
Indeno(1,2,3-cd) pyrene
193-39-5
adjusted for indeno (1,2,3-cd)pyrene) with a dermal absorption
day)-1 (adjusted for indeno(1,2,3-cd) pyrene)
fraction (ABS). IRIS Slope Factor (SF)
ABS 0.13
Isophorone
78-59-1
with a dermal absorption fraction (ABS)
IRIS SF (1992) 0.00095 (mg/kg-
IRIS RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor
day)-1 IRIS RfD (2003) 0.2 mg/kg-day ABS 0.1 Group C carcinogen factor 10
Isopropylbenzene
98-82-8
IRIS RfD USEPA IEUBK model for
IRIS RfD (1997) 0.1 mg/kg-day IEUBK (1994)
Lead
7439-92-1
children USEPA ALM for adults
Children ALM (1996) Adults
CalEPA Slope Factor (SF) with a
1.1 (mg/kg-day)-1
Lindane (gamma-HCH) (gamma-BHC)
58-89-9
dermal absorption fraction (ABS)
IRIS RfD (1988) 0.0003 mg/kg-day
IRIS RfD with a dermal absorption fraction (ABS)
ABS 0.04 EPA RSL RfD
Manganese
7439-96-5
EPA RSL RfD
(2018) 0.024 mg/kg-day
Mercury
7439-97-6
IRIS RfD with a gastrointestinal absorption fraction (GIABS)
IRIS RfD (1995) 0.0003 mg/kg-day GIABS 0.07
Methoxychlor
72-43-5
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1991) 0.005 mg/kg-day ABS 0.1
Methyl acetate
79-20-9
HEAST RfD
HEAST RfD (1997) 1.0 mg/kg-day
NJDWQI Slope Factor
NJDWQI SF (1994) 0.014 (mg/kg-day)-
Methylene chloride
75-09-2
(SF) IRIS RfD
1 IRIS RfD (2011) 0.006 mg/kg-day
2-Methylnaphthalene
91-57-6
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (2003) 0.004 mg/kg-day ABS 0.13
4-Methyl-2-pentanone
108-10-1
No ingestion-based toxicity factors are available
None
2-Methylphenol
95-48-7
IRIS RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor
IRIS RfD (2008) 0.05 mg/kg-day ABS 0.1 Group C carcinogen factor 10
4-Methylphenol
106-44-5
ATSDR RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor
ATSDR RfD (2013) 0.1 mg/kg-day ABS 0.1 Group C carcinogen factor 10
NJDWQI RfD (1994)
NJDWQI RfD with a
0.01 mg/kg-day
Methyl tert-butyl ether (MTBE)
1634-04-4
Group C carcinogen factor8
(RfD includes Group C Carcinogen factor adjustment of 10)
Naphthalene
91-20-3
NJDWQI RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor
NJDWQI RfD (1994) 0.041 mg/kg-day ABS 0.13 (RfD includes Group C Carcinogen factor adjustment of 10)
Nickel
7440-02-0
IRIS RfD with a gastrointestinal absorption fraction (GIABS)
IRIS RfD (1996) 0.02 mg/kg-day GIABS 0.04 IRIS SF (2009)
4-Nitroaniline
100-01-6
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) PPRTV RfD with a dermal absorption fraction (ABS)
0.02 (mg/kg-day)-1 PPRTV RfD (2009) 0.004 mg/kg-day 0.0049 (mg/kg-day)-1 ABS 0.1
Nitrobenzene
98-95-3
IRIS RfD
IRIS RfD (2009) 0.002 mg/kg-day
N-Nitroso-di-n-propylamine
621-64-7
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS)
IRIS SF (1993) 7.0 (mg/kg-day)-1 ABS 0.1
N-Nitrosodiphenylamine
86-30-6
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS)
IRIS SF (1993) 0.0049 (mg/kg-day)-1 ABS 0.1
2,2'-Oxybis(1-choloropropane)
108-60-1
IRIS RfD
IRIS RfD (1991) 0.04 mg/kg-day
Pentachlorophenol
87-86-5
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS)
IRIS SF (2010) 0.4 (mg/kg-day)-1 IRIS RfD (2010) 0.005 mg/kg-day ABS 0.25
Phenol
108-95-2
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (2002) 0.3 mg/kg-day ABS 0.1
Polychlorinated biphenyls (PCBs)
1336-36-3
NJDWQI Slope Factor (SF) with a dermal absorption fraction (ABS)
NJDWQI SF (1994) 2 (mg/kg-day)-1 ABS 0.14
Pyrene
129-00-0
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1993) 0.03 mg/kg-day ABS 0.13
Selenium
7782-49-2
IRIS RfD
IRIS RfD (1991) 0.005 mg/kg-day
Silver
7440-22-4
IRIS RfD with a gastrointestinal absorption fraction (GIABS)
IRIS RfD (1996) 0.005 mg/kg-day GIABS 0.04
Styrene
100-42-5
IRIS RfD
IRIS RfD (1990) 0.2 mg/kg-day
NJDEP RfD (1997) 0.018 mg/kg-day
Tertiary butyl alcohol (TBA)
75-65-0
NJDEP RfD with a Group C carcinogen factor
(RfD includes Group C Carcinogen factor adjustment of 10)
1,2,4,5-Tetrachlorobenzene
95-94-3
IRIS RfD
2,3,7,8-Tetrachlorodibenzo-p-dioxin
1746-01-6
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (2012) 7E-10 mg/kg-day ABS 0.03 IRIS SF (2010)
1,1,2,2-Tetrachloroethane
79-34-5
IRIS Slope Factor (SF) IRIS RfD9
0.2 (mg/kg-day)-1 IRIS RfD (2010) 0.02 mg/kg-day IRIS SF (2012)
Tetrachloroethene (PCE)
127-18-4
IRIS Slope Factor (SF) IRIS RfD10
0.0021 (mg/kg-day)-1 IRIS RfD (2012) 0.006 mg/kg-day
2,3,4,6-Tetrachlorophenol
58-90-2
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1992) 0.03 mg/kg-day ABS 0.1
Toluene
108-88-3
IRIS RfD
IRIS RfD (2005) 0.08 mg/kg-day
Toxaphene
8001-35-2
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS)
IRIS SF (1991) 1.1 (mg/kg-day)-1 ABS 0.1 IRIS RfD (1996)
1,2,4-Trichlorobenzene
120-82-1
IRIS RfD11
0.01 mg/kg-day
1,1,1-Trichloroethane
71-55-6
IRIS RfD12
IRIS RfD (2007) 2 mg/kg-day IRIS SF (2011)
Trichloroethene (TCE)
79-01-6
IRIS Slope Factor (SF)14 IRIS RfD
0.046 (mg/kg-day)-1 IRIS RfD (2011) 0.0005 mg/kg-day
Trichlorofluoromethane
75-69-4
IRIS RfD
IRIS RfD (1992) 0.3 mg/kg-day
2,4,5-Trichlorophenol
95-95-4
IRIS RfD with a dermal absorption fraction (ABS)
IRIS RfD (1988) 0.1 mg/kg-day ABS 0.1
2,4,6-Trichlorophenol
88-06-2
IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) PPRTV RfD with a dermal absorption fraction (ABS)
IRIS SF (1994) 0.011 (mg/kg-day)-1 PPRTV RfD (2007) 0.001 mg/kg-day ABS 0.1
1,1,2-Trichloro-1,2,2-trifluoroethane
76-13-1
No ingestion-based toxicity factors are available15
None
1,2,4-Trimethylbenzene
95-63-6
IRIS RfD
IRIS RfD (2016) 0.01 mg/kg-day
Vanadium
7440-62-2
EPA RSL RfD with a gastrointestinal absorption fraction
EPA RSL RfD (2018) 0.005 mg/kg-day GIABS 0.026
Vinyl Chloride
75-01-4
IRIS Slope Factor (SF)
IRIS SF (2000) 0.72 (mg/kg-day)-
IRIS RfD16
1 IRIS RfD (2000) 0.003 mg/kg-day NJDWQI RfD
Xylenes
1330-20-7
NJDWQI RfD
(1994) 0.15 mg/kg-day
Zinc
7440-66-6
IRIS RfD
IRIS RfD (2005) 0.3 mg/kg-day
Table 1a--EPH Toxicity
Applies to both:
EPH - Category 1 (Number 2 Heating Oil/Diesel Fuel)
EPH - Category 2 (Heavier petroleum products)
Note: EPH excludes lighter petroleum products including gasoline and mineral spirits
Effective Carbon Range Aliphatics
Surrogate
Toxicity Factor
Toxicity Factor Reference Source
9 - 12
PHC Mixture
RfD 0.10 mg/kg-day ABS 0.1
Canada 2000 and MADEP 2003
12 - 16
PHC Mixture
RfD 0.10 mg/kg-day ABS 0.1
Canada 2000 and MADEP 2003
16 - 21
White Mineral Oil
RfD 2.0 mg/kg-day ABS 0.1
TPHCWG 1997 and MADEP 2003
21 - 40
White Mineral Oil
RfD 2.0 mg/kg-day ABS 0.1
TPHCWG 1997 and MADEP 2003
Effective Carbon Range Aromatics
Surrogate
Toxicity Factor
Toxicity Factor Reference Source
10 - 12
Naphthalene
RfD 0.041 mg/kg-day ABS 0.13
NJDWQI (1994)
12 - 16
Acenaphthene
RfD 0.06 mg/kg-day ABS 0.13
IRIS (1994)
16 - 21
Fluorene
RfD 0.04 mg/kg-day ABS 0.13
IRIS (1990)
21 - 36
Fluoranthene
RfD 0.04 mg/kg-day
IRIS (1993)
1 Both the NJDWQI slope factor and IRIS RfD for benzene are based on a route to route conversion of an inhalation study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.
2 Although a NJDWQI RfD for 2-butanone exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route to route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route to route conversion of toxicity factors.
3 Although a CalEPA slope factor for chloroform exists, the USEPA believes there is a threshold effect for cancer. As such, an RfD based soil remediation standard is protective of both cancer and non-cancer health endpoints.
4 Although a CalEPA Slope Factor for 1,4-dichlorobenzene exists, there are questions about the study used to develop the slope factor. As such, the Department has decided not to develop an ingestion-dermal soil remediation standard for 1,4-dichlorobenzene using this slope factor.
5 Although a NJDWQI RfD for 1,1-dichloroethane exists, it is based on an inhalation route to route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route to route conversion of toxicity factors.
6 Although a PPRTV RfD for 1,2-dichloroethane exists, it is listed as an appendix value. PPRTV appendix values are based on a study(s) that has flaws as determined by the USEPA. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop soil remediation standards.
7 Although a CalEPA slope factor for ethylbenzene exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route-to-route conversion of toxicity factors.
8 Although a CalEPA slope factor for methyl tert-butyl ether exists, there are questions about the study used to develop the slope factor. As such, the Department has decided not to develop an ingestion-dermal soil remediation standard for methyl tert-butyl ether using this slope factor.
9Although an NJDWQI RfD for 1,1,2,2-tetrachloroethane exists, the Department has decided to use an IRIS RfD to develop a non-cancer-based ingestion-dermal soil remediation standard as the IRIS RfD is based on a newer toxicology assessment.
10 Although an NJDWQI slope factor for tetrachloroethene exists, the Department has decided that the existing IRIS Slope Factor is a scientifically better toxicity value to develop a cancer-based ingestion-dermal soil remediation standard. The IRIS slope factor uses the newest PBPK models (extrapolating from an inhalation unit risk factor to an oral slope factor). An ingestion-dermal soil remediation standard for tetrachloroethene can also be developed using an IRIS RfD. The RfD uses the newest PBPK models (extrapolating from an inhalation RfC to oral RfD).
11Although an NJDWQI RfD for 1,2,4-trichlorobenzene exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route-to-route conversion of toxicity factors. In addition, a USEPA PPRTV slope factor for 1,2,4-trichlorobenzene is available, however the Slope Factor is based on a controversial mouse liver tumor study that many researchers have dismissed. The Department has decided not to develop an ingestion-dermal soil remediation standard based on the PPRTV slope factor.
12 Although an NJDWQI RfD for 1,1,1-trichloroethane exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with USEPA policy concerning route-to-route conversion of toxicity factors.
13 Although an NJDWQI slope factor for 1,1,2-trichloroethane exists, the Department determined that the IRIS slope factor is a scientifically better toxicity value to develop a cancer-based ingestion-dermal soil remediation standard.
14 Although an NJDWQI slope factor for trichloroethene exists, the Department determined that the IRIS slope factor is a scientifically better toxicity value to develop a cancer-based ingestion-dermal soil remediation standard. The IRIS slope factor uses the newest PBPK models (extrapolating from an inhalation unit risk factor to an oral slope factor).
15 Although an IRIS RfD for 1,1,2-Trichloro-1,2,2-trifluoroethane exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with USEPA policy concerning route-to-route conversion of toxicity factors.
16 Although an NJDWQI slope factor exists for vinyl chloride, the Department determined that the IRIS slope factor is a scientifically better toxicity value to develop a cancer-based ingestion-dermal soil remediation standard.
*17 Although an NJDWQI RfD (1994) for n-hexane exists, it is based on an inhalation route to route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route to route conversion of toxicity factors. This policy conforms with USEPA policy concerning route to route conversion of toxicity factors.
Table 2-Soil Inhalation Toxicity Factors
Contaminant
CAS No.
Soil Inhalation Recommendation
Soil Inhalation Toxicity Factor(s)
Acenaphthene
83-32-9
No inhalation-based toxicity factors are available18
None
Acetone
67-64-1
No inhalation-based toxicity factors are available1
None
No inhalation-based
Acetophenone
98-86-2
toxicity factors are available2
None
Aldrin
309-00-2
No inhalation-based toxicity factors are available17
None
Aluminum
7429-90-5
PPRTV RfC
PPRTV RfC (2006) 5E-03 mg/m3
Anthracene
120-12-7
No inhalation-based toxicity factors are available18
None
Antimony
7440-36-0
No inhalation-based toxicity factors are available19
None
Arsenic
7440-38-2
IRIS IUR
IRIS IUR (1998) 4.3E-03 (ug/m3)-1
No inhalation-based
Atrazine
1912-24-9
toxicity factors are available
None
Barium
7440-39-3
HEAST RfC
HEAST RfC (1997) 5E-04 mg/m3
Benzaldehyde
100-52-7
No inhalation-based toxicity factors are available
None
Benzene
71-43-2
IRIS IUR IRIS RfC
IRIS IUR (2000) 7.8E-06 (ug/m3)-1 IRIS RfC (2003) 3E-02 mg/m3
Benzo(a)anthracene
56-55-3
IRIS IUR (benzo(a) pyrene) adjusted for benzo(a)anthracene
IRIS IUR (2017) 6.0E-05 (ug/m3)-1 v (adjusted for benzo(a) anthracene)
Benzo(a)pyrene
50-32-8
IRIS IUR IRIS RfC
IRIS IUR (2017) 6.0E-04 (ug/m3)-1 IRIS RfC (2017) 2.0E-06 mg/m3
Benzo(b)fluoranthene
205-99-2
IRIS IUR (benzo(a) pyrene) adjusted for benzo(b)fluoranthene
IRIS IUR (2017) 6.0E-05 (ug/m3)-1 (adjusted for benzo (b)fluoranthene)
Benzo(k)fluoranthene
207-08-9
IRIS IUR (benzo(a) pyrene) adjusted for benzo(k) fluoranthene
IRIS IUR (2017) 6.0E-06 (ug/m3)-1 (adjusted for benzo (k) fluoranthene) IRIS IUR (1998)
Beryllium
7440-41-7
IRIS IUR IRIS RfC
2.4E-03 (ug/m3)-1 IRIS RfC (1998) 2E-05 mg/m3
1,1'-Biphenyl
92-52-4
No inhalation-based toxicity factors are available
None
Bis(2-chloroethoxy) methane
111-91-1
No inhalation-based toxicity factors are available
None
Bis(2-chloroethyl) ether
111-44-4
No inhalation-based toxicity factors are available17
None
Bis(2-ethylhexyl) phthalate
117-81-7
No inhalation-based toxicity factors are available17
None
Bromodichloromethane
75-27-4
No inhalation-based toxicity factors are available17
None
No inhalation-based
Bromoform
75-25-2
toxicity factors are available17
None
Bromomethane
74-83-9
IRIS RfC
IRIS RfC (1992) 5E-03 mg/m3
2-Butanone
78-93-3
IRIS RfC3
IRIS RfC (2003) 5E+00 mg/m3
Butylbenzylphthalate
85-68-7
No inhalation-based toxicity factors are available
None
Cadmium
7440-43-9
IRIS IUR ATSDR RfC
IRIS IUR (1992) 1.8E-03 (ug/m3)-1 ATSDR RfC (2013) 1E-05 mg/m3
Caprolactam
105-60-2
CalEPA RfC
CalEPA RfC (2013) 2.2E-03 mg/m3
Carbon disulfide
75-15-0
IRIS RfC
IRIS RfC (1995) 7E-01 mg/m3
Carbon tetrachloride
56-23-5
IRIS IUR IRIS RfC
IRIS IUR (2010) 6E-06 (ug/m3)-1 IRIS RfC (2010) 1E-01 mg/m3 7
Chlordane (alpha plus gamma mixture)
57-74-9
IRIS RfC
IRIS RfC (1998) 7E-04 mg/m3
4-Chloroaniline
106-47-8
No inhalation-based toxicity factors are available
None
Chlorobenzene
108-90-7
PPRTV RfC
PPRTV RfC (2006) 5E-02 mg/m3
Chloroethane
75-00-3
IRIS RfC
IRIS RfC (1991)
ATSDR RfC No other inhalation-
ATSDR RfC (2013)
Chloroform
67-66-3
based toxicity factors are available17
1E+01 mg/m3 9.8E-02 mg/m3
Chloromethane
74-87-3
IRIS RfC4 No inhalation-based
IRIS RfC (2001) 9E-02 mg/m3
2-Chloronaphthalene
91-58-7
toxicity factors are available
None
2-Chlorophenol
95-57-8
No inhalation-based toxicity factors are available17
None
Chrysene
218-01-9
IRIS IUR (benzo(a) pyrene) adjusted for chrysene
IRIS IUR (2017) 6.0E-07 (ug/m3)-1 (adjusted for chrysene)
Cobalt
7440-48-4
PPRTV IUR PPRTV RfC
PPRTV IUR (2008) 9E-03(ug/m3)-1 PPRTV RfC (2008) 6E-06 mg/m3
Copper
7440-50-8
No inhalation-based toxicity factors are available5
None
Cyanide
57-12-5
IRIS RfC
IRIS RfC (2010) 8E-04 mg/m3
Cyclohexane
110-82-7
IRIS RfC
IRIS RfC (2003) 6E+00 mg/m3
4,4'-DDD
72-54-8
No inhalation-based toxicity factors are available17
None
4,4'-DDE
72-55-9
No inhalation-based toxicity factors are available17
None
4,4'-DDT
50-29-3
No inhalation-based toxicity factors are available17
None
Dibenz(a,h)anthracene
53-70-3
IRIS IUR (benzo(a) pyrene) adjusted for dibenzo(a,h) anthracene
IRIS IUR (2017) 6.0E-04(ug/m3)-1 (adjusted for dibenzo(a,h) anthracene)
Dibromochloromethane
124-48-1
No inhalation-based toxicity factors are available17
None PPRTV IUR (2006)
1,2-Dibromo-3-chloropropane
96-12-8
PPRTV IUR IRIS RfC
6E-03 (ug/m3)-1 IRIS RfC (1991) 2E-04 mg/m3
1,2-Dibromoethane
106-93-4
IRIS IUR IRIS RfC
IRIS IUR (2004) 6E-04 (ug/m3)-1 IRIS RfC (2004) 9E-03 mg/m3
1,2-Dichlorobenzene
95-50-1
HEAST RfC
HEAST RfC (1997) 2E-01 mg/m3
1,3-Dichlorobenzene
541-73-1
No inhalation-based toxicity factors are available
None
1,4-Dichlorobenzene
106-46-7
IRIS RfC No other inhalationbased toxicity factors are available17
IRIS RfC (1994) 8E-01 mg/m3
3,3'-Dichlorobenzidine
91-94-1
No inhalation-based toxicity factors are available
None
Dichlorodifluoromethane
75-71-8
No inhalation-based toxicity factors are available6
None
1,1-Dichloroethane
75-34-3
No inhalation-based toxicity factors are available7
None
1,2-Dichloroethane
107-06-2
PPRTV RfC No other inhalationbased toxicity factors are available17
PPRTV RfC (2010) 7E-03 mg/m3
1,1-Dichloroethene
75-35-4
A soil inhalation remediation standard can be developed using an IRIS RfC with a Group C carcinogen factor
IRIS RfC (2002/2005) 2E-01 mg/m3 RfC Group C carcinogen factor 10
cis-1,2-Dichloroethene
156-59-2
No inhalation-based toxicity factors are available
None
trans-1,2-Dichloroethene
156-60-5
No inhalation-based toxicity factors are available8
None
2,4-Dichlorophenol
120-83-2
No inhalation-based toxicity factors are available17
None
1,2-Dichloropropane
78-87-5
PPRTV IUR IRIS RfC
PPRTV IUR (2016) 3.7E-06 (ug/m3)-1 IRIS RfC (1991) 4E-03 mg/m3
1,3-Dichloropropene (cis and trans)
542-75-6
IRIS IUR IRIS RfC
IRIS IUR (2000) 4E-06 (ug/m3)-1 IRIS RfC (2000) 2E-02 mg/m3
Dieldrin
60-57-1
No inhalation-based toxicity factors are available
None
Diethylphthalate
84-66-2
No inhalation-based toxicity factors are available17
None
2,4-Dimethylphenol
105-67-9
No inhalation-based toxicity factors are available17
None
Di-n-butylphthalate
84-74-2
No inhalation-based toxicity factors are available17
None
2,4-Dinitrophenol
51-28-5
No inhalation-based toxicity factors are available17
None
2,4-Dinitrotoluene /2,6-Dinitrotoluene (mixture)
25321-14 6
No inhalation-based toxicity factors are available17
None
Di-n-octylphthalate
117-84-0
No inhalation-based toxicity factors are available9
None
1,4-Dioxane
123-91-1
IRIS IUR IRIS RfC
IRIS IUR (2013) 5.0E-06 (ug/m3)-1 IRIS RfC (2013) 3E-02 mg/m3
Endosulfan I and Endosulfan II (alpha and beta)
115-29-7
No inhalation-based toxicity factors are available17
None
Endrin
72-20-8
No inhalation-based toxicity factors are available17
None CalEPA IUR (2007)
Ethylbenzene
100-41-4
CalEPA IUR IRIS RfC
2.5E-06 (ug/m3)-1 IRIS RfC (1991) 1E+00 mg/m3
Extractable Petroleum Hydrocarbons (EPH) (Category 1)
various
No inhalation-based toxicity factors are available
None
Extractable Petroleum Hydrocarbons (EPH) (category 2)
various
No inhalation-based toxicity factors are available
None
Fluoranthene
206-44-0
No inhalation-based toxicity factors are available18
None
Fluorene
86-73-7
No inhalation-based toxicity factors are available18
None
alpha-HCH (alpha-BHC)
319-84-6
No inhalation-based toxicity factors are available17
None
beta-HCH (beta-BHC)
319-85-7
No inhalation-based toxicity factors are available17
None
Heptachlor
76-44-8
No inhalation-based toxicity factors are available17
None
Heptachlor epoxide
1024-57-3
No inhalation-based toxicity factors are available17
None
Hexachlorobenzene
118-74-1
No inhalation-based toxicity factors are available17
None
Hexachloro-1,3-butadiene
87-68-3
No inhalation-based toxicity factors are available17
None
Hexachlorocyclopentadiene
77-47-4
IRIS RfC
IRIS RfC (2001) 2E-04 mg/m3
Hexachloroethane
67-72-1
IRIS RfC
IRIS RfC (2011) 3E-02 mg/m3
n-Hexane
110-54-3
IRIS RfC
IRIS RfC (2005) 7E-01 mg/m3
2-Hexanone
591-78-6
IRIS RfC
IRIS RfC (2009) 3E-02 mg/m3
Indeno(1,2,3,-cd) pyrene
193-39-5
IRIS IUR (benzo(a) pyrene) adjusted for indeno(1,2,3,-cd) pyrene.
IRIS IUR (2017) 6.0E-05 (ug/m3)-1 (adjusted for indeno(1,2,3,-cd) pyrene)
Isophorone
78-59-1
CalEPA RfC
CalEPA RfC (2001) 2E-00 mg/m3
Isopropylbenzene
98-82-8
IRIS RfC
IRIS RfC (1997) 4E-01 mg/m3
Lead
7439-92-1
No inhalation-based toxicity factors are available17
None
Lindane (gamma-HCH) (gamma-BHC)
58-89-9
No inhalation-based toxicity factors are available17
None
Manganese
7439-96-5
IRIS RfC
IRIS RfC (1993) 5E-05 mg/m3
Mercury
7439-97-6
IRIS RfC
IRIS RfC (1995) 3E-04 mg/m3
Methoxychlor
72-43-5
No inhalation-based toxicity factors are available17
None
Methyl acetate
79-20-9
No inhalation-based toxicity factors are available
None
IRIS IUR (2011)
Methylene chloride
75-09-2
IRIS IUR IRIS RfC
1E-08 (ug/m3)-1 IRIS RfC (2011) 6E-01 mg/m3
2-Methylnaphthalene
91-57-6
No inhalation-based toxicity factors are available18
None
4-Methyl-2-pentanone
108-10-1
IRIS RfC
IRIS RfC (2003) 3E+00 mg/m3
2-Methylphenol
95-48-7
No inhalation-based toxicity factors are available17
None
4-Methylphenol
106-44-5
No inhalation-based toxicity factors are available17
None
Methyl tert-butyl ether (MTBE)
1634-04-4
CalEPA IUR IRIS RfC with a Group C carcinogen factor
CalEPA IUR (1999) 2.6E-07 (ug/m3)-1 IRIS RfC (1993) 3E+00 mg/m3 Group C carcinogen factor 10
Naphthalene
91-20-3
CalEPA IUR IRIS RfC with a Group C carcinogen factor
CalEPA IUR (2011) 3.4E-05 (ug/m3)-1 IRIS RfC (1998) 3E-03 mg/m3 Group C carcinogen factor 10
Nickel
7440-02-0
IRIS IUR CalEPA RfC
IRIS IUR (1987/2006) 2.4E-04 (ug/m3)-1 CalEPA RfC (2012) 1.4E-05 mg/m3
4-Nitroaniline
100-01-6
PPRTV RfC
PPRTV RfC (2009) 6E-03 mg/m3
IRIS IUR (2009)
Nitrobenzene
98-95-3
IRIS IUR IRIS RfC
4E-05 (ug/m3)-1 IRIS RfC (2009)
9E-03 mg/m3
No inhalation-based
N-Nitroso-di-n- propylamine
621-64-7
toxicity factors are available17
None
No inhalation-based
N-Nitrosodiphenylamine
86-30-6
toxicity factors are available17
None
No inhalation-based
2,2'-Oxybis(1-choloropropane)
108-60-1
toxicity factors are available
None
No inhalation-based
Pentachlorophenol
87-86-5
toxicity factors are
None
available17
Phenol
108-95-2
CalEPA RfC
CalEPA RfC (2000) 2E-01 mg/m3
No inhalation-based
Polychlorinated biphenyls (PCBs)
1336-36-3
toxicity factors are
None
available17 No inhalation-based
Pyrene
129-00-0
toxicity factors are
None
available18 No inhalation-based
Selenium
7782-49-2
toxicity factors are
None
available No inhalation-based
Silver
7440-22-4
toxicity factors are
None
available17
Styrene
100-42-5
IRIS RfC10
IRIS RfC (1992) 1E+00 mg/m3
No inhalation-based
Tertiary butyl alcohol (TBA)
75-65-0
toxicity factors are
None
available17 No inhalation-based
1,2,4,5-Tetrachlorobenzene
95-94-3
toxicity factors are
None
available No inhalation-based
2,3,7,8-Tetrachlorodibenzo-p-dioxin
1746-01-6
toxicity factors are
None
available No inhalation-based
1,1,2,2-Tetrachloroethane
79-34-5
toxicity factors are
None
available17
Tetrachloroethene (PCE)
127-18-4
IRIS IUR IRIS RfC
IRIS IUR (2012) 2.6E-07 (ug/m3)-1 IRIS RfC (2012) 4E-02 mg/m3
No inhalation-based
2,3,4,6-Tetrachlorophenol
58-90-2
toxicity factors are
None
available
IRIS RfC (2005)
Toluene
108-88-3
IRIS RfC
5E+00 mg/m3
No inhalation-based
Toxaphene
8001-35-2
toxicity factors are
None
available17
1,2,4-Trichlorobenzene
120-82-1
PPRTV RfC
PPRTV RfC (2009) 2E-03 mg/m3
IRIS RfC (2007)
1,1,1-Trichloroethane
71-55-6
IRIS RfC11
5E+00 mg/m3
1,1,2-Trichloroethane
79-00-5
No inhalation-based toxicity factors are available12
None
IRIS IUR (2011) 4.1E-
Trichloroethene (TCE)
79-01-6
IRIS IUR IRIS RfC13
06 (ug/m3)-1 IRIS RfC (2011) 2E-03 mg/m3
Trichlorofluoromethane
75-69-4
No inhalation-based toxicity factors are available14
None
2,4,5-Trichlorophenol
95-95-4
No inhalation-based toxicity factors are available17
None
2,4,6-Trichlorophenol
88-06-2
No inhalation-based toxicity factors are available17
None
1,1,2-Trichloro-1,2,2-trifluoroethane
76-13-1
PPRTV RfC
PPRTV RfC (2016) 5E+00 mg/m3
1,2,4-Trimethylbenzene
95-63-6
IRIS RfC
IRIS RfC (2016) 6E-02 mg/m3
Vanadium
7440-62-2
ATSDR RfC
1E-04 mg/m3
IRIS IUR (2000) 4.4E-
Vinyl Chloride
75-01-4
IRIS IUR IRIS RfC15
06 (ug/m3)-1 IRIS RfC (2000) 1E-01 mg/m3
Xylenes
1330-20-7
IRIS RfC
IRIS RfC (2003) 1.E-01 mg/m3
Zinc
7440-66-6
No inhalation-based toxicity factors are available16
None
1 An ATSDR RfC exists for acetone using the results of the Stewart 1975 study. The USEPA IRIS notes that this study should only be used in the development of a short-term exposure RfC and not a long-term (chronic) exposure RfC.
2 A HEAST RfC exists for acetophenone, but a subsequent PPRTV review (2010) questions the use of the HEAST RfC.
3 A NJDWQI RfC exists for 2-butanone, but the IRIS RfC has been determined by the Department to be more appropriate. The existing NJDWQI RfC is based on a route-to-route conversion of a NJDWQI RfD. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with USEPA policy concerning route-to-route conversion of toxicity factors.
4 A HEAST IUR exists for chloromethane, but a subsequent PPRTV review (2012) states that the use of the HEAST IUR is "Inadequate for an assessment of carcinogenic potential."
5 A CalEPA RfC that once existed for copper has been retracted by CalEPA.
6 A HEAST RfC and a PPRTV RfC exist for dichlorodifluoromethane. Both RfCs are derived using the same study (Prendergast 1967). The PPRTV is listed as an appendix value. The PPRTV RfC is listed as an appendix value because the Prendergast study was determined by the USEPA to have flaws. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop soil remediation standards. As the HEAST RfC developed using the Prendergast study, the Department decided not to use this RfC in the development of a soil remediation standard.
7 A HEAST RfC exists for 1,1-dichloroethane, but a subsequent PPRTV review (2006) indicated that data were inadequate to derive a chronic exposure RfC for 1,1-dichloroethane. A CalEPA IUR also exists for 1,1-dichloroethane but is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors.
8A PPRTV RfC exists for trans-1,2-dichloroethene but a subsequent IRIS assessment (2010) stated "the available inhalation data from the Freund study are insufficient to support reference value derivation and RfC."
9 A 1985 USEPA IUR that once existed for di-n-octylphthalate has been retracted by the USEPA.
10 A HEAST 1991 IUR exists for styrene but USEPA NCEA does not recommend its use.
11 Although an NJDWQI RfC exists for 1,1,1-trichloroethane, the Department determined that the IRIS RfC is a scientifically better toxicity value to develop a non-cancer-based soil inhalation remediation standard.
12 Although a PPRTV RfC for 1,1,2-trichloroethane exists, it is listed as an appendix value. The PPRTV appendix value is based on a study that was determined by USEPA to have flaws. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop soil remediation standards. An IRIS IUR also exists for 1,1,2-trichloroethane but is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors.
13 The IRIS RfC for trichloroethene is based on a route-to-route conversion of an ingestion study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.
14 A HEAST RfC exists for trichlorofluoromethane, but a subsequent PPRTV review (2009) indicated that data used to derive the RfC were inadequate.
15 The IRIS RfC for vinyl chloride is based on a route-to-route conversion of an ingestion study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.
16 A CalEPA RfC that once existed for zinc has been retracted by CalEPA.
*17There is an inhalation toxicity factor available for this contaminant, but it is based on a route-to-
route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted with physiologically-based pharmacokinetic modeling, for the development of soil remediation standards based on route-to-route conversion of toxicity factors.
18The 2008 inhalation toxicity factor was based on an equivalency factor from Nisbet and LaGoy (1992). Nisbet and LaGoy did not conduct any original research and relied on studies using dermal application and subcutaneous injection, with one study using intrapulmonary administration (not inhalation). The Nisbet and LaGoy study develops TEFs for PAHs compared to BP. The Department did not use this study because it was not derived from an inhalation study.
19The former IRIS RfC was withdrawn.
Table 3--Indoor Air Toxicity Factors
Contaminant
CAS No.
VI Recommendation
VI Toxicity Factor (s)
Acenaphthene
83-32-9
Not applicable No inhalation-based
Not applicable
Acetone
67-64-1
toxicity factors are available1
None
Acetophenone
98-86-2
Not applicable
Not applicable
Aldrin
309-00-2
Not applicable
Not applicable
Aluminum
7429-90-5
Not applicable
Not applicable
Anthracene
120-12-7
Not applicable
Not applicable
Antimony
7440-36-0
Not applicable
Not applicable
Arsenic
7440-38-2
Not applicable
Not applicable
Atrazine
1912-24-9
Not applicable
Not applicable
Barium
7440-39-3
Not applicable
Not applicable
Benzaldehyde
100-52-7
Not applicable
Not applicable
Benzene
71-43-2
IRIS IUR
IRIS IUR (2000)
IRIS RfC
7.8E-06 (ug/m3)-1
IRIS RfC (2003) 3E-02 mg/m3
Benzo(a)anthracene
56-55-3
Not applicable
Not applicable
Benzo(a)pyrene
50-32-8
Not applicable
Not applicable
Benzo(b)fluoranthene
205-99-2
Not applicable
Not applicable
Benzo(k)fluoranthene
207-08-9
Not applicable
Not applicable
Beryllium
7440-41-7
Not applicable
Not applicable
1,1'-Biphenyl
92-52-4
Not applicable
Not applicable
Bis(2-chloroethoxy) methane
111-91-1
Not applicable
Not applicable
Bis(2-chloroethyl) ether
111-44-4
Not applicable
Not applicable
Bis(2-ethylhexyl) phthalate
117-81-7
Not applicable
Not applicable
Bromodichloromethane
75-27-4
No inhalation-based toxicity factors are available13
None
No inhalation-based
Bromoform
75-25-2
toxicity factors are available13
None
Bromomethane
74-83-9
IRIS RfC
IRIS RfC (1992) 5E-03 mg/m3
2-Butanone
78-93-3
VI standard can be developed using IRIS RfC2
IRIS RfC (2003)
5E+00 mg/m3
Butylbenzylphthalate
85-68-7
Not applicable
Not applicable
Cadmium
7440-43-9
Not applicable
Not applicable
Caprolactam
105-60-2
Not applicable
Not applicable
Carbon disulfide
75-15-0
IRIS RfC
IRIS RfC (1995) 7E-01 mg/m3
Carbon tetrachloride
56-23-5
IRIS IUR
IRIS IUR (2010)
IRIS RfC
6E-06 (ug/m3)-1 IRIS RfC (2010) 1E-01 mg/m3
Chlordane
57-74-9
Not applicable
Not applicable
(alpha plus gamma mixture) 4-Chloroaniline
106-47-8
Not applicable
Not applicable
Chlorobenzene
108-90-7
PPRTV RfC
PPRTV RfC (2006)5E-02 mg/m3
Chloroethane
75-00-3
IRIS RfC
IRIS RfC (1991) 1E+01 mg/m3
Chloroform
67-66-3
ATSDR RfC
ATSDR RfC (2013)
No other inhalationbased toxicity factors are available13
9.8E-02 mg/m3
Chloromethane
74-87-3
IRIS RfC3
IRIS RfC (2001) 9E-02 mg/m3
2-Chloronaphthalene
91-58-7
Not applicable
Not applicable
2-Chlorophenol
95-57-8
Not applicable
Not applicable
Chrysene
218-01-9
Not applicable
Not applicable
Cobalt
7440-48-4
Not applicable
Not applicable
Copper
7440-50-8
Not applicable
Not applicable
Cyanide
57-12-5
Not applicable
Not applicable
Cyclohexane
110-82-7
IRIS RfC
IRIS RfC (2003) 6E+00 mg/m3
4,4'-DDD
72-54-8
Not applicable
Not applicable
4,4'-DDE
72-55-9
Not applicable
Not applicable
4,4'-DDT
50-29-3
Not applicable
Not applicable
Dibenz(a,h)anthracene
53-70-3
Not applicableNo inhalation-based
Not applicable
Dibromochloromethane
124-48-1
toxicity factors are available13
None
1,2-Dibromo-3-chloropropane
96-12-8
Not applicable
Not applicable
1,2-Dibromoethane
106-93-4
IRIS IUR
IRIS IUR (2004)
IRIS RfC
6E-04 (ug/m3)-1 IRIS RfC (2004) 9E-03 mg/m3
1,2-Dichlorobenzene
95-50-1
HEAST RfC
HEAST RfC (1997)2E-01 mg/m3
No inhalation-based
1,3-Dichlorobenzene
541-73-1
toxicity factors are available
None
1,4-Dichlorobenzene
106-46-7
IRIS RfC
IRIS RfC (1996)
No other inhalationbased toxicity factors are available13
8E-01 mg/m3
3,3'-Dichlorobenzidine
91-94-1
Not applicableNo inhalation-based
Not applicable
Dichlorodifluoromethane
75-71-8
toxicity factors are available4
None
No inhalation-based
1,1-Dichloroethane
75-34-3
toxicity factors are available5
None
1,2-Dichloroethane
107-06-2
PPRTV RfC
PPRTV RfC (2010)
No other inhalationbased toxicity factors are available13
7E-03 mg/m3
1,1-Dichloroethene
75-35-4
IRIS RfC with a Group C carcinogen factor
IRIS RfC (2002/2005)
2E-01 mg/m3
Group C carcinogen factor 10
No inhalation-based
cis-1,2-Dichloroethene
156-59-2
toxicity factors are available
None
No inhalation-based
trans-1,2-Dichloroethene
156-60-5
toxicity factors are available6
None
2,4-Dichlorophenol
120-83-2 78-87-5
PPRTV IUR
PPRTV IUR (2016)
IRIS RfC
3.7E-06 (ug/m3)-1
IRIS RfC (1991) 4E-03 mg/m3
1,3-Dichloropropene
5422-75-6
IRIS IUR
IRIS IUR (2000)
(cis and trans)
IRIS RfC
4E-06 (ug/m3)-1 IRIS RfC (2000) 2E-02 mg/m3
Dieldrin
60-57-1
Not applicable
Not applicable
Diethylphthalate
84-66-2
Not applicable
Not applicable
2,4-Dimethylphenol
105-67-9
Not applicable
Not applicable
Di-n-butylphthalate
84-74-2
Not applicable
Not applicable
2,4-Dinitrophenol
51-28-5
Not applicable
Not applicable
2,4-Dinitrotoluene /2,6-Dinitrotoluene(mixture)
25321-146
Not applicable
Not applicable
Di-n-octyl phthalate
117-84-0
Not applicable
Not applicable
1,4-Dioxane
123-91-1
IRIS IUR
IRIS IUR (2013)
IRIS RfC
5.0E-06 (ug/m3)-1
IRIS RfC (2013) 3E-02 mg/m3
Endosulfan I and Endosulfan II (alpha and beta)
115-29-7
Not applicable
Not applicable
Endrin
72-20-8
Not applicable
Not applicable
Ethylbenzene
100-41-4
CalEPA IUR
CalEPA IUR (2007)
IRIS RfC
2.5E-06 (ug/m3)-1
IRIS RfC (1991) 1E+00 mg/m3
Extractable Petroleum Hydrocarbons (EPH) (Category 1)
various
Not applicable
Not applicable
Extractable Petroleum Hydrocarbons (EPH) (Category 2)
various
Not applicable
Not applicable
Fluoranthene
206-44-0
Not applicable
Not applicable
Fluorene
86-73-7
Not applicable
Not applicable
alpha-HCH (alpha-BHC)
319-84-6
Not applicable
Not applicable
beta-HCH (beta-BHC)
319-85-7
Not applicable
Not applicable
Heptachlor
76-44-8
Not applicable
Not applicable
Heptachlor epoxide
1024-57-3
Not applicable
Not applicable
Hexachlorobenzene
118-74-1
Not applicable
Not applicable
Hexachloro-1,3-butadiene
87-68-3
No inhalation-based toxicity factors are available13
None
Hexachlorocyclopentadiene
77-47-4
Not applicable
Not applicable
Hexachloroethane
67-72-1
Not applicable
Not applicable
n-Hexane
110-54-3
IRIS RfC
IRIS RfC (2005)
7E-01 mg/m3
2-Hexanone
591-78-6
Not applicable
Not applicable
Indeno(1,2,3,-cd) pyrene
193-39-5
Not applicable
Not applicable
Isophorone
78-59-1
Not applicable
Not applicable
Isopropylbenzene
98-82-8
Not applicable
Not applicable
Lead
7439-92-1
Not applicable
Not applicable
Lindane (gamma-HCH) (gamma-BHC)
58-89-9
Not applicable
Not applicable
Manganese
7439-96-5
Not applicable
Not applicable
Mercury
7439-97-6
IRIS RfC
IRIS RfC (1995) 3E-04 mg/m3
Methoxychlor
72-43-5
Not applicableNo inhalation-based
Not applicable
Methyl acetate
79-20-9
toxicity factors are available
None
Methylene chloride
75-09-2
IRIS IUR
IRIS IUR (2011)
IRIS RfC
1E-08 (ug/m3)-1
IRIS RfC (2011)6E-01 mg/m3
2-Methylnaphthalene
91-57-6
Not applicable
Not applicable
4-Methyl-2-pentanone
108-10-1
IRIS RfC
IRIS RfC (2003)
3E +00 mg/m3
2-Methylphenol
95-48-7
Not applicable
Not applicable
4-Methylphenol
106-44-5
Not applicable
Not applicable
Methyl tert-butyl ether (MTBE)
1634-04-4
CalEPA IUR
CalEPA IUR (1999)
IRIS RfC
2.6E-07 (ug/m3)-1
IRIS RfC (1993)
3E +00 mg/m3
Naphthalene
91-20-3
CalEPA IUR
CalEPA IUR (2004)
IRIS RfC with a Group C
3.4E-05 (ug/m3)-
carcinogen factor
1IRIS RfC (1998) 3E-03 mg/m3 Group C carcinogen
Nickel
7440-02-0
Not applicable
Not applicable
4-Nitroaniline
100-01-6
Not applicable
Not applicable
Nitrobenzene
98-95-3
Not applicable
Not applicable
N-Nitroso-di-n propylamine
621-64-7
Not applicable
Not applicable
N-Nitrosodiphenylamine
86-30-6
Not applicable
Not applicable
2,2'-Oxybis(1-choloropropane)
108-60-1
Not applicable
Not applicable
Pentachlorophenol
87-86-5
Not applicable
Not applicable
Phenol
108-95-2
Not applicable
Not applicable
Polychlorinated biphenyls (PCBs)
1336-36-3
Not applicable
Not applicable
Pyrene
129-00-0
Not applicable
Not applicable
Selenium
7782-49-2
Not applicable
Not applicable
Silver
7440-22-4
Not applicable
Not applicable
Styrene
100-42-5
VI standard can be developed using IRIS RfC7
IRIS RfC (1993)
1E +00 mg/m3
No inhalation-based
Tertiary butyl alcohol (TBA)
75-65-0
toxicity factors are available13
None
1,2,4,5-Tetrachlorobenzene
95-94-3
Not applicable
Not applicable
2,3,7,8-Tetrachlorodibenzo-p-dioxin
1746-01-6
Not applicableNo inhalation-based
Not applicable
1,1,2,2-Tetrachloroethane
79-34-5
toxicity factors are available13
None
Tetrachloroethene (PCE)
127-18-4
IRIS IUR
IRIS IUR (2012)
IRIS RfC
2.6E-07 (ug/m3)-1
IRIS RfC (2012) 4E-02 mg/m3
2,3,4,6-Tetrachlorophenol
58-90-2
Not applicable
Not applicable
Toluene
108-88-3
IRIS RfC
IRIS RfC (2005)
5E +00 mg/m3
Toxaphene
8001-35-2
Not applicable
Not applicable
1,2,4-Trichlorobenzene
120-82-1
PPRTV RfC
PPRTV RfC (2009)2E-03 mg/m3
1,1,1-Trichloroethane
71-55-6
IRIS RfC8
IRIS RfC (2007)
5E +00 mg/m3
No inhalation-based
1,1,2-Trichloroethane
79-00-5
toxicity factors are available9
None
Trichloroethene (TCE)
79-01-6
IRIS IUR
IRIS IUR (2011)
IRIS RfC130>
4.1E-06 (ug/m3)-1
IRIS RfC (2011)
2E-03 mg/m3
No inhalation-based
Trichlorofluoromethane
75-69-4
toxicity factors are available131>
None
2,4,5-Trichlorophenol
95-95-4
Not applicable
Not applicable
2,4,6-Trichlorophenol
88-06-2
Not applicable
Not applicable
1,1,2-Trichloro-1,2,2-trifluoroethane
76-13-1
PPRTV RfC
PPRTV RfC (2016)5E+00 mg/m3
1,2,4-Trimethylbenzene
95-63-6
IRIS RfC
IRIS RfC (2016) 6E-02 mg/m3
Vanadium
7440-62-2
Not applicable
Not applicable
Vinyl Chloride
75-01-4
IRIS IUR.
IRIS IUR (2000)
IRIS RfC132>
4.4E-06 (ug/m3)-1
IRIS RfC (2000)
1E-01 mg/m3
Xylenes
1330-20-7
IRIS RfC
IRIS RfC (2003)1.E-01 mg/m3
Zinc
7440-66-6
Not applicable
Not applicable
1 An ATSDR RfC exists for acetone using the results of the Stewart 1975 study. The USEPA IRIS notes that this study should only be used in the development of a short-term exposure RfC and not a long-term (chronic) exposure RfC.
2 A NJDWQI RfC exists for 2-butanone, but the IRIS RfC has been determined by the Department to be more appropriate. The existing NJDWQI RfC is based on a route-to-route conversion of a NJDWQI RfD. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of indoor air remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route-to-route conversion of toxicity factors.
3 A HEAST IUR exists for chloromethane, but a subsequent PPRTV review (2012) states that the use of the HEAST IUR is "Inadequate for an assessment of carcinogenic potential."
4 A HEAST RfC and a PPRTV RfC exist for dichlorodifluoromethane. Both RfCs are derived using the same study (Prendergast 1967). The PPRTV is listed as an appendix value. The PPRTV RfC is listed as an appendix value because the Prendergast study was determined by the USEPA to have flaws. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop remediation standards. As the HEAST RfC was developed using the Prendergast study data, the Department decided not to use this RfC in the development of a remediation standard.
5 A HEAST RfC exists for 1,1-dichloroethane, but a subsequent PPRTV review (2006) indicated that data were inadequate to derive a chronic exposure RfC for 1,1-dichloroethane. A CalEPA IUR also exists for 1,1-dichloroethane but is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of indoor air remediation standards based on route-to-route conversion of toxicity factors.
6A PPRTV RfC exists for trans-1,2-dichloroethene but a subsequent IRIS assessment (2010) stated "the available inhalation data from the Freund study are insufficient to support reference value derivation and RfC." 7 A HEAST 1991 IUR exists for styrene but the USEPA NCEA does not recommend its use.
8 Although an NJDWQI RfC exists for 1,1,1-trichloroethane, the Department determined that the IRIS RfC is a scientifically better toxicity value to develop a non-cancer-based soil inhalation remediation standard.
9 Although a PPRTV RfC for 1,1,2-trichloroethane exists, it is listed as an appendix value. The PPRTV appendix value is based on a study that was determined by the USEPA to have flaws. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop remediation standards. An IRIS IUR also exists for 1,1,2-trichloroethane but is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of indoor air remediation standards based on route-to-route conversion of toxicity factors.
10 The IRIS RfC for trichloroethene is based on a route-to-route conversion of an ingestion study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.
11 A HEAST RfC exists for trichlorofluoromethane, but a subsequent PPRTV review (2009) indicated that data used to derive the RfC were inadequate.
12The IRIS RfC for vinyl chloride is based on a route-to-route conversion of an ingestion study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.
*13There is an inhalation toxicity factor available for this contaminant, but it is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted with physiologically-based pharmacokinetic modeling, for the development of indoor air remediation standards based on route-to-route conversion of toxicity factors.
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NJDEP (New Jersey Department of Environmental Protection). 1997. Interim Specific Criterion for Tertiary
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