reglab/statecodes huggingface dataset:
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 3 - Bureau of Acute Care Systems › Subpart 5 - Mississippi Hospital Sustainability Program › Chapter 1 - Mississippi Hospital Sustainability Grant Program Regulations › Subchapter 1 - General › Rule 15-3-5-1.1.4 - Required Application and Eligibility Documentation

Current through June 25, 2024
1.
					 The initial Program application window will open on June 1, 2023, and close at
					 11:59 pm CST on June 30, 2023.
2.
					 As per the ARPA Final Rule, the use of ARPA funds must be reasonably
					 proportional to the harm experienced. As such, applicants must submit revenue
					 and operating expense data from the fiscal years 2017, 2018, and 2019 as
					 compared to revenue and operating expenses for fiscal year 2022. Using the data
					 from FYs 2017-2019, a pre-pandemic baseline will be determined. This will be
					 compared to FY 2022 data to calculate the negative impact resulting from or
					 exacerbated by the pandemic. FY 2021 data can be considered but only for
					 periods beyond March 3, 2021, as required by ARPA guidelines. Data considered
					 for FY 2021 must be compared to the same time period from the pre-pandemic
					 fiscal years (e.g., if the non-Federal entity operates on a calendar year
					 basis, they may provide documentation showing data from April thru December
					 2021, but must show data for April thru December for FYs 2017-2019 in order to
					 perform an accurate comparison). This data must demonstrate a clear negative
					 impact resulting from or exacerbated by the pandemic.
3. Applicants must submit audited financial
					 statements for FYs 2017-2019, 2021 (if applicable), and 2022 to support the
					 revenue and operating expenses used in calculating the award. If audited or
					 reviewed financial statements are not available, internally prepared financials
					 may be provided but there may be additional procedures to be performed to
					 ensure the validity of the data. This will be evaluated on a case-by-case
					 basis.
4. Applicants will not be
					 reimbursed for increased operating expenses that occurred before March 3,
					 2021.
5. Applicants will not be
					 reimbursed for increased operating expenses previously reimbursed by any other
					 State or Federal funding and will be required to certify that no other funding
					 has been received in relation to the costs covered under this program. If
					 additional funding has been received, it will be factored into the award
					 calculation, as appropriate.
6.
					 None of the funds issued under this program shall be used to pay employee
					 premium payments.
House Bill
						271, 2023 Regular Legislative Session
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 3 - Bureau of Acute Care Systems › Subpart 5 - Mississippi Hospital Sustainability Program › Chapter 1 - Mississippi Hospital Sustainability Grant Program Regulations › Subchapter 1 - General › Rule 15-3-5-1.1.5 - Beneficiary Agreements

Current through June 25, 2024
Beneficiary agreements will be sent by the Program to the
						attention of the Administrator listed for the Eligible Beneficiary hospital
						utilizing the most current address on file at HFLC for the hospital. (Hospitals
						should maintain accurate contact information with HFLC)
1. Prior to release of any Program funds all
					 Eligible Beneficiaries will be required to certify, through a Beneficiary
					 Agreement, that it understands and agrees to certain required provisions,
					 including but not limited to, the following statements:
a. That the Eligible Beneficiary understands
					 and agrees to follow and comply with the guidelines, guidance, rules,
					 regulations and/or other criteria, as may be amended from time to time, by the
					 United States Department of the Treasury regarding the use of monies from the
					 American Rescue Plan established by the ARP Act;
b. That the Eligible Beneficiary understands
					 and agrees to follow and comply with all provisions of the Program, including
					 but not limited to, the Mississippi Hospital Sustainability Grant in Senate
					 Bill 2372, 2023 Regular Legislative Session, and the Department Mississippi
					 Hospital Sustainability Grant Program Rules and Regulations.
c. That, if the Eligible Beneficiary is found
					 to be fully or partially noncompliant with any Program requirements, the
					 Eligible Beneficiary agrees to return all or a portion any monies received from
					 the Program to the Department, and the Eligible Beneficiary understands that
					 it, or its legally responsible officials, may be subject to additional civil
					 and criminal penalties.
d. That the
					 Eligible Beneficiary certifies and acknowledges that by accepting reimbursement
					 under this Program for negative economic impact as a result of the COVID-19
					 pandemic, it may be subject to additional monitoring, oversight, and/or
					 auditing by the U.S. Department of Treasury's Office of the Inspector General,
					 the Mississippi Office of the State Auditor, the Mississippi State Department
					 of Health, or such other federal or state agencies with authority to conduct
					 such reviews;
e. That the Eligible
					 Beneficiary certifies it has not received and will not receive reimbursement
					 for the expense in question from any other source of funds, including insurance
					 proceeds.
f. The Beneficiary
					 Agreement must be signed under penalty of perjury certifying that all responses
					 and statements are true and correct and are not false, fraudulent, or
					 materially misleading.
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 3 - Bureau of Acute Care Systems › Subpart 5 - Mississippi Hospital Sustainability Program › Chapter 1 - Mississippi Hospital Sustainability Grant Program Regulations › Subchapter 1 - General › Rule 15-3-5-1.1.6 - Return of funds

Current through June 25, 2024
Any funds provided by the Department to a hospital as a
						beneficiary that are found to be fully or partially noncompliant with the
						requirements of the guidelines, guidance, rules, regulations and/or other
						criteria, as may be amended from time to time, by the United States Department
						of the Treasury regarding the use of monies from the American Rescue Plan Act
						(ARPA) of 2021, Public Laws
						117-2, Mississippi Hospital Sustainability Grant
						Program, or these rules and regulations shall be returned to the
						state.
Senate
						Bill 2372, 2023 Regular Legislative Session
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 3 - Bureau of Acute Care Systems › Subpart 5 - Mississippi Hospital Sustainability Program › Chapter 1 - Mississippi Hospital Sustainability Grant Program Regulations › Subchapter 1 - General › Rule 15-3-5-1.1.8 - Fraud Referrals

Current through June 25, 2024
In cases in which fraud is suspected or where false or
						materially misleading information or documentation has been provided by an
						Eligible Beneficiary, a written referral will be made to the Mississippi State
						Auditor's Office, the Office of the United States Attorney, or other
						appropriate federal or state agencies. The Department will cooperate fully in
						such investigations and provide all information and documentation which it has
						received or gathered on the Eligible Beneficiary.
Senate
						Bill 2372, 2023 Regular Legislative Session
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 3 - Bureau of Acute Care Systems › Subpart 5 - Mississippi Hospital Sustainability Program › Chapter 1 - Mississippi Hospital Sustainability Grant Program Regulations › Subchapter 1 - General › Rule 15-3-5-1.1.9 - Waiver

Current through June 25, 2024
The Mississippi Hospital Sustainability Grant Program
						Rules and Regulations may be amended by the Department at any time and are
						further subject to amendment pursuant to any change in the federal law
						providing for the grant funds and the regulations and guidance implemented
						related thereto. The Department, in its sole discretion, may temporarily waive
						any requirement of the Rules to the extent that the result of such waiver
						promotes the public purpose of the Mississippi Hospital Sustainability Grant
						Program created through S.B. 2372 of the 2023 Regular Legislative Session and
						is not prohibited by state or federal law.
Senate
						Bill 2372, 2023 Regular Legislative Session
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 3 - Bureau of Acute Care Systems › Subpart 5 - Mississippi Hospital Sustainability Program › Chapter 1 - Mississippi Hospital Sustainability Grant Program Regulations › Subchapter 1 - General › Rule 15-3-5-1.1.10 - Availability of Funds

Current through June 25, 2024
This Program is contingent upon the availability of funds
						as appropriated by the Legislature and provided by the Federal
						government.
Senate
						Bill 2372, 2023 Regular Legislative Session
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 1 - AUTHORITY › Rule 15-4-1-1.1.1 - Statutory Authority

Current through June 25, 2024
1. Sections
					  41-21-201 and  41-21-203 of the Mississippi Code of 1972, Annotated, authorizes
					 the State Department of Health to adopt rules and regulations to carry out the
					 Newborn Screening and Follow-up Program for hypothyroidism, phenylketonuria
					 (PKU), hemoglobinopathy, congenital adrenal hyperplasia (CAH), galactosemia,
					 and other such conditions listed on the Recommended Uniform Screening Panel
					 (RUSP) and as specified by the State Board of Health as stated herein below in
					 Rule 1.1.2.
2. Section  41-24-1 of
					 the Mississippi Code of 1972, Annotated, authorizes the State Department of
					 Health to adopt rules and regulations to establish a program of testing to
					 determine the presence of sickle cell trait or sickle cell anemia.
Miss. Code
						Ann. §
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 1 - AUTHORITY › Rule 15-4-1-1.1.2 - Legal Requirements

Current through June 25, 2024
1. Under the
					 statutory authority, conditions listed on the RUSP will be included in the
					 comprehensive newborn screening program within three (3) years after being
					 added to the RUSP and adopt any rules and regulations necessary to accomplish
					 the program.
a. If any RUSP-listed conditions
					 are not added to the comprehensive newborn screening program within three (3)
					 years, a report on the status and reasons for the delay will be submitted to
					 the House and Senate Public Health Committees once a year after the three-year
					 period.
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 2 - SPECIMEN COLLECTION › Rule 15-4-1-1.2.1 - Specimen Collection Requirements

Current through June 25, 2024
1.
					 The specimen must be dried blood spots for screening and whole blood for
					 confirmatory testing. Specimen should be collected according to the
					 instructions issued by the Newborn Screening Program and as specified in the
					 Child Health and Public Health Nursing Manuals.
2. Newborn screening should be performed
					 prior to hospital discharge. Any specimen collected prior to 24 hours of age
					 will require repeat specimen collection.
3. Newborn screening collection for Hgb is
					 accepted for testing under the assumption that the infant has not been
					 transfused. This statement is noted on Mississippi's newborn screening
					 collection card. The most recent transfusion date must be appropriately
					 documented on the collection card.
4. The performing laboratory must receive the
					 specimen within five working days of the date of collection. All specimens
					 requiring repeat testing will be monitored by the Newborn Screening Program as
					 follows:
a. Specimen repeated due to lack of
					 information will be the responsibility of the originating hospital.
b. All other repeat specimen will be followed
					 by the patient's local county health department unless there is a special
					 circumstance.
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 2 - SPECIMEN COLLECTION › Rule 15-4-1-1.2.2 - Fees

Current through June 25, 2024
A charge will be assessed for every infant screened to
						defray the cost of maintaining a central registry, lab testing and health
						department follow-up on positive and repeat tests, for all
						conditions.
Miss. Code Ann.
						§
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 3 - CCHD Reporting › Rule 15-4-1-1.3.1 - Reporting Requirements

Current through June 25, 2024
1. All infants
					 will receive a CCHD screening after 24 hours of age or before discharge.
a. All infants should be on room-air for at
					 least 24 hours and asymptomatic, including those in the NICU.
b. Neonatal intensive care unit (NICU)
					 infants who are stable and preparing for discharge.
c. Infants with a prenatal diagnosis of a
					 cardiac defect or infants who have already had a complete postnatal
					 echocardiogram performed should be excluded.
d. CCHD results must be entered on the
					 collection card for all screens done.
i. If
					 the CCHD screening results are not available and the bloodspot is ready to be
					 shipped. Ship the bloodspot specimen once it is dried.
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 3 - CCHD Reporting › Rule 15-4-1-1.3.2 - Fees

Current through June 25, 2024
1. A charge will be assessed for every infant
					 screened.
Miss. Code
						Ann. §
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 4 - FOLLOW-UP › Rule 15-4-1-1.4.1 - Documentation of Screening Outcomes

Current through June 25, 2024
1. The Newborn
					 Screening Program will be responsible for assuring that all infants have a CCHD
					 screening outcome documented.
a. Each
					 healthcare facility is responsible for providing additional information on all
					 infants that failed the CCHD Screening or did not have a "passed" result
					 documented on the Newborn Screening Collection Card.
i. Except in the case where the card is
					 marked as expired.
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 4 - FOLLOW-UP › Rule 15-4-1-1.4.2 - Follow-up for Positive Results, Questionable Results, and Repeat Screening

Current through June 25, 2024
1. The Newborn
					 Screening Program will be responsible for assuring that all infants with
					 positive, questionable, and repeat screening tests are appropriately followed.
					 Follow-up on infants who have a primary care provider will be coordinated with
					 the provider. The local health department will provide repeat follow-up on all
					 specimens that have been collected too early or improperly.
Miss. Code Ann.
						§
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 4 - FOLLOW-UP › Rule 15-4-1-1.4.3 - Repeat Screening Outside of the Health Department

Current through June 25, 2024
1. Special cases where the infant may have a
					 repeat completed outside of the health department are:
(1) Infant has not been discharged from the
					 birthing facility or
(2)
					 parent/guardian request to return to birthing facility due to parent
					 preference, location, or health department scheduling conflict.
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 4 - FOLLOW-UP › Rule 15-4-1-1.4.4 - Repeat Screening Due to Incomplete Collection Card

Current through June 25, 2024
1. If the newborn screening tests have to be
					 repeated due to lack of information on the collection card, the hospital will
					 be charged with finding the newborn and repeating the newborn screening
					 tests.
Miss. Code
						Ann. §
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 4 - FOLLOW-UP › Rule 15-4-1-1.4.5 - Disorders being Screened by Biochemical and Other Technologies

Current through June 25, 2024
1.
BIOTINIDASE DEFICIENCY:
Biotinidase Deficiency is caused by the
					 complete or partial lack of the enzyme biotinidase. This condition can lead to
					 seizures, developmental delay, eczema, and hearing loss.
2.
CONGENITAL ADRENAL
					 HYPERPLASIA:
Congenital Adrenal Hyperplasia (CAH) is a genetic endocrine
					 disorder caused primarily by a deficiency of enzymes needed for the adrenal
					 glands to make the hormones cortisol and aldosterone. It can result in
					 masculinization of female genitalia as well as adrenal crisis and early infant
					 death.
3.
CYSTIC
					 FIBROSIS
Cystic Fibrosis (CF) is an inherited condition that affects the
					 glands that produce mucus, tears, sweat, saliva, and digestive juices. It
					 causes severe lung damage and nutritional deficiencies. Respiratory failure is
					 the most dangerous consequence.
4.
CONGENITAL HYPOTHYROIDISM:
Hypothyroidism is a disorder in which
					 there is a decrease in the production of thyroid hormone, possibly resulting in
					 brain damage and mental retardation in the absence of prompt
					 treatment.
5.
GALACTOSEMIA:
Galactosemia is an inborn error of metabolism,
					 inherited as an autosomal-recessive trait, in which the hepatic enzyme
					 galactose-1-phosphate uridyl transferase is absent, preventing the conversion
					 of the milk sugar galactose to glucose. If untreated death can occur in the
					 first month of life.
6.
HEMOGLOBINOPATHIES:
Hemoglobinopathy, which includes sickle cell
					 diseases, thalassemia, and other variants are blood disorders resulting from
					 change in the structure of hemoglobin. Sickle Cell Disease, the most common
					 hemoglobinopathy in Mississippi, is an inherited disease found primarily in
					 African-Americans and people of Mediterranean descent. Although there is no
					 cure for sickle cell disease, early detection is important for effective
					 treatment and prevention of complications. Infection due to Streptococcus
					 pneumonia is a significant cause of death during the first few years of life
					 for patients with sickle cell disease.
Miss. Code Ann.
						§
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 4 - FOLLOW-UP › Rule 15-4-1-1.4.6 - Disorders Screened by Tandem Mass Spectrometry

Current through June 25, 2024
A tandem mass spectrometer is an analytical instrument
						consisting of two mass spectrometers in series connected by a reaction chamber
						or collision cell. It can identify a compound by its mass and determine how
						much of the compound is present. Through tandem mass spectrometry analysis,
						many genetic disorders can be detected from one blood specimen.
1.
MEDIUM CHAIN ACYL-COA DEHYDROGENASE
					 DEFICIENCY:
Medium Chain Acyl- CoA Dehydrogenase Deficiency (MCAD) is a
					 hereditary condition that is caused by a lack of an enzyme required to convert
					 fat to energy. For individuals with this condition, prolonged fasting can lead
					 to hypoglycemia, vomiting, lethargy, seizures, coma, apnea, cardiac arrest, or
					 sudden unexplained death.
2.
PHENYLKETONURIA:
Phenylketonuria (PKU) is a genetic disorder
					 inherited as an autosomal-recessive trait caused by the absence of an enzyme
					 that is necessary for metabolism of the essential amino acid phenylalanine. If
					 untreated, neurologic deterioration, seizures, and severe mental retardation
					 will occur.
3.
OTHER
					 DISORDERS:
Other less prevalent conditions are detectable by tandem mass
					 spectrometry. They are grouped into amino acid disorders, organic acid
					 disorders, and fatty acid disorders (See Attachment A). Many of these
					 conditions can be life threatening if appropriate and timely interventions are
					 not initiated.
Miss. Code Ann.
						§
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 4 - FOLLOW-UP › Rule 15-4-1-1.4.7 - RECORD RETENTION

Current through June 25, 2024
Records of standardization, quality control, and patient
						values must be kept for at least two years. It is advisable for laboratories to
						retain these records until the statute of limitations regarding medical
						malpractice actions expires as stipulated by Mississippi state law.
Miss. Code Ann.
						§
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 4 - FOLLOW-UP › Rule 15-4-1-1.4.8 - SPECIMEN RETENTION

Current through June 25, 2024
Specimen must be retained for at least 365 days. Under no
						circumstances will the retained specimen be used for research or purposes other
						than confirmation of previous test results.
Miss. Code Ann.
						§
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 5 - LABORATORY REQUIREMENTS › Rule 15-4-1-1.5.1 - Compliance with Standards

Current through June 25, 2024
1. Any
					 laboratory which offers this testing must meet the standards outlined in this
					 section and, if requested, provide the agency with a written statement that
					 they will comply with these standards. All specimens must be tested in an
					 approved laboratory located in the United States.
2. The results of hemoglobinopathies,
					 galactosemia, and congenital adrenal hyperplasia screening are not always clear
					 cut and this type of screening requires extensive input from a recognized
					 reference laboratory. Screening by tandem mass spectrometry requires extensive
					 expertise and experience in this testing methodology.
3. A single control laboratory is required
					 for screening. The laboratory should be proficient in all required testing
					 methodologies.
Miss. Code
						Ann. §
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 5 - LABORATORY REQUIREMENTS › Rule 15-4-1-1.5.2 - Specimen Requirements

Current through June 25, 2024
1. Specimen
					 acceptable for analysis includes only dried blood spots for newborn screening,
					 and whole blood or serum for confirmatory testing.
Miss. Code
						Ann. §
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 5 - LABORATORY REQUIREMENTS › Rule 15-4-1-1.5.3 - Method for Specimen Analysis

Current through June 25, 2024
1.
Argininemia
: Method: fluorometric assay or by tandem mass
					 spectrometry analysis
2.
Biotinidase Deficiency
: Method: continuous flow enzyme
					 assay
3.
Congenital
					 Hypothyroidism
: Method: Enzyme Immunoassay (EIA)
4.
Cystic Fibrosis (CF)
:
					 Immunoreactive Trypsinogen (IRT) Method: Immunoassay
5.
Congenital Adrenal Hyperplasia
					 (CAH)
: Method: Enzyme Immunoassay (EIA)
6.
Galactosemia
: Method:
					 continuous flow chemistry analysis for Galactose-1-Phospahte Uridyltransferase
					 deficiency
7.
Hemoglobinopathies
: Method: isoelectric focusing
8.
Phenylketonuria (PKU)
:
					 Method: continuous flow chemistry analysis or tandem mass spectrometry
					 analysis
9.
Other
					 Disorders
: Method: tandem mass spectrometry analysis, or biochemical and
					 other established technologies.
Miss. Code
						Ann. §
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 5 - LABORATORY REQUIREMENTS › Rule 15-4-1-1.5.4 - Quality Control

Current through June 25, 2024
1. The
					 laboratory must be successfully participating in an acceptable proficiency
					 testing program that will monitor the performance of all testing methodologies.
					 Acceptable testing programs include the following:
a. College of American Pathologists
					 (CAP)
b. American Association of
					 Clinical Chemists (AACC)
c. Centers
					 for Disease Control (CDC)
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 5 - LABORATORY REQUIREMENTS › Rule 15-4-1-1.5.5 - Disorders being Screened by Biochemical and Other Technologies

Current through June 25, 2024
1.
Biotinidase Deficiency:
Biotinidase Deficiency is caused by the complete or partial lack of the enzyme
					 biotinidase. This condition can lead to seizures, developmental delay, eczema,
					 and hearing loss.
2.
Congenital Adrenal Hyperplasia:
Congenital Adrenal Hyperplasia
					 (CAH) is a genetic endocrine disorder caused primarily by a deficiency of
					 enzymes needed for the adrenal glands to make the hormones cortisol and
					 aldosterone. It can result in masculinization of female genitalia as well as
					 adrenal crisis and early infant death.
3.
Cystic Fibrosis:
Cystic
					 Fibrosis (CF) is an inherited condition that affects the glands that produce
					 mucus, tears, sweat, saliva, and digestive juices. It causes severe lung damage
					 and nutritional deficiencies. Respiratory failure is the most dangerous
					 consequence.
4.
Congenital
					 Hypothyroidism:
Hypothyroidism is a disorder in which there is a
					 decrease in the production of thyroid hormone, possibly resulting in brain
					 damage and mental retardation in the absence of prompt treatment.
5.
Galactosemia:
Galactosemia is
					 an inborn error of metabolism, inherited as an autosomal-recessive trait, in
					 which the hepatic enzyme galactose-1-phosphate uridyl transferase is absent,
					 preventing the conversion of the milk sugar galactose to glucose. If untreated
					 death can occur in the first month of life.
6.
Hemoglobinopathies:
Hemoglobinopathy, which includes sickle cell diseases, thalassemia, and other
					 variants are blood disorders resulting from change in the structure of
					 hemoglobin. Sickle Cell Disease, the most common hemoglobinopathy in
					 Mississippi, is an inherited disease found primarily in African-Americans and
					 people of Mediterranean descent. Although there is no cure for sickle cell
					 disease, early detection is important for effective treatment and prevention of
					 complications. Infection due to Streptococcus pneumonia is a significant cause
					 of death during the first few years of life for patients with sickle cell
					 disease.
Miss. Code
						Ann. §
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 5 - LABORATORY REQUIREMENTS › Rule 15-4-1-1.5.6 - Disorders Screened by Tandem Mass Spectrometry

Current through June 25, 2024
1. A tandem mass spectrometer is an
					 analytical instrument consisting of two mass spectrometers in series connected
					 by a reaction chamber or collision cell. It can identify a compound by its mass
					 and determine how much of the compound is present. Through tandem mass
					 spectrometry analysis, many genetic disorders can be detected from one blood
					 specimen.
2.
Medium Chain
					 Acyl-CoA Dehydrogenase Deficiency:
Medium Chain Acyl-CoA Dehydrogenase
					 Deficiency (MCAD) is a hereditary condition that is caused by a lack of an
					 enzyme required to convert fat to energy. For individuals with this condition,
					 prolonged fasting can lead to hypoglycemia, vomiting, lethargy, seizures, coma,
					 apnea, cardiac arrest, or sudden unexplained death.
3.
Phenylketonuria:
Phenylketonuria (PKU) is a genetic disorder inherited as an autosomal-recessive
					 trait caused by the absence of an enzyme that is necessary for metabolism of
					 the essential amino acid phenylalanine. If untreated, neurologic deterioration,
					 seizures, and severe mental retardation will occur.
4.
Other Disorders:
Other less
					 prevalent conditions are detectable by tandem mass spectrometry. They are
					 grouped into amino acid disorders, organic acid disorders, and fatty acid
					 disorders (See Attachment A). Many of these conditions can be life threatening
					 if appropriate and timely interventions are not initiated.
Miss. Code
						Ann. §
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 5 - LABORATORY REQUIREMENTS › Rule 15-4-1-1.5.7 - Record Retention

Current through June 25, 2024
1. Records of
					 standardization, quality control, and patient values must be kept for at least
					 two years. It is advisable for laboratories to retain these records until the
					 statute of limitations regarding medical malpractice actions expires as
					 stipulated by Mississippi state law.
Miss. Code
						Ann. §
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 1 - NEWBORN SCREENING AND BIRTH DEFECTS REGISTRY › Subchapter 5 - LABORATORY REQUIREMENTS › Rule 15-4-1-1.5.8 - Specimen Retention

Current through June 25, 2024
1. Specimen must
					 be retained for at least 365 days. Under no circumstances will the retained
					 specimen be used for research or purposes other than confirmation of previous
					 test results.
Miss. Code
						Ann. §
												41-21-201
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 2 - BIRTH DEFECTS REGISTRY › Subchapter 1 - AUTHORITY › Rule 15-4-1-2.1.1 - Statutory Authority

Current through June 25, 2024
1. Section
					  41-21-205 of the Mississippi Code of 1972, Annotated, authorizes the State
					 Department of Health (the department) to adopt rules and regulations to govern
					 the operation of the Birth Defects Registry.
Miss. Code
						Ann. §
												41-21-205
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 2 - BIRTH DEFECTS REGISTRY › Subchapter 1 - AUTHORITY › Rule 15-4-1-2.1.2 - Legal Requirements

Current through June 25, 2024
Under the statutory authority, the Board of Health (the
						board) shall:
1. Establish in the
					 department a birth defects surveillance program to:
a. identify and investigate birth defects,
					 and
b. maintain a central registry
					 of cases of birth defects
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 2 - BIRTH DEFECTS REGISTRY › Subchapter 1 - AUTHORITY › Rule 15-4-1-2.1.3 - The Genetics Advisory Committee

Current through June 25, 2024
1.
					 The State Health Officer may appoint or delegate his authority for the purposes
					 of this section to an advisory committee, not to exceed (13) persons, to assist
					 in the design and implementation of this central registry with representation
					 from relevant groups including, but not limited to, hospitals, two (2)
					 pediatricians, board-certified clinical geneticists, personnel of the
					 department, personnel of other appropriate state agencies, and one (1) consumer
					 representative from a family that has experience with a newborn infant with an
					 abnormal screening test. If a central registry advisory committee is created by
					 the State Health Officer, the board shall consult and be advised by the
					 committee on the promulgation of rules, regulations and procedures for the
					 purposes of this section.
Miss. Code
						Ann. §
												41-21-205
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 4 - Office of Health Services › Subpart 1 - Bureau of Genetics › Chapter 3 - IDENTIFYING REPORTABLE CASES › Rule 15-4-1-3.1.1 - Definition of Birth Defect

Current through June 25, 2024
1.
Birth
				  Defect:
A birth defect is an abnormality of structure, function or
				  metabolism, whether genetically determined or a result of environmental
				  influences during embryonic or fetal life. A birth defect may present from the
				  time of conception through one year after birth, or later in life.
a. From birth to one year of age certain
				  principal birth defects shall be reported.
b. Other birth defects found later in life
				  may be reported at any time up to age twenty-one.
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 1 - Introduction › Rule 15-5-85-1.1.1

Current through June 25, 2024
This filing is a compilation of the procedures
						established for the orderly and timely registration of vital events in the
						state of Mississippi. These procedures are based on the Mississippi Code of
						1972, Annotated, and the rules adopted by the Mississippi Board of Health and
						filed with the Secretary of State in compliance with the Administrative
						Procedures Act.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7; Miss. Code Ann. §
												41-3-15; Miss. Code Ann. §
												41-3-17
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 1 - Introduction › Rule 15-5-85-1.1.2

Current through June 25, 2024
Mississippi Code sections are cited for easy reference by
						readers who wish to consult the related statutes. Cited sections are as of
						filing, any future changes, additions or deletions in the Code take precedence
						over the filed rules and regulations.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 2 - General Provisions › Rule 15-5-85-1.2.1 - Statutory Authority

Current through June 25, 2024
Statutory Authority: State statute mandates that a bureau
						of vital statistics be established by the Board of Health for the registration
						and preservation of vital events and statistics, and for the enforcement of
						such laws, rules, regulations, and orders.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 2 - General Provisions › Rule 15-5-85-1.2.2 - Rulemaking Authority

Current through June 25, 2024
The Board of Health has the authority to make reasonable
						rules and regulations to carry out its duties and the objectives of its
						creation.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7; Miss. Code Ann. §
												41-3-15; Miss. Code Ann. §
												41-3-17
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 4 - State Registrar › Rule 15-5-85-1.4.1

Current through June 25, 2024
In accordance with classification standards of education
						and experience a State Registrar of Vital Records shall be appointed by the
						Secretary of the Board of Health. The State Registrar shall be provided with
						such clerical and other assistance as needed to perform the duties of the
						position and shall be provided with suitable office space and fireproof vaults
						and filing cases for the permanent and safe preservation of all
						records.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7; Miss. Code Ann. §
												41-57-3; Miss. Code Ann. §
												41-57-43; Miss Code Ann. §
												41-57-48; Miss. Code Ann.
						§93-533
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 4 - State Registrar › Rule 15-5-85-1.4.2

Current through June 25, 2024
The State Registrar shall register and maintain reports
						of marriage prepared and filed by the clerk of the circuit court of each
						county, and reports of divorce prepared and filed by each clerk of the chancery
						court of each county. The clerk of the circuit court is the legal custodian of
						marriage licenses and certificates of marriage, and the clerk of the chancery
						court is the legal custodian of divorce decrees.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7; Miss. Code Ann. §
												41-57-43; Miss Code Ann. §
												41-57-48
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 4 - State Registrar › Rule 15-5-85-1.4.3 - Authority of the state registrar

Current through June 25, 2024
The State Registrar under the direction of the Board of
						Health shall execute and enforce the provisions of the laws and the rules and
						regulations and supervise registrars, to the end that all of the requirements
						shall be uniformly complied with. The State Registrar, personally or by
						authorized representative, shall have authority to investigate cases of
						irregularity or violation of regulation or law. When necessary, cases of
						violation of any of the provisions of the laws and regulations shall be
						reported, with a statement of facts and circumstances, to the prosecuting
						attorney of the proper county.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-3; Miss. Code Ann. §
												41-57-7
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 4 - State Registrar › Rule 15-5-85-1.4.4

Current through June 25, 2024
The State Registrar shall have the authority to
						cross-reference birth and death certificates on file for the same individual by
						notating on the face information necessary to show relation of the two
						certificates.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 4 - State Registrar › Rule 15-5-85-1.4.5

Current through June 25, 2024
Upon demand of the State Registrar in person, by mail, or
						through an authorized representative all physicians, coroners, midwives,
						administrators in institutions, informants, nurse midwives, or funeral
						directors, and all other persons having knowledge of the facts, shall furnish
						such information as they may possess regarding any live birth, death, fetal
						death, adoption, marriage, divorce, annulment or induced termination of
						pregnancy.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 4 - State Registrar › Rule 15-5-85-1.4.6

Current through June 25, 2024
The State Registrar shall have authority to participate
						with federal, state and local governmental and law enforcement agencies in
						investigations in which records or the information contained in a record is
						required.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7; Miss. Code Ann. §
												41-3-15(1)(c)(vi).
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 5 - Legal Standing of Certificates of Registrar › Rule 15-5-85-1.5.1

Current through June 25, 2024
Certificates of the State Registrar are the primary
						validation of any facts contained therein. Properly certified copies are to be
						taken and received as prima facie evidence of the facts stated therein in all
						Mississippi courts. Any questions concerning the validity of certified copies
						should be addressed to the State Registrar.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7; Miss. Code Ann §
												41-57-9; Miss. Code Ann. §
												41-57-47
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 6 - Penalties › Rule 15-5-85-1.6.1

Current through June 25, 2024
Violation of any rule, regulation or order of the Board
						of Health relative to recording, reporting or filing information, the willful
						neglect or refusal to provide information, or the willful furnishing of false
						information is a misdemeanor and conviction carries a fine of not more than
						five hundred dollars ($500.00) or imprisonment in the county jail not exceeding
						six (6) months, or both.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7; Miss. Code Ann §
												41-57-27; Miss. Code Ann. §
												41-57-59
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 7 - Venue › Rule 15-5-85-1.7.1

Current through June 25, 2024
Venue of any court action in which the Board of Health is
						a defendant is Hinds County, Mississippi. Actions may be brought in any justice
						court of the state which has jurisdiction of the subject matter but lacks venue
						without dismissal because of lack of proper venue. However, at the request of
						the defendant the case can be transferred to the proper
						venue.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7; Miss. Code Ann. §
												11-11-15; Miss. Code Ann. §
												11-11-17
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 8 - Registration Districts › Rule 15-5-85-1.8.1 - Registration districts

Current through June 25, 2024
The state is hereby defined and designated as the sole
						registration district to provide vital statistics
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7; Miss. Code Ann. §
												41-57-5
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 8 - Registration Districts › Rule 15-5-85-1.8.2 - Appointment of local registrars

Current through June 25, 2024
The State Registrar shall serve as the local registrar
						for all counties within the state. The State Registrar shall hire and authorize
						field representatives to assist in carrying out the rules and regulations
						promulgated under §
											41-57-7.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7
Mississippi Administrative Code › Title 15 - Mississippi Department of Health › Part 5 - Office of Health Informatics › Subpart 85 - Public Health Statistics › Chapter 1 - Rules Governing the Registration and Certification of Vital Events › Subchapter 8 - Registration Districts › Rule 15-5-85-1.8.3 - Authority of authorized field representatives

Current through June 25, 2024
Field representatives, authorized by the State Registrar,
						shall enforce, within the geographical areas assigned, the provisions of the
						laws and regulations under the supervision of the State Registrar. They shall
						make an immediate report to the State Registrar of any violations coming to
						their notice by observation or upon complaint of any person, or
						otherwise.
Miss. Code
						Ann. §
												41-57-1; Miss. Code Ann. §
												41-57-7