California Code of Regulations › Title 27 - Environmental Protection › Division 4 - Office of Environmental Health Hazard Assessment › Chapter 1 - Safe Drinking Water and Toxic Enforcement Act of 1986 › Article 9 - Miscellaneous › Section 27001 - Chemicals Known to the State to Cause Cancer or Reproductive Toxicity

Current through Register 2024 Notice Reg. No. 28, July 12, 2024
(a) The Safe
				  Drinking Water and Toxic Enforcement Act of 1986 requires that the Governor
				  revise and republish at least once per year the list of chemicals known to the
				  State to cause cancer or reproductive toxicity. The identification number
				  indicated in the following list is the Chemical Abstracts Service (CAS)
				  Registry Number. No CAS number is given when several substances are presented
				  as a single listing. The date refers to the initial appearance of the chemical
				  on the list.
(b) Chemicals known to
				  the state to cause cancer.
Chemical
CAS Number
Date
A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole)
26148-68-5
January 1, 1990
Acetaldehyde
75-07-0
April 1, 1988
Acetamide
60-35-5
January 1, 1990
Acetochlor
34256-82-1
January 1, 1989
2-Acetylaminofluorene
53-96-3
July 1, 1987
Acifluorfen sodium
62476-59-9
January 1, 1990
Acrylamide
79-06-1
January 1, 1990
Acrylonitrile
107-13-1
July 1, 1987
Actinomycin D
50-76-0
October 1, 1989
AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)]acrylamide
3688-53-7
July 1, 1987
Aflatoxins
--
January 1, 1988
Alachlor
15972-60-8
January 1, 1989
Alcoholic beverages
--
April 29, 2011
Alcoholic beverages, when associated with alcohol
							 abuse
--
July 1, 1988
Aldrin
309-00-2
July 1, 1988
Aloe vera, non-decolorized whole leaf extract
December 4, 2015
2-Aminoanthraquinone
117-79-3
October 1, 1989
p
-Aminoazobenzene
60-09-3
January 1, 1990
o
-Aminoazotoluene
97-56-3
July 1, 1987
4-Aminobiphenyl (4-amino-diphenyl)
92-67-1
February 27, 1987
2-Amino-4-chlorophenol
95-85-2
September 13, 2019
1-Amino-2,4-dibromoanthraquinone
81-49-2
August 26, 1997
3-Amino-9-ethylcarbazole hydrochloride
6109-97-3
July 1, 1989
2-Aminofluorene
153-78-6
January 29, 1999
1-Amino-2-methylanthraquinone
82-28-0
October 1, 1989
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole
712-68-5
July 1, 1987
4-Amino-2-nitrophenol
119-34-6
January 29, 1999
Amitrole
61-82-5
July 1, 1987
Amsacrine
51264-14-3
August 7, 2009
Analgesic mixtures containing phenacetin
--
February 27, 1987
Androstenedione
63-05-8
May 3, 2011
Aniline
62-53-3
January 1, 1990
Aniline hydrochloride
142-04-1
May 15, 1998
o
-Anisidine
90-04-0
July 1, 1987
o
-Anisidine hydrochloride
134-29-2
July 1, 1987
Anthracene
120-12-7
August 11, 2023
Anthraquinone
84-65-1
September 28, 2007
Antimony oxide (Antimony trioxide)
1309-64-4
October 1, 1990
Aramite
140-57-8
July 1, 1987
Areca nut
--
February 3, 2006
Aristolochic acids
--
July 9, 2004
Arsenic (inorganic arsenic compounds)
--
February 27, 1987
Asbestos
1332-21-4
February 27, 1987
Auramine
492-80-8
July 1, 1987
Azacitidine
320-67-2
January 1, 1992
Azaserine
115-02-6
July 1, 1987
Azathioprine
446-86-6
February 27, 1987
Azobenzene
103-33-3
January 1, 1990
Benthiavalicarb-isopropyl
177406-68-7
July 1, 2008
Benz[a]anthracene
56-55-3
July 1, 1987
Benzene
71-43-2
February 27, 1987
Benzidine [and its salts]
92-87-5
February 27, 1987
Benzidine-based dyes
--
October 1, 1992
Benzo[b]fluoranthene
205-99-2
July 1, 1987
Benzo[j]fluoranthene
205-82-3
July 1, 1987
Benzo[k]fluoranthene
207-08-9
July 1, 1987
Benzofuran
271-89-6
October 1, 1990
Benzophenone
119-61-9
June 22, 2012
Benzo[a]pyrene
50-32-8
July 1, 1987
Benzotrichloride
98-07-7
July 1, 1987
Benzyl chloride
100-44-7
January 1, 1990
Benzyl violet 4B
1694-09-3
July 1, 1987
Beryllium and beryllium compounds
--
October 1, 1987
Betel quid with tobacco
--
January 1, 1990
Betel quid without tobacco
--
February 3, 2006
2,2-Bis(bromomethyl)-1,3-propanediol
3296-90-0
May 1, 1996
Bis(2-chloroethyl)ether
111-44-4
April 1, 1988
N,N-Bis(2-chloroethyl)-2-naphthylamine
							 (Chlornapazine)
494-03-1
February 27, 1987
Bischloroethyl nitrosourea (BCNU) (Carmustine)
154-93-8
July 1, 1987
Bis(chloromethyl)ether
542-88-1
February 27, 1987
Bis(2-chloro-l-methylethyl)ether, technical grade
--
October 29, 1999
Bitumens, extracts of steam-refined and air
							 refined
--
January 1, 1990
Bracken fern
--
January 1, 1990
Bromate
15541-45-4
May 31, 2002
Bromochloroacetic acid
5589-96-8
April 6, 2010
1-Bromo-3-chloropropane
109-70-6
January 27, 2023
Bromodichloroacetic acid
71133-14-7
July 29, 2016
Bromodichloromethane
75-27-4
January 1, 1990
Bromoethane
74-96-4
December 22, 2000
Bromoform
75-25-2
April 1, 1991
1-Bromopropane (1-BP)
106-94-5
August 5, 2016
2-Bromopropane
45-26-3
August 11, 2023
1,3-Butadiene
106-99-0
April 1, 1988
1,4-Butanediol dimethanesulfonate (Busulfan)
55-98-1
February 27, 1987
Butylated hydroxyanisole
25013-16-5
January 1, 1990
1-Butyl glycidyl ether
2426-08-6
January 27, 2023
beta-Butyrolactone
3068-88-0
July 1, 1987
Cacodylic acid
75-60-5
May 1, 1996
Cadmium and cadmium compounds
--
October 1, 1987
Caffeic acid
331-39-5
October 1, 1994
Captafol
2425-06-1
October 1, 1988
Captan
133-06-2
January 1, 1990
Carbaryl
63-25-2
February 5, 2010
Carbazole
86-74-8
May 1, 1996
Carbon black (airborne, unbound particles of respirable
							 size)
1333-86-4
February 21, 2003
Carbon-black extracts
--
January 1, 1990
Carbon tetrachloride
56-23-5
October 1, 1987
N-Carboxymethyl-N-nitrosourea
60391-92-6
January 25, 2002
Catechol
120-80-9
July 15, 2003
Ceramic fibers (airborne particles of respirable
							 size)
--
July 1, 1990
Certain combined chemotherapy for lymphomas
--
February 27, 1987
Chloral
75-87-6
September 13, 2013
Chloral hydrate
302-17-0
September 13, 2013
Chlorambucil
305-03-3
February 27, 1987
Chloramphenicol sodium succinate
982-57-0
September 27, 2013
Chlordane
57-74-9
July 1, 1988
Chlordecone (Kepone)
143-50-0
January 1, 1988
Chlordimeform
6164-98-3
January 1, 1989
Chlorendic acid
115-28-6
July 1, 1989
Chlorinated paraffins (Average chain length, C12;
							 approximately 60 percent chlorine by weight)
108171-26-2
July 1, 1989
p
-Chloroaniline
106-47-8
October 1, 1994
p
-Chloroaniline hydrochloride
20265-96-7
May 15, 1998
Chloroethane (Ethyl chloride)
75-00-3
July 1, 1990
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)
							 (Lomustine)
13010-47-4
January 1, 1988
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea
							 (Methyl-CCNU)
13909-09-6
October 1, 1988
Chloroform
67-66-3
October 1, 1987
Chloromethyl methyl ether (technical grade)
107-30-2
February 27, 1987
3-Chloro-2-methylpropene
563-47-3
July 1, 1989
1-Chloro-4-nitrobenzene
100-00-5
October 29, 1999
2-Chloronitrobenzene
88-73-3
September 13, 2019
4-Chloro-
o
-phenylenediamine
95-83-0
January 1, 1988
Chloroprene
126-99-8
June 2, 2000
Chlorothalonil
1897-45-6
January 1, 1989
p
-Chloro-
o
-toluidine
95-69-2
January 1, 1990
p
-Chloro-
o
-toluidine, strong acid salts
							 of
--
May 15, 1998
5-Chloro-
o
-toluidine and its strong
							 acid salts
--
October 24, 1997
Chlorotrianisene
569-57-3
September 1, 1996
p
-chloro-?,?,?-trifluorotoluene
							 (
para
-Chlorobenzotrifluoride, PCBTF)
June 28, 2019
Chlorozotocin
54749-90-5
January 1, 1992
Chromium (hexavalent compounds)
--
February 27, 1987
Chrysene
218-01-9
January 1, 1990
C. I. Acid Red 114
6459-94-5
July 1, 1992
C.I. Basic Red 9 monohydrochloride
569-61-9
July 1, 1989
C.I. Direct Blue 15
2429-74-5
August 26, 1997
C.I. Direct Blue 218
28407-37-6
August 26, 1997
C.I. Disperse Yellow 3
2832-40-8
February 8, 2013
C.I. Solvent Yellow 14
842-07-9
May 15, 1998
Ciclosporin (Cyclosporin A; Cyclosporine)
59865-13-3
January 1, 1992
79217-60-0
Cidofovir
113852-37-2
January 29, 1999
Cinnamyl anthranilate
87-29-6
July 1, 1989
Cisplatin
15663-27-1
October 1, 1988
Citrus Red No. 2
6358-53-8
October 1, 1989
Clofibrate
637-07-0
September 1, 1996
Clomiphene citrate
50-41-9
May 24, 2013
CMNP (pyrazachlor)
6814-58-0
August 25, 2015
Coal-tar pitch
--
November 17, 2023
Cobalt metal powder
7440-48-4
July 1, 1992
Cobalt [II] oxide
1307-96-6
July 1, 1992
Cobalt sulfate
10124-43-3
May 20, 2005
Cobalt sulfate heptahydrate
10026-24-1
June 2, 2000
Coconut oil diethanolamine condensate (cocamide
							 diethanolamine)
--
June 22, 2012
Coke oven emissions
--
February 27, 1987
Conjugated estrogens
--
February 27, 1987
Creosotes
--
October 1, 1988
p
-Cresidine
120-71-8
January 1, 1988
Cumene
98-82-8
April 6, 2010
Cupferron
135-20-6
January 1, 1988
Cycasin
14901-08-7
January 1, 1988
Cyclopenta[
cd
]pyrene
27208-37-3
April 29, 2011
Cyclophosphamide (anhydrous)
50-18-0
February 27, 1987
Cyclophosphamide (hydrated)
6055-19-2
February 27, 1987
Cytembena
21739-91-3
May 15, 1998
D&C Orange No. 17
3468-63-1
July 1, 1990
D&C Red No. 8
2092-56-0
October 1, 1990
D&C Red No. 9
5160-02-1
July 1, 1990
D&C Red No. 19
81-88-9
July 1, 1990
Dacarbazine
4342-03-4
January 1, 1988
Daminozide
1596-84-5
January 1, 1990
Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone)
117-10-2
January 1, 1992
Daunomycin
20830-81-3
January 1, 1988
DDD (Dichlorodiphenyldichloroethane)
72-54-8
January 1, 1989
DDE (Dichlorodiphenyldichloroethylene)
72-55-9
January 1, 1989
DDT (Dichlorodiphenyltrichloroethane)
50-29-3
October 1, 1987
DDVP (Dichlorvos)
62-73-7
January 1, 1989
N,N'-Diacetylbenzidine
613-35-4
October 1, 1989
2,4-Diaminoanisole
615-05-4
October 1, 1990
2,4-Diaminoanisole sulfate
39156-41-7
January 1, 1988
4,4'-Diaminodiphenyl ether (4,4'-Oxydianiline)
101-80-4
January 1, 1988
2,4-Diaminotoluene
95-80-7
January 1, 1988
Diazoaminobenzene
136-35-6
May 20, 2005
Dibenz[a,h]acridine
226-36-8
January 1, 1988
Dibenz[a,j]acridine
224-42-0
January 1, 1988
Dibenzanthracenes
--
December 26, 2014
Dibenz[a,c]anthracene
215-58-7
December 26, 2014
Dibenz[a,h]anthracene
53-70-3
January 1, 1988
Dibenz[a,j]anthracene
224-41-9
December 26, 2014
7H-Dibenzo[c,g]carbazole
194-59-2
January 1, 1988
Dibenzo[a,e]pyrene
192-65-4
January 1, 1988
Dibenzo[a,h]pyrene
189-64-0
January 1, 1988
Dibenzo[a,i]pyrene
189-55-9
January 1, 1988
Dibenzo[a,l]pyrene
191-30-0
January 1, 1988
Dibromoacetic acid
631-64-1
June 17, 2008
Dibromoacetonitrile
3252-43-5
May 3, 2011
1,2-Dibromo-3-chloropropane (DBCP)
96-12-8
July 1, 1987
2,3-Dibromo-1-propanol
96-13-9
October 1, 1994
Dichloroacetic acid
79-43-6
May 1, 1996
p
-Dichlorobenzene
106-46-7
January 1, 1989
3,3'-Dichlorobenzidine
91-94-1
October 1, 1987
3,3'-Dichlorobenzidine dihydrochloride
612-83-9
May 15, 1998
1,4-Dichloro-2-butene
764-41-0
January 1, 1990
3,3'-Dichloro-4,4'-diaminodiphenyl ether
28434-86-8
January 1, 1988
1,1-Dichloroethane
75-34-3
January 1, 1990
Dichloromethane (Methylene chloride)
75-09-2
April 1, 1988
1,4-Dichloro-2-nitrobenzene
89-61-2
September 13, 2019
2,4-Dichloro-1-nitrobenzene
661-06-3
September 13, 2019
1,2-Dichloropropane
78-87-5
January 1, 1990
1,3-Dichloro-2-propanol (1,3-DCP)
96-23-1
October 8, 2010
1,3-Dichloropropene
542-75-6
January 1, 1989
Diclofop-methyl
51338-27-3
April 6, 2010
Dieldrin
60-57-1
July 1, 1988
Diepoxybutane
1464-53-5
January 1, 1988
Diesel engine exhaust
--
October 1, 1990
Diethanolamine
111-42-2
June 22, 2012
Di(2-ethylhexyl)phthalate (DEHP)
117-81-7
January 1, 1988
1,2-Diethylhydrazine
1615-80-1
January 1, 1988
Diethylstilbestrol (DES)
56-53-1
February 27, 1987
Diethyl sulfate
64-67-5
January 1, 1988
Diglycidyl resorcinol ether (DGRE)
101-90-6
July 1, 1989
Dihydrosafrole
94-58-6
January 1, 1988
Diisononyl phthalate (DINP)
--
December 20, 2013
Diisopropyl sulfate
2973-10-6
April 1, 1993
3,3'-Dimethoxybenzidine
							 (
o
-Dianisidine)
119-90-4
January 1, 1988
3,3'-Dimethoxybenzidine dihydrochloride
							 (
o
-Dianisidine dihydrochloride)
20325-40-0
October 1, 1990
3,3'-Dimethoxybenzidine-based dyes metabolized to
							 3,3'-dimethoxybenzidine
--
June 11, 2004
N,N-Dimethylacetamide
127-19-5
September 13, 2019
4-Dimethylaminoazobenzene
60-11-7
January 1, 1988
trans
-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)vinyl]-1,3,4-oxadiazole
55738-54-0
January 1, 1988
7,12-Dimethylbenz(a)anthracene
57-97-6
January 1, 1990
3,3'-Dimethylbenzidene (ortho-Tolidine)
119-93-7
January 1, 1988
3,3'-Dimethylbenzidine-based dyes metabolized to
							 3,3'-dimethylbenzidine
--
June 11, 2004
3,3'-Dimethylbenzidine dihydrochloride
612-82-8
April 1, 1992
Dimethylcarbamoyl chloride
79-44-7
January 1, 1988
N,N-Dimethylformamide
68-12-2
October 27, 2017
1,1-Dimethylhydrazine (UDMH)
57-14-7
October 1, 1989
1,2-Dimethylhydrazine
540-73-8
January 1, 1988
Dimethyl Hydrogen Phosphite
868-85-9
August 11, 2023
2,6-Dimethyl-N-nitrosomorpholine (DMNM)
1456-28-6
February 8, 2013
Dimethyl sulfate
77-78-1
January 1, 1988
N
,
N
-Dimethyl-
p
-toluidine
99-97-8
May 2, 2014
Dimethylvinylchloride
513-37-1
July 1, 1989
3,7-Dinitrofluoranthene
105735-71-5
August 26, 1997
3,9-Dinitrofluoranthene
22506-53-2
August 26, 1997
1,3-Dinitropyrene
75321-20-9
November 2, 2012
1,6-Dinitropyrene
42397-64-8
October 1, 1990
1,8-Dinitropyrene
42397-65-9
October 1, 1990
Dinitrotoluene mixture, 2,4-/2,6-
--
May 1, 1996
2,4-Dinitrotoluene
121-14-2
July 1, 1988
2,6-Dinitrotoluene
606-20-2
July 1, 1995
Di-
n
-propyl isocinchomeronate (MGK
							 Repellent 326)
136-45-8
May 1, 1996
1,4-Dioxane
123-91-1
January 1, 1988
Diphenylhydantoin (Phenytoin)
57-41-0
January 1, 1988
Diphenylhydantoin (Phenytoin), sodium salt
630-93-3
January 1, 1988
Direct Black 38 (technical grade)
1937-37-7
January 1, 1988
Direct Blue 6 (technical grade)
2602-46-2
January 1, 1988
Direct Brown 95 (technical grade)
16071-86-6
October 1, 1988
Disperse Blue 1
2475-45-8
October 1, 1990
Diuron
330-54-1
May 31, 2002
Doxorubicin hydrochloride (Adriamycin)
25316-40-9
July 1, 1987
Emissions from combustion of coal
--
August 7, 2013
Emissions from high-temperature unrefined rapeseed
							 oil
--
January 3, 2014
Epichlorohydrin
106-89-8
October 1, 1987
Epoxiconazole
135319-73-2
April 15, 2011
Erionite
12510-42-8/
October 1, 1988
66733-21-9
Estradiol 17B
50-28-2
January 1, 1988
Estragole
140-67-0
October 29, 1999
Estrogens, steroidal
--
August 19, 2005
Estrogen-progestogen (combined) used as menopausal
							 therapy
--
November 4, 2011
Estrone
53-16-7
January 1, 1988
Estropipate
7280-37-7
August 26, 1997
Ethinylestradiol
57-63-6
January 1, 1988
Ethoprop
13194-48-4
February 27, 2001
Ethyl acrylate
140-88-5
July 1, 1989
Ethylbenzene
100-41-4
June 11, 2004
Ethyl-4,4'-dichlorobenzilate
510-15-6
January 1, 1990
Ethylene dibromide
106-93-4
July 1, 1987
Ethylene dichloride (1,2-Dichloroethane)
107-06-2
October 1, 1987
Ethyleneimine (Aziridine)
151-56-4
January 1, 1988
Ethylene oxide
75-21-8
July 1, 1987
Ethylene thiourea
96-45-7
January 1, 1988
2-Ethylhexyl acrylate
103-11-7
December 17, 2021
Ethyl methanesulfonate
62-50-0
January 1, 1988
Etoposide
33419-42-0
November 4, 2011
Etoposide in combination with cisplatin and
							 bleomycin
--
November 4, 2011
Fenoxycarb
72490-01-8
June 2, 2000
Fluoro-edenite fibrous amphibole
--
November 17, 2023
Folpet
133-07-3
January 1, 1989
Formaldehyde (gas)
50-00-0
January 1, 1988
2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole
3570-75-0
January 1, 1988
Fumonisin B1
116355-83-0
November 14, 2003
Furan
110-00-9
October 1, 1993
Furazolidone
67-45-8
January 1, 1990
Furfuryl alcohol
98-00-0
September 30, 2016
Furmecyclox
60568-05-0
January 1, 1990
Fusarin C
79748-81-5
July 1, 1995
Gallium arsenide
1303-00-0
August 1, 2008
Ganciclovir
82410-32-0
August 26, 1997
Gasoline engine exhaust (condensates/extracts)
--
October 1, 1990
Gemfibrozil
25812-30-0
December 22, 2000
Gentian violet (Crystal violet)
548-62-9
November 23, 2018
Glass wool fibers (inhalable and biopersistent)
--
July 1, 1990
Glu-P-1
							 (2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole)
67730-11-4
January 1, 1990
Glu-P-2 (2-Aminodipyrido[1,2-a:3', 2'-d]imidazole)
67730-10-3
January 1, 1990
Glycidaldehyde
765-34-4
January 1, 1988
Glycidol
556-52-5
July 1, 1990
Glycidyl methacrylate
106-91-2
January 27, 2023
Glyphosate
1071-83-6
July 7, 2017
Goldenseal root powder
December 4, 2015
Griseofulvin
126-07-8
January 1, 1990
Gyromitrin (Acetaldehyde methylformylhydrazone)
16568-02-8
January 1, 1988
HC Blue 1
2784-94-3
July 1, 1989
Heptachlor
76-44-8
July 1, 1988
Heptachlor epoxide
1024-57-3
July 1, 1988
Herbal remedies containing plant species of the genus
Aristolochia
--
July 9, 2004
Hexachlorobenzene
118-74-1
October 1, 1987
Hexachlorobutadiene
87-68-3
May 3, 2011
Hexachlorocyclohexane (technical grade)
--
October 1, 1987
Hexachlorodibenzodioxin
34465-46-8
April 1, 1988
Hexachloroethane
67-72-1
July 1, 1990
2,4-Hexadienal (89% trans, trans isomer; 11% cis, trans
							 isomer)
--
March 4, 2005
Hexamethylphosphoramide
680-31-9
January 1, 1988
Hydrazine
302-01-2
January 1, 1988
Hydrazine sulfate
10034-93-2
January 1, 1988
Hydrazobenzene (1,2-Diphenylhydrazine)
122-66-7
January 1, 1988
1-Hydroxyanthraquinone
129-43-1
May 27, 2005
Imazalil
35554-44-0
May 20, 2011
Indeno [1,2,3-cd]pyrene
193-39-5
January 1, 1988
Indium phosphide
22398-80-7
February 27, 2001
Indium tin oxide
50926-11-9
March 19, 2021
IQ (2-Amino-3-methylimidazo[4,5-f] quinoline)
76180-96-6
April 1, 1990
Iprodione
36734-19-7
May 1, 1996
Iprovalicarb
140923-17-7
June 1, 2007
140923-25-7
Iron dextran complex
9004-66-4
January 1, 1988
Isobutyl nitrite
542-56-3
May 1, 1996
Isoprene
78-79-5
May 1, 1996
Isopyrazam
881685-58-1
July 24, 2012
Isoxaflutole
141112-29-0
December 22, 2000
Kresoxim-methyl
143390-89-0
February 3, 2012
Lactofen
77501-63-4
January 1, 1989
Lasiocarpine
303-34-4
April 1, 1988
Lead acetate
301-04-2
January 1, 1988
Lead and lead compounds
--
October 1, 1992
Lead phosphate
7446-27-7
April 1, 1988
Lead subacetate
1335-32-6
October 1, 1989
Leather dust
--
April 29, 2011
Leucomalachite green
129-73-7
April 21, 2023
Lindane and other hexachlorocyclohexane isomers
--
October 1, 1989
Lynestrenol
52-76-6
February 27, 2001
Malathion
121-75-5
May 20, 2016
Malonaldehyde, sodium salt
24382-04-5
May 3, 2011
Mancozeb
8018-01-7
January 1, 1990
Maneb
12427-38-2
January 1, 1990
Marijuana smoke
--
June 19, 2009
Me-A-alpha-C
							 (2-Amino-3-methyl-9H-pyrido[2,3-b]indole)
68006-83-7
January 1, 1990
Medroxyprogesterone acetate
71-58-9
January 1, 1990
Megestrol acetate
595-33-5
March 28, 2014
MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline)
77094-11-2
October 1, 1994
MeIQx
							 (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline)
77500-04-0
October 1, 1994
Melphalan
148-82-3
February 27, 1987
Mepanipyrim
110235-47-7
July 1, 2008
2-Mercaptobenzothiazole
149-30-4
October 27, 2017
Merphalan
531-76-0
April 1, 1988
Mestranol
72-33-3
April 1, 1988
Metam potassium
137-41-7
December 31, 2010
Metham sodium
137-42-8
November 6, 1998
5-Methoxypsoralen with ultraviolet A therapy
484-20-8
October 1, 1988
8-Methoxypsoralen with ultraviolet A therapy
298-81-7
February 27, 1987
Methyl acrylate
96-33-3
December 17, 2021
2-Methylaziridine (Propyleneimine)
75-55-8
January 1, 1988
Methylazoxymethanol
590-96-5
April 1, 1988
Methylazoxymethanol acetate
592-62-1
April 1, 1988
Methyl carbamate
598-55-0
May 15, 1998
3-Methylcholanthrene
56-49-5
January 1, 1990
5-Methylchrysene
3697-24-3
April 1, 1988
4,4'-Methylene bis(2-chloroaniline)
101-14-4
July 1, 1987
4,4'-Methylene bis(N,N-dimethyl)benzenamine
101-61-1
October 1, 1989
4,4'-Methylene bis(2-methylaniline)
838-88-0
April 1, 1988
4,4'-Methylenedianiline
101-77-9
January 1, 1988
4,4'-Methylenedianiline dihydrochloride
13552-44-8
January 1, 1988
Methyleugenol
93-15-2
November 16, 2001
Methylhydrazine and its salts
--
July 1, 1992
2-Methylimidazole
693-98-1
June 22, 2012
4-Methylimidazole
822-36-6
January 7, 2011
Methyl iodide
74-88-4
April 1, 1988
Methyl isobutyl ketone
108-10-1
November 4, 2011
Methylmercury compounds
--
May 1, 1996
Methyl methanesulfonate
66-27-3
April 1, 1988
2-Methyl-1-nitroanthraquinone (of uncertain
							 purity)
129-15-7
April 1, 1988
N-Methyl-N'-nitro-N-nitrosoguanidine
70-25-7
April 1, 1988
N-Methylolacrylamide
924-42-5
July 1, 1990
[ALPHA]-Methyl styrene (alpha-Methylstyrene)
98-83-9
November 2, 2012
Methylthiouracil
56-04-2
October 1, 1989
Metiram
9006-42-2
January 1, 1990
Metronidazole
443-48-1
January 1, 1988
Michler's ketone
90-94-8
January 1, 1988
Mirex
2385-85-5
January 1, 1988
Mitomycin C
50-07-7
April 1, 1988
Mitoxantrone hydrochloride
70476-82-3
January 23, 2015
Molybdenum trioxide
1313-27-5
March 19, 2021
MON 4660
							 (dichloroacetyl-1-oxa-4-azaspiro(4,5)-decane)
71526-07-3
March 22, 2011
MON 13900 (furilazole)
121776-33-8
March 22, 2011
3-Monochloropropane-1,2-diol (3-MCPD)
96-24-2
October 8, 2010
Monocrotaline
315-22-0
April 1, 1988
MOPP (vincristine-prednisone-nitrogen
							 mustard-procarbazine mixture)
113803-47-7
November 4, 2011
5-(Morpholinomethyl)-3-[(5-nitrofurfuryl-idene)-amino]-2-oxazolidinone
139-91-3
April 1, 1988
Mustard Gas
505-60-2
February 27, 1987
MX
							 (3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone)
77439-76-0
December 22, 2000
beta-Myrcene
123-35-3
March 27, 2015
Nafenopin
3771-19-5
April 1, 1988
Nalidixic acid
389-08-2
May 15, 1998
Naphthalene
91-20-3
April 19, 2002
1-Naphthylamine
134-32-7
October 1, 1989
2-Naphthylamine
91-59-8
February 27, 1987
Nickel (Metallic)
7440-02-0
October 1, 1989
Nickel acetate
373-02-4
October 1, 1989
Nickel carbonate
3333-67-3
October 1, 1989
Nickel carbonyl
13463-39-3
October 1, 1987
Nickel compounds
--
May 7, 2004
Nickel hydroxide
12054-48-7;
October 1, 1989
12125-56-3
Nickelocene
1271-28-9
October 1, 1989
Nickel oxide
1313-99-1
October 1, 1989
Nickel refinery dust from the pyrometallurgical
							 process
--
October 1, 1987
Nickel subsulfide
12035-72-2
October 1, 1987
Niridazole
61-57-4
April 1, 1988
Nitrapyrin
1929-82-4
October 5, 2005
Nitrilotriacetic acid
139-13-9
January 1, 1988
Nitrilotriacetic acid, trisodium salt monohydrate
18662-53-8
April 1, 1989
5-Nitroacenaphthene
602-87-9
April 1, 1988
o
-Nitroanisole
91-23-6
October 1, 1992
para-Nitroanisole
100-17-4
September 13, 2019
Nitrobenzene
98-95-3
August 26, 1997
4-Nitrobiphenyl
92-93-3
April 1, 1988
6-Nitrochrysene
7496-02-8
October 1, 1990
Nitrofen (technical grade)
1836-75-5
January 1, 1988
2-Nitrofluorene
607-57-8
October 1, 1990
Nitrofurazone
59-87-0
January 1, 1990
1-[(5-Nitrofurfurylidene)-amino]-2-imidazolidinone
555-84-0
April 1, 1988
N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide
531-82-8
April 1, 1988
Nitrogen mustard (Mechlorethamine)
51-75-2
January 1, 1988
Nitrogen mustard hydrochloride (Mechlorethamine
							 hydrochloride)
55-86-7
April 1, 1988
Nitrogen mustard N-oxide
126-85-2
April 1, 1988
Nitrogen mustard N-oxide hydrochloride
302-70-5
April 1, 1988
Nitromethane
75-52-5
May 1, 1997
2-Nitropropane
79-46-9
January 1, 1988
1-Nitropyrene
5522-43-0
October 1, 1990
4-Nitropyrene
57835-92-4
October 1, 1990
N-Nitrosodi-
n
-butylamine
924-16-3
October 1, 1987
N-Nitrosodiethanolamine
1116-54-7
January 1, 1988
N-Nitrosodiethylamine
55-18-5
October 1, 1987
N-Nitrosodimethylamine
62-75-9
October 1, 1987
p
-Nitrosodiphenylamine
156-10-5
January 1, 1988
N-Nitrosodiphenylamine
86-30-6
April 1, 1988
N-Nitrosodi-
n
-propylamine
621-64-7
January 1, 1988
N-Nitroso-N-ethylurea
759-73-9
October 1, 1987
N-Nitrosohexamethyleneimine
932-83-2
November 23, 2018
3-(N-Nitrosomethylamino)propionitrile
60153-49-3
April 1, 1990
4-(N-Nitrosomethylamino)-1-(3-pyridyl)1-butanone
64091-91-4
April 1, 1990
N-Nitrosomethyl-
n
-butylamine
7068-83-9
December 26, 2014
N-Nitrosomethyl-
n
-decylamine
75881-22-0
December 26, 2014
N-Nitrosomethyl-
n
-dodecylamine
55090-44-3
December 26, 2014
N-Nitrosomethylethylamine
10595-95-6
October 1, 1989
N-Nitrosomethyl-
n
-heptylamine
16338-99-1
December 26, 2014
N-Nitrosomethyl-
n
-hexylamine
28538-70-7
December 26, 2014
N-Nitrosomethyl-
n
-nonylamine
75881-19-5
December 26, 2014
N-Nitrosomethyl-
n
-octylamine
34423-54-6
December 26, 2014
N-Nitrosomethyl-
n
-pentylamine
13256-07-0
December 26, 2014
N-Nitrosomethyl-
n
-propylamine
924-46-9
December 26, 2014
N-Nitrosomethyl-
n
-tetradecylamine
75881-20-8
December 26, 2014
N-Nitrosomethyl-
n
-undecylamine
68107-26-6
December 26, 2014
N-Nitroso-N-methylurea
684-93-5
October 1, 1987
N-Nitroso-N-methylurethane
615-53-2
April 1, 1988
N-Nitrosomethylvinylamine
4549-40-0
January 1, 1988
N-Nitrosomorpholine
59-89-2
January 1, 1988
N-Nitrosonornicotine
16543-55-8
January 1, 1988
N-Nitrosopiperidine
100-75-4
January 1, 1988
N-Nitrosopyrrolidine
930-55-2
October 1, 1987
N-Nitrososarcosine
13256-22-9
January 1, 1988
o-Nitrotoluene
88-72-2
May 15, 1998
Norethisterone (Norethindrone)
68-22-4
October 1, 1989
Norethynodrel
68-23-5
February 27, 2001
Ochratoxin A
303-47-9
July 1, 1990
Oil Orange SS
2646-17-5
April 1, 1988
Oral contraceptives, combined
--
October 1, 1989
Oral contraceptives, sequential
--
October 1, 1989
Oryzalin
19044-88-3
September 12, 2008
Oxadiazon
19666-30-9
July 1, 1991
Oxazepam
604-75-1
October 1, 1994
Oxymetholone
434-07-1
January 1, 1988
Oxythioquinox (Chinomethionat)
2439-01-2
August 20, 1999
Palygorskite fibers (>5?m in length)
12174-11-7
December 28, 1999
Panfuran S
794-93-4
January 1, 1988
Parathion
56-38-2
May 20, 2016
Pentabromodiphenyl ether mixture [DE-71 (technical
							 grade)]
--
July 7, 2017
Pentachlorophenol
87-86-5
January 1, 1990
Pentachlorophenol and by-products of its synthesis
							 (complex mixture)
--
October 21, 2016
Pentosan polysulfate sodium
--
April 18, 2014
Perfluorooctane sulfonic acid (PFOS) and its salts and
							 transformation and degradation precursors
--
December 24, 2021
Perfluorooctanoic Acid (PFOA)
335-67-1
February 25, 2022
Phenacetin
62-44-2
October 1, 1989
Phenazopyridine
94-78-0
January 1, 1988
Phenazopyridine hydrochloride
136-40-3
January 1, 1988
Phenesterin
3546-10-9
July 1, 1989
Phenobarbital
50-06-6
January 1, 1990
Phenolphthalein
77-09-8
May 15, 1998
Phenoxybenzamine
59-96-1
April 1, 1988
Phenoxybenzamine hydrochloride
63-92-3
April 1, 1988
o
-Phenylenediamine and its salts
95-54-5
May 15, 1998
Phenyl glycidyl ether
122-60-1
October 1, 1990
Phenylhydrazine and its salts
--
July 1, 1992
o
-Phenylphenate, sodium
132-27-4
January 1, 1990
o
-Phenylphenol
90-43-7
August 4, 2000
PhiP(2-Amino-1-methyl-6-phenylimidazol[4,5-b]pyridine)
105650-23-5
October 1, 1994
Pioglitazone
111025-46-8
April 18, 2014
Pirimicarb
23103-98-2
July 1, 2008
Polybrominated biphenyls
--
January 1, 1988
Polychlorinated biphenyls
--
October 1, 1989
Polychlorinated biphenyls (containing 60 or more
							 percent chlorine by molecular weight)
--
January 1, 1988
Polychlorinated dibenzo-
p
-dioxins
--
October 1, 1992
Polychlorinated dibenzofurans
--
October 1, 1992
Polygeenan
53973-98-1
January 1, 1988
Ponceau MX
3761-53-3
April 1, 1988
Ponceau 3R
3564-09-8
April 1, 1988
Potassium bromate
7758-01-2
January 1, 1990
Primidone
125-33-7
August 20, 1999
Procarbazine
671-16-9
January 1, 1988
Procarbazine hydrochloride
366-70-1
January 1, 1988
Procymidone
32809-16-8
October 1, 1994
Progesterone
57-83-0
January 1, 1988
Pronamide
23950-58-5
May 1, 1996
Propachlor
1918-16-7
February 27, 2001
1,3-Propane sultone
1120-71-4
January 1, 1988
Propargite
2312-35-8
October 1, 1994
beta-Propiolactone
57-57-8
January 1, 1988
Propoxur
114-26-1
August 11, 2006
Propylene glycol mono-
t
-butyl
							 ether
57018-52-7
June 11, 2004
Propylene oxide
75-56-9
October 1, 1988
Propylthiouracil
51-52-5
January 1, 1988
Pulegone
89-82-7
April 18, 2014
Pymetrozine
123312-89-0
March 22, 2011
Pyridine
110-86-1
May 17, 2002
Quinoline and its strong acid salts
--
October 24, 1997
Radionuclides
--
July 1, 1989
Reserpine
50-55-5
October 1, 1989
Residual (heavy) fuel oils
--
October 1, 1990
Resmethrin
10453-86-8
July 1, 2008
Riddelliine
23246-96-0
December 3, 2004
Safrole
94-59-7
January 1, 1988
Salted fish, Chinese-style
--
April 29, 2011
Sedaxane
874967-67-6
July 1, 2016
Selenium sulfide
7446-34-6
October 1, 1989
Shale-oils
68308-34-9
April 1, 1990
Silica, crystalline (airborne particles of respirable
							 size)
--
October 1, 1988
Silicon carbide whiskers
--
November 17, 2023
Soots, tars, and mineral oils (untreated and mildly
							 treated oils and used engine oils)
--
February 27, 1987
Spirodiclofen
148477-71-8
October 8, 2010
Spironolactone
52-01-7
May 1, 1997
Stanozolol
10418-03-8
May 1, 1997
Sterigmatocystin
10048-13-2
April 1, 1988
Streptozotocin (streptozocin)
18883-66-4
January 1, 1988
Strong inorganic acid mists containing sulfuric
							 acid
--
March 14, 2003
Styrene
100-42-5
April 22, 2016
Styrene oxide
96-09-3
October 1, 1988
Sulfallate
95-06-7
January 1, 1988
Sulfasalazine (Salicylazosulfapyridine)
599-79-1
May 15, 1998
Talc containing asbestiform fibers
--
April 1, 1990
Tamoxifen and its salts
10540-29-1
September 1, 1996
Teriparatide
52232-67-4
August 14, 2015
Terrazole
2593-15-9
October 1, 1994
Testosterone and its esters
58-22-0
April 1, 1988
Tetrabromobisphenol A
79-94-7
October 27, 2017
3,3',4,4'-Tetrachloroazobenzene
14047-09-7
July 24, 2012
2,3,7,8-Tetrachlorodibenzo-
p
-dioxin
							 (TCDD)
1746-01-6
January 1, 1988
1,1,1,2-Tetrachloroethane
630-20-6
September 13, 2013
1,1,2,2-Tetrachloroethane
79-34-5
July 1, 1990
Tetrachloroethylene (Perchloroethylene)
127-18-4
April 1, 1988
p-?,?,?-Tetrachlorotoluene
5216-25-1
January 1, 1990
Tetrachlorvinphos
22248-79-9
May 20, 2016
Tetrafluoroethylene
116-14-3
May 1, 1997
Tetrahydrofuran
109-99-9
December 17, 2021
Tetranitromethane
509-14-8
July 1, 1990
Thioacetamide
62-55-5
January 1, 1988
4,4'-Thiodianiline
139-65-1
April 1, 1988
Thiodicarb
59669-26-0
August 20, 1999
Thiouracil
141-90-2
June 11, 2004
Thiourea
62-56-6
January 1, 1988
Thorium dioxide
1314-20-1
February 27, 1987
Titanium dioxide (airborne, unbound particles of
							 respirable size)
--
September 2, 2011
Tobacco, oral use of smokeless products
--
April 1, 1988
Tobacco smoke
--
April 1, 1988
Toluene diisocyanate
26471-62-5
October 1, 1989
o
-Toluidine
95-53-4
January 1, 1988
o
-Toluidine hydrochloride
636-21-5
January 1, 1988
Toxaphene (Polychorinated camphenes)
8001-35-2
January 1, 1988
Toxins derived from
Fusarium moniliforme
							 (Fusarium verticillioides)
--
August 7, 2009
Treosulfan
299-75-2
February 27, 1987
Triamterene
396-01-0
April 18, 2014
S,S,S-Tributyl phosphorotrithioate (Tribufos, DEF)
78-48-8
February 25, 2011
Trichlormethine (Trimustine hydrochloride)
817-09-4
January 1, 1992
Trichloroacetic acid
76-03-9
September 13, 2013
1,1,1-Trichloroethane
71-55-6
April 21, 2023
Trichloroethylene
79-01-6
April 1, 1988
2,4,6-Trichlorophenol
88-06-2
January 1, 1988
1,2,3-Trichloropropane
96-18-4
October 1, 1992
2,4,5-Trimethylaniline and its strong acid salts
--
October 24, 1997
Trimethylolpropane triacrylate, technical grade
--
December 17, 2021
Trimethyl phosphate
512-56-1
May 1, 1996
TRIM® VX
--
May 25, 2018
2,4,6-Trinitrotoluene (TNT)
118-96-7
December 19, 2008
Triphenyltin hydroxide
76-87-9
July 1, 1992
Tris(1-aziridinyl)phosphine sulfide (Thiotepa)
52-24-4
January 1, 1988
Tris(2-chloroethyl)phosphate
115-96-8
April 1, 1992
Tris(2,3-dibromopropyl)phosphate
126-72-7
January 1, 1988
Tris(1,3-dichloro-2-propyl) phosphate (TDCPP)
13674-87-8
October 28, 2011
Trp-P-1 (Tryptophan-P-1)
62450-06-0
April 1, 1988
Trp-P-2 (Tryptophan-P-2)
62450-07-1
April 1, 1988
Trypan blue (commercial grade)
72-57-1
October 1, 1989
Unleaded gasoline (wholly vaporized)
--
April 1, 1988
Uracil mustard
66-75-1
April 1, 1988
Urethane (Ethyl carbamate)
51-79-6
January 1, 1988
Vanadium pentoxide (orthorhombic crystalline form)
1314-62-1
February 11, 2005
Vinclozolin
50471-44-8
August 20, 1999
Vinyl bromide
593-60-2
October 1, 1988
Vinyl chloride
75-01-4
February 27, 1987
4-Vinylcyclohexene
100-40-3
May 1, 1996
4-Vinyl-1-cyclohexene diepoxide (Vinyl cyclohexene
							 dioxide)
106-87-6
July 1, 1990
Vinyl fluoride
75-02-5
May 1, 1997
Vinylidene chloride (1,1-Dichloroethylene)
75-35-4
December 29, 2017
Vinyl trichloride (1,1,2-Trichloroethane)
79-00-5
October 1, 1990
Wood dust
--
December 18, 2009
2,6-Xylidine (2,6-Dimethylaniline)
87-62-7
January 1, 1991
Zalcitabine
7481-89-2
August 7, 2009
Zidovudine (AZT)
30516-87-1
December 18, 2009
Zileuton
111406-87-2
December 22, 2000
(c) Chemicals known to the state to cause
				  reproductive toxicity.
Chemical
Type of Reproductive
							 Toxicity
CAS Number
Date
Abiraterone acetate
developmental, female, male
154229-18-2
April 8, 2016
Acetazolamide
developmental
59-66-5
August 20, 1999
Acetohydroxamic acid
developmental
546-88-3
April 1, 1990
Acrylamide
developmental, male
79-06-1
February 25, 2011
Actinomycin D
developmental
50-76-0
October 1, 1992
All-trans retinoic acid
developmental
302-79-4
January 1, 1989
Alprazolam
developmental
28981-97-7
July 1, 1990
Altretamine
developmental, male
645-05-6
August 20, 1999
Amantadine hydrochloride
developmental
665-66-7
February 27, 2001
Amikacin sulfate
developmental
39831-55-5
July 1, 1990
Aminoglutethimide
developmental
125-84-8
July 1, 1990
Aminoglycosides
developmental
--
October 1, 1992
Aminopterin
developmental, female
54-62-6
July 1, 1987
Amiodarone hydrochloride
developmental, female, male
19774-82-4
August 26, 1997
Amitraz
developmental
33089-61-1
March 30, 1999
Amoxapine
developmental
14028-44-5
May 15, 1998
Anabolic steroids
female, male
--
April 1, 1990
Angiotensin converting enzyme (ACE) inhibitors
developmental
--
October 1, 1992
Anisindione
developmental
117-37-3
October 1, 1992
Arsenic (inorganic oxides)
developmental
--
May 1, 1997
Aspirin (NOTE: It is especially important not to use
							 aspirin during the last three months of pregnancy, unless specifically directed
							 to do so by a physician because it may cause problems in the unborn child or
							 complications during delivery.)
developmental, female
50-78-2
July 1, 1990
Atenolol
developmental
29122-68-7
August 26, 1997
Atrazine
developmental, female
1912-24-9
July 15, 2016
Auranofin
developmental
34031-32-8
January 29, 1999
Avermectin B1 (Abamectin)
developmental
71751-41-2
December 3, 2010
Azathioprine
developmental
446-86-6
September 1, 1996
Barbiturates
developmental
--
October 1, 1992
Beclomethasone dipropionate
developmental
5534-09-8
May 15, 1998
Benomyl
developmental, male
17804-35-2
July 1, 1991
Benzene
developmental, male
71-43-2
December 26, 1997
Benzodiazepines
developmental
--
October 1, 1992
Benzphetamine hydrochloride
developmental
5411-22-3
April 1, 1990
Bevacizumab
developmental
216974-75-3
March 8, 2019
Bischloroethyl nitrosourea (BCNU) (Carmustine)
developmental
154-93-8
July 1, 1990
Bisphenol A (BPA)
female
80-05-7
May 11, 2015
Bisphenol A (BPA)
developmental
80-05-7
December 18, 2020
Bisphenol S (BPS)
female
80-09-1
December 29, 2023
Bromacil lithium salt
developmental
53404-19-6
May 18, 1999
male
January 17, 2003
1-Bromopropane (1-BP)
developmental, female, male
106-94-5
December 7, 2004
2-Bromopropane (2-BP)
female, male
75-26-3
May 31, 2005
Bromoxynil
developmental
1689-84-5
October 1, 1990
Bromoxynil octanoate
developmental
1689-99-2
May 18, 1999
Butabarbital sodium
developmental
143-81-7
October 1, 1992
1,3-Butadiene
developmental, female, male
106-99-0
April 16, 2004
1,4-Butanediol dimethanesulfonate (Busulfan)
developmental
55-98-1
January 1, 1989
Butyl benzyl phthalate (BBP)
developmental
85-68-7
December 2, 2005
Cadmium
developmental, male
--
May 1, 1997
Cannabis (marijuana) smoke
developmental
--
January 3, 2020
Carbamazepine
developmental
298-46-4
January 29, 1999
Carbaryl
developmental, female, male
63-25-2
August 7, 2009
Carbon disulfide
developmental, female, male
75-15-0
July 1, 1989
Carbon monoxide
developmental
630-08-0
July 1, 1989
Carboplatin
developmental
41575-94-4
July 1, 1990
Chenodiol
developmental
474-25-9
April 1, 1990
Chlorambucil
developmental
305-03-3
January 1, 1989
Chlorcyclizine hydrochloride
developmental
1620-21-9
July 1, 1987
Chlordecone (Kepone)
developmental
143-50-0
January 1, 1989
Chlordiazepoxide
developmental
58-25-3
January 1, 1992
Chlordiazepoxide hydrochloride
developmental
438-41-5
January 1, 1992
1-(2-Chloroethyl)-3-cyclohexyl-l-nitrosourea (CCNU)
							 (Lomustine)
developmental
13010-47-4
July 1, 1990
Chloroform
developmental
67-66-3
August 7, 2009
2-Chloropropionic acid
male
598-78-7
August 7, 2009
Chlorpyrifos
developmental
2921-88-2
December 15, 2017
Chromium (hexavalent compounds)
developmental, female, male
--
December 19, 2008
Cidofovir
developmental, female, male
113852-37-2
January 29, 1999
Cladribine
developmental
4291-63-8
September 1, 1996
Clarithromycin
developmental
81103-11-9
May 1, 1997
Clobetasol propionate
developmental, female
25122-46-7
May 15, 1998
Clomiphene citrate
developmental
50-41-9
April 1, 1990
Clorazepate dipotassium
developmental
57109-90-7
October 1, 1992
Cocaine
developmental, female
50-36-2
July 1, 1989
Codeine phosphate
developmental
52-28-8
May 15, 1998
Colchicine
developmental, male
64-86-8
October 1, 1992
Conjugated estrogens
developmental
--
April 1, 1990
Cyanazine
developmental
21725-46-2
April 1, 1990
Cycloate
developmental
1134-23-2
March 19, 1999
Cycloheximide
developmental
66-81-9
January 1, 1989
Cyclophosphamide (anhydrous)
developmental, female, male
50-18-0
January 1, 1989
Cyclophosphamide (hydrated)
developmental, female, male
6055-19-2
January 1, 1989
Cyhexatin
developmental
13121-70-5
January 1, 1989
Cytarabine
developmental
147-94-4
January 1, 1989
Dacarbazine
developmental
4342-03-4
January 29, 1999
Danazol
developmental
17230-88-5
April 1, 1990
Daunorubicin hydrochloride
developmental
23541-50-6
July 1, 1990
2,4-D butyric acid
male
94-82-6
June 18, 1999
o,p'-DDT
developmental, female, male
789-02-6
May 15, 1998
p,p'-DDT
developmental, female, male
50-29-3
May 15, 1998
Demeclocycline hydrochloride (internal use)
developmental
64-73-3
January 1, 1992
Des-ethyl atrazine (DEA)
developmental, female
6190-65-4
July 15, 2016
Des-isopropyl atrazine (DIA)
developmental, female
1007-28-9
July 15, 2016
2,4-Diamino-6-chloro-
s
-triazine
							 (DACT)
developmental, female
3397-62-4
July 15, 2016
Diazepam
developmental
439-14-5
January 1, 1992
Diazoxide
developmental
364-98-7
February 27, 2001
1,2-Dibromo-3-chloropropane (DBCP)
male
96-12-8
February 27, 1987
Dichloroacetic acid
developmental, male
79-43-6
August 7, 2009
1,1-Dichloro-2,2-bis(
p
-chlorophenyl)-ethylene
							 (DDE)
developmental, male
72-55-9
March 30, 2010
Dichlorophene
developmental
97-23-4
April 27, 1999
Dichlorphenamide
developmental
120-97-8
February 27, 2001
Diclofop methyl
developmental
51338-27-3
March 5, 1999
Dicumarol
developmental
66-76-2
October 1, 1992
Di(2-ethylhexyl)phthalate (DEHP)
developmental, male
117-81-7
October 24, 2003
Diethylstilbestrol (DES)
developmental
56-53-1
July 1, 1987
Diflunisal
developmental, female
22494-42-4
January 29, 1999
Dihydroergotamine mesylate
developmental
6190-39-2
May 1, 1997
Di-isodecyl phthalate (DIDP)
developmental
68515-49-1/
April 20, 2007
26761-40-0
Diltiazem hydrochloride
developmental
33286-22-5
February 27, 2001
N,N-Dimethylacetamide
developmental, male
127-19-5
May 21, 2010
Di-
n
-butyl phthalate (DBP)
developmental, female, male
84-74-2
December 2, 2005
Di-
n
-hexyl phthalate (DnHP)
female, male
84-75-3
December 2, 2005
m
-Dinitrobenzene
male
99-65-0
July 1, 1990
o
-Dinitrobenzene
male
528-29-0
July 1, 1990
p
-Dinitrobenzene
male
100-25-4
July 1, 1990
Dinitrotoluene (technical grade)
female, male
--
August 20, 1999
2,4-Dinitrotoluene
male
121-14-2
August 20, 1999
2,6-Dinitrotoluene
male
606-20-2
August 20, 1999
Dinocap
developmental
39300-45-3
April 1, 1990
Dinoseb
developmental, male
88-85-7
January 1, 1989
Diphenylhydantoin (Phenytoin)
developmental
57-41-0
July 1, 1987
Disodium cyanodithioimidocarbonate
developmental
138-93-2
March 30, 1999
Doxorubicin hydrochloride (Adriamycin)
developmental, male
25316-40-9
January 29, 1999
Doxycycline (internal use)
developmental
564-25-0
July 1, 1990
Doxycycline calcium (internal use)
developmental
94088-85-4
January 1, 1992
Doxycycline hyclate (internal use)
developmental
24390-14-5
October 1, 1991
Doxycycline monohydrate (internal use)
developmental
17086-28-1
October 1, 1991
Endrin
developmental
72-20-8
May 15, 1998
Environmental tobacco smoke (ETS)
developmental
--
June 9, 2006
Epichlorohydrin
male
106-89-8
September 1, 1996
Ergotamine tartrate
developmental
379-79-3
April 1, 1990
Estropipate
developmental
7280-37-7
August 26, 1997
Ethionamide
developmental
536-33-4
August 26, 1997
Ethyl alcohol in alcoholic beverages
developmental
--
October 1, 1987
Ethyl dipropylthiocarbamate
developmental
759-94-4
April 27, 1999
Ethylene dibromide
developmental, male
106-93-4
May 15, 1998
Ethylene glycol (ingested)
developmental
107-21-1
June 19, 2015
Ethylene glycol monoethyl ether
developmental, male
110-80-5
January 1, 1989
Ethylene glycol monoethyl ether acetate
developmental, male
111-15-9
January 1, 1993
Ethylene glycol monomethyl ether
developmental, male
109-86-4
January 1, 1989
Ethylene glycol monomethyl ether acetate
developmental, male
110-49-6
January 1, 1993
Ethylene oxide
female
75-21-8
February 27, 1987
developmental, male
August 7, 2009
Ethylene thiourea
developmental
96-45-7
January 1, 1993
Etodolac
developmental, female
41340-25-4
August 20, 1999
Etoposide
developmental
33419-42-0
July 1, 1990
Etretinate
developmental
54350-48-0
July 1, 1987
Fenoxaprop ethyl
developmental
66441-23-4
March 26, 1999
Filgrastim
developmental
121181-53-1
February 27, 2001
Fluazifop butyl
developmental
69806-50-4
November 6, 1998
Flunisolide
developmental, female
3385-03-3
May 15, 1998
Fluorouracil
developmental
51-21-8
January 1, 1989
Fluoxymesterone
developmental
76-43-7
April 1, 1990
Flurazepam hydrochloride
developmental
1172-18-5
October 1, 1992
Flurbiprofen
developmental, female
5104-49-4
August 20, 1999
Flutamide
developmental
13311-84-7
July 1, 1990
Fluticasone propionate
developmental
80474-14-2
May 15, 1998
Fluvalinate
developmental
69409-94-5
November 6, 1998
Ganciclovir
developmental, male
82410-32-0
August 26, 1997
Ganciclovir sodium
developmental, male
107910-75-8
August 26, 1997
Gemfibrozil
female, male
25812-30-0
August 20, 1999
Goserelin acetate
developmental, female, male
65807-02-5
August 26, 1997
Halazepam
developmental
23092-17-3
July 1, 1990
Halobetasol propionate
developmental
66852-54-8
August 20, 1999
Haloperidol
developmental, female
52-86-8
January 29, 1999
Halothane
developmental
151-67-7
September 1, 1996
Heptachlor
developmental
76-44-8
August 20, 1999
Hexachlorobenzene
developmental
118-74-1
January 1, 1989
Hexafluoroacetone
male
684-16-2
August 1, 2008
Hexamethylphosphoramide
developmental, male
680-31-9
October 1, 1994
n
-Hexane
male
110-54-3
December 15, 2017
2,5-Hexanedione
male
110-13-4
December 4, 2015
Histrelin acetate
developmental
--
May 15, 1998
Hydramethylnon
developmental, male
67485-29-4
March 5, 1999
Hydrogen cyanide (HCN)
male
--
July 5, 2013
and cyanide salts (CN salts)
Hydroxyurea
developmental
127-07-1
May 1, 1997
Idarubicin hydrochloride
developmental, male
57852-57-0
August 20, 1999
Ifosfamide
developmental
3778-73-2
July 1, 1990
Iodine-131
developmental
10043-66-0
January 1, 1989
Isotretinoin
developmental
4759-48-2
July 1, 1987
Lead
developmental, female, male
--
February 27, 1987
Leuprolide acetate
developmental, female, male
74381-53-6
August 26, 1997
Levodopa
developmental
59-92-7
January 29, 1999
Levonorgestrel implants
female
797-63-7
May 15, 1998
Linuron
developmental
330-55-2
March 19, 1999
Lithium carbonate
developmental
554-13-2
January 1, 1991
Lithium citrate
developmental
919-16-4
January 1, 1991
Lorazepam
developmental
846-49-1
July 1, 1990
Lovastatin
developmental
75330-75-5
October 1, 1992
Mebendazole
developmental
31431-39-7
August 20, 1999
Medroxyprogesterone acetate
developmental
71-58-9
April 1, 1990
Megestrol acetate
developmental
595-33-5
January 1, 1991
Melphalan
developmental
148-82-3
July 1, 1990
Menotropins
developmental
9002-68-0
April 1, 1990
Meprobamate
developmental
57-53-4
January 1, 1992
Mercaptopurine
developmental
6112-76-1
July 1, 1990
Mercury and mercury compounds
developmental
--
July 1, 1990
Methacycline hydrochloride
developmental
3963-95-9
January 1, 1991
Metham sodium
developmental
137-42-8
May 15, 1998
Methanol
developmental
67-56-1
March 16, 2012
Methazole
developmental
20354-26-1
December 1, 1999
Methimazole
developmental
60-56-0
July 1, 1990
Methotrexate
developmental
59-05-2
January 1, 1989
Methotrexate sodium
developmental
15475-56-6
April 1, 1990
Methyl bromide as a structural fumigant
developmental
74-83-9
January 1, 1993
Methyl chloride
developmental
74-87-3
March 10, 2000
male
August 7, 2009
Methyl isobutyl ketone (MIBK)
developmental
108-10-1
March 28, 2014
Methyl isocyanate (MIC)
developmental, male
624-83-9
November 12, 2010
Methyl mercury
developmental
--
July 1, 1987
Methyl-n-butyl ketone
male
591-78-6
August 7, 2009
developmental
December 4, 2015
N-Methylpyrrolidone
developmental
872-50-4
June 15, 2001
Methyltestosterone
developmental
58-18-4
April 1, 1990
Metiram
developmental
9006-42-2
March 30, 1999
Midazolam hydrochloride
developmental
59467-96-8
July 1, 1990
Minocycline hydrochloride (internal use)
developmental
13614-98-7
January 1, 1992
Misoprostol
developmental
59122-46-2
April 1, 1990
Mitoxantrone hydrochloride
developmental
70476-82-3
July 1, 1990
Molinate
developmental, female, male
2212-67-1
December 11, 2009
Myclobutanil
developmental, male
88671-89-0
April 16, 1999
Nabam
developmental
142-59-6
March 30, 1999
Nafarelin acetate
developmental
86220-42-0
April 1, 1990
Neomycin sulfate (internal use)
developmental
1405-10-3
October 1, 1992
Netilmicin sulfate
developmental
56391-57-2
July 1, 1990
Nickel carbonyl
developmental
13463-39-3
September 1, 1996
Nickel (soluble compounds)
developmental, male
--
October 26, 2018
Nicotine
developmental
54-11-5
April 1, 1990
Nifedipine
developmental, female, male
21829-25-4
January 29, 1999
Nimodipine
developmental
66085-59-4
April 24, 2001
Nitrapyrin
developmental
1929-82-4
March 30, 1999
Nitrobenzene
male
98-95-3
March 30, 2010
Nitrofurantoin
male
67-20-9
April 1, 1991
Nitrogen mustard (Mechlorethamine)
developmental
51-75-2
January 1, 1989
Nitrogen mustard hydrochloride (Mechlorethamine
							 hydrochloride)
developmental
55-86-7
July 1, 1990
Nitrous oxide
developmental, female
10024-97-2
August 1, 2008
Norethisterone (Norethindrone)
developmental
68-22-4
April 1, 1990
Norethisterone acetate (Norethindrone acetate)
developmental
51-98-9
October 1, 1991
Norethisterone (Norethindrone)/Ethinyl estradiol
developmental
68-22-4/57-63-6
April 1, 1990
Norethisterone (Norethindrone)/Mestranol
developmental
68-22-4/72-33-3
April 1, 1990
Norgestrel
developmental
6533-00-2
April 1, 1990
Oxadiazon
developmental
19666-30-9
May 15, 1998
Oxazepam
developmental
604-75-1
October 1, 1992
Oxydemeton methyl
female, male
301-12-2
November 6, 1998
Oxymetholone
developmental
434-07-1
May 1, 1997
Oxytetracycline (internal use)
developmental
79-57-2
January 1, 1991
Oxytetracycline hydrochloride (internal use)
developmental
2058-46-0
October 1, 1991
Oxythioquinox (Chinomethionat)
developmental
2439-01-2
November 6, 1998
Paclitaxel
developmental, female, male
33069-62-4
August 26, 1997
Paramethadione
developmental
115-67-3
July 1, 1990
Penicillamine
developmental
52-67-5
January 1, 1991
Pentobarbital sodium
developmental
57-33-0
July 1, 1990
Pentostatin
developmental
53910-25-1
September 1, 1996
Perfluorononanoic acid (PFNA) and its salts
male
-
December 31, 2021
Perfluorooctane 9ulfonate (PFOS)
developmental
1763-23-1
November 10, 2017
Perfluorooctanoic acid (PFOA)
developmental
335-67-1
November 10, 2017
Pertuzumab
developmental
380610-27-5
January 27, 2017
Phenacemide
developmental
63-98-9
July 1, 1990
Phenprocoumon
developmental
435-97-2
October 1, 1992
Phenylphosphine
male
638-21-1
August 7, 2009
Pimozide
developmental, female
2062-78-4
August 20, 1999
Pipobroman
developmental
54-91-1
July 1, 1990
Plicamycin
developmental
18378-89-7
April 1, 1990
Polybrominated biphenyls
developmental
--
October 1, 1994
Polychlorinated biphenyls
developmental
--
January 1, 1991
Potassium dimethyldithiocarbamate
developmental
128-03-0
March 30, 1999
Pravastatin sodium
developmental
81131-70-6
March 3, 2000
Prednisolone sodium phosphate
developmental
125-02-0
August 20, 1999
Procarbazine hydrochloride
developmental
366-70-1
July 1, 1990
Propargite
developmental
2312-35-8
June 15, 1999
Propazine
developmental, female
139-40-2
July 15, 2016
Propylthiouracil
developmental
51-52-5
July 1, 1990
Pyrimethamine
developmental
58-14-0
January 29, 1999
Quazepam
developmental
36735-22-5
August 26, 1997
Quizalofop-ethyl
male
76578-14-8
December 24, 1999
Resmethrin
developmental
10453-86-8
November 6, 1998
Retinol/retinyl esters, when in daily dosages in excess
							 of 10,000 IU, or 3,000 retinol equivalents. (NOTE: Retinol/retinyl esters are
							 required and essential for maintenance of normal reproductive function. The
							 recommended daily level during pregnancy is 8,000 IU.)
developmental
--
July 1, 1989
Ribavirin
developmental
36791-04-5
April 1, 1990
male
36791-04-5
February 27, 2001
Rifampin
developmental, female
13292-46-1
February 27, 2001
Secobarbital sodium
developmental
309-43-3
October 1, 1992
Sermorelin acetate
developmental
--
August 20, 1999
Simazine
developmental, female
122-34-9
July 15, 2016
Sodium dimethyldithiocarbamate
developmental
128-04-1
March 30, 1999
Sodium fluoroacetate
male
62-74-8
November 6, 1998
Streptomycin sulfate
developmental
3810-74-0
January 1, 1991
Streptozocin (streptozotocin)
developmental, female, male
18883-66-4
August 20, 1999
Sulfasalazine (Salicylazosulfapyridine)
male
599-79-1
January 29, 1999
Sulfur dioxide
developmental
7446-09-5
July 29, 2011
Sulindac
developmental, female
38194-50-2
January 29, 1999
Tamoxifen citrate
developmental
54965-24-1
July 1, 1990
Temazepam
developmental
846-50-4
April 1, 1990
Teniposide
developmental
29767-20-2
September 1, 1996
Terbacil
developmental
5902-51-2
May 18, 1999
Testosterone cypionate
developmental
58-20-8
October 1, 1991
Testosterone enanthate
developmental
315-37-7
April 1, 1990
2,3,7,8-Tetrachlorodibenzo-
p
-dioxin
							 (TCDD)
developmental
1746-01-6
April 1, 1991
Tetracycline (internal use)
developmental
60-54-8
October 1, 1991
Tetracyclines (internal use)
developmental
--
October 1, 1992
Tetracycline hydrochloride (internal use)
developmental
64-75-5
January 1, 1991
[DELTA]9-Tetrahydrocannabinol
							 ([DELTA]9-THC; delta-9-THC)
developmental
--
January 3, 2020
Thalidomide
developmental
50-35-1
July 1, 1987
Thioguanine
developmental
154-42-7
July 1, 1990
Thiophanate methyl
female, male
23564-05-8
May 18, 1999
Tobacco smoke (primary)
developmental, female, male
--
April 1, 1988
Tobramycin sulfate
developmental
49842-07-1
July 1, 1990
Toluene
developmental
108-88-3
January 1, 1991
Topiramate
developmental
97240-79-4
November 27, 2015
Triadimefon
developmental, female, male
43121-43-3
March 30, 1999
Triazolam
developmental
28911-01-5
April 1, 1990
Tributyltin methacrylate
developmental
2155-70-6
December 1, 1999
Trichloroethylene
developmental, male
79-01-6
January 31, 2014
Trientine hydrochloride
developmental
38260-01-4
February 27, 2001
Triforine
developmental
26644-46-2
June 18, 1999
Trilostane
developmental
13647-35-3
April 1, 1990
Trimethadione
developmental
127-48-0
January 1, 1991
Trimetrexate glucuronate
developmental
82952-64-5
August 26, 1997
Triphenyltin hydroxide
developmental
76-87-9
March 15, 2002
Uracil mustard
developmental, female, male
66-75-1
January 1, 1992
Urethane
developmental
51-79-6
October 1, 1994
Urofollitropin
developmental
97048-13-0
April 1, 1990
Valproate (Valproic acid)
developmental
99-66-1
July 1, 1987
Vinblastine sulfate
developmental
143-67-9
July 1, 1990
Vinclozolin
developmental
50471-44-8
May 15, 1998
Vincristine sulfate
developmental
2068-78-2
July 1, 1990
4-Vinylcyclohexene
female
100-40-3
August 7, 2009
Vinyl cyclohexene dioxide (4-Vinyl-l-cyclohexene
							 diepoxide)
female
106-87-6
August 1, 2008
Visomodegib
developmental, female, male
879085-55-9
January 27, 2017
Warfarin
developmental
81-81-2
July 1, 1987
Zileuton
developmental, female
111406-87-2
December 22, 2000
Date: December 29, 2023
Note: Authority cited: Section 25249.8, Health and Safety
						Code. Reference: Section 25249.8, Health and Safety Code.
Note: Authority
					 cited: Section
					 25249.8,
					 Health and Safety Code. Reference: Section
					 25249.8,
					 Health and Safety Code.