California Code of Regulations › Title 27 - Environmental Protection › Division 4 - Office of Environmental Health Hazard Assessment › Chapter 1 - Safe Drinking Water and Toxic Enforcement Act of 1986 › Article 9 - Miscellaneous › Section 27000 - Chemicals Required by State or Federal Law to Have Been Tested for Potential to Cause Cancer or Reproductive Toxicity, but Which Have Not Been Adequately Tested as Required

Current through Register 2024 Notice Reg. No. 28, July 12, 2024
(a) The Safe
					 Drinking Water and Toxic Enforcement Act of 1986 requires the Governor to
					 publish a list of chemicals formally required by state or federal agencies to
					 have testing for carcinogenicity or reproductive toxicity, but that the state's
					 qualified experts have not found to have been adequately tested as required
					 [Health and Safety Code Section
					 25249.8(c)].
(b) Chemicals required to be tested by the
					 California Department of Pesticide Regulation.
(1) The Birth Defect Prevention Act of 1984
					 (SB 950) mandates that the California Department of Pesticide Regulation (CDPR)
					 review chronic toxicology studies supporting the registration of pesticidal
					 active ingredients. Missing or unacceptable studies are identified as data
					 gaps.
(2) The studies are conducted
					 to fulfill generic data requirements of the Federal Insecticide, Fungicide, and
					 Rodenticide Act (FIFRA), which is administered by the United States
					 Environmental Protection Agency (U.S. EPA).
(3) The studies are reviewed by CDPR
					 according to guidelines and standards promulgated under FIFRA. Older studies
					 may not meet current guidelines.
(4) The existence of a data gap for a
					 compound does not indicate a total lack of information on the carcinogenicity
					 or reproductive toxicity of the compound. In some cases, information exists in
					 the open scientific literature, but SB 950 requires specific additional
					 information.
(5) A data gap does
					 not necessarily indicate that an oncogenic or reproductive hazard exists. For
					 the purposes of this list, a data gap is still considered to be present until
					 the study is reviewed and found to be acceptable.
(6) Following is a listing of SB 950 data
					 gaps for oncogenicity, reproduction, and teratology studies for pesticidal
					 active ingredients. This list changes as data gaps are filled by additional
					 data or replacement studies.
(7)
					 For purposes of this section, "onc mouse" means oncogenicity in mice, "onc rat"
					 means oncogenicity in rats, "repro" means reproduction, "tera rat" means
					 teratogenicity in rats, "tera rabbit" means teratogenicity in rabbits.
Chemical
Testing Needed
Acid Blue 9*
onc rat, onc mouse, repro, tera rat, tera
					 rabbit
Acid Yellow
					 23*
onc rat, onc mouse, repro, tera rat, tera rabbit
Butoxy polypropylene glycol*
onc
					 rat, onc mouse, repro, tera rat, tera rabbit
Butoxy polypropoxy polyethoxy ethanol--iodine
					 complex*
onc rat, onc mouse, repro, tera rat, tera rabbit
Castor oil*
onc rat, onc
					 mouse, repro, tera rat, tera rabbit
Chlorophacinone*
onc rat, onc mouse, repro
Chromic acid*
onc rat, onc mouse,
					 repro, tera rabbit
Menthol*
onc rat, onc mouse, repro, tera rat, tera rabbit
Meta-cresol*
tera rat,
					 onc rat, onc mouse, repro, tera rabbit
Sodium chlorate*
onc rat, onc mouse, repro, tera rat,
					 tera rabbit
Sodium
					 phenate*
onc rat, onc mouse, repro, tera rat, tera rabbit
Tetraglycine hydroperiodide*
onc rat, onc mouse, repro, tera rat, tera rabbit
2,4-Xylenol*
onc rat, onc mouse, repro, tera
					 rat, tera rabbit
* Claims are pending review that data should not be
					 required.
** No product containing this active
					 ingredient is registered with CDPR.