Illinois Administrative Code › Title 77 - PUBLIC HEALTH › Part 995 - ILLINOIS REGENERATIVE MEDICINE INSTITUTE CODE › Section 995.10 - Definitions

Current through Register Vol. 48, No. 28, July 12, 2024
"Androgenetic human embryos" means embryos created from a male
				spermatozoon without genetic contribution from a female.
"Applicant" means an eligible institution that has submitted an
				application for an award of a grant pursuant to this Part for the purpose of
				conducting stem cell research in Illinois.
"Biotechnology start-up company" means a new company that makes
				use of microorganisms to achieve a result.
"Blastocyst" means a preimplantation embryo of 30-100 cells.
				The blastocyst consists of a sphere made up of an outer layer of cells (the
				trophectoderm), a fluid-filled cavity (the blastocoel), and a cluster of cells
				on the interior (the inner cell mass).
"Cell division" means a method by which a single cell divides
				to create two cells. This continuous process allows a population of cells to
				increase in number or maintain its numbers.
"Chimera" means an organism derived from more than one
				fertilized cell.
"Department" means the Illinois Department of Public
				Health.
"Differentiated cell" means a cell in which the level of
				organization or complexity has developed into a specialized function.
"Embryo" means a fertilized ovum from the time of fertilization
				until the end of the eighth week of gestation.
"Embryonic stem cell research" means research on embryonic stem
				cells.
"Embryonic stem cells" means pluripotent stem cells derived
				from the inner cell mass of a blastocyst that have the potential to become a
				wide variety of specialized cell types.
"ESCRO committee" means the Embryonic Stem Cell Research
				Oversight committee that provides ethical and legal oversight at institutions
				working with human embryonic stem cell lines.
"Experiment" means a test under controlled conditions that is
				made to demonstrate a known truth, to examine the validity of a hypothesis, or
				to determine the efficacy of something previously untried.
"FDA" means the United States Food and Drug
				Administration.
"Gamete" means a sperm or oocyte.
"Grant" means the award of funds under the Illinois
				Regenerative Medicine Institute (IRMI) program to an eligible applicant to
				conduct stem cell research in Illinois.
"Grant agreement" means the agreement entered into between the
				Department and a grantee setting forth the terms and conditions of a grant
				award.
"Grantee" means an institution receiving a grant.
"HIPAA" means the Health Insurance Portability and
				Accountability Act of 1996 and the Standards for Privacy of Individually
				Identified Health Information (Privacy Rule).
"Human embryonic stem cells" means embryonic stem cells derived
				from a human blastocyst.
"Human subject" means a living individual from whom an
				investigator, whether professional or student, conducting research obtains data
				or tissue through either intervention or interaction with the individual, or
				identifiable private information.
"Illinois Regenerative Medicine Institute" or "IRMI" or the
				"Institute" means a program of the Department to award research grants.
"Illinois Regenerative Medicine Institute Oversight Committee"
				or "Committee" means the group that determines the awards of the Institute's
				grant program, among other duties.
"Institution" means a corporation, association, partnership,
				nonprofit organization, governmental entity or other legal entity that conducts
				stem cell research.
"Institutional Animal Care and Use Committee" or "IACUC" means
				the committee providing oversight at an institution that uses animals as part
				of federally funded laboratory research.
"Institutional Research Committee" or "IRC" means the committee
				appointed by an institution to provide continuing oversight of the activities
				of an IRMI funded project.
"Institutional Review Board" or "IRB" means any board,
				committee or other group formally designated by an institution to conduct an
				initial review of, to approve the initiation of, and to conduct periodic review
				of all biomedical research involving human subjects.
"Intellectual property" means a creation of the mind that is
				unique, novel and unobvious, and has commercial value.
"Investigator" means a person conducting or assisting in the
				performance of stem cell research.
"In vitro" means a process or reaction occurring in an
				artificial environment such as a test tube or culture medium.
"In vitro fertilization" means a procedure in which
				fertilization of an egg with a sperm is accomplished outside the living
				organism.
"Lobbying" means any communication with the Governor,
				Lieutenant Governor, Secretary of State, Attorney General, State Treasurer or
				State Comptroller, their chiefs of staff, their cabinet members including
				Directors, Assistant Directors and Chief Legal Counsels or General Counsels, or
				Members of the General Assembly for the ultimate purpose of influencing
				executive, legislative or administrative action.
"Medical research" means basic or applied research conducted to
				aid the body of knowledge in the field of medicine.
"Nonprofit" means an institution exempt from taxation under
				section 501(c)(3) of the Internal Revenue Code.
"Nonprofit medical research institution" means a corporation,
				association, partnership, nonprofit organization, governmental entity or other
				legal entity that is exempt from taxation under section 501(c)(3) of the
				Internal Revenue Code and conducts basic or applied research to aid the body of
				knowledge in the field of medicine.
"Parthenogenetic human embryos" means embryos created soley
				from a female oocyte without genetic contribution from a male.
"Pluripotent" means the ability of a single stem cell to
				develop into many different cell types of the body.
"Principal investigator" means the person with primary
				responsibility for conducting a stem cell research project.
"Progenitor cell" means an early descendant of a stem cell that
				can differentiate, but cannot renew itself as a stem cell can.
"Project period" means the period in which a research project
				funded by a grant is to be completed.
"Reproductive cloning" means somatic cell nuclear transfer used
				for the production of a fetus and delivery of a live offspring that is
				genetically identical to the donor of the somatic cell DNA.
"Request for applications" or "RFA" means the announcement of
				the details of the application process for stem cell grants.
"Research donor" means an individual who donates to research
				any number of blastocysts that remain after clinical care at the time of the
				original harvesting.
"Scientific Review Panel" or "Panel" means a group of stem cell
				researchers from outside Illinois, chosen by the Department.
"Somatic cell nuclear transfer" means a technique in which the
				nucleus of a somatic cell is injected or transferred into an egg that has had
				its nucleus removed.
"Somatic stem cell", also called adult stem cell, means an
				undifferentiated cell that can become a specialized cell type of the tissue
				from which it came.
"Stem cell" means a cell with the ability to divide for
				indefinite periods in culture and to give rise to specialized cells, and
				includes, without limitation, somatic stem cells, cord blood stem cells,
				pluripotent stem cells, totipotent stem cells, progenitor cells, the product of
				somatic cell nuclear transfer, and any combination of these cells.
"Stem cell line" means a family of constantly dividing cells,
				the product of a single parent group of stem cells.
"Stem cell research" means scientific investigation and study
				into the nature and properties of stem cells, the transformation of stem cells
				into specialized cells, the development of stem cell lines, the growth of stem
				cells in vitro, or the possible uses of stem cells to cure or reduce the
				effects of disease, disabilities or physical conditions or maladies.
"TIN" means the nine-digit federal taxpayer identification
				number assigned to an institution by the Internal Revenue Service, also known
				as the federal employer identification number or governmental unit code.
"Totipotent stem cell" means a cell that can give rise to all
				cell types that are found in an embryo, fetus or developed organism, including
				the embryonic components of the trophoblast and placenta required to support
				development and birth. The zygote and the cells at the very early stages
				following fertilization are considered totipotent.
"Undifferentiated cell" means a cell in which the level of
				organization or complexity has not yet developed into a specialized
				function.