California Code of Regulations › Title 8 - Industrial Relations › Division 1 - Department of Industrial Relations › Chapter 4 - Division of Industrial Safety › Subchapter 7 - General Industry Safety Orders › Group 16 - Control of Hazardous Substances › Article 110 - Regulated Carcinogens › Appendix A to Section 5200 - Substance Data Sheet for 4-4'-Methylenedianiline

Current through Register 2024 Notice Reg. No. 28, July 12, 2024
I. SUBSTANCE IDENTIFICATION
A. Substance: Methylenedianiline (MDA)
B. Permissible Exposure:
1. Airborne: Ten parts per billion parts of air (10
						  ppb), time- weighted average (TWA) for an 8-hour workday and an action level of
						  five parts per billion parts of air (5 ppb).
2. Dermal: Eye contact and skin contact with MDA are
						  not permitted.
C. Appearance and odor: White to tan solid; amine
						  odor
II. HEALTH HAZARD DATA
A. Ways in which MDA affects your health. MDA can
						  affect your health if you inhale it, or if it comes in contact with your skin
						  or eyes. MDA is also harmful if you happen to swallow it. Do not get MDA in
						  eyes, on skin, or on clothing.
B. Effects of overexposure.
1. Short-term (acute) overexposure: Overexposure to MDA
						  may produce fever, chills, loss of appetite, vomiting, jaundice. Contact may
						  irritate skin, eyes and mucous membranes. Sensitization may occur.
2. Long-term (chronic) exposure. Repeated or prolonged
						  exposure to MDA, even at relatively low concentrations, may cause cancer. In
						  addition, damage to the liver, kidneys, blood, and spleen may occur with long
						  term exposure.
3. Reporting signs and symptoms: You should inform your
						  employer if you develop any signs or symptoms which you suspect are caused by
						  exposure to MDA including yellow staining of the skin.
III. PROTECTIVE CLOTHING AND EQUIPMENT
A. Respirators. Respirators are required for those
						  operations in which engineering controls or work practice controls are not
						  adequate or feasible to reduce exposure to the permissible limit. If
						  respirators are worn, they must have a label issued by the National Institute
						  for Occupational Safety and Health (NIOSH) under the provisions of 42 CFR part
						  84 stating that the respirators have been approved for this purpose, and
						  cartridges or canisters must be replaced in accordance with the requirements of
						  section 5144. If you experience difficulty
						  breathing while wearing a respirator, you may request a positive pressure
						  respirator from your employer. You must be thoroughly trained to use the
						  assigned respirator, and the training will be provided by your employer.
MDA does not have a detectable odor except at levels
						  well above the permissible exposure limits. Do not depend on odor to warn you
						  when a respirator canister is exhausted. If you can smell MDA while wearing a
						  respirator, proceed immediately to fresh air. If you experience difficulty
						  breathing while wearing a respirator, tell your employer.
B. Protective clothing. You may be required to wear
						  coveralls, aprons, gloves, face shields, or other appropriate protective
						  clothing to prevent skin contact with MDA. Where protective clothing is
						  required, your employer is required to provide clean garments to you, as
						  necessary, to assure that the clothing protects you adequately. Replace or
						  repair impervious clothing that has developed leaks.
MDA should never be allowed to remain on the skin.
						  Clothing and shoes which are not impervious to MDA should not be allowed to
						  become contaminated with MDA, and if they do, the clothing and shoes should be
						  promptly removed and decontaminated. The clothing should be laundered to remove
						  MDA or discarded. Once MDA penetrates shoes or other leather articles, they
						  should not be worn again.
C. Eye protection. You must wear splashproof safety
						  goggles in areas where liquid MDA may contact your eyes. Contact lenses should
						  not be worn in areas where eye contact with MDA can occur. In addition, you
						  must wear a face shield if your face could be splashed with MDA liquid.
IV. EMERGENCY AND FIRST AID PROCEDURES
A. Eye and face exposure. If MDA is splashed into the
						  eyes, wash the eyes for at least 15 minutes. See a doctor as soon as
						  possible.
B. Skin exposure. If MDA is spilled on your clothing or
						  skin, remove the contaminated clothing and wash the exposed skin with large
						  amounts of soap and water immediately. Wash contaminated clothing before you
						  wear it again.
C. Breathing. If you or any other person breathes in
						  large amounts of MDA, get the exposed person to fresh air at once. Apply
						  artificial respiration if breathing has stopped. Call for medical assistance or
						  a doctor as soon as possible. Never enter any vessel or confined space where
						  the MDA concentration might be high without proper safety equipment and at
						  least one other person present who will stay outside. A life line should be
						  used.
D. Swallowing. If MDA has been swallowed and the
						  patient is conscious, do not induce vomiting. Call for medical assistance or a
						  doctor immediately.
V. MEDICAL REQUIREMENTS
If you are exposed to MDA at a concentration at or
						  above the action level for more than 30 days per year, or exposed to liquid
						  mixtures more than 15 days per year, your employer is required to provide a
						  medical examination, including a medical history and laboratory tests, within
						  60 days of the effective date of this standard and annually thereafter. These
						  tests shall be provided without cost to you. In addition, if you are
						  accidentally exposed to MDA (either by ingestion, inhalation, or skin/eye
						  contact) under conditions known or suspected to constitute toxic exposure to
						  MDA, your employer is required to make special examinations and tests available
						  to you.
VI. OBSERVATION OF MONITORING
Your employer is required to perform measurements that
						  are representative of your exposure to MDA and you or your designated
						  representative are entitled to observe the monitoring procedure. You are
						  entitled to observe the steps taken in the measurement procedure and to record
						  the results obtained. When the monitoring procedure is taking place in an area
						  where respirators or personal protective clothing and equipment are required to
						  be worn, you and your representative must also be provided with, and must wear,
						  the protective clothing and equipment.
VII. ACCESS TO RECORDS
You or your representative are entitled to see the
						  records of measurements of your exposure to MDA upon written request to your
						  employer. Your medical examination records can be furnished to your physician
						  or designated representative upon request by you to your employer.
VIII. PRECAUTIONS FOR SAFE USE, HANDLING AND
						  STORAGE
A. Material is combustible. Avoid strong acids and
						  their anhydrides. Avoid strong oxidants. Consult supervisor for disposal
						  requirements.
B. Emergency clean-up. Wear self-contained breathing
						  apparatus and fully clothe the body in the appropriate personal protective
						  clothing and equipment.