Conversation so far:
Is Hamid Karzai married?
Hamid Karzai married Zeenat Quraishi.
When were they married?
In 1999.
What did his wife do?
Zeenat Quraishi, a gynaecologist by profession who was working as a doctor with Afghan refugees living in Pakistan.

Question: Did they have any children?
Self-contained rewrite: Did Hamid Karzai and Zeenat Quraishi have any children?