Conversation so far:
What did Isabella I of Castile do in her later years?
Isabella received the title of Catholic Monarch by Pope Alexander VI
Why did Isabella I of Castile receive the title of the title of Catholic Monarch by Pope Alexander VI?
Isabella I Queen of Castile embarked on a process of spiritual unification, trying to bring the country under one faith
Was the process of spiritual unification and trying to bring the country under one faith a successful endeavor?
the Treaty of Granada was broken in 1502
Why was the treaty of Granada broken in 1502?
After a Muslim uprising in 1499, and further troubles thereafter.

Question: What other troubles were there?
Self-contained rewrite: What other troubles were there besides the Muslim uprising in 1499 that broke the treaty of Granada in 1502?