Conversation so far:
What was Lionel Barrymore's main medical issue?
arthritis.
How did it affect him?
confined Barrymore to a wheelchair.
Was it always severe?
A history of Oscar-winning actors, however, says Barrymore was only suffering from arthritis, not crippled by it.

Question: Was he cripped by the pain or limited movement?
Self-contained rewrite: Was Lionel Barrymore crippled by the pain of arthritis or limited movement?