Conversation so far:
What did Pfeiffer do in Michelle Pfeiffer's career between 2000-2006?
In the Hitchcockian thriller What Lies Beneath (2000), Pfeiffer and Harrison Ford starred as a well-to-do couple who experience a strange haunting that uncovers secrets about their past.
What film did she star in after Hitchockian?
She then accepted the role of Rita Harrison, a highly strung lawyer helping a father with a developmental disability, in the drama I Am Sam (2001), opposite Sean Penn.
Did she win any awards for movies shee stared in between 2000-2006?
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She earned Best Supporting Actress Awards from the San Diego Film Critics Society and the Kansas City Film Critics Circle, as well as a Screen Actors Guild Award nomination.
Did she produce any of her award winning movies or play a job role in directing?
Pfeiffer chose to begin the process of dissolving her film production company, Via Rosa Productions, in 1999.
Did she act in the film Via Rosa?
Pfeiffer handed her producing partner Guinzburg one final film to produce under the Via Rosa Productions header.

Question: What was her biggest film and total money made in that time period?
Self-contained rewrite: What was Michelle Pfeiffer's biggest film and total money made in 2000-2006?