Conversation so far:
What happened tot he fur trade in the 18th century?
Deerskin trade was at its most profitable in the mid-18th century.
Where did the deer skin come from?
Native Americans continued to negotiate the most lucrative trade deals by forcing England, France, and Spain to compete for their supply of deerskins.
What tactics were used by the Native Americans?
the Cherokee and the Creek were the main trading partners of the British, their relationships with the British were different.
What was different about their relationship with the British?
The Creeks adapted to the new economic trade system, and managed to hold onto their old social structures.
Were there any wars at the time?
CANNOTANSWER.
Are there any other interesting aspects about this article?
Charleston and Savannah were the main trading ports for the export of deerskins.
Who controlled those ports?
Charleston's trade was regulated by the Indian Trade Commission, composed of traders who monopolized the market.
How did they control the market?
CANNOTANSWER.

Question: What else was happening at this time?
Self-contained rewrite: Besides the Indian Trade Commission controlling the market, what else was happening in the mid-18th century?