Conversation so far:
What health problems did Tierney have?
Tierney struggled for years with episodes of manic depression.
Besides depression, did Tierney have any other health problems?
She subsequently became a heavy smoker.
What health problems were the cause of her death?
CANNOTANSWER.

Question: Besides smoking and depression, she she have any other health issues?
Self-contained rewrite: Besides smoking and depression, did Gene Tierney have any other health issues?