Conversation so far:
what was the name of the country charles v had the most issue with?
From 1515 to 1523, Charles's government in the Netherlands also had to contend with the rebellion of Frisian peasants.
what year did he have his conflict with his nemisis?
The rebels were initially successful but after a series of defeats, the remaining leaders were captured and decapitated in 1523.

Question: did France concur Milan?
Self-contained rewrite: Was Milan conquered by France?