Conversation so far:
What did Isabella I of Castile do in Isabella I of Castile's later years?
Isabella received the title of Catholic Monarch by Pope Alexander VI.
Why did she receive this title?
Isabella and Ferdinand embarked on a process of spiritual unification, trying to bring the country under one faith.
Was this a successful endeavor?
Treaty of Granada was broken in 1502.
Why was it broken?
After a Muslim uprising in 1499, and further troubles.

Question: What other troubles were there?
Self-contained rewrite: What other troubles were there with the Treaty of Granada other than the Muslim uprising?