Conversation so far:
Who was Bill W. married to?
Lois Burnham
Did Bill W. and Lois Bumham have any kids?
When did Bill W. and Lois Bumham get married?
Wilson married Lois on January 24, 1918.
Where did Bill W. work?
Wilson became a stock speculator and had success traveling the country with his wife, evaluating companies for potential investors.
When did Bill W. start struggling with alcoholism?
1916
How did alcohol impact Bill W.'s life?
Wilson's constant drinking made business impossible and ruined his reputation.

Question: Did alcohol affect his marriage?
Self-contained rewrite: Did alcohol affect Bill W.'s marriage?