Conversation so far:
Who is Fliess?
his friend Wilhelm Fliess, a Berlin based ear, nose and throat specialist whom he had first met 1887.
What was their relationship?
Freud valued and came to rely on the intellectual and emotional support.
Did they collaborate?
They maintained an extensive correspondence from which Freud drew on Fliess's speculations on infantile sexuality and bisexuality to elaborate and revise his own ideas.
How else did Fliess influence him?
Both men saw themselves as isolated from the prevailing clinical and theoretical mainstream because of their ambitions to develop radical new theories of sexuality.
What did they accomplish together?
Their friendship came to an acrimonious end with Fliess angry at Freud's unwillingness to endorse his general theory of sexual periodicity.

Question: What happened after this?
Self-contained rewrite: What happened after Fliess became angry and Freud's unwillingness to endorse his general theory of sexual periodicity?