Conversation so far:
What year did Isabella I of Castile die?
Isabella I of Castile officially withdrew from governmental affairs on 14 September 1504 and she died that same year on 26 November at the Medina del Campo Royal Palace.
What did Isabella I of Castile do in her later life?
Isabella received the title of Catholic Monarch by Pope Alexander VI.
What year was it for Isabella I of Castile received the title of Catholic Monarch?

Question: why did she not approve
Self-contained rewrite: Why did Isabella I of Castile not approve of Alexander VI giving her the title Catholic Monarch?