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What wars were the Powhatan involved in?
The Powhatan people were involved in the First Anglo-Powhatan War.
What was the First Anglo-Powhatan War about?
Powhatan ordered something like a siege of Jamestown. This was the Indians' best chance to win the war, but the English survived and, after the arrival of reinforcements, viciously attacked.

Question: Were they involved in any other wars?
Self-contained rewrite: Were the Powhatan involved in any other wars besides the First Anglo-Powhatan War?