Conversation so far:
What is Edwin Booth's father's name?
Edwin Booth's father was Junius Brutus Bruth.
What did Edwin Booth perform in first?
Edwin Booth's stage debut was as Tressel or Tressil in Colley Cibber's version of Richard III in Boston.
What happened to Edwin Booth after his initial debut in the play, Richard III?
Edwin Booth's first appearance in New York City as Wilford in The Iron Chest, which he played at the National Theatre in Chatham Street, on the 27th of September 1850.
Where did Edwin Booth go for the play, The Iron Chest?
Edwin Booth played at the National Theatre in Chatham Street.
Did Edwin Booth ever perform with John Wilkes?
Before his brother assassinated Lincoln, Edwin Booth had appeared with his two brothers, John Wilkes and Junius Brutus Booth Jr., in Julius Caesar in 1864.

Question: What play
Self-contained rewrite: What play did Edwin Booth perform with John Wilkes?