Conversation so far:
Is Hamid Karzai married?
In 1999, Hamid Karzai married Zeenat Quraishi.
When were Hamid Karzai and Zeenat Quraishi married?
1999
What did Hamid Karzai's wife do?
She was a gynecologist by profession who was working as a doctor with Afghan refugees living in Pakistan.

Question: Did they have any children?
Self-contained rewrite: Did Hamid Karzai and his wife have any children?