Conversation so far:
Interesting aspects of Allen Toussaint's early life?
In his teens Allen Toussaint played in a band, the Flamingos, with the guitarist Snooks Eaglin, before dropping out of school.
Notable info on Allen Toussaint's early career?
Allen Toussaint's first recording was in 1957 as a stand-in for Fats Domino on Domino's record I Want You to Know, on which Toussaint played piano and Domino overdubbed vocals.
What were Allen Toussaint's next recordings?
Allen Toussaint's first success as a producer also came in 1957 with Lee Allen's Walking with Mr. Lee.

Question: What was the biggest hit?
Self-contained rewrite: What was the biggest hit by Allen Toussaint?