Conversation so far:
when did Humphrey Lyttelton's career first start to take off?
and formed a quartet at the school in 1936.
where did he go to school at?
From Sunningdale Preparatory School, Lyttelton duly progressed to Eton College.
what country/state was this in?
in Buckinghamshire).

Question: is there something big that changed his life?
Self-contained rewrite: Is there something big that changed Humphrey Lyttelton's life?