Conversation so far:
Who created Marge Simpson?
Marge Simpson was created and designed by cartoonist Matt Groening.
What was Matt Groening's process in creating Marge Simpson?
Marge Simpson was named after Groening's mother Margaret Marge Groening, who has said she bears little similarity to the character.
Did Matt Groening have any other inspirations for Marge Simpson's creation besides his mother?
Marge Simpson's beehive hairstyle was inspired by the titular Bride in Bride of Frankenstein and the style that Margaret Groening wore during the 1960s, although her hair was never blue.
What did Matt Groening draw on for Marge Simpson's personality?
Are there any other interesting aspects about the Marge Simpson article besides Matt Groenig's inspiration for her?
Matt Groening believes that episodes featuring Marge Simpson are among the most difficult episodes to write.

Question: What makes them difficult to write?
Self-contained rewrite: What makes the episodes of The Simpsons featuring Marge Simpson difficult to write for Matt Groening?