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On 10 November 1509, Pizarro sailed from Spain.
Where did he go?
to the New World.
Why did he want to go there?
to conquer the Incan Empire.
What did he do there?
the Battle of Cajamarca.
How did that go?
Atahualpa refused to tolerate a Spanish presence in his lands, but was captured by Pizarro.
What did Pizarro do with him?
Pizarro charged him with various crimes and executed him.
How did the locals react to that?
CANNOTANSWER.

Question: Did anyone try to overthrow him?
Self-contained rewrite: Did anyone try to overthrow Pizarro?