Conversation so far:
What was their first big hit?
The Offspring's first major single release, "Come Out and Play", which reached #1 on Billboard Modern Rock Tracks chart.
What was the second single?
The second single released from the album, "Self Esteem", became a radio hit, managing to peak at number 4 on the Billboard Modern Rock Tracks chart.
What was the song about?
The lyrics are about an abusive relationship in which the girl takes advantage of her boyfriend, as he has "no self-esteem" to stand up to her.
Was the song about the band members?
Contrary to popular belief, the song is not autobiographical.

Question: Did they say who the song was about?
Self-contained rewrite: Did The Offspring say who Self Esteem was about?