I main support, usually opting for poke supports such as Lulu and Sona or aggressive supports such as Blitzcrank and Leona. Since the various Regional Finals, however, I've begun to encounter support Zyras in my bot lane.

This is a very difficult lane for me. I can't establish lane dominance, since Zyra just sits in her bush and puts seeds in mine. I've tried a rune page with flat MR for when I play against Zyra to counter some of her harass, but it doesn't help against her cc.

How can I effectively counter a support Zyra?


Question: Why do so many people have group O blood?
Answer: There are many different variants of O (all loss-of-function) indicating that this mutation has arisen many times in the human population. The prevalence of O is indeed taken as evidence of balancing selection. Various pathogens use the A or B antigens as receptors. The cited paper presents evidence about the phylogeny of the ABO gene in human populations and reports that there is clear evidence of balancing selection.


  We propose several hypotheses for the cause of [balancing selection], which most likely involved interactions with multiple pathogens at different geographic regions and timescales.
  
  Calafell et al (2008) Evolutionary dynamics of the human ABO gene. Human Genetics 124: 123-135