I know this is a rather controversial issue. I was skeptical as well before doing this on my car, and I have not refilled my car tires for several months. Before that I needed to adjust the pressure every couple of months at least. 

Now I think it is a good idea to try this for our bikes. Especially since, when I see I need to fill up my bike tires, I get too lazy and give up the ride altogether. 

Is there a way to do this at home?

EDIT:
I thought I'd update the question for people who come and read later:  

Thanks for all the comments, I drive a lot (30kmiles/year) and I saw (to my surprise) a significant difference with nitrogen. 

I understand the reasoning with losing oxygen over time and increasing the N2 concentration but in practice that does not happen fast enough.  

I think I'll look into Helium/Argon and I'll update you if I managed to do something interesting. 

And I live in a small place I don't like to have a large pump but that is exactly why pumping is such a chore for me,


Question: Is the Mechromancer's Little Big Trouble tree worthwhile in UVHM (72 level cap)?
Answer: With good shock weapons and a Class Mod that boosts Shock damage you can deal insane damage. With a good Zapper class mod and 5 ranks in Wires Don't Talk you're dealing over 50% more damage with Shock, and Electrical Burn means it does a bit of extra damage to Flesh enemies.

The shock boosts also stack very well with Anarchy's effects; I survive quite well with 3 of 4 weapons being shock, due to the elemental damage boost there's rarely a reason to change weapons, especially with teammates about. And shock based badasses are pretty rare compared to fire and corrosive ones. Really the only significant limiting factor to the skill tree is you need at least decent shock weapons to make it work. Personally I use a shock Maliwan sniper rifle, a shock Dahl e-tech SMG (Dahl burst fire is immune to Anarchy's accuracy reduction by the way) and a shock Moxxie's Slow Hand.

Shock storm, One Two Boom and shock and auugh look cool but aren't as useful, and Strength of Five Gorillas isn't either as I usually don't use Death Trap that often (he gets in the way in co op). The entire tree is just there for Wires Don't Talk + Zapper class mod though. Maxing out the whole tree isn't as necessary, though Interspersed Outburst can be quite useful to slag enemies without having to use a slag weapon (no switching weapons is very nice), and Make it Sparkle also makes Deathtrap relatively useful since he can get situationally relevant elements in addition to the 3x straight-up damage boost.