**Reginald Crundall Punnett** FRS (Tonbridge, Kent, 20 June 1875 – Bilbrook, Somerset, 3 January 1967) was a British geneticist. He became Professor of Biology and then Professor of Genetics at the University of Cambridge.

He co-founded, with William Bateson, the *Journal of Genetics* in 1910. Punnett is probably best remembered today as the creator of the **Punnett square**, a tool still used by biologists to predict the probability of possible genotypes of offspring. His *Mendelism* (1905) is sometimes said to have been the first textbook on genetics; it was probably the first popular science book to introduce genetics to the public.

Life and work
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Reginald Punnett was born in 1875 in the town of Tonbridge in Kent, England. While recovering from a childhood bout of appendicitis, Punnett became acquainted with Jardine's Naturalist's Library and developed an interest in natural history. 

Attending the University of Cambridge, Punnett earned a degree in zoology in 1898, and a masters in 1902. Between these degrees he worked as a demonstrator and part-time lecturer at the University of St Andrews Natural History Department. However, by 1902 Punnett was back at Cambridge working in zoology, primarily the study of nematode worms. It was during this time that he and William Bateson began a research collaboration, which lasted several years.

When Punnett was an undergraduate, Gregor Mendel's work on inheritance was largely unknown and unappreciated by scientists. However, in 1900, Mendel's work was rediscovered. William Bateson became a proponent of Mendelian genetics, and had Mendel's work translated into English. It was with Bateson that Reginald Punnett helped establish the new science of genetics at Cambridge. He and Bateson co-discovered genetic linkage through experiments with chickens and pea plants.

In 1908, unable to explain how a dominant gene would not become fixed and ubiquitous in a population, Punnett introduced his problem to the mathematician G. H. Hardy, with whom he played cricket. Hardy went on to formulate what became known as the Hardy–Weinberg law.

In 1910 Punnett became professor of biology at Cambridge, and then the first Arthur Balfour Professor of Genetics when Bateson left in 1912. In the same year, Punnett was elected a Fellow of the Royal Society. He received the society's Darwin Medal in 1922.

During World War I, Punnett successfully applied his expertise to the problem of the early determination of gender in chickens. Since only females were used for egg-production, early identification of male chicks, which were destroyed or separated for fattening, meant that limited animal-feed and other resources could be used more efficiently. Punnett's work in this area was summarized in *Heredity in Poultry* (1923).

Punnett squares
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 Punnett square of one of Mendel's crosses, between parents heterozygous for the purple/white color alleles. Purple allele is dominant.
Punnett squares are used by biologists to determine the probability of offspring having a particular genotype.

|  | Maternal |
| --- | --- |
| B | b |
| Paternal | B | BB | Bb |
| b | Bb | bb |

If B represents the allele for having black hair and b represents the allele for having white hair, the offspring of two Bb parents would have a 25% probability of having two white hair alleles (bb), 50% of having one of each (Bb), and 25% of having only black hair alleles (BB). The phenotype (in this case the appearance) of the offspring would depend on whether and to what extent one of the alleles was dominant.

Selected writings
-----------------

  

* Punnett R.C. (1905). *Mendelism*. Cambridge: Bowes & Bowes. – a scanned copy of the second edition is here.

* Punnett, Reginald Crundall (1915). *Mimicry in butterflies*. Cambridge: Cambridge University Press. Retrieved 2008-05-11.

* *Heredity in Poultry* 1923

Further reading
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* Crew F. 1968. (1968). "R.C. Punnett". *Genetics*. **58** (1): 1–7. PMID 4872161.

* Hutt F. 1970. (1970). "Professor R.C. Punnett". *World's Poultry Science*. **26** (3): 696–700. doi:10.1017/S0043933900020006. PMID 4917050.

* Vijayraghavan K. 2006. (2006). "Punnett and duck genetics". *Journal of Genetics*. **85** (1): 3–7. doi:10.1007/BF02728963. PMID 16809833. S2CID 39644736.

Other websites
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* A brief biographical sketch of Punnett
* A briefer biographical sketch of Punnett Archived 2005-03-15 at the Wayback Machine
* A brief history of the University of Cambridge's Department of Genetics Archived 2009-03-09 at the Wayback Machine