American Bison Cured Meaty Large Knuckle Bone - Made in USA Natural American Bison Lrg Meaty Knuckle Bone (Not water buffalo). Cured at low temperatures, not baked to a crisp. We leave some moisture in the bones to keep them from becoming too brittle. Cured without Smoke or flavorings, just slow cured in their own natural juices. Made & Sourced in the USA from Free Range American Buffalo (Bison) raised without added hormones or antibiotics. Large - for Larger Sized Dogs Great alternative for dogs with allergies to beef or pork.