K9 ADVANTIX II FOR LARGE DOGS by K-9 Advantix kills and repels disease spreading fleas - ticks and mosquitoes K9 Advantix kills 98-100% of fleas within 12 hours K9 Advantix is for use on dogs and puppies 7 weeks of age or older. k9 advantix for dogs 21-55 pounds K9 advantix 4 pack