Spectra Sure Plus IGR Drops for 45-88 lb. Dogs (Generic Frontline) Contains fipronil & (S)-methoprene, the active ingredients used in Frontline Plus for Dogs Kills adult fleas, flea eggs, flea larvae and prevents the development of pupae for up to 12 weeks Kills brown dog ticks, American dog ticks, lone star ticks, and all stages of deer ticks Can be used on breeding, pregnant and lactating dogs Effective after bathing and exposure to water and sunlight