Frontline Plus for Dogs Large Dog (45 to 88 pounds) Flea and Tick Treatment, 6 Doses WATERPROOF FLEA AND TICK TREATMENT FOR DOGS: Frontline Plus for Dogs provides waterproof, fast-acting, long-lasting flea and tick treatment and control for your dog. This product is approved for use on dogs 45-88 lbs. BREAK THE FLEA LIFE CYCLE WITH FRONTLINE: Frontline flea and tick treatment for dogs kills adult fleas plus flea eggs and larvae to stop existing infestations and prevent establishment of new infestations. KILLS FLEAS AND TICKS: Frontline flea and tick treatment for dogs kills fleas, flea eggs, lice, and ticks. This flea and tick treatment kills ticks, including those that may transmit Lyme disease TRUSTED FLEA AND TICK PROTECTION FOR DOGS: Frontline has been trusted by veterinarians for nearly 20 years. Made with 2 tough killing ingredients, fipronil and (S)-methoprene  one to kill adult fleas and ticks and the second to kill flea eggs and larvae  this fast-acting, long-lasting protection provides flea and tick control for dogs and puppies 8 weeks and older. LASTING FLEA AND TICK PROTECTION: Frontline's long-lasting formula is stored in the oil glands of the pets skin to give non-stop flea and tick protection for a full 30 days. Frontline flea and tick treatment for dogs works non-stop for a full 30 days. A 6-dose supply lasts for 6 months.