C.E.T. Enzymatic Oral Hygiene Chews, Large Dogs, 15 Chews Combines natural antiseptic activity with abrasive action for clinically proven plaque control Exclusive Dual-Enzyme System eliminates plaque-forming bacteria Made using select beefhide, for veterinary use only Give your dog at least 1 chew daily to reduce plaque and calculus Please read all label information on delivery