Central Life Sciences 3-Pack Comfort Zone Refill with Dog Appeasing Pheromone, 144ml 3 pack of D.A.P refiils mimics a natural reassuring pheromone produced by female dogs when nursing Calms dogs during thunderstorms and fireworks or when left home alone Reduces or eliminates separation anxiety 3 pack of D.A.P refills mimics a natural reassuring pheromone produced by female dogs when nursing Calms dogs during thunderstorms and fireworks or when left home alone Reduces or eliminates separation anxiety 3 pack of D.A.P refills mimics a natural reassuring pheromone produced by female dogs when nursing