C.E.T. Enzymatic Oral Hygiene Chews for Large-Dogs-Super Size Value Package -150 Chews Combines natural antiseptic activity with abrasive action for clinically proven plaque control Exclusive Dual-Enzyme System eliminates plaque-forming bacteria Made using select beefhide, for veterinary use only Give your dog at least 1 chew daily to reduce plaque and calculus C.E.T. Enzymatic Oral Hygiene Chews for Large-Dogs-Super Size Value Package -150 Chews