Healthy Ponds 10145 Fountain Water Cleaner Refill 4 pack Healthy Ponds fountain water refill packs are safe for humans, pets, fish, and plants Each refill treats up to 25 gallons to provide a total of 120 days of treatment PRO formula works effectively in water from 34 to 110 degrees Fahrenheit May require 4-6 weeks to achieve water quality improvement Made in USA