Advantix DAV61642 Advantix 2 Dog / Size (Over 55 lbs) New and improved advantix 2 kills all flea and tick life stages. Prescription-free topical kills fleas, ticks, lice and mosquitoes. Repels biting flies, ticks and mosquites - common carriers of disease. Prevents eggs and immature forms from developing into adults. Protects with igr (insect growth regulator) pyripoxyfen.