Comfort Zone Dog Appeasing Pheromone Refill for Behavior Control 1.62oz (4 Pack) Pack of Four 1.62oz Comfort Zone Dog Appeasing Pheromone Refill for Behavior Control Reduce signs of stress associated with new puppy or shelter dog adoption or transition from a breeder Reduce signs of stress from loud noises such as fireworks or thunderstorms Clinically proven effective and veterinarian recommended; drug free