Virbac Epi-Soothe Shampoo, 16 oz Epi-Soothe shampoo for dogs, cats and horses. Epi-Soothe is a natural oat-grain derivative, soap-free shampoo designed for helping control itch. Epi-Soothe, using spherulites and chitosanide, represent a breakthrough in skin care technology. May be used as often as directed by your vet.