Chunky Chews&reg; 7"-8" Glucosamine Natural Rawhide Safety-Knot&reg; Bone for Large Dogs 100% Premium Rawhide with patented Safety-Knot design helps prolong chewing. Fortified with Glucosamine for optimal joint health. Made with grass-fed free-range beef hides. Antibiotic & hormone free. Contains Conjugated Linoleic Acid (CLA) an Omega-6 fatty acid for healthy skin and coat. Designed for big dogs and aggressive chewers.