Newton Lady Issac Neutral Guidance Running Shoes Action/ReactionTM Technology in the Midsole - Absorbs impact and adds responsiveness through the patented dynamic movement system. Midfoot Support Chassis - Provides added stability. Metatarsal Stretch Panels - For foot adjustment. Highly-Breathable - With closed mesh locks in ventilation and prohibits debris passing through the exterior. Slip-proof Laces - With heel-securing double eyelets present a secure, customizable fit.