Cadaflex Soft Chew with MSM Large Dog 150ct A comprehensive joint supplement formula containing high levels of GLUCOSAMINE HCL, CHONDROITIN SULFATE, and MSM. BOSWELLIA SERRATA EXTRACT as a COX-2 inhibitor which has been studied for its effects on COX-2 and LOX-5 enzymes and its ability to help maintain a normal inflammatory response in the joint TUMERIC which has been shown to be beneficial in supporting the synthesis of the intracellular antioxidant glutathione High Potency OMEGA-3 Fatty acids derived from cold water fish to help support joint, immune and skin/coat function