| 1 | A | B | C | D | E | F | G | H |
| --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 2 | component costs per 1,000 women over a lifetime, by screening strategy |  |  |  |  |  |  |  |
| 3 | screening strategy | screening | diagnostic and clinical work-up | surgical and radiation | adjuvant medication | indirect | overall cost | additional cost of premature death |
| 4 | no screening | $0 | $83,936 | $1,220,608 | $1,713,473 | $1,856,569 | $4,874,587 | $12,671,495 |
| 5 | annual ages 40 to 69 | $6,540,531 | $40,605 | $1,530,563 | $1,694,982 | $4,864,284 | $14,670,965 | $6,180,986 |
| 6 | annual ages 40 to 74 | $7,314,735 | $30,529 | $1,618,139 | $1,707,003 | $5,322,003 | $15,992,409 | $5,794,587 |
| 7 | annual ages 50 to 69 | $4,127,472 | $47,245 | $1,487,568 | $1,713,469 | $3,904,655 | $11,280,409 | $7,847,010 |
| 8 | annual ages 50 to 74 | $4,908,452 | $37,013 | $1,575,399 | $1,724,528 | $4,364,947 | $12,610,339 | $7,408,591 |
| 9 | biennial ages 50 to 69 | $2,175,956 | $55,863 | $1,437,689 | $1,807,948 | $3,019,322 | $8,496,778 | $9,261,094 |
| 10 | biennial ages 50 to 74 | $2,672,157 | $46,018 | $1,524,021 | $1,849,832 | $3,350,174 | $9,442,203 | $8,866,323 |
| 11 | triennial ages 50 to 69 | $1,573,325 | $61,405 | $1,406,127 | $1,821,409 | $2,724,921 | $7,587,187 | $10,085,986 |
| 12 | triennial ages 50 to 74 | $1,911,210 | $53,721 | $1,477,251 | $1,864,335 | $2,964,934 | $8,271,452 | $9,778,164 |
| 13 | annual ages 40 to 49/ biennial ages 50 to 69 | $4,551,101 | $49,334 | $1,479,841 | $1,788,107 | $3,985,553 | $11,853,937 | $7,552,892 |
| 14 | annual ages 40 to 49/biennial ages 50 to 74 | $5,027,968 | $39,529 | $1,567,832 | $1,832,766 | $4,316,621 | $12,784,716 | $7,130,482 |
| 15 | annual ages 40 to 49 | $2,484,365 | $75,590 | $1,276,581 | $1,705,534 | $2,848,195 | $8,390,266 | $10,795,828 |

Question: what is the range of the overall costs for annual screening of 1,000 women in the general population?
Answer: $11,280,409, $15,992,409

Question: what is the range of the overall costs for triennial screening of 1,000 women?
Answer: $7,587,187, $8,271,452

Question: what is the overall cost of no screening for 1,000 women over a lifetime?
Answer: $4,874,587